BMP4-Smad signaling pathway mediates adriamycin-induced premature senescence in lung cancer cells

Journal of Biological Chemistry

Volumn 284, Issue 18, 2009, Pages 12153-12164

  Su, Dongmei ^a   Zhu, Shan ^a   Han, Xuefang ^a   Feng, Yunpeng ^a   Huang, Hui ^a   Ren, Guoling ^a   Pan, Lina ^a   Zhang, Yu ^a   Lu, Jun ^a   Huang, Baiqu ^a,b  

^a NORTHEAST NORMAL UNIVERSITY   (China)

^b NONE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADRIAMYCIN; CANCER CHEMOTHERAPY; CELL-CYCLE ARREST; CHEMOTHERAPEUTIC AGENTS; HYPERACETYLATION; LUNG CANCER CELLS; MOLECULAR TARGETS; NON SMALL CELL LUNG CANCER; OVER-EXPRESSION; SMAD SIGNALING; TUMOR CELLS; UP-REGULATION;

BIOLOGICAL ORGANS; CELL PROLIFERATION; CHEMOTHERAPY; SIGNALING;

CELL MEMBRANES;

BONE MORPHOGENETIC PROTEIN 4; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLINE; DOXORUBICIN; HISTONE H3; HISTONE H4; PROTEIN P300; SMAD PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; ANTINEOPLASTIC ANTIBIOTIC; BMP4 PROTEIN, HUMAN; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; HISTONE;

ACETYLATION; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; LUNG CANCER; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SENESCENCE; SIGNAL TRANSDUCTION; UPREGULATION; CELL AGING; DIET THERAPY; DRUG EFFECT; GENETICS; LUNG NON SMALL CELL CANCER; LUNG TUMOR; METABOLISM; TUMOR CELL LINE;

ACETYLATION; ANTIBIOTICS, ANTINEOPLASTIC; BONE MORPHOGENETIC PROTEIN 4; CARCINOMA, NON-SMALL-CELL LUNG; CELL AGING; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOXORUBICIN; HISTONES; HUMANS; LUNG NEOPLASMS; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; SMAD PROTEINS;

EID: 66449087481     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807930200     Document Type: Article

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