Development of a highly sensitive and selective UPLC/MS/MS method for the simultaneous determination of testosterone and 5α-dihydrotestosterone in human serum to support testosterone replacement therapy for hypogonadism

Steroids

Volumn 73, Issue 6, 2008, Pages 601-610

  Licea Perez, Hermes ^a   Wang, Sherry ^a   Szapacs, Matthew E ^a   Yang, Eric ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Derivatization, 2,3 Pyridinedicarboxilic anhydride; Dihydrotestosterone; Testosterone; UPLC, Surrogate Matrix

Indexed keywords

2,3 PYRIDINEDICARBOXYLIC ANHYDRIDE; ACID ANHYDRIDE; ANDROSTANOLONE; STEROID; TESTOSTERONE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; HORMONE SUBSTITUTION; HUMAN; HYPOGONADISM; LIQUID LIQUID EXTRACTION; MASS SPECTROMETRY; SOLID PHASE EXTRACTION;

CHROMATOGRAPHY, LIQUID; DIHYDROTESTOSTERONE; HORMONE REPLACEMENT THERAPY; HUMANS; HYPOGONADISM; MALE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TESTOSTERONE;

EID: 41749097837     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2008.01.018     Document Type: Article

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