Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by αvβ and α5β1 integrins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 8, 2003, Pages 4766-4771

  Sudhakar, Akulapalli ^a   Sugimoto, Hikaru ^a   Yang, Changqing ^a   Lively, Julie ^a   Zeisberg, Michael ^a   Kalluri, Raghu ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ARGINYLGLYCYLASPARTIC ACID; BINDING PROTEIN; ENDOSTATIN; FIBRONECTIN; FOCAL ADHESION KINASE; INITIATION FACTOR 4E BINDING PROTEIN 1; INTEGRIN; INTEGRIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN CAP; PROTEIN KINASE B; RAF PROTEIN; TUMSTATIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5; VITRONECTIN; VITRONECTIN RECEPTOR;

APOPTOSIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENDOTHELIUM CELL; ENZYME INHIBITION; EVALUATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

AMINO ACID SEQUENCE; AUTOANTIGENS; BINDING, COMPETITIVE; CELLS, CULTURED; COLLAGEN; COLLAGEN TYPE IV; COLLAGEN TYPE XVIII; ENDOSTATINS; ENDOTHELIUM, VASCULAR; FIBRONECTINS; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; INTEGRIN ALPHA5BETA1; INTEGRIN ALPHAVBETA3; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NEOVASCULARIZATION, PATHOLOGIC; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN-TYROSINE KINASES; RECOMBINANT PROTEINS; VITRONECTIN;

EID: 0037446897     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0730882100     Document Type: Article

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