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Volumn 93, Issue 1, 2013, Pages 46-56

Erratum: Prospects for Treatment of Latent HIV (Clinical Pharmacology and Therapeutics (2013) 93 (46-56) DOI: 10.1038/clpt.2012.202);Prospects for treatment of latent HIV

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; BRYOSTATIN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; DISULFIRAM; GIVINOSTAT; HEXAMETHYLENEBISACETAMIDE; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N (1 BENZYL 4 PIPERIDINYL) 2 (HEXAHYDRO 4 METHYL 1H 1,4 DIAZEPIN 1 YL) 6,7 DIMETHOXY 4 QUINAZOLINAMINE; PROGRAMMED DEATH 1 RECEPTOR; PROSTRATIN; PROTEIN KINASE C; UNCLASSIFIED DRUG; VALPROIC ACID; VORINOSTAT; ZINC FINGER NUCLEASE;

EID: 84871273863     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2013.19     Document Type: Erratum
Times cited : (77)

References (75)
  • 2
    • 73249136755 scopus 로고    scopus 로고
    • Molecular control of HIV-1 postintegration latency: Implications for the development of new therapeutic strategies
    • Colin, L. & Van Lint, C. Molecular control of HIV-1 postintegration latency: Implications for the development of new therapeutic strategies. Retrovirology 6, 111 (2009).
    • (2009) Retrovirology , vol.6 , pp. 111
    • Colin, L.1    Van Lint, C.2
  • 3
    • 0029919356 scopus 로고    scopus 로고
    • Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation
    • Van Lint, C., Emiliani, S., Ott, M. & Verdin, E. Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. EMBO J. 15, 1112-1120 (1996).
    • (1996) EMBO J. , vol.15 , pp. 1112-1120
    • Van Lint, C.1    Emiliani, S.2    Ott, M.3    Verdin, E.4
  • 4
    • 65349193781 scopus 로고    scopus 로고
    • A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression
    • Keedy, K.S., Archin, N.M., Gates, A.T., Espeseth, A., Hazuda, D.J. & Margolis, D.M. A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. J. Virol. 83, 4749-4756 (2009).
    • (2009) J. Virol , vol.83 , pp. 4749-4756
    • Keedy, K.S.1    Archin, N.M.2    Gates, A.T.3    Espeseth, A.4    Hazuda, D.J.5    Margolis, D.M.6
  • 5
    • 4143065816 scopus 로고    scopus 로고
    • Host cell gene expression during human immunodeficiency virus type 1 latency and reactivation and effects of targeting genes that are differentially expressed in viral latency
    • Krishnan, V. & Zeichner, S.L. Host cell gene expression during human immunodeficiency virus type 1 latency and reactivation and effects of targeting genes that are differentially expressed in viral latency. J. Virol. 78, 9458-9473 (2004).
    • (2004) J. Virol , vol.78 , pp. 9458-9473
    • Krishnan, V.1    Zeichner, S.L.2
  • 6
    • 23744500093 scopus 로고    scopus 로고
    • Depletion of latent HIV-1 infection in vivo: A proof-ofconcept study
    • Lehrman, G. et al. Depletion of latent HIV-1 infection in vivo: A proof-ofconcept study. Lancet 366, 549-555 (2005).
    • (2005) Lancet , vol.366 , pp. 549-555
    • Lehrman, G.1
  • 7
    • 84864203255 scopus 로고    scopus 로고
    • Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
    • Archin, N.M. et al. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature 487, 482-485 (2012).
    • (2012) Nature , vol.487 , pp. 482-485
    • Archin, N.M.1
  • 8
    • 33847642822 scopus 로고    scopus 로고
    • Stability of the latent reservoir for HIV-1 in patients receiving valproic acid
    • Siliciano, J.D. et al. Stability of the latent reservoir for HIV-1 in patients receiving valproic acid. J. Infect. Dis. 195, 833-836 (2007).
    • (2007) J. Infect. Dis , vol.195 , pp. 833-836
    • Siliciano, J.D.1
  • 9
    • 79957934393 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors for purging HIV-1 from the latent reservoir
    • Matalon, S., Rasmussen, T.A. & Dinarello, C.A. Histone deacetylase inhibitors for purging HIV-1 from the latent reservoir. Mol. Med. 17, 466-472 (2011).
