Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes

Oncogene

Volumn 23, Issue 13, 2004, Pages 2330-2338

  Willis, Amy ^a   Jung, Eun Joo ^a   Wakefield, Therese ^a   Chen, Xinbin ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b MCLM 660 ^*  (United States)

Author keywords

Cell cycle arrest; Mutant p53; p53; Transcription

Indexed keywords

MUTANT PROTEIN; PROTEIN; PROTEIN MDM2; PROTEIN P21; PROTEIN P53; PROTEIN P53 INDUCIBLE PROTEIN 3; UNCLASSIFIED DRUG; DNA;

ARTICLE; BINDING KINETICS; CARCINOGENESIS; CELL LINE; CHROMATIN; GENE TARGETING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MISSENSE MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INDUCTION; WILD TYPE; CELL CYCLE; DOMINANT GENE; GENETICS; MUTATION; PHYSIOLOGY; TRANSACTIVATION;

CELL CYCLE; DNA; GENES, DOMINANT; MUTATION; PROMOTER REGIONS (GENETICS); TRANS-ACTIVATION (GENETICS); TUMOR SUPPRESSOR PROTEIN P53;

EID: 1842536849     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207396     Document Type: Article

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