Erratum: ERK1/2 Signaling Plays an Important Role in Topoisomerase II Poison-Induced G2/M Checkpoint Activation (PLoS ONE (2012) 7:11 (e50281) DOI: 10.1371/journal.pone.0050281);ERK1/2 Signaling Plays an Important Role in Topoisomerase II Poison-Induced G2/M Checkpoint Activation

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Kolb, Ryan H ^a   Greer, Patrick M ^a   Cao, Phu T ^a   Cowan, Kenneth H ^a   Yan, Ying ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATR PROTEIN; CHECKPOINT KINASE 1; DNA TOPOISOMERASE (ATP HYDROLYSING); MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; POISON; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TOPOISOMERASE II POISON; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL; CELL CYCLE ARREST; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 84869206966     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0292423     Document Type: Erratum

References (80)

1. van Gijn R, Lendfers R, Schellens J, Bult A, Beijnen J, (2000) Dual topoisomerase I/II inhibitors. Journal of Oncology Pharmacy Practice 6: 92-108.
2. Nitiss JL, (2009) Targeting DNA topoisomerase II in cancer chemotherapy. Nat Rev Cancer 9: 338-350.
3. Potter AJ, Rabinovitch PS, (2005) The cell cycle phases of DNA damage and repair initiated by topoisomerase II-targeting chemotherapeutic drugs. Mutat Res 572: 27-44.
4. Kim HS, Lee YS, Kim DK, (2009) Doxorubicin exerts cytotoxic effects through cell cycle arrest and Fas-mediated cell death. Pharmacology 84: 300-309.
5. Baldwin EL, Osheroff N, (2005) Etoposide, topoisomerase II and cancer. Curr Med Chem Anticancer Agents 5: 363-372.
6. Lee TK, Lau TC, Ng IO, (2002) Doxorubicin-induced apoptosis and chemosensitivity in hepatoma cell lines. Cancer Chemother Pharmacol 49: 78-86.
7. Jin Z-H, Kurosu T, Yamaguchi M, Arai A, Miura O, (2005) Hematopoietic cytokines enhance Chk1-dependent G2//M checkpoint activation by etoposide through the Akt//GSK3 pathway to inhibit apoptosis. Oncogene 24: 1973-1981.
8. Jiang H, (2005) Cdk5 activator - binding protein C53 regulates apoptosis induced by genotoxic stress via modulating the G2/M DNA damage checkpoint. Journal of Biological Chemistry 280: 20651-20659.
9. Lin YC, Wang FF, (2008) Mechanisms underlying the pro-survival pathway of p53 in suppressing mitotic death induced by adriamycin. Cell Signal 20: 258-267.
10. Bucher N, (2008) G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer. British journal of cancer 98: 523-528.
11. Montecucco A, Biamonti G, (2007) Cellular response to etoposide treatment. Cancer Lett 252: 9-18.
12. Smits VA, Medema RH, (2001) Checking out the G(2)/M transition. Biochim Biophys Acta 1519: 1-12.
13. Rhind N, Furnari B, Russell P, (1997) Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast. Genes Dev 11: 504-511.
14. Kharbanda S, Saleem A, Datta R, Yuan ZM, Weichselbaum R, et al. (1994) Ionizing radiation induces rapid tyrosine phosphorylation of p34cdc2. Cancer Res 54: 1412-1414.
15. O'Connell MJ, Raleigh JM, Verkade HM, Nurse P, (1997) Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation. Embo J 16: 545-554.
16. Lundgren K, Walworth N, Booher R, Dembski M, Kirschner M, et al. (1991) mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell 64: 1111-1122.
17. Parker LL, Atherton-Fessler S, Piwnica-Worms H, (1992) p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15. Proc Natl Acad Sci U S A 89: 2917-2921.
18. Bulavin DV, Higashimoto Y, Demidenko ZN, Meek S, Graves P, et al. (2003) Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nat Cell Biol 5: 545-551.
19. Chen MS, Ryan CE, Piwnica-Worms H, (2003) Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding. Mol Cell Biol 23: 7488-7497.
20. Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS, et al. (1997) Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 277: 1501-1505.
21. Graves PR, Lovly CM, Uy GL, Piwnica-Worms H, (2001) Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding. Oncogene 20: 1839-1851.
22. Prigent C, Dimitrov S, (2003) Phosphorylation of serine 10 in histone H3, what for? J Cell Sci 116: 3677-3685.
23. Goto H, Tomono Y, Ajiro K, Kosako H, Fujita M, et al. (1999) Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation. The Journal of biological chemistry 274: 25543-25549.
24. Xu B, Kastan MB, (2004) Analyzing cell cycle checkpoints after ionizing radiation. Methods Mol Biol 281: 283-292.
25. Hendzel MJ, Wei Y, Mancini MA, Van Hooser A, Ranalli T, et al. (1997) Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma 106: 348-360.