    • (2011) Mol. Med , vol.17 , pp. 466-472
    • Matalon, S.1    Rasmussen, T.A.2    Dinarello, C.A.3
  • 12
    • 79955552937 scopus 로고    scopus 로고
    • Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis
    • Vojinovic, J. et al. Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis. Arthritis Rheum. 63, 1452-1458 (2011).
    • (2011) Arthritis Rheum , vol.63 , pp. 1452-1458
    • Vojinovic, J.1
  • 13
    • 79957933972 scopus 로고    scopus 로고
    • Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat)
    • Furlan, A. et al. Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat). Mol. Med. 17, 353-362 (2011).
    • (2011) Mol. Med , vol.17 , pp. 353-362
    • Furlan, A.1
  • 14
    • 0037022598 scopus 로고    scopus 로고
    • The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines
    • Leoni, F. et al. The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines. Proc. Natl. Acad. Sci. USA 99, 2995-3000 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 2995-3000
    • Leoni, F.1
  • 16
    • 79958136377 scopus 로고    scopus 로고
    • Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation
    • Xing, S. et al. Disulfiram reactivates latent HIV-1 in a Bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation. J. Virol. 85, 6060-6064 (2011).
    • (2011) J. Virol , vol.85 , pp. 6060-6064
    • Xing, S.1
  • 17
    • 84872393902 scopus 로고    scopus 로고
    • Disulfiram reactivates latent HIV-1 expression through depletion of the phosphatase and tensin homolog (PTEN)
    • e-pub ahead of print 27 June 2012
    • Doyon, G., Zerbato, J., Mellors, J.W. & Sluis-Cremer, N. Disulfiram reactivates latent HIV-1 expression through depletion of the phosphatase and tensin homolog (PTEN). AIDS (2012); e-pub ahead of print 27 June 2012
    • (2012) AIDS
    • Doyon, G.1    Zerbato, J.2    Mellors, J.W.3    Sluis-Cremer, N.4
  • 18
    • 84872396740 scopus 로고    scopus 로고
    • Safety and feasibility of using disulfiram to enhance HIV transcription among long-term ARV-treated adults: Preliminary results from a pilot study
    • Seattle, W.A. March 2012
    • Spivak, A. et al. Safety and feasibility of using disulfiram to enhance HIV transcription among long-term ARV-treated adults: Preliminary results from a pilot study. 19th Conference on Retroviruses and Opportunistic Infections, Seattle, WA, 5-8 March 2012
    • 19th Conference on Retroviruses and Opportunistic Infections , pp. 5-8
    • Spivak, A.1
  • 19
    • 84873715778 scopus 로고    scopus 로고
    • Purging the HIV-1 reservoir through disruption of the PD-1 pathway
    • Boston, MA, 27 February-2 March 2011
    • Da Fonseca, S. et al. Purging the HIV-1 reservoir through disruption of the PD-1 pathway. 18th Conference on Retroviruses and Opportunistic Infections, Boston, MA, 27 February-2 March 2011
    • 18th Conference on Retroviruses and Opportunistic Infections
    • Da Fonseca, S.1
  • 20
    • 73149113364 scopus 로고    scopus 로고
    • Influence of a vaccination schedule on viral load rebound and immune responses in successfully treated HIV-infected patients
    • Castro, P. et al. Influence of a vaccination schedule on viral load rebound and immune responses in successfully treated HIV-infected patients. AIDS Res. Hum. Retroviruses 25, 1249-1259 (2009).
    • (2009) AIDS Res. Hum. Retroviruses , vol.25 , pp. 1249-1259
    • Castro, P.1
  • 21
    • 80855132756 scopus 로고    scopus 로고
    • Effect of therapeutic HIV recombinant poxvirus vaccines on the size of the resting CD4+ T-cell latent HIV reservoir
    • Persaud, D. et al. Effect of therapeutic HIV recombinant poxvirus vaccines on the size of the resting CD4+ T-cell latent HIV reservoir. AIDS 25, 2227-2234 (2011).
    • (2011) AIDS , vol.25 , pp. 2227-2234
    • Persaud, D.1
  • 23
    • 0342742310 scopus 로고
    • Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B
    • Osborn, L., Kunkel, S. & Nabel, G.J. Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B. Proc. Natl. Acad. Sci. USA. 86, 2336-2340 (1989).
