Chemical derivatization to enhance ionization of anabolic steroids in LC-MS for doping-control analysis

TrAC - Trends in Analytical Chemistry

Volumn 42, Issue , 2013, Pages 137-156

  Athanasiadou, Ioanna ^a,b   Angelis, Yiannis S ^a   Lyris, Emmanouil ^a   Georgakopoulos, Costas ^a,c  

^a Olympic Athletic Center of Athens   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

^c Anti Doping Lab Qatar   (Qatar)

Author keywords

Anabolic steroids; Chemical derivatization; Doping control; Electrospray ionization (ESI); Ionization; LC MS; Liquid chromatography; Mass spectrometry; Minimum required performance limit (MRPL); Sensitivity

Indexed keywords

ATMOSPHERIC IONIZATION; ATMOSPHERIC PRESSURE; ELECTROSPRAY IONIZATION; IONIZATION; LIPIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ORGANIC POLYMERS; SPORTS;

ANABOLIC STEROID; CHEMICAL DERIVATIZATION; DOPING CONTROL; LC-MS; MINIMUM REQUIRED PERFORMANCE LIMITS; SENSITIVITY;

CHEMICAL ANALYSIS;

(4 HYDRAZINO 4 OXOBUTYL); 1 (2,4 DINITRO 5 FLUOROPHENYL) 4,4 METHYLPIPERAZINE; 1,2 BENZO 3,4 DIHYDROCARBAZOLE 9 ETHYL BENZENESULFONIC ACID; 2 FLUORO 1 METHYLPYRIDINIUM PARA TOLUENE SULFONIC ACID; 2 HYDRAZINO 1 METHYLPYRIDIN; 2 HYDRAZINO PYRIDIN; 2 PICOLYLAMINE; 2,3 PYRIDINDICARBOXYLIC ANHYDRIDE; 3,5 DINITROBENZOYL CHLORIDE; 4 NITROBENZENESULFONYL CHLORIDE; 4 NITROBENZOYL; 4 NITROBENZOYL CHLORIDE; ANABOLIC AGENT; CHLORIDE; DANSYL CHLORIDE; FUSARIC ACID; HYDROXYLAMINE; ISONICOTINOYL AZIDE; METHOXYAMINE; N,N PYRIDINDICARBOXYLIC ANHYDRIDE; ORTHO ETHOXYAMINE; PARA TOLUENESULFONYL ISOCYANIC ACID; PENTAFLUOROPHENYL HYDRAZINE; PHOSPHONIUM ACETATE BROMIDE; PICOLINIC ACID; PYRIDIN 3 SULFONYL CHLORIDE; REAGENT; UNCLASSIFIED DRUG; [3 (2 NITRO 4 TRIFLUOROMETHYLPHENYL)AMINOPHENYL]DIHYDROXY BORANE; [TRIS(2,4,6 TRIMETHOXYPHENYL)]PHOSPHONIUM BROMIDE;

ANALYTIC METHOD; ATMOSPHERIC PRESSURE IONIZATION MASS SPECTROMETRY; CHEMICAL STRUCTURE; DERIVATIZATION; DOPING; ELECTROSPRAY MASS SPECTROMETRY; EQUESTRIAN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SENSITIVITY ANALYSIS; SPORT; TRIPLE QUADRUPOLE MASS SPECTROMETER; URINE;

EID: 84871513259     PISSN: 01659936     EISSN: 18793142     Source Type: Journal    
DOI: 10.1016/j.trac.2012.10.003     Document Type: Review

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