PEST Domain-Enriched Tyrosine Phosphatase (PEP) Regulation of Effector/Memory T Cells

Science

Volumn 303, Issue 5658, 2004, Pages 685-689

  Hasegawa, Kiminori ^a   Martin, Flavius ^a   Huang, Guangming ^a   Tumas, Dan ^a   Diehl, Lauri ^a   Chan, Andrew C ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; ANTIBODIES; ANTIGENS; CELLS;

CELL DEVELOPMENT;

PROTEINS;

PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR;

MEMORY;

ANIMAL CELL; ARTICLE; CELL FUNCTION; CELL MATURATION; CELLULAR IMMUNITY; CONTROLLED STUDY; EFFECTOR CELL; FEMALE; GERMINAL CENTER; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REGULATORY MECHANISM; THYMOCYTE;

ANIMALS; AUTOIMMUNITY; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL CYCLE; GENE TARGETING; GERMINAL CENTER; HYDROGEN-ION CONCENTRATION; IMMUNOGLOBULINS; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES;

ANIMALIA;

EID: 0942279640     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1092138     Document Type: Article

References (29)

1. T. Mustelin, S. Rahmouni, N. Bottini, A. Alonso, Immunol. Rev. 191, 139 (2003).
2. R. J. Matthews, D. B. Bowne, E. Flores, M. L. Thomas, Mol. Cell. Biol. 12, 2396 (1992).
3. J. F. Cloutier, A. Veillette, J. Exp. Med. 189, 111 (1999).
4. J. F. Cloutier, A. Veillette, EMBO J. 15, 4909 (1996).
5. D. Davidson, J. F. Cloutier, A. Gregorieff, A. Veillette, J. Biol. Chem. 272, 23455 (1997).
6. D. Davidson, A. Veillette, EMBO J. 20, 3414 (2001).
7. Materials and methods are available on Science Online.
8. H. S. Azzam et al., J. Exp. Med. 188, 2301 (1998).
9. H. S. Azzam et al., J. Immunol. 166, 5464 (2001).
10. P. Kisielow, H. S. Teh, H. Bluthmann, H. von Boehmer, Nature 335, 730 (1988).
11. K. M. Murphy, A. B. Heimberger, D. Y. Loh, Science 250, 1720 (1990).
12. P. Kislelow, H. Bluthmann, U. D. Staerz, M. Steinmetz, H. von Boehmer, Nature 333, 742 (1988).
13. Y. F. Shi et al., J. Immunol. 146, 3340 (1991).
14. K. Hasegawa, A. C. Chan, data not shown
15. R. W. Dutton, L. M. Bradley, S. L. Swain, Annu. Rev. Immunol. 16, 201 (1998).
16. L. E. Harrington, M. Galvan, L. G. Baum, J. D. Altman, R. Ahmed, J. Exp. Med. 191, 1241 (2000).
17. H. Hu et al., Nature Immunol. 2, 70S (2001).
18. A. Gjorloff-Wingren, M. Saxena, S. Williams, D. Hammi, T. Mustelin, Eur. J. Immunol. 29, 3845 (1999).
19. J. D. Marth et al., Mol. Cell. Biol. 8, S40 (1988).
20. M. Hatakeyama et al., Science 252, 1523 (1991).
21. S. M. Kaech, S. Hemby, E. Kersh, R. Ahmed, Cell 111, 837 (2002).
22. I. G. Luzina et al., J. Leukoc. Biol. 70, S78 (2001).
23. S. T. Ong et al., Oncogene 16, 2333 (1998).
24. S. Bolland, J. V. Ravetch, Immunity 13, 277 (2000).
25. T. L. O'Keefe, G. T. Williams, S. L. Davies, M. S. Neuberger, Science 274, 798 (1996).
26. A. Miyamoto et al., Nature 416, 865 (2002).
27. C. W. Chiu, M. Dalton, M. Ishial, T. Kurosaki, A. C. Chan, EMBO J. 21, 6461 (2002).
28. A. C. Chan et al., J. Immunol. 152, 4758 (1994).
29. We thank W. Ouyang, B. Irving and Chan Lab members for critical suggestions; X. Jin, T. Woodford-Thomas, W. Lee, P. Gribling, Y. Zhang, L. Tom, C. Olsson, J. Starks, M. Fuentes, J. Morales, M. van Hoy, Y. Mehari and L. DeForge for technical assistance; H. Yakura and A. Shaw for reagents. This paper is dedicated to the memory of Matthew L. Thomas.