Disulfiram reactivates latent HIV-1 expression through depletion of the phosphatase and tensin homolog

AIDS

Volumn 27, Issue 2, 2013, Pages

  Doyon, Geneviève ^a   Zerbato, Jennifer ^a   Mellors, John W ^a   Sluis Cremer, Nicolas ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Akt; disulfiram; HIV 1; latency; phosphatase and tensin homolog

Indexed keywords

DISULFIRAM; I KAPPA B; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN KINASE B INHIBITOR; SMALL INTERFERING RNA;

ARTICLE; CD4+ T LYMPHOCYTE; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; VIRUS LATENCY; VIRUS LOAD; VIRUS REACTIVATION;

CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; DISULFIRAM; ENZYME INHIBITORS; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; MALE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; VIRUS ACTIVATION; VIRUS LATENCY;

EID: 84872393902     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e3283570620     Document Type: Article

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