Development of sensitive derivatization method for aldosterone in liquid chromatography-electrospray ionization tandem mass spectrometry of corticosteroids

Journal of Chromatography A

Volumn 1200, Issue 2, 2008, Pages 114-121

  Yamashita, Kouwa ^a   Okuyama, Mitsunobu ^b   Nakagawa, Risa ^b   Honma, Seijiro ^b   Satoh, Fumitoshi ^c   Morimoto, Ryo ^c   Ito, Sadayoshi ^c   Takahashi, Madoka ^a   Numazawa, Mitsuteru ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^b Grelan Pharmaceutical Co Ltd   (Japan)

^c TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Aldosterone; Derivatization; Electrospray ionization tandem mass spectrometry; High performance liquid chromatography; Picolinyl ester

Indexed keywords

BODY FLUIDS; CHEMICAL MODIFICATION; CHEMICAL REACTIONS; CHEMICALS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; ESTERS; ETHANOL; ETHERS; FLUIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIZATION; IONIZATION OF LIQUIDS; MASS SPECTROMETERS; MASS SPECTROMETRY; ORGANIC COMPOUNDS; SPECTROMETERS; SPECTROMETRY; SPECTRUM ANALYSIS; TURBULENT FLOW;

2 METHYL 6 NITROBENZOIC ANHYDRIDE; 4-DIMETHYLAMINOPYRIDINE (DMAP); CORTICOSTEROIDS (CORT); DERIVATIZATION; DERIVATIZATION METHOD; ELECTROSPRAY (ES); ESI MASS SPECTRUM; ETHYL ETHER; HIGHLY SENSITIVE; LC ESI MS/MS; PICOLINIC ACID; POSITIVE MODE; PROTONATED; QUANTIFICATION METHODS; TANDEM MASS SPECTROMETRY (MS/MS);

LIQUID CHROMATOGRAPHY;

2 METHYL 6 NITROBENZOIC ANHYDRIDE; 4 DIMETHYLAMINOPYRIDINE; ACID ANHYDRIDE; ALCOHOL; ALDOSTERONE; CORTICOSTEROID DERIVATIVE; CORTICOSTERONE; CORTODOXONE; DEHYDROCORTICOSTERONE; ETHER; ETHYL ETHER PICOLINYL; HYDROCHLORIC ACID; PICOLINIC ACID; PICOLINIC ACID DERIVATIVE;

ACCURACY; ARTICLE; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; ESTERIFICATION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID CHROMATOGRAPHY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; TANDEM MASS SPECTROMETRY;

ADRENAL CORTEX HORMONES; ALDOSTERONE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ETHANOL; HUMANS; HYDROCHLORIC ACID; MOLECULAR STRUCTURE; PICOLINIC ACIDS; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 46049093356     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2008.05.034     Document Type: Article

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