PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoimmune background

Journal of Immunology

Volumn 182, Issue 7, 2009, Pages 4093-4106

  Zikherman, Julie ^a,b   Hermiston, Michelle ^b   Steiner, David ^a   Hasegawa, Kiminori ^c   Chan, Andrew ^c   Weiss, Arthur ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD45 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; L SELECTIN; LYMPHOCYTE ANTIGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; PROTEIN PEP; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG; PTPN22 PROTEIN, HUMAN; PTPRC PROTEIN, HUMAN;

ALLELE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DISEASE PREDISPOSITION; GENE; GENE LOCUS; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; LEUKEMIA CELL LINE; LUPUS LIKE SYNDROME; LYMPHADENOPATHY; LYMPHOCYTE ACTIVATION; MEMORY T LYMPHOCYTE; MICROENVIRONMENT; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PTPN22 GENE; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; WILD TYPE; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC PREDISPOSITION; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; T LYMPHOCYTE; WESTERN BLOTTING;

ALLELES; ANIMALS; ANTIGENS, CD45; AUTOIMMUNITY; B-LYMPHOCYTES; BLOTTING, WESTERN; CELL DIFFERENTIATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IMMUNE TOLERANCE; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MICE; POLYMORPHISM, GENETIC; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 22; T-LYMPHOCYTES;

EID: 64249119896     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0803317     Document Type: Article

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