Phase 1-2 trial of PTK787/ZK222584 combined with intravenous doxorubicin for treatment of patients with advanced hepatocellular carcinoma

Cancer

Volumn 116, Issue 21, 2010, Pages 5022-5029

  Yau, Thomas ^a   Chan, Pierre ^a   Pang, Roberta ^a   Ng, Kelvin ^a   Fan, S T ^a   Poon, Ronnie T ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Advanced hepatocellular carcinoma; Angiogenesis; Doxorubicin; PTK787

Indexed keywords

DOXORUBICIN; VATALANIB;

ABDOMINAL PAIN; ADULT; ADVANCED CANCER; AGED; ALOPECIA; ANEMIA; ARTICLE; BLEEDING; BOLUS INJECTION; CANCER SURVIVAL; CEREBELLUM HEMORRHAGE; CLINICAL ARTICLE; CLINICAL TRIAL; DIARRHEA; DISEASE FREE SURVIVAL; DRUG DOSE ESCALATION; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; GASTROINTESTINAL HEMORRHAGE; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HEPATITIS B; HUMAN; HYPERTENSION; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MALAISE; MALE; MAXIMUM TOLERATED DOSE; MUCOSA INFLAMMATION; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUTROPENIA; OVERALL SURVIVAL; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; RASH; SEPSIS; THROMBOCYTOPENIA;

ADULT; AGED; ANGIOGENESIS INHIBITORS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, HEPATOCELLULAR; DOXORUBICIN; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; LIVER NEOPLASMS; MALE; MIDDLE AGED; PHTHALAZINES; PYRIDINES;

EID: 78249288161     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.25372     Document Type: Article

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