26. Sauve DM, Anderson HJ, Ray JM, James WM, Roberge M, (1999) Phosphorylation-induced rearrangement of the histone H3 NH2-terminal domain during mitotic chromosome condensation. J Cell Biol 145: 225-235.
27. Xu B, Kim ST, Lim DS, Kastan MB, (2002) Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation. Mol Cell Biol 22: 1049-1059.
28. Yan Y, Black CP, Cowan KH, (2007) Irradiation-induced G2/M checkpoint response requires ERK1/2 activation. Oncogene 26: 4689-4698.
29. O'Connell MJ, Cimprich KA, (2005) G2 damage checkpoints: what is the turn-on? J Cell Sci 118: 1-6.
30. Liu Q, Guntuku S, Cui XS, Matsuoka S, Cortez D, et al. (2000) Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes Dev 14: 1448-1459.
31. Zhao H, Piwnica-Worms H, (2001) ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol 21: 4129-4139.
32. Ward IM, Wu X, Chen J, (2001) Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks. J Biol Chem 276: 47755-47758.
33. Ahn JY, Schwarz JK, Piwnica-Worms H, Canman CE, (2000) Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation. Cancer Res 60: 5934-5936.
34. Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, et al. (1997) 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Mol Cell 1: 3-11.
35. Mitchell C, Hamed HA, Cruickshanks N, Tang Y, Bareford MD, et al. (2011) Simultaneous exposure of transformed cells to SRC family inhibitors and CHK1 inhibitors causes cell death. Cancer Biol Ther 12: 215-228.
36. Harper JW, Elledge SJ, Keyomarsi K, Dynlacht B, Tsai LH, et al. (1995) Inhibition of cyclin-dependent kinases by p21. Mol Biol Cell 6: 387-400.
37. Charrier-Savournin FB, Chateau MT, Gire V, Sedivy J, Piette J, et al. (2004) p21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress. Mol Biol Cell 15: 3965-3976.
38. Smits VA, Klompmaker R, Vallenius T, Rijksen G, Makela TP, et al. (2000) p21 inhibits Thr161 phosphorylation of Cdc2 to enforce the G2 DNA damage checkpoint. J Biol Chem 275: 30638-30643.
39. Cui W, Yazlovitskaya EM, Mayo MS, Pelling JC, Persons DL, (2000) Cisplatin-induced response of c-jun N-terminal kinase 1 and extracellular signal-regulated protein kinases 1 and 2 in a series of cisplatin-resistant ovarian carcinoma cell lines. Mol Carcinog 29: 219-228.
40. Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S, (2003) MAPK pathways in radiation responses. Oncogene 22: 5885-5896.
41. Wang X, Martindale JL, Holbrook NJ, (2000) Requirement for ERK activation in cisplatin-induced apoptosis. J Biol Chem 275: 39435-39443.
42. Pumiglia KM, Decker SJ, (1997) Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway. Proc Natl Acad Sci U S A 94: 448-452.
43. Reinhardt HC, Aslanian AS, Lees JA, Yaffe MB, (2007) p53-Deficient Cells Rely on ATM- and ATR-Mediated Checkpoint Signaling through the p38MAPK/MK2 Pathway for Survival after DNA Damage. Cancer Cell 11: 175-189.
44. Tang D, Wu D, Hirao A, Lahti JM, Liu L, et al. (2002) ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. J Biol Chem 277: 12710-12717.
45. Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, et al. (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273: 18623-18632.
46. Foster SA, Demers GW, Etscheid BG, Galloway DA, (1994) The ability of human papillomavirus E6 proteins to target p53 for degradation in vivo correlates with their ability to abrogate actinomycin D-induced growth arrest. J Virol 68: 5698-5705.
47. Yan Y, Black CP, Cao PT, Haferbier JL, Kolb RH, et al. (2008) Gamma-irradiation-induced DNA damage checkpoint activation involves feedback regulation between extracellular signal-regulated kinase 1/2 and BRCA1. Cancer Res 68: 5113-5121.
48. Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hosteller R, et al. (1989) Mutations in the p53 gene occur in diverse human tumour types. Nature 342: 705-708.
49. Willis A, Jung EJ, Wakefield T, Chen X, (2004) Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes. Oncogene 23: 2330-2338.
50. Yan Y, Shay JW, Wright WE, Mumby MC, (1997) Inhibition of protein phosphatase activity induces p53-dependent apoptosis in the absence of p53 transactivation. J Biol Chem 272: 15220-15226.
51. Yan Y, Spieker RS, Kim M, Stoeger SM, Cowan KH, (2005) BRCA1-mediated G2/M cell cycle arrest requires ERK1/2 kinase activation. Oncogene 24: 3285-3296.
52. Gatei M, Scott SP, Filippovitch I, Soronika N, Lavin MF, et al. (2000) Role for ATM in DNA damage-induced phosphorylation of BRCA1. Cancer Res 60: 3299-3304.
53. Canman CE, Lim DS, Cimprich KA, Taya Y, Tamai K, et al. (1998) Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281: 1677-1679.
