-
1
-
-
22144489833
-
Rnai: The nuts and bolts of the risc machine
-
Filipowicz W. RNAi: the nuts and bolts of the RISC machine. Cell. 2005;122:17-20.
-
(2005)
Cell
, vol.122
, pp. 17-12
-
-
Filipowicz, W.1
-
2
-
-
77955644289
-
Mammalian micrornas predominantly act to decrease target mrna levels
-
Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature. 2010;466:835-40.
-
(2010)
Nature
, vol.466
, pp. 835-834
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
Bartel, D.P.4
-
3
-
-
26944441255
-
Dicing and slicing: The core machinery of the rna interference pathway
-
Hammond SM. Dicing and slicing: the core machinery of the RNA interference pathway. FEBS Lett. 2005;579:5822-9.
-
(2005)
FEBS Lett
, vol.579
, pp. 5822-5829
-
-
Hammond, S.M.1
-
4
-
-
0037062951
-
Rna interference
-
Hannon GJ. RNA interference. Nature. 2002;418:244-51.
-
(2002)
Nature
, vol.418
, pp. 244-245
-
-
Hannon, G.J.1
-
7
-
-
0035955361
-
An abundant class of tiny rnas with probable regulatory roles in caenorhabditis elegans
-
Lau NC, Lim LP, Weinstein EG, Bartel DP. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science. 2001;294:858-62.
-
(2001)
Science
, vol.294
, pp. 858-856
-
-
Lau, N.C.1
Lim, L.P.2
Weinstein, E.G.3
Bartel, D.P.4
-
8
-
-
0035955366
-
An extensive class of small rnas in caenorhabditis elegans
-
Lee RC, Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science. 2001;294:862-4.
-
(2001)
Science
, vol.294
, pp. 862-864
-
-
Lee, R.C.1
Ambros, V.2
-
9
-
-
0034597777
-
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory rna
-
Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, Maller B, Hayward DC, Ball EE, Degnan B, Müller P, Spring J, Srinivasan A, Fishman M, Finnerty J, Corbo J, Levine M, Leahy P, Davidson E, Ruvkun G (2000) Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408:86-89.
-
(2000)
Nature
, vol.408
, pp. 86-88
-
-
Pasquinelli, A.E.1
Reinhart, B.J.2
Slack, F.3
Martindale, M.Q.4
Kuroda, M.I.5
Maller, B.6
Hayward, D.C.7
Ball, E.E.8
Degnan, B.9
Müller, P.10
Spring, J.11
Srinivasan, A.12
Fishman, M.13
Finnerty, J.14
Corbo, J.15
Levine, M.16
Leahy, P.17
Davidson, E.18
Ruvkun, G.19
-
10
-
-
20444460289
-
Microrna expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR. MicroRNA expression profiles classify human cancers. Nature. 2005;435:834-8.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
Downing, J.R.11
Jacks, T.12
Horvitz, H.R.13
Golub, T.R.14
-
11
-
-
20444467290
-
A microrna polycistron as a potential human oncogene
-
He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, Goodson S, Powers S, Cordon-Cardo C, Lowe SW, Hannon GJ, Hammond SM. A microRNA polycistron as a potential human oncogene. Nature. 2005;435:828-33.
-
(2005)
Nature
, vol.435
, pp. 828-823
-
-
He, L.1
Thomson, J.M.2
Hemann, M.T.3
Hernando-Monge, E.4
Mu, D.5
Goodson, S.6
Powers, S.7
Cordon-Cardo, C.8
Lowe, S.W.9
Hannon, G.J.10
Hammond, S.M.11
-
12
-
-
27544495514
-
A polycistronic microrna cluster, mir-17-92, is overexpressed in human lung cancers and enhances cell proliferation
-
Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yanagisawa K, Tomida S, Yatabe Y, Kawahara K, Sekido Y, Takahashi T. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res. 2005;65:9628-32.
-
(2005)
Cancer Res
, vol.65
, pp. 9628-9623
-
-
Hayashita, Y.1
Osada, H.2
Tatematsu, Y.3
Yamada, H.4
Yanagisawa, K.5
Tomida, S.6
Yatabe, Y.7
Kawahara, K.8
Sekido, Y.9
Takahashi, T.10
-
13
-
-
44049108170
-
Loss of microrna cluster mir-29a/b-1 in sporadic alzheimer's disease correlates with increased bace1/beta-secretase expression
-
Hébert SS, Horré K, Nicolaï L, Papadopoulou AS, Mandemakers W, Silahtaroglu AN, Kauppinen S, Delacourte A, De Strooper B. Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci USA. 2008;105:6415-20.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 6415-6412
-
-
Hébert, S.S.1
Horré, K.2
Nicolaï, L.3
Papadopoulou, A.S.4
Mandemakers, W.5
Silahtaroglu, A.N.6
Kauppinen, S.7
Delacourte, A.8
De Strooper, B.9
-
14
-
-
56649112767
-
A mirna signature of prion induced neurodegeneration
-
Saba R, Goodman CD, Huzarewich RL, Robertson C, Booth SA (2008) A miRNA signature of prion induced neurodegeneration. PLoS ONE 3e:3652.