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2336-2340
    • Osborn, L.1    Kunkel, S.2    Nabel, G.J.3
  • 24
    • 4744359117 scopus 로고    scopus 로고
    • Prostratin antagonizes HIV latency by activating NFkappaB
    • Williams, S.A. et al. Prostratin antagonizes HIV latency by activating NFkappaB. J. Biol. Chem. 279, 42008-42017 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 42008-42017
    • Williams, S.A.1
  • 25
    • 0026113987 scopus 로고
    • Distinct modulatory effects of bryostatin 1 and staurosporine on the biosynthesis and expression of the HIV receptor protein (CD4) by T cells
    • Boto, W.M., Brown, L., Chrest, J. & Adler, W.H. Distinct modulatory effects of bryostatin 1 and staurosporine on the biosynthesis and expression of the HIV receptor protein (CD4) by T cells. Cell Regul. 2, 95-103 (1991).
    • (1991) Cell Regul , vol.2 , pp. 95-103
    • Boto, W.M.1    Brown, L.2    Chrest, J.3    Adler, W.H.4
  • 26
    • 67650550767 scopus 로고    scopus 로고
    • Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: Implications for treatment of latent infection
    • Reuse, S. et al. Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: Implications for treatment of latent infection. PLoS ONE 4, e6093 (2009).
    • (2009) PLoS ONE , vol.4
    • Reuse, S.1
  • 27
    • 77955287402 scopus 로고    scopus 로고
    • Bryostatin modulates latent HIV-1 infection via PKC and AMPK signaling but inhibits acute infection in a receptor independent manner
    • Mehla, R. et al. Bryostatin modulates latent HIV-1 infection via PKC and AMPK signaling but inhibits acute infection in a receptor independent manner. PLoS ONE 5, e11160 (2010).
    • (2010) PLoS ONE , vol.5
    • Mehla, R.1
  • 28
    • 84862295855 scopus 로고    scopus 로고
    • Phase II trial of bryostatin-1 in combination with cisplatin in patients with recurrent or persistent epithelial ovarian cancer: A California cancer consortium study
    • Morgan, R.J. Jr et al. Phase II trial of bryostatin-1 in combination with cisplatin in patients with recurrent or persistent epithelial ovarian cancer: A California cancer consortium study. Invest. New Drugs 30, 723-728 (2012).
    • (2012) Invest. New Drugs , vol.30 , pp. 723-728
    • Morgan Jr., R.J.1
  • 29
    • 42549086792 scopus 로고    scopus 로고
    • Hexamethylbisacetamide and disruption of human immunodeficiency virus type 1 latency in CD4(+) T cells
    • Choudhary, S.K., Archin, N.M. & Margolis, D.M. Hexamethylbisacetamide and disruption of human immunodeficiency virus type 1 latency in CD4(+) T cells. J. Infect. Dis. 197, 1162-1170 (2008).
    • (2008) J. Infect. Dis , vol.197 , pp. 1162-1170
    • Choudhary, S.K.1    Archin, N.M.2    Margolis, D.M.3
  • 30
    • 33646172635 scopus 로고    scopus 로고
    • Hexamethylbisacetamide remodels the human immunodeficiency virus type 1 (HIV-1) promoter and induces Tat-independent HIV-1 expression but blunts cell activation
    • Klichko, V., Archin, N., Kaur, R., Lehrman, G. & Margolis, D. Hexamethylbisacetamide remodels the human immunodeficiency virus type 1 (HIV-1) promoter and induces Tat-independent HIV-1 expression but blunts cell activation. J. Virol. 80, 4570-4579 (2006).
    • (2006) J. Virol , vol.80 , pp. 4570-4579
    • Klichko, V.1    Archin, N.2    Kaur, R.3    Lehrman, G.4    Margolis, D.5
  • 31
    • 36048945927 scopus 로고    scopus 로고
    • HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription
    • Contreras, X., Barboric, M., Lenasi, T. & Peterlin, B.M. HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription. PLoS Pathog. 3, 1459-1469 (2007).
    • (2007) PLoS Pathog , vol.3 , pp. 1459-1469
    • Contreras, X.1    Barboric, M.2    Lenasi, T.3    Peterlin, B.M.4
  • 32
    • 0026446246 scopus 로고
    • Hexamethylene bisacetamide in myelodysplastic syndrome and acute myelogenous leukemia: A phase II clinical trial with a differentiation-inducing agent
    • Andreeff, M. et al. Hexamethylene bisacetamide in myelodysplastic syndrome and acute myelogenous leukemia: A phase II clinical trial with a differentiation-inducing agent. Blood 80, 2604-2609 (1992).
