Grape antioxidant dietary fibre prevents mitochondrial apoptotic pathways by enhancing Bcl-2 and Bcl-xL expression and minimising oxidative stress in rat distal colonic mucosa

British Journal of Nutrition

Volumn 109, Issue 1, 2013, Pages 4-16

  López Oliva, María Elvira ^a   Pozuelo, María José ^b   Rotger, Rafael ^a   Muñoz Martínez, Emilia ^a   Goñi, Isabel ^c  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSIDAD SAN PABLO CEU   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Antioxidant dietary fibre; Apoptosis; Colonic mucosa; Redox status

Indexed keywords

CASPASE 3; CELLULOSE; CYTOCHROME C; GLUTATHIONE DISULFIDE; PROTEIN BCL 2; PROTEIN BCL XL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; B CELL LYMPHOMA; CELL PROLIFERATION; COLON MUCOSA; CONTROLLED STUDY; CRYPT CELL; CYTOSOLIC FRACTION; DIETARY FIBER; DOWN REGULATION; ENZYME ACTIVITY; GRAPE ANTIOXIDANT DIETARY FIBER; LIPID PEROXIDATION; MALE; MOLECULAR MODEL; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; COLON; CYTOSOL; DIETARY FIBER; DOWN-REGULATION; FRUIT; GLUTATHIONE; INTESTINAL MUCOSA; LIPID PEROXIDATION; MALE; MITOCHONDRIA; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; RANDOM ALLOCATION; RATS; RATS, WISTAR; UP-REGULATION; VITIS;

RATTUS; RATTUS NORVEGICUS; VITACEAE;

EID: 84872017267     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114512000517     Document Type: Article

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