-
(2008)
PLoS ONE
, vol.3 E
, pp. 3652
-
-
Saba, R.1
Goodman, C.D.2
Huzarewich, R.L.3
Robertson, C.4
Booth, S.A.5
-
15
-
-
9144270691
-
A pancreatic islet-specific microrna regulates insulin secretion
-
Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M. A pancreatic islet-specific microRNA regulates insulin secretion. Nature. 2004;432:226-30.
-
(2004)
Nature
, vol.432
, pp. 226-223
-
-
Poy, M.N.1
Eliasson, L.2
Krutzfeldt, J.3
Kuwajima, S.4
Ma, X.5
Macdonald, P.E.6
Pfeffer, S.7
Tuschl, T.8
Rajewsky, N.9
Rorsman, P.10
Stoffel, M.11
-
17
-
-
58149350340
-
Alterations in microrna expression contribute to fatty acid-induced pancreatic beta-cell dysfunction
-
Lovis P, Roggli E, Laybutt DR, Gattesco S, Yang JY, Widmann C, Abderrahmani A, Regazzi R. Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction. Diabetes. 2008;57:2728-36.
-
(2008)
Diabetes
, vol.57
, pp. 2728-2723
-
-
Lovis, P.1
Roggli, E.2
Laybutt, D.R.3
Gattesco, S.4
Yang, J.Y.5
Widmann, C.6
Abderrahmani, A.7
Regazzi, R.8
-
18
-
-
2342420041
-
Identification of virus-encoded micrornas
-
Pfeffer S, Zavolan M, Grässer FA, Chien M, Russo JJ, Ju J, John B, Enright AJ, Marks D, Sander C, Tuschl T. Identification of virus-encoded microRNAs. Science. 2004;304:734-6.
-
(2004)
Science
, vol.304
, pp. 734-736
-
-
Pfeffer, S.1
Zavolan, M.2
Grässer, F.A.3
Chien, M.4
Russo, J.J.5
Ju, J.6
John, B.7
Enright, A.J.8
Marks, D.9
Sander, C.10
Tuschl, T.11
-
19
-
-
20844463414
-
Identification of micrornas of the herpesvirus family
-
Pfeffer S, Sewer A, Lagos-Quintana M, Sheridan R, Sander C, Grässer FA, van Dyk LF, Ho CK, Shuman S, Chien M, Russo JJ, Ju J, Randall G, Lindenbach BD, Rice CM, Simon V, Ho DD, Zavolan M, Tuschl T. Identification of microRNAs of the herpesvirus family. Nat Methods. 2005;2:269-76.
-
(2005)
Nat Methods
, vol.2
, pp. 269-267
-
-
Pfeffer, S.1
Sewer, A.2
Lagos-Quintana, M.3
Sheridan, R.4
Sander, C.5
Grässer, F.A.6
Van Dyk, L.F.7
Ho, C.K.8
Shuman, S.9
Chien, M.10
Russo, J.J.11
Ju, J.12
Randall, G.13
Lindenbach, B.D.14
Rice, C.M.15
Simon, V.16
Ho, D.D.17
Zavolan, M.18
Tuschl, T.19
-
20
-
-
63649146590
-
Cellular versus viral micrornas in host-virus interaction
-
Ghosh Z,Mallick B, Chakrabarti J.Cellular versus viral microRNAs in host-virus interaction. Nucleic Acids Res. 2009;37:1035-48.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1035-1034
-
-
Ghosh, Z.1
Mallick, B.2
Chakrabarti, J.3
-
21
-
-
33847038668
-
Micrornas play an essential role in the development of cardiac hypertrophy
-
Sayed D, Hong C, Chen IY, Lypowy J, Abdellatif M. MicroRNAs play an essential role in the development of cardiac hypertrophy. Circ Res. 2007;100:416-24.
-
(2007)
Circ Res
, vol.100
, pp. 416-412
-
-
Sayed, D.1
Hong, C.2
Chen, I.Y.3
Lypowy, J.4
Abdellatif, M.5
-
22
-
-
57749168828
-
Microrna-21 contributes to myocardial disease by stimulating map kinase signalling in fibroblasts
-
Thum T, Gross C, Fiedler J, Fischer T, Kissler S, Bussen M, Galuppo P, Just S, Rottbauer W, Frantz S, Castoldi M, Soutschek J, Koteliansky V, Rosenwald A, Basson MA, Licht JD, Pena JT, Rouhanifard SH, Muckenthaler MU, Tuschl T, Martin GR, Bauersachs J, Engelhardt S. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature. 2008;456:980-4.