    • (1992) Blood , vol.80 , pp. 2604-2609
    • Andreeff, M.1
  • 33
    • 77957730576 scopus 로고    scopus 로고
    • Cell line-dependent variability in HIV activation employing DNMT inhibitors
    • Fernandez, G. & Zeichner, S.L. Cell line-dependent variability in HIV activation employing DNMT inhibitors. Virol. J. 7, 266 (2010).
    • Virol. J. , vol.7 , Issue.266 , pp. 2010
    • Fernandez, G.1    Zeichner, S.L.2
  • 34
    • 80052287096 scopus 로고    scopus 로고
    • Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2
    • Friedman, J. et al. Epigenetic silencing of HIV-1 by the histone H3 lysine 27 methyltransferase enhancer of Zeste 2. J. Virol. 85, 9078-9089 (2011).
    • (2011) J. Virol , vol.85 , pp. 9078-9089
    • Friedman, J.1
  • 35
    • 84862907673 scopus 로고    scopus 로고
    • Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation
    • Xing, S. et al. Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation. J. Antimicrob. Chemother. 67, 398-403 (2012).
    • (2012) J. Antimicrob. Chemother , vol.67 , pp. 398-403
    • Xing, S.1
  • 36
    • 79958739925 scopus 로고    scopus 로고
    • High-throughput screening uncovers a compound that activates latent HIV-1 and acts cooperatively with a histone deacetylase (HDAC) inhibitor
    • Micheva-Viteva, S. et al. High-throughput screening uncovers a compound that activates latent HIV-1 and acts cooperatively with a histone deacetylase (HDAC) inhibitor. J. Biol. Chem. 286, 21083-21091 (2011).
    • (2011) J. Biol. Chem , vol.286 , pp. 21083-21091
    • Micheva-Viteva, S.1
  • 37
    • 34347398120 scopus 로고    scopus 로고
    • HIV-1 proviral DNA excision using an evolved recombinase
    • Sarkar, I., Hauber, I., Hauber, J. & Buchholz, F. HIV-1 proviral DNA excision using an evolved recombinase. Science 316, 1912-1915 (2007).
    • (2007) Science , vol.316 , pp. 1912-1915
    • Sarkar, I.1    Hauber, I.2    Hauber, J.3    Buchholz, F.4
  • 38
    • 84856895124 scopus 로고    scopus 로고
    • Excision of HIV-1 proviral DNA by recombinant cell permeable tre-recombinase
    • Mariyanna, L. et al. Excision of HIV-1 proviral DNA by recombinant cell permeable tre-recombinase. PLoS ONE 7, e31576 (2012).
    • (2012) PLoS ONE , vol.7
    • Mariyanna, L.1
  • 39
    • 78651092348 scopus 로고    scopus 로고
    • A suicide gene approach using the human proapoptotic protein tBid inhibits HIV-1 replication
    • Huelsmann, P.M. et al. A suicide gene approach using the human proapoptotic protein tBid inhibits HIV-1 replication. BMC Biotechnol. 11, 4 (2011).
    • BMC Biotechnol , vol.11 , Issue.4 , pp. 2011
    • Huelsmann, P.M.1
  • 40
    • 16044373004 scopus 로고    scopus 로고
    • Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
    • Samson, M. et al. Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 382, 722-725 (1996).
    • (1996) Nature , vol.382 , pp. 722-725
    • Samson, M.1
  • 41
    • 83155176150 scopus 로고    scopus 로고
    • The effect of the CCR5-delta32 deletion on global gene expression considering immune response and inflammation
    • Hutter, G., Neumann, M., Nowak, D., Klein, S., Kluter, H. & Hofmann, W.K. The effect of the CCR5-delta32 deletion on global gene expression considering immune response and inflammation. J. Inflamm. (Lond). 8, 29 (2011).
    • J. Inflamm. (Lond). , vol.8 , Issue.29 , pp. 2011
    • Hutter, G.1    Neumann, M.2    Nowak, D.3    Klein, S.4    Kluter, H.5    Hofmann, W.K.6
  • 42
    • 27344445600 scopus 로고    scopus 로고
    • CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection
    • Anderson, J. & Akkina, R. CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection. Retrovirology 2, 53 (2005).
