Salivary chenodeoxycholic acid and its glycine-conjugate: Their determination method using LC-MS/MS and variation of their concentrations with increased saliva flow rate

Steroids

Volumn 75, Issue 4-5, 2010, Pages 338-345

  Higashi, Tatsuya ^a   Shibayama, Yujin ^b   Ichikawa, Takuya ^a   Ito, Koichi ^a   Toyo'oka, Toshimasa ^a   Shimada, Kazutake ^b   Mitamura, Kuniko ^c   Ikegawa, Shigeo ^c   Chiba, Hitoshi ^d  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c KINKI UNIVERSITY   (Japan)

^d HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Bile acid; Derivatization; Liquid chromatography mass spectrometry; Saliva; Saliva flow rate

Indexed keywords

ALCOHOL; CHENODEOXYCHOLIC ACID; GLYCOCHENODEOXYCHOLIC ACID; HYDRAZIDE DERIVATIVE; PYRIDINE DERIVATIVE;

ADULT; ARTICLE; BIOTRANSFORMATION; CHEMICAL REACTION; CHEWING GUM; CONTROLLED STUDY; DERIVATIZATION; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; ELECTROSPRAY MASS SPECTROMETRY; FLOW RATE; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MALE; MASTICATION; NORMAL HUMAN; REPRODUCIBILITY; SALIVA ANALYSIS; SALIVA LEVEL; SALIVATION; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

ADULT; CHENODEOXYCHOLIC ACID; CHEWING GUM; CHROMATOGRAPHY, LIQUID; FEMALE; GLYCINE; HUMANS; MALE; REPRODUCIBILITY OF RESULTS; SALIVA; SALIVATION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TIME FACTORS; YOUNG ADULT;

EID: 77949267170     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2010.01.015     Document Type: Article

References (22)

1. Hofmann A.F., and Hagey L.R. Bile acids: chemistry, pathochemistry, biology, pathobiology, and therapeutics. Cell Mol Life Sci 65 (2008) 2461-2483
2. Makishima M., Okamoto A.Y., Repa J.J., Tu H., Learned R.M., Luk A., et al. Identification of a nuclear receptor for bile acids. Science 284 (1999) 1362-1365
3. Lewis J.G. Steroid analysis in saliva: an overview. Clin Biochem Rev 27 (2006) 139-146
4. Chiappin S., Antonelli G., Gatti R., and De Palo E.F. Saliva specimen: a new laboratory tool for diagnostic and basic investigation. Clin Chim Acta 383 (2007) 30-40
5. Kiess W., and Pfaeffle R. Steroid analysis in saliva: a noninvasive tool for pediatric research and clinical practice. J Pediatr 83 (2007) 97-99
6. Gröschl M. Current status of salivary hormone analysis. Clin Chem 54 (2008) 1759-1769
7. Vining R.F., and McGinley R.A. The measurement of hormones in saliva: possibilities and pitfalls. J Steroid Biochem 27 (1987) 81-94
8. Gröschl M., and Rauh M. Influence of commercial collection devices for saliva on the reliability of salivary steroids analysis. Steroids 71 (2006) 1097-1100
9. Gröschl M., Köhler H., Topf H.G., Rupprecht T., and Rauh M. Evaluation of saliva collection devices for the analysis of steroids, peptides and therapeutic drugs. J Pharm Biomed Anal 47 (2008) 478-486
10. Atkinson K.R., Lo K.R., Payne S.R., Mitchell J.S., and Ingram J.R. Rapid saliva processing techniques for near real-time analysis of salivary steroids and protein. J Clin Lab Anal 22 (2008) 395-402
11. Higashi T., Shibayama Y., and Shimada K. Determination of salivary dehydroepiandrosterone using liquid chromatography-tandem mass spectrometry combined with charged derivatization. J Chromatogr B 846 (2007) 195-201
12. Vining R.F., McGinley R.A., and Symons R.G. Hormones in saliva: mode of entry and consequent implications for clinical interpretation. Clin Chem 29 (1983) 1752-1756
13. Li P.K., Pillai R., and Dibbelt L. Estrone sulfate analogs as estrone sulfatase inhibitors. Steroids 60 (1995) 299-306
14. Hedenborg G., Norlander A., and Norman A. Bile acids in serum, ultrafiltrate of serum and saliva from patients with cholestatic jaundice. Scand J Clin Lab Invest 47 (1987) 83-89
15. Higashi T., Shibayama Y., Kawasaki I., and Shimada K. Determination of salivary 17-ketosteroid sulfates using liquid chromatography-electrospray ionization-mass spectrometry. J Pharm Biomed Anal 43 (2007) 1782-1788
16. Shibayama Y., Higashi T., Shimada K., Odani A., Mizokami A., Konaka H., et al. Simultaneous determination of salivary testosterone and dehydroepiandrosterone using LC-MS/MS: method development and evaluation of applicability for diagnosis and medication for late-onset hypogonadism. J Chromatogr B 877 (2009) 2615-2623
17. Toyo'oka T., Ishibashi M., Takeda Y., Nakashima K., and Imai K. Precolumn fluorescence tagging reagent for carboxylic acids in high-performance liquid chromatography: 4-substituted-7-aminoalkylamino-2,1,3-benzoxadiazoles. J Chromatogr 588 (1991) 61-71
18. 2), and its application to capillary electrophoresis with laser-induced fluorescence detection. Biomed Chromatogr 16 (2002) 523-528
19. Arregger A.L., Contreras L.N., Tumilasci O.R., Aquilano D.R., and Cardoso E.M. Salivary testosterone: a reliable approach to the diagnosis of male hypogonadism. Clin Endocrinol 67 (2007) 656-662
20. Roda A., Minutello A., Angellotti M.A., and Fini A. Bile acid structure-activity relationship: evaluation of bile acid lipophilicity using 1-octanol/water partition coefficient and reverse phase HPLC. J Lipid Res 31 (1990) 1433-1443
21. Alvarez Núñez F.A., and Yalkowsky S.H. Correlation between log P and ClogP for some steroids. J Pharm Sci 86 (1997) 1187-1189
22. Ikegawa S., Yanagihara T., Murao N., Watanabe H., Goto J., and Niwa T. Separatory determination of bile acid 3-sulfates by liquid chromatography/electrospray ionization mass spectrometry. J Mass Spectrom 32 (1997) 401-407