-
(2008)
Nature
, vol.456
, pp. 980-984
-
-
Thum, T.1
Gross, C.2
Fiedler, J.3
Fischer, T.4
Kissler, S.5
Bussen, M.6
Galuppo, P.7
Just, S.8
Rottbauer, W.9
Frantz, S.10
Castoldi, M.11
Soutschek, J.12
Koteliansky, V.13
Rosenwald, A.14
Basson, M.A.15
Licht, J.D.16
Pena, J.T.17
Rouhanifard, S.H.18
Muckenthaler, M.U.19
Tuschl, T.20
Martin, G.R.21
Bauersachs, J.22
Engelhardt, S.23
more..
-
23
-
-
56649105278
-
Microrna-138 modulates cardiac patterning during embryonic development
-
Morton SU, Scherz PJ, Cordes KR, Ivey KN, Stainier DY, Srivastava D. microRNA-138 modulates cardiac patterning during embryonic development. Proc Natl Acad Sci USA. 2008;105: 17830-5.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 17830-17835
-
-
Morton, S.U.1
Scherz, P.J.2
Cordes, K.R.3
Ivey, K.N.4
Stainier, D.Y.5
Srivastava, D.6
-
24
-
-
35348992063
-
Allele-specific targeting of micrornas to hla-g and risk of asthma
-
Tan Z, Randall G, Fan J, Camoretti-Mercado B, Brockman-Schneider R, Pan L, Solway J, Gern JE, Lemanske RF, Nicolae D, Ober C. Allele-specific targeting of microRNAs to HLA-G and risk of asthma. Am J Hum Genet. 2007;81:829-34.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 829-823
-
-
Tan, Z.1
Randall, G.2
Fan, J.3
Camoretti-Mercado, B.4
Brockman-Schneider, R.5
Pan, L.6
Solway, J.7
Gern, J.E.8
Lemanske, R.F.9
Nicolae, D.10
Ober, C.11
-
25
-
-
42449156220
-
Altered expression of microrna in synovial fibroblasts and synovial tissue in rheumatoid arthritis
-
Stanczyk J, Pedrioli DM, Brentano F, Sanchez-Pernaute O, Kolling C, Gay RE, Detmar M, Gay S, Kyburz D. Altered expression of microRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum. 2008;58:1001-9.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1001-1009
-
-
Stanczyk, J.1
Pedrioli, D.M.2
Brentano, F.3
Sanchez-Pernaute, O.4
Kolling, C.5
Gay, R.E.6
Detmar, M.7
Gay, S.8
Kyburz, D.9
-
26
-
-
43949136123
-
Expression of microrna-146 in rheumatoid arthritis synovial tissue
-
Nakasa T, Miyaki S, Okubo A, Hashimoto M, Nishida K, Ochi M, Asahara H. Expression of microRNA-146 in rheumatoid arthritis synovial tissue. Arthritis Rheum. 2008;58:1284-92.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1284-1289
-
-
Nakasa, T.1
Miyaki, S.2
Okubo, A.3
Hashimoto, M.4
Nishida, K.5
Ochi, M.6
Asahara, H.7
-
27
-
-
37849031502
-
Microarray analysis of microrna expression in peripheral blood cells of systemic lupus erythematosus patients
-
Dai Y, Huang YS, Tang M, Lv TY, Hu CX, Tan YH, Xu ZM, Yin YB. Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients. Lupus. 2007; 16:939-46.
-
(2007)
Lupus
, vol.16
, pp. 939-934
-
-
Dai, Y.1
Huang, Y.S.2
Tang, M.3
Lv, T.Y.4
Hu, C.X.5
Tan, Y.H.6
Xu, Z.M.7
Yin, Y.B.8
-
28
-
-
69449103973
-
Microrna-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses
-
Miyaki S, Nakasa T, Otsuki S, Grogan SP, Higashiyama R, Inoue A, et al. MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses. Arthritis Rheum. 2009;60:2723-30.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2723-2723
-
-
Miyaki, S.1
Nakasa, T.2
Otsuki, S.3
Grogan, S.P.4
Higashiyama, R.5
Inoue, A.6
-
29
-
-
79551655444
-
Altered expression of microrna-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation
-
Stanczyk J, Ospelt C, Karouzakis E, Filer A, Raza K, Kolling C, et al. Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis Rheum. 2011;63:373-81.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 373-378
-
-
Stanczyk, J.1
Ospelt, C.2
Karouzakis, E.3
Filer, A.4
Raza, K.5
Kolling, C.6
-
30
-
-
8144225486
-
Microrna genes are transcribed by rna polymerase ii
-
Lee Y, Kim M, Han J, Yeom KH, Lee S, Baek SH, Kim VN. MicroRNA genes are transcribed by RNA polymerase II. EMBO J. 2004;23:4051-60.
