Detection of altrenogest and its metabolites in post administration horse urine using liquid chromatography tandem mass spectrometry - Increased sensitivity by chemical derivatisation of the glucuronic acid conjugate

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 833, Issue 2, 2006, Pages 245-256

  Lampinen Salomonsson, Matilda ^a   Beckman, Elin ^a   Bondesson, Ulf ^a,b   Hedeland, Mikael ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b NATIONAL VETERINARY INSTITUTE   (Sweden)

Author keywords

Altrenogest; Conjugate; Derivatisation; Doping control; Glucuronide; Horse urine; LC MS MS; Metabolism; Sulfate

Indexed keywords

DISSOCIATION; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM;

ALTRENOGEST; CONJUGATE; DERIVATISATION; DOPING CONTROL; GLUCURONIDE; HORSE URINE; LC-MS/MS; SULFATES;

METABOLITES;

AGLYCONE; ALTRENOGEST; DRUG METABOLITE; GLUCURONIC ACID; REGU MATE; TRENBOLONE;

ANIMAL EXPERIMENT; ARTICLE; COLLISIONALLY ACTIVATED DISSOCIATION; CONTROLLED STUDY; DERIVATIZATION; DRUG DETERMINATION; DRUG METABOLISM; DRUG URINE LEVEL; ELECTROSPRAY; HORSE; LIQUID CHROMATOGRAPHY; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, LIQUID; GLUCURONIC ACID; HORSES; MOLECULAR WEIGHT; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRENBOLONE;

ANIMALIA; EQUIDAE; EQUUS CABALLUS;

EID: 33645230359     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.02.014     Document Type: Article

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