    • (2005) Retrovirology , vol.2 , pp. 53
    • Anderson, J.1    Akkina, R.2
  • 43
    • 0032482926 scopus 로고    scopus 로고
    • Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
    • Ma, Q. et al. Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc. Natl. Acad. Sci. USA 95, 9448-9453 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 9448-9453
    • Ma, Q.1
  • 44
    • 0026600926 scopus 로고
    • Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population
    • Schuitemaker, H. et al. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population. J. Virol. 66, 1354-1360 (1992).
    • (1992) J. Virol , vol.66 , pp. 1354-1360
    • Schuitemaker, H.1
  • 45
    • 44649102135 scopus 로고    scopus 로고
    • Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
    • Keele, B.F. et al. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc. Natl. Acad. Sci. USA 105, 7552-7557 (2008).
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 7552-7557
    • Keele, B.F.1
  • 46
    • 0031575431 scopus 로고    scopus 로고
    • Change in coreceptor use correlates with disease progression in HIV-1-infected individuals
    • Connor, R.I., Sheridan, K.E., Ceradini, D., Choe, S. & Landau, N.R. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals. J. Exp. Med. 185, 621-628 (1997).
    • (1997) J. Exp. Med , vol.185 , pp. 621-628
    • Connor, R.I.1    Sheridan, K.E.2    Ceradini, D.3    Choe, S.4    Landau, N.R.5
  • 47
    • 16044367526 scopus 로고    scopus 로고
    • The role of a mutant CCR5 allele in HIV-1 transmission and disease progression
    • Huang, Y. et al. The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat. Med. 2, 1240-1243 (1996).
    • (1996) Nat. Med , vol.2 , pp. 1240-1243
    • Huang, Y.1
  • 48
    • 15844388931 scopus 로고    scopus 로고
    • Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
    • Liu, R. et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86, 367-377 (1996).
    • (1996) Cell , vol.86 , pp. 367-377
    • Liu, R.1
  • 49
    • 0007643930 scopus 로고    scopus 로고
    • Association between CCR5 genotype and the clinical course of HIV-1 infection
    • de Roda Husman, A.M. et al. Association between CCR5 genotype and the clinical course of HIV-1 infection. Ann. Intern. Med. 127, 882-890 (1997).
    • (1997) Ann. Intern. Med , vol.127 , pp. 882-890
    • De Roda Husman, A.M.1
  • 50
    • 79953117041 scopus 로고    scopus 로고
    • Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation
    • Allers, K. et al. Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation. Blood 117, 2791-2799 (2011).
    • (2011) Blood , vol.117 , pp. 2791-2799
    • Allers, K.1
  • 51
    • 60549090253 scopus 로고    scopus 로고
    • Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation
    • Hutter, G. et al. Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation. N. Engl. J. Med. 360, 692-698 (2009).
    • (2009) N. Engl. J. Med , vol.360 , pp. 692-698
    • Hutter, G.1
  • 52
    • 84871326929 scopus 로고    scopus 로고
    • Long-term reduction in peripheral blood HIV-1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation in two HIV-positive individuals XIX
    • Washington, D.C. 22-27 July 2012
    • Henrich, T. J. et al. Long-term reduction in peripheral blood HIV-1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation in two HIV-positive individuals. XIX International AIDS Conference, Washington, DC, 22-27 July 2012
    • International AIDS Conference
    • Henrich, T.J.1
  • 53
    • 46949095221 scopus 로고    scopus 로고
    • Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
    • Perez, E.E. et al. Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases. Nat. Biotechnol. 26, 808-816 (2008).
    • (2008) Nat. Biotechnol , vol.26 , pp. 808-816
    • Perez, E.E.1
  • 54
    • 78650735673 scopus 로고    scopus 로고
    • Human hematopoietic stem/progenitor cells modified by zincfinger nucleases targeted to CCR5 control HIV-1 in vivo
    • Holt, N. et al. Human hematopoietic stem/progenitor cells modified by zincfinger nucleases targeted to CCR5 control HIV-1 in vivo. Nat. Biotechnol. 28, 839-847 (2010).