-
(2004)
EMBO J
, vol.23
, pp. 4051-4056
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.H.4
Lee, S.5
Baek, S.H.6
Kim, V.N.7
-
31
-
-
0141843656
-
The nuclear rnase iii drosha initiates microrna processing
-
Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, Lee J, Provost P, Ra°dmark O, Kim S, Kim VN. The nuclear RNase III Drosha initiates microRNA processing. Nature. 2003;425:415-9.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
Kim, V.N.11
-
32
-
-
1642499415
-
Exportin 5 is a rangtpdependent dsrna-binding protein that mediates nuclear export of pre-mirnas
-
Bohnsack MT, Czaplinski K, Gorlich D. Exportin 5 is a RanGTPdependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA. 2004;10:185-91.
-
(2004)
RNA
, vol.10
, pp. 185-189
-
-
Bohnsack, M.T.1
Czaplinski, K.2
Gorlich, D.3
-
33
-
-
0037033792
-
Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded rna binding proteins
-
Brownawell AM, Macara IG. Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins. J Cell Biol. 2002;156:53-64.
-
(2002)
J Cell Biol
, vol.156
, pp. 53-56
-
-
Brownawell, A.M.1
Macara, I.G.2
-
34
-
-
0347988235
-
Nuclear export of microrna precursors
-
Lund E, Güttinger S, Calado A, Dahlberg JE, Kutay U. Nuclear export of microRNA precursors. Science. 2004;303:95-8.
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Güttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
35
-
-
33750214650
-
Exportin-5 orthologues are functionally divergent among species
-
Shibata S, Sasaki M, Miki T, Shimamoto A, Furuichi Y, Katahira J, Yoneda Y. Exportin-5 orthologues are functionally divergent among species. Nucleic Acids Res. 2006;34:4711-21.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 4711-4712
-
-
Shibata, S.1
Sasaki, M.2
Miki, T.3
Shimamoto, A.4
Furuichi, Y.5
Katahira, J.6
Yoneda, Y.7
-
36
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-micrornas and short hairpin rnas
-
Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 2003;17:3011-6.
-
(2003)
Genes Dev
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
Cullen, B.R.4
-
38
-
-
0035887005
-
Dicer functions in rna interference and in synthesis of small rna involved in developmental timing in c. Elegans
-
Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, Plasterk RH. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 2001;15:2654-9.
-
(2001)
Genes Dev
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
Fischer, S.E.2
Bernstein, E.3
Sijen, T.4
Hannon, G.J.5
Plasterk, R.H.6
-
39
-
-
34447107760
-
The mirtron pathway generates microrna-class regulatory rnas in drosophila
-
Okamura K, Hagen JW, Duan H, Tyler DM, Lai EC. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell. 2007;130:89-100.
-
(2007)
Cell
, vol.130
, pp. 89-81
-
-
Okamura, K.1
Hagen, J.W.2
Duan, H.3
Tyler, D.M.4
Lai, E.C.5
-
40
-
-
35348933779
-
Mammalian mirtron genes
-
Berezikov E, Chung WJ, Willis J, Cuppen E, Lai EC. Mammalian mirtron genes. Mol Cell. 2007;28:328-36.
-
(2007)
Mol Cell
, vol.28
, pp. 328-323
-
-
Berezikov, E.1
Chung, W.J.2
Willis, J.3
Cuppen, E.4
Lai, E.C.5
-
41
-
-
77953183812
-
A dicerindependent mirna biogenesis pathway that requires ago catalysis
-
Cheloufi S, Dos Santos CO, Chong MM, Hannon GJ. A dicerindependent miRNA biogenesis pathway that requires Ago catalysis. Nature. 2010;465:584-9.
-
(2010)
Nature
, vol.465
, pp. 584-589
-
-
Cheloufi, S.1
Dos Santos, C.O.2
Chong, M.M.3
Hannon, G.J.4
-
42
-
-
33750366095
-
Argonaute: A scaffold for the function of short regulatory rnas
-
Parker JS, Barford D. Argonaute: a scaffold for the function of short regulatory RNAs. Trends Biochem Sci. 2006;31:622-30.
-
(2006)
Trends Biochem Sci
, vol.31
, pp. 622-623
-
-
Parker, J.S.1
Barford, D.2
-
43
-
-
13944282215
-
Microarray analysis shows that some micrornas downregulate large numbers of target mrnas
-
Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature. 2005;433:769-73.