54. Sarkaria JN, Busby EC, Tibbetts RS, Roos P, Taya Y, et al. (1999) Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res 59: 4375-4382.
55. Hall-Jackson CA, Cross DA, Morrice N, Smythe C, (1999) ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK. Oncogene 18: 6707-6713.
56. Yarden RI, Pardo-Reoyo S, Sgagias M, Cowan KH, Brody LC, (2002) BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage. Nat Genet 30: 285-289.
57. Yu Q, La Rose J, Zhang H, Takemura H, Kohn KW, et al. (2002) UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1. Cancer Res 62: 5743-5748.
58. McGowan CH, Russell P, (1993) Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15. Embo J 12: 75-85.
59. McGowan CH, Russell P, (1995) Cell cycle regulation of human WEE1. Embo J 14: 2166-2175.
60. Yan Y, Mumby MC, (1999) Distinct roles for PP1 and PP2A in phosphorylation of the retinoblastoma protein. PP2a regulates the activities of G(1) cyclin-dependent kinases. J Biol Chem 274: 31917-31924.
61. Wu W, Sato K, Koike A, Nishikawa H, Koizumi H, et al. (2010) HERC2 Is an E3 Ligase That Targets BRCA1 for Degradation. Cancer Research 70: 6384-6392.
62. Yan Y, Haas JP, Kim M, Sgagias MK, Cowan KH, (2002) BRCA1-induced apoptosis involves inactivation of ERK1/2 activities. J Biol Chem 277: 33422-33430.
63. Wang X, Gorospe M, Huang Y, Holbrook NJ, (1997) p27Kip1 overexpression causes apoptotic death of mammalian cells. Oncogene 15: 2991-2997.
64. Reinhardt HC, Yaffe MB, (2009) Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2. Current Opinion in Cell Biology 21: 245-255.
65. Xu B, Kim S, Kastan MB, (2001) Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation. Mol Cell Biol 21: 3445-3450.
66. Abraham RT, (2001) Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 15: 2177-2196.
67. Lacroix M, Toillon R-A, Leclercq G, (2006) p53 and breast cancer, an update. Endocrine-Related Cancer 13: 293-325.
68. Andres JL, Fan S, Turkel GJ, Wang JA, Twu NF, et al. (1998) Regulation of BRCA1 and BRCA2 expression in human breast cancer cells by DNA-damaging agents. Oncogene 16: 2229-2241.
69. Lazebnik YA, Kaufmann SH, Desnoyers S, Poirier GG, Earnshaw WC, (1994) Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371: 346-347.
70. Liu WH, Chang LS, (2011) Fas/FasL-dependent and-independent activation of caspase-8 in doxorubicin-treated human breast cancer MCF-7 cells: ADAM10 down-regulation activates Fas/FasL signaling pathway. Int J Biochem Cell Biol 43: 1708-1719.
71. Iliakis G, Wang Y, Guan J, Wang H, (2003) DNA damage checkpoint control in cells exposed to ionizing radiation. Oncogene 22: 5834-5847.
72. Wei F, Xie Y, Tao L, Tang D, (2010) Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation. Cell Signal 22: 1783-1789.
73. Ho CC, Siu WY, Chow JP, Lau A, Arooz T, et al. (2005) The relative contribution of CHK1 and CHK2 to Adriamycin-induced checkpoint. Exp Cell Res 304: 1-15.
74. O'Connor PM, Jackman J, Bae I, Myers TG, Fan S, et al. (1997) Characterization of the p53 Tumor Suppressor Pathway in Cell Lines of the National Cancer Institute Anticancer Drug Screen and Correlations with the Growth-Inhibitory Potency of 123 Anticancer Agents. Cancer Research 57: 4285-4300.
75. Brantley-Finley C, Lyle CS, Du L, Goodwin ME, Hall T, et al. (2003) The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide. Biochem Pharmacol 66: 459-469.
76. Liu SQ, Yu JP, Yu HG, Lv P, Chen HL, (2006) Activation of Akt and ERK signalling pathways induced by etoposide confer chemoresistance in gastric cancer cells. Dig Liver Dis 38: 310-318.
77. Lee ER, Kim JY, Kang YJ, Ahn JY, Kim JH, et al. (2006) Interplay between PI3K/Akt and MAPK signaling pathways in DNA-damaging drug-induced apoptosis. Biochim Biophys Acta 1763: 958-968.
78. Navarro R, Busnadiego I, Ruiz-Larrea MB, Ruiz-Sanz JI, (2006) Superoxide Anions Are Involved in Doxorubicin-Induced ERK Activation in Hepatocyte Cultures. Annals of the New York Academy of Sciences 1090: 419-428.
79. Gewirtz DA, (2000) Growth arrest and cell death in the breast tumor cell in response to ionizing radiation and chemotherapeutic agents which induce DNA damage. Breast Cancer Research and Treatment 62: 223-235.
80. Chang BD, Xuan Y, Broude EV, Zhu H, Schott B, et al. (1999) Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs. Oncogene 18: 4808-4818.