    • (2010) Nat. Biotechnol , vol.28 , pp. 839-847
    • Holt, N.1
  • 55
    • 84876483018 scopus 로고    scopus 로고
    • Introduction of acquired CCR5 deficiency with zinc finger nuclease-modified autologous CD4 T cells (SB-728-T) correlates with increases in CD4 count and effects on viral load in HIV-infected subjects
    • March 2012
    • June, C. et al. Introduction of acquired CCR5 deficiency with zinc finger nuclease-modified autologous CD4 T cells (SB-728-T) correlates with increases in CD4 count and effects on viral load in HIV-infected subjects. 19th Conference on Retroviruses and Opportunistic Infections, Seattle, WA, 5-8 March 2012
    • 19th Conference on Retroviruses and Opportunistic Infections, Seattle, W.A. , pp. 5-8
    • June, C.1
  • 56
    • 84899423922 scopus 로고    scopus 로고
    • A single infusion of zinc finger nuclease CCR5 modified autologous CD4 T cells (SB-728-T) increases CD4 counts and leads to decrease in HIV proviral load in an aviremic HIV-infected subject
    • Seattle, W.A. March 2012
    • Lalezari, J. et al. A single infusion of zinc finger nuclease CCR5 modified autologous CD4 T cells (SB-728-T) increases CD4 counts and leads to decrease in HIV proviral load in an aviremic HIV-infected subject. 19th Conference on Retroviruses and Opportunistic Infections, Seattle, WA, 5-8 March 2012
    • 19th Conference on Retroviruses and Opportunistic Infections , pp. 5-8
    • Lalezari, J.1
  • 57
    • 33646443202 scopus 로고    scopus 로고
    • Emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants in a minority of HIV-1-infected patients following treatment with the CCR5 antagonist maraviroc is from a pretreatment CXCR4- using virus reservoir
    • Westby, M. et al. Emergence of CXCR4-using human immunodeficiency virus type 1 (HIV-1) variants in a minority of HIV-1-infected patients following treatment with the CCR5 antagonist maraviroc is from a pretreatment CXCR4- using virus reservoir. J. Virol. 80, 4909-4920 (2006).
    • (2006) J. Virol , vol.80 , pp. 4909-4920
    • Westby, M.1
  • 58
    • 79960078119 scopus 로고    scopus 로고
    • Resistance to the CCR5 inhibitor 5P12-RANTES requires a difficult evolution from CCR5 to CXCR4 coreceptor use
    • Nedellec, R., Coetzer, M., Lederman, M.M., Offord, R.E., Hartley, O. & Mosier, D.E. Resistance to the CCR5 inhibitor 5P12-RANTES requires a difficult evolution from CCR5 to CXCR4 coreceptor use. PLoS ONE 6, e22020 (2011).
    • (2011) PLoS ONE , vol.6
    • Nedellec, R.1    Coetzer, M.2    Lederman, M.M.3    Offord, R.E.4    Hartley, O.5    Mosier, D.E.6
  • 59
    • 79955785236 scopus 로고    scopus 로고
    • Engineering HIV-resistant human CD4+ T cells with CXCR4- specific zinc-finger nucleases
    • Wilen, C.B. et al. Engineering HIV-resistant human CD4+ T cells with CXCR4- specific zinc-finger nucleases. PLoS Pathog. 7, e1002020 (2011).
    • (2011) PLoS Pathog , vol.7
    • Wilen, C.B.1
  • 60
    • 84862777608 scopus 로고    scopus 로고
    • Zinc-finger nuclease editing of human CXCR4 promotes HIV-1 CD4(+) T cell resistance and enrichment
    • Y uan, J. et al. Zinc-finger nuclease editing of human CXCR4 promotes HIV-1 CD4(+) T cell resistance and enrichment. Mol. Ther. 20, 849-859 (2012).
    • (2012) Mol. Ther , vol.20 , pp. 849-859
    • Yuan, J.1
  • 61
    • 77955608799 scopus 로고    scopus 로고
    • RNA-based gene therapy for HIV with lentiviral vectormodified CD34(+) cells in patients undergoing transplantation for AIDSrelated lymphoma
    • DiGiusto, D.L. et al. RNA-based gene therapy for HIV with lentiviral vectormodified CD34(+) cells in patients undergoing transplantation for AIDSrelated lymphoma. Sci. Transl. Med. 2, 36ra43 (2010).
    • (2010) Sci. Transl. Med , vol.2
    • DiGiusto, D.L.1
  • 62
    • 79956077563 scopus 로고    scopus 로고
    • T cell exhaustion
    • Wherry, E.J. T cell exhaustion. Nat. Immunol. 12, 492-499 (2011).
    • (2011) Nat. Immunol , vol.12 , pp. 492-499
    • Wherry, E.J.1
  • 63
    • 41649083599 scopus 로고    scopus 로고
    • Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy
    • Palmer, S. et al. Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy. Proc. Natl. Acad. Sci. USA 105, 3879-3884 (2008).