-
(2005)
Nature
, vol.433
, pp. 769-767
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
Grimson, A.4
Schelter, J.M.5
Castle, J.6
Bartel, D.P.7
Linsley, P.S.8
Johnson, J.M.9
-
44
-
-
33750370444
-
Microrna signatures in human cancers
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer. 2006;6:857-66.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-856
-
-
Calin, G.A.1
Croce, C.M.2
-
45
-
-
0347444723
-
Micrornas: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116:281-97.
-
(2004)
Cell
, vol.116
, pp. 281-289
-
-
Bartel, D.P.1
-
46
-
-
29144505309
-
The widespread impact of mammalian micrornas on mrna repression and evolution
-
Farh KK, et al. The widespread impact of mammalian microRNAs on mRNA repression and evolution. Science. 2005;310: 1817-21.
-
(2005)
Science
, vol.310
, pp. 1817-1812
-
-
Farh, K.K.1
-
47
-
-
34147153781
-
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking mirna-1-2
-
Zhao Y, et al. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell. 2007;129:303-17.
-
(2007)
Cell
, vol.129
, pp. 303-301
-
-
Zhao, Y.1
-
48
-
-
34247589595
-
Control of stress-dependent cardiac growth and gene expression by a microrna
-
van Rooij E, et al. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science. 2007;316:575-9.
-
(2007)
Science
, vol.316
, pp. 575-579
-
-
Van Rooij, E.1
-
49
-
-
34247594818
-
Regulation of the germinal center response by microrna-155
-
Thai TH, et al. Regulation of the germinal center response by microRNA-155. Science. 2007;316:604-8.
-
(2007)
Science
, vol.316
, pp. 604-608
-
-
Thai, T.H.1
-
50
-
-
34247584465
-
Requirement of bic/microrna-155 for normal immune function
-
Rodriguez A, et al. Requirement of bic/microRNA-155 for normal immune function. Science. 2007;316:608-11.
-
(2007)
Science
, vol.316
, pp. 608-601
-
-
Rodriguez, A.1
-
51
-
-
17644363376
-
A cellular microrna mediates antiviral defense in human cells
-
Lecellier CH, et al. A cellular microRNA mediates antiviral defense in human cells. Science. 2005;308:557-60.
-
(2005)
Science
, vol.308
, pp. 557-556
-
-
Lecellier, C.H.1
-
52
-
-
26844498125
-
Sequence variants in slitrk1 are associated with tourette's syndrome
-
Abelson JF, et al. Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science. 2005;310:317-20.
-
(2005)
Science
, vol.310
, pp. 317-312
-
-
Abelson, J.F.1
-
53
-
-
4143142117
-
Microrna profiling reveals distinct signatures in b cell chronic lymphocytic leukemias
-
Calin GA, et al. MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci USA. 2004;101:11755-60.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 11755-11756
-
-
Calin, G.A.1
-
54
-
-
18744396337
-
Frequent deletions and down-regulation of micro-rna genes mir15 and mir16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA. 2002;99:15524-9.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
-
55
-
-
25444520537
-
Mir-15 and mir-16 induce apoptosis by targeting bcl2
-
Cimmino A, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA. 2005;102:13944-9.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13944-13949
-
-
Cimmino, A.1
-
56
-
-
33748302836
-
Augmentation of tumor angiogenesis by a mycactivated microrna cluster
-
Dews M, et al. Augmentation of tumor angiogenesis by a Mycactivated microRNA cluster. Nat Genet. 2006;38:1060-5.
-
(2006)
Nat Genet
, vol.38
, pp. 1060-1065
-
-
Dews, M.1
-
57
-
-
33646056975
-
A genetic screen implicates mirna-372 and mirna-373 as oncogenes in testicular germ cell tumors
-
Voorhoeve PM, et al. A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell. 2006;124:1169-81.
-
(2006)
Cell
, vol.124
, pp. 1169-1168
-
-
Voorhoeve, P.M.1
-
58
-
-
34249851499
-
Mir-150, a microrna expressed in mature b and t cells, blocks early b cell development when expressed prematurely
-
Zhou B, et al. miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely. Proc Natl Acad Sci USA. 2007;104:7080-5.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7080-7085
-
-
Zhou, B.1
-
59
-
-
33747608638
-
Nf-kappab-dependent induction of microrna mir-146, an inhibitor targeted to signaling proteins of innate immune responses
-
Taganov KD, et al. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA. 2006;103:12481-6.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 12481-12486
-
-
Taganov, K.D.1
-
60
-
-
77956632634
-
Function of mir-146a in controlling treg cellmediated regulation of th1 responses
-
Lu LF, et al. Function of miR-146a in controlling Treg cellmediated regulation of Th1 responses. Cell. 2010;142:914-29.
