Studies on neurosteroids XIX. Development and validation of liquid chromatography-tandem mass spectrometric method for determination of 5α-reduced pregnane-type neurosteroids in rat brain and serum

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 848, Issue 2, 2007, Pages 188-199

  Higashi, Tatsuya ^a   Nagahama, Akihiro ^a   Otomi, Norihiro ^a   Shimada, Kazutake ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Derivatization; Ethanol administration; Immobilization stress; LC ESI MS MS; Neurosteroids; Rat brain

Indexed keywords

ETHANOL ADMINISTRATION; IMMOBILIZATION STRESS; NEUROSTEROIDS; RAT BRAIN;

BIOASSAY; BRAIN; ETHANOL; HORMONES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

BIOMEDICAL ENGINEERING;

2 HYDRAZINO 1 METHYLPYRIDINE; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 5ALPHA PREGNANE 3,20 DIONE; ALCOHOL; EPIALLOPREGNANOLONE; NEUROSTEROID; PREGNANE DERIVATIVE; REAGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATMOSPHERIC PRESSURE; BRAIN LEVEL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ELECTROSPRAY MASS SPECTROMETRY; HORMONE BLOOD LEVEL; IMMOBILIZATION STRESS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; RAT; REPRODUCIBILITY; STEROID BLOOD LEVEL; TANDEM MASS SPECTROMETRY;

ANIMALS; BRAIN; CHROMATOGRAPHY, LIQUID; MALE; MOLECULAR STRUCTURE; PREGNANES; RATS; RATS, WISTAR; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 33947406711     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.10.036     Document Type: Article

References (22)

1. Barbaccia M.L., Serra M., Purdy R.H., and Biggio G. Int. Rev. Neurobiol. 46 (2001) 243
2. Purdy R.H., Morrow A.L., Moore Jr. P.H., and Paul S.M. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 4553
3. Vallée M., Rivera J.D., Koob G.F., Purdy R.H., and Fitzgerald R.L. Anal. Biochem. 287 (2000) 153
4. Barbaccia M.L., Roscetti G., Trabucchi M., Purdy R.H., Mostallino M.C., Concas A., and Biggio G. Br. J. Pharmacol. 120 (1997) 1582
5. van Broekhoven F., and Verkes R.J. Psychopharmacology 165 (2003) 97
6. Barbaccia M.L., Affricano D., Trabucchi M., Purdy R.H., Colombo G., Agabio R., and Gessa G.L. Eur. J. Pharmacol. 384 (1999) R1
7. O'Dell L.E., Alomary A.A., Vallée M., Koob G.F., Fitzgerald R.L., and Purdy R.H. Eur. J. Pharmacol. 484 (2004) 241
8. Uzunov D.P., Cooper T.B., Costa E., and Guidotti A. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 12599
9. Bäckström T., Wahlström G., Wahlström K., Zhu D., and Wang M.-D. Eur. J. Pharmacol. 512 (2005) 15
10. Rupprecht R., and Holsboe F. Trends Neurosci. 22 (1999) 410
11. Higashi T., Takido N., and Shimada K. Steroids 70 (2005) 1
12. Liu S., Sjövall J., and Griffiths W.J. Anal. Chem. 75 (2003) 5835
13. Reddy D.S., Venkatarangan L., Chien B., and Ramu K. Steroids 70 (2005) 879
14. Leinonen A., Kuuranne T., and Kostiainen R. J. Mass Spectrom. 37 (2002) 693
15. Guo T., Chan M., and Soldin S.J. Arch. Pathol. Lab. Med. 128 (2004) 469
16. Higashi T., and Shimada K. Anal. Bioanal. Chem. 378 (2004) 875
17. Griffiths W.J., Liu S., Alvelius G., and Sjövall J. Rapid Commun. Mass Spectrom. 17 (2003) 924
18. Griffiths W.J., Alvelius G., Liu S., and Sjövall J. Eur. J. Mass Spectrom. 10 (2004) 63
19. Higashi T., Yamauchi A., and Shimada K. J. Chromatogr. B 825 (2005) 214
20. Dehennin L., Reiffsteck A., and Scholler R. Biomed. Mass Spectrom. 7 (1980) 493
21. Liere P., Akwa Y., Weill-Engerer S., Eychenne B., Pianos A., Robel P., Sjövall J., Schumacher M., and Baulieu E.-E. J. Chromatogr. B 739 (2000) 301
22. Ebner M.J., Corol D.I., Havlíková H., Honour J.W., and Fry J.P. Endocrinology 147 (2006) 179