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 3879-3884
    • Palmer, S.1
  • 64
    • 70350322293 scopus 로고    scopus 로고
    • Defective human immunodeficiency virus-specific CD8+T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy
    • Migueles, S.A. et al. Defective human immunodeficiency virus-specific CD8+T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy. J. Virol. 83, 11876-11889 (2009).
    • (2009) J. Virol , vol.83 , pp. 11876-11889
    • Migueles, S.A.1
  • 65
    • 32544459770 scopus 로고    scopus 로고
    • Restoring function in exhausted CD8 T cells during chronic viral infection
    • Barber, D.L. et al. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439, 682-687 (2006).
    • (2006) Nature , vol.439 , pp. 682-687
    • Barber, D.L.1
  • 66
    • 33748947326 scopus 로고    scopus 로고
    • PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
    • Day, C.L. et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443, 350-354 (2006).
    • (2006) Nature , vol.443 , pp. 350-354
    • Day, C.L.1
  • 67
    • 33749009709 scopus 로고    scopus 로고
    • Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
    • Trautmann, L. et al. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat. Med. 12, 1198-1202 (2006).
    • (2006) Nat. Med , vol.12 , pp. 1198-1202
    • Trautmann, L.1
  • 68
    • 34547931898 scopus 로고    scopus 로고
    • SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection
    • Petrovas, C. et al. SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection. Blood 110, 928-936 (2007).
    • (2007) Blood , vol.110 , pp. 928-936
    • Petrovas, C.1
  • 69
    • 60549087784 scopus 로고    scopus 로고
    • PD-1 blockade in rhesus macaques: Impact on chronic infection and prophylactic vaccination
    • Finnefrock, A.C. et al. PD-1 blockade in rhesus macaques: Impact on chronic infection and prophylactic vaccination. J. Immunol. 182, 980-987 (2009).
    • (2009) J. Immunol , vol.182 , pp. 980-987
    • Finnefrock, A.C.1
  • 70
    • 62249172189 scopus 로고    scopus 로고
    • Enhancing SIV-specific immunity in vivo by PD-1 blockade
    • Velu, V. et al. Enhancing SIV-specific immunity in vivo by PD-1 blockade. Nature 458, 206-210 (2009).
    • (2009) Nature , vol.458 , pp. 206-210
    • Velu, V.1
  • 71
    • 49649114804 scopus 로고    scopus 로고
    • Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
    • Berger, R. et al. Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies. Clin. Cancer Res. 14, 3044-3051 (2008).
    • (2008) Clin. Cancer Res , vol.14 , pp. 3044-3051
    • Berger, R.1
  • 72
    • 79957891364 scopus 로고    scopus 로고
    • PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cell/myeloma fusion vaccine
    • Rosenblatt, J. et al. PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cell/myeloma fusion vaccine. J. Immunother. 34, 409-418 (2011).
    • (2011) J. Immunother , vol.34 , pp. 409-418
    • Rosenblatt, J.1
  • 73
    • 84867079698 scopus 로고    scopus 로고
    • PD-1/PD-L1 blockade can enhance HIV-1 Gag-specific t cell immunity elicited by dendritic cell-directed lentiviral vaccines
    • Dai, B., Xiao, L., Bryson, P.D., Fang, J. & Wang, P. PD-1/PD-L1 blockade can enhance HIV-1 Gag-specific t cell immunity elicited by dendritic cell-directed lentiviral vaccines. Mol. Ther. 20,1800-1809 (2012).
    • (2012) Mol. Ther , vol.20 , pp. 1800-1809
    • Dai, B.1    Xiao, L.2    Bryson, P.D.3    Fang, J.4    Wang, P.5
  • 74
    • 77957059176 scopus 로고    scopus 로고
    • Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection
    • Jin, H.T. et al. Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. Proc. Natl. Acad. Sci. USA 107, 14733-14738 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 14733-14738
    • Jin, H.T.1
  • 75
    • 78049401660 scopus 로고    scopus 로고
    • Regulation of virus-specific CD4+ T cell function by multiple costimulatory receptors during chronic HIV infection
    • Kassu, A. et al. Regulation of virus-specific CD4+ T cell function by multiple costimulatory receptors during chronic HIV infection. J. Immunol. 185, 3007-3018 (2010).
    • (2010) J. Immunol , vol.185 , pp. 3007-3018
    • Kassu, A.1


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