-
(2010)
Cell
, vol.142
, pp. 914-912
-
-
Lu, L.F.1
-
61
-
-
65249191384
-
Expression of microrna-146a in osteoarthritis cartilage
-
Yamasaki K, et al. Expression of microRNA-146a in osteoarthritis cartilage. Arthritis Rheum. 2009;60:1035-41.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1035-1034
-
-
Yamasaki, K.1
-
62
-
-
34147095310
-
The muscle-specific microrna mir-1 regulates cardiac arrhythmogenic potential by targeting gja1 and kcnj2
-
Yang B, et al. The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat Med. 2007;13:486-91.
-
(2007)
Nat Med
, vol.13
, pp. 486-489
-
-
Yang, B.1
-
63
-
-
34249279050
-
Microrna-133 controls cardiac hypertrophy
-
Care A, et al. MicroRNA-133 controls cardiac hypertrophy. Nat Med. 2007;13:613-8.
-
(2007)
Nat Med
, vol.13
, pp. 613-618
-
-
Care, A.1
-
64
-
-
77953067173
-
Microrna-140 plays dual roles in both cartilage development and homeostasis
-
Miyaki S, Sato T, Inoue A, Otsuki S, Ito Y, Yokoyama S, et al. MicroRNA-140 plays dual roles in both cartilage development and homeostasis. Genes Dev. 2010;24:1173-85.
-
(2010)
Genes Dev
, vol.24
, pp. 1173-1178
-
-
Miyaki, S.1
Sato, T.2
Inoue, A.3
Otsuki, S.4
Ito, Y.5
Yokoyama, S.6
-
65
-
-
39549110203
-
Microrna detection by northern blotting using locked nucleic acid probes
-
Várallyay E, Burgyán J, Havelda Z. MicroRNA detection by northern blotting using locked nucleic acid probes. Nat Protoc. 2008;3:190-6.
-
(2008)
Nat Protoc
, vol.3
, pp. 190-196
-
-
Várallyay, E.1
Burgyán, J.2
Havelda, Z.3
-
66
-
-
16544365954
-
Sensitive and specific detection of micrornas by northern blot analysis using lna-modified oligonucleotide probes
-
Va'lo'czi A, Hornyik C, Varga N, Burgya'n J, Kauppinen S, Havelda Z. Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes. Nucleic Acids Res. 2004;32:e175.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Va'lo'czi, A.1
Hornyik, C.2
Varga, N.3
Burgya'n, J.4
Kauppinen, S.5
Havelda, Z.6
-
67
-
-
79961132803
-
Quantitative stem-loop rt-pcr for detection of micrornas
-
Varkonyi-Gasic E, Hellens RP. Quantitative stem-loop RT-PCR for detection of microRNAs. Methods Mol Biol. 2011;744: 145-57.
-
(2011)
Methods Mol Biol
, vol.744
, pp. 145-145
-
-
Varkonyi-Gasic, E.1
Hellens, R.P.2
-
68
-
-
33750246178
-
Mouse microrna profiles determined with a new and sensitive cloning method
-
Takada S, Berezikov E, Yamashita Y, Lagos-Quintana M, Kloosterman WP, Enomoto M, Hatanaka H, Fujiwara S, Watanabe H, Soda M, Choi YL, Plasterk RH, Cuppen E, Mano H. Mouse microRNA profiles determined with a new and sensitive cloning method. Nucleic Acids Res. 2006;34:e115.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Takada, S.1
Berezikov, E.2
Yamashita, Y.3
Lagos-Quintana, M.4
Kloosterman, W.P.5
Enomoto, M.6
Hatanaka, H.7
Fujiwara, S.8
Watanabe, H.9
Soda, M.10
Choi, Y.L.11
Plasterk, R.H.12
Cuppen, E.13
Mano, H.14
-
69
-
-
39149098467
-
Profiling of microrna expression by mrap
-
Takada S, Mano H. Profiling of microRNA expression by mRAP. Nat Protoc. 2007;2:3136-45.
-
(2007)
Nat Protoc
, vol.2
, pp. 3136-3134
-
-
Takada, S.1
Mano, H.2
-
70
-
-
34548691000
-
Mrap, a sensitive method for determination of microrna expression profiles
-
Mano H, Takada S. mRAP, a sensitive method for determination of microRNA expression profiles. Methods. 2007;3:118-22.
-
(2007)
Methods
, vol.3
, pp. 118-112
-
-
Mano, H.1
Takada, S.2
-
71
-
-
31344454565
-
In situ detection of mirnas in animal embryos using lna-modified oligonucleotide probes
-
Kloosterman WP, Wienholds E, de Bruijn E, Kauppinen S, Plasterk RH. In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes. Nat Methods. 2006; 3:27-9.
