Lack of the phosphatase PTPN22 increases adhesion of murine regulatory T cells to improve their immunosuppressive function

Science Signaling

Volumn 5, Issue 252, 2012, Pages

  Brownlie, Rebecca J ^a   Miosge, Lisa A ^b,e   Vassilakos, Demetrios ^b,f   Svensson, Lena M ^c,d   Cope, Andrew ^c   Zamoyska, Rose ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d LUND UNIVERSITY   (Sweden)

^e Biology and Environment   (Australia)

^f EPSOM AND ST HELIER UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ADHESION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; IMMUNOREGULATION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION;

ANIMALS; AUTOIMMUNE DISEASES; CELL ADHESION; HUMANS; IMMUNE TOLERANCE; INTEGRINS; INTERLEUKIN-10; MICE; MICE, KNOCKOUT; MUTATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 22; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY;

MURINAE; MUS;

EID: 84870318487     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2003365     Document Type: Article

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