-
(2006)
Nat Methods
, vol.3
, pp. 27-29
-
-
Kloosterman, W.P.1
Wienholds, E.2
De Bruijn, E.3
Kauppinen, S.4
Plasterk, R.H.5
-
72
-
-
6944246368
-
Micrornaresponsive 'sensor' transgenes uncover hox-like and other developmentally regulated patterns of vertebrate microrna expression
-
Mansfield JH, Harfe BD, Nissen R, Obenauer J, Srineel J, Chaudhuri A, Farzan-Kashani R, Zuker M, Pasquinelli AE, Ruvkun G, Sharp PA, Tabin CJ, McManus MT. MicroRNAresponsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet. 2004;36:1079-83.
-
(2004)
Nat Genet
, vol.36
, pp. 1079-1078
-
-
Mansfield, J.H.1
Harfe, B.D.2
Nissen, R.3
Obenauer, J.4
Srineel, J.5
Chaudhuri, A.6
Farzan-Kashani, R.7
Zuker, M.8
Pasquinelli, A.E.9
Ruvkun, G.10
Sharp, P.A.11
Tabin, C.J.12
McManus, M.T.13
-
73
-
-
20944450160
-
Combinatorial microrna target predictions
-
Krek A, Grün D, Poy MN, Wolf R, Rosenberg L, Epstein EJ, MacMenamin P, da Piedade I, Gunsalus KC, Stoffel M, Rajewsky N. Combinatorial microRNA target predictions. Nat Genet. 2005;37:495-500.
-
(2005)
Nat Genet
, vol.37
, pp. 495-495
-
-
Krek, A.1
Grün, D.2
Poy, M.N.3
Wolf, R.4
Rosenberg, L.5
Epstein, E.J.6
MacMenamin, P.7
Da Piedade, I.8
Gunsalus, K.C.9
Stoffel, M.10
Rajewsky, N.11
-
74
-
-
0346094457
-
Prediction of mammalian microrna targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB. Prediction of mammalian microRNA targets. Cell. 2003;115: 787-98.
-
(2003)
Cell
, vol.115
, pp. 787-789
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
Bartel, D.P.4
Burge, C.B.5
-
75
-
-
0842321501
-
Microrna targets in drosophila
-
Enright AJ, John B, Gaul U, Tuschl T, Sander C, Marks DS. MicroRNA targets in Drosophila. Genome Biol. 2003;5:R1.
-
(2003)
Genome Biol
, vol.5
-
-
Enright, A.J.1
John, B.2
Gaul, U.3
Tuschl, T.4
Sander, C.5
Marks, D.S.6
-
77
-
-
34748821761
-
The role of site accessibility in microrna target recognition
-
Kertesz M, Iovino N, Unnerstall U, Gaul U, Segal E. The role of site accessibility in microRNA target recognition. Nat Genet. 2007;39:1278-84.
-
(2007)
Nat Genet
, vol.39
, pp. 1278-1278
-
-
Kertesz, M.1
Iovino, N.2
Unnerstall, U.3
Gaul, U.4
Segal, E.5
-
78
-
-
56549105330
-
Hits-clip yields genome-wide insights into brain alternative rna processing
-
Licatalosi DD, Mele A, Fak JJ, Ule J, Kayikci M, Chi SW, Clark TA, Schweitzer AC, Blume JE, Wang X, Darnell JC, Darnell RB. HITS-CLIP yields genome-wide insights into brain alternative RNA processing. Nature. 2008;456:464-9.
-
(2008)
Nature
, vol.456
, pp. 464-469
-
-
Licatalosi, D.D.1
Mele, A.2
Fak, J.J.3
Ule, J.4
Kayikci, M.5
Chi, S.W.6
Clark, T.A.7
Schweitzer, A.C.8
Blume, J.E.9
Wang, X.10
Darnell, J.C.11
Darnell, R.B.12
-
79
-
-
67749132423
-
Argonaute hits-clip decodes microrna-mrna interaction maps
-
Chi SW, Zang JB, Mele A, Darnell RB. Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature. 2009;460: 479-86.
-
(2009)
Nature
, vol.460
, pp. 479-478
-
-
Chi, S.W.1
Zang, J.B.2
Mele, A.3
Darnell, R.B.4
-
80
-
-
33845329203
-
Functional and quantitative proteomics using silac
-
Mann M. Functional and quantitative proteomics using SILAC. Nat Rev Mol Cell Biol. 2006;7:952-8.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 952-958
-
-
Mann, M.1
-
81
-
-
0036583926
-
Stable isotope labeling by amino acids in cell culture, silac, as a simple and accurate approach to expression proteomics
-
Ong SE, Blagoev B, Kratchmarova I, Kristensen DB, Steen H, Pandey A, Mann M. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics. 2002;1:376-86.
-
(2002)
Mol Cell Proteomics
, vol.1
, pp. 376-378
-
-
Ong, S.E.1
Blagoev, B.2
Kratchmarova, I.3
Kristensen, D.B.4
Steen, H.5
Pandey, A.6
Mann, M.7
-
82
-
-
49949117302
-
Widespread changes in protein synthesis induced by micrornas
-
Selbach M, Schwanhäusser B, Thierfelder N, Fang Z, Khanin R, Rajewsky N. Widespread changes in protein synthesis induced by microRNAs. Nature. 2008;455:58-63.
-
(2008)
Nature
, vol.455
, pp. 58-56
-
-
Selbach, M.1
Schwanhäusser, B.2
Thierfelder, N.3
Fang, Z.4
Khanin, R.5
Rajewsky, N.6
-
83
-
-
49949116902
-
The impact of micrornas on protein output
-
Baek D, Villéén J, Shin C, Camargo FD, Gygi SP, Bartel DP. The impact of microRNAs on protein output. Nature. 2008;455:64-71.
-
(2008)
Nature
, vol.455
, pp. 64-67
-
-
Baek, D.1
Villéén, J.2
Shin, C.3
Camargo, F.D.4
Gygi, S.P.5
Bartel, D.P.6
-
84
-
-
28444469246
-
Silencing of micrornas in vivo with antagomirs
-
Krützfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, Stoffel M. Silencing of microRNAs in vivo with 'antagomirs'. Nature. 2005;438:685-9.
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krützfeldt, J.1
Rajewsky, N.2
Braich, R.3
Rajeev, K.G.4
Tuschl, T.5
Manoharan, M.6
Stoffel, M.7
-
85
-
-
14344257055
-
Micrornas as regulators of mammalian hematopoiesis
-
Chen CZ, Lodish HF. MicroRNAs as regulators of mammalian hematopoiesis. Semin Immunol. 2005;17:155-65.
-
(2005)
Semin Immunol
, vol.17
, pp. 155-156
-
-
Chen, C.Z.1
Lodish, H.F.2
-
86
-
-
0035800521
-
A cellular function for the rna-interference enzyme dicer in the maturation of the let-7 small temporal rna
-
Hutvágner G, McLachlan J, Pasquinelli AE, Bálint E, Tuschl T, Zamore PD. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science. 2001;293:834-8.
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvágner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Bálint, E.4
Tuschl, T.5
Zamore, P.D.6
-
87
-
-
1242318826
-
Sequence-specific inhibition of microrna-And sirna-induced rna silencing
-
Meister G, Landthaler M, Dorsett Y, Tuschl T. Sequence-specific inhibition of microRNA-And siRNA-induced RNA silencing. RNA. 2004;10:544-50.
-
(2004)
RNA
, vol.10
, pp. 544-545
-
-
Meister, G.1
Landthaler, M.2
Dorsett, Y.3
Tuschl, T.4
-
88
-
-
22444437609
-
Serum response factor regulates a muscle-specific microrna that targets hand2 during cardiogenesis
-
Zhao Y, Samal E, Srivastava D. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature. 2005;436:214-20.
-
(2005)
Nature
, vol.436
, pp. 214-212
-
-
Zhao, Y.1
Samal, E.2
Srivastava, D.3
-
89
-
-
42249093319
-
Lna-mediated microrna silencing in non-human primates
-
Elmén J, Lindow M, Schütz S, Lawrence M, Petri A, Obad S, Lindholm M, Hedtjärn M, Hansen HF, Berger U, Gullans S, Kearney P, Sarnow P, Straarup EM, Kauppinen S. LNA-mediated microRNA silencing in non-human primates. Nature. 2008;452: 896-9.
-
(2008)
Nature
, vol.452
, pp. 896-899
-
-
Elmén, J.1
Lindow, M.2
Schütz, S.3
Lawrence, M.4
Petri, A.5
Obad, S.6
Lindholm, M.7
Hedtjärn, M.8
Hansen, H.F.9
Berger, U.10
Gullans, S.11
Kearney, P.12
Sarnow, P.13
Straarup, E.M.14
Kauppinen, S.15
-
90
-
-
23344439006
-
The rnaseiii enzyme dicer is required for morphogenesis but not patterning of the vertebrate limb
-
Harfe BD, McManus MT, Mansfield JH, Hornstein E, Tabin CJ. The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc Natl Acad Sci USA. 2005;102:10898-903.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10898-10899
-
-
Harfe, B.D.1
McManus, M.T.2
Mansfield, J.H.3
Hornstein, E.4
Tabin, C.J.5
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