메뉴 건너뛰기




Volumn 1763, Issue 9, 2006, Pages 958-968

Interplay between PI3K/Akt and MAPK signaling pathways in DNA-damaging drug-induced apoptosis

Author keywords

Akt; Apoptosis; DNA damaging drug; Doxorubicin; ERK; Etoposide

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANTINEOPLASTIC AGENT; DNA; DOXORUBICIN; ETOPOSIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE;

EID: 33748464742     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2006.06.006     Document Type: Article
Times cited : (153)

References (54)
  • 1
    • 0036480586 scopus 로고    scopus 로고
    • Targeting apoptosis in cancer chemotherapy
    • Makin G. Targeting apoptosis in cancer chemotherapy. Expert Opin. Ther. Targets 6 (2002) 73-84
    • (2002) Expert Opin. Ther. Targets , vol.6 , pp. 73-84
    • Makin, G.1
  • 2
    • 0023028913 scopus 로고
    • Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical
    • Doroshow J.H., and Davies K.J. Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical. J. Biol. Chem. 261 (1986) 3068-3074
    • (1986) J. Biol. Chem. , vol.261 , pp. 3068-3074
    • Doroshow, J.H.1    Davies, K.J.2
  • 3
    • 0032949934 scopus 로고    scopus 로고
    • Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin
    • Persons D.L., Yazlovitskaya E.M., Cui W., and Pelling J.C. Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin. Clin. Cancer Res. 5 (1999) 1007-1014
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1007-1014
    • Persons, D.L.1    Yazlovitskaya, E.M.2    Cui, W.3    Pelling, J.C.4
  • 4
    • 0034671751 scopus 로고    scopus 로고
    • Requirement for ERK activation in cisplatin-induced apoptosis
    • Wang X., Martindale J.L., and Holbrook N.J. Requirement for ERK activation in cisplatin-induced apoptosis. J. Biol. Chem. 275 (2000) 39435-39443
    • (2000) J. Biol. Chem. , vol.275 , pp. 39435-39443
    • Wang, X.1    Martindale, J.L.2    Holbrook, N.J.3
  • 5
    • 0030272630 scopus 로고    scopus 로고
    • Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis
    • Yu R., Shtil A.A., Tan T.H., Roninson I.B., and Kong A.N. Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis. Cancer Lett. 107 (1996) 73-81
    • (1996) Cancer Lett. , vol.107 , pp. 73-81
    • Yu, R.1    Shtil, A.A.2    Tan, T.H.3    Roninson, I.B.4    Kong, A.N.5
  • 6
    • 0034608083 scopus 로고    scopus 로고
    • Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases
    • Kang Y.J., Zhou Z.X., Wang G.W., Buridi A., and Klein J.B. Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases. J. Biol. Chem. 275 (2000) 13690-13698
    • (2000) J. Biol. Chem. , vol.275 , pp. 13690-13698
    • Kang, Y.J.1    Zhou, Z.X.2    Wang, G.W.3    Buridi, A.4    Klein, J.B.5
  • 7
    • 0035253794 scopus 로고    scopus 로고
    • Hyperphosphorylation of tau is mediated by ERK activation during anticancer drug-induced apoptosis in neuroblastoma cells
    • Guise S., Braguer D., Carles G., Delacourte A., and Briand C. Hyperphosphorylation of tau is mediated by ERK activation during anticancer drug-induced apoptosis in neuroblastoma cells. J. Neurosci. Res. 63 (2001) 257-267
    • (2001) J. Neurosci. Res. , vol.63 , pp. 257-267
    • Guise, S.1    Braguer, D.2    Carles, G.3    Delacourte, A.4    Briand, C.5
  • 8
    • 0035970041 scopus 로고    scopus 로고
    • Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction
    • Negoro S., Oh H., Tone E., Kunisada K., Fujio Y., Walsh K., Kishimoto T., and Yamauchi-Takihara K. Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction. Circulation 103 (2001) 555-561
    • (2001) Circulation , vol.103 , pp. 555-561
    • Negoro, S.1    Oh, H.2    Tone, E.3    Kunisada, K.4    Fujio, Y.5    Walsh, K.6    Kishimoto, T.7    Yamauchi-Takihara, K.8
  • 12
    • 0031034574 scopus 로고    scopus 로고
    • Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
    • Kulik G., Klippel A., and Weber M.J. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol. Cell. Biol. 17 (1997) 1595-1606
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1595-1606
    • Kulik, G.1    Klippel, A.2    Weber, M.J.3
  • 13
    • 0032928614 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human
    • Widmann C., Gibson S., Jarpe M.B., and Johnson G.L. Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol. Rev. 79 (1999) 143-180
    • (1999) Physiol. Rev. , vol.79 , pp. 143-180
    • Widmann, C.1    Gibson, S.2    Jarpe, M.B.3    Johnson, G.L.4
  • 14
    • 0035735754 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy
    • Fan M., and Chambers T.C. Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy. Drug Resist. Updat. 4 (2001) 253-267
    • (2001) Drug Resist. Updat. , vol.4 , pp. 253-267
    • Fan, M.1    Chambers, T.C.2
  • 16
    • 6344289486 scopus 로고    scopus 로고
    • Negative regulation of MEKK1-induced signaling by glutathione S-transferase Mu
    • Ryoo K., Huh S.H., Lee Y.H., Yoon K.W., Cho S.G., and Choi E.J. Negative regulation of MEKK1-induced signaling by glutathione S-transferase Mu. J. Biol. Chem. 279 (2004) 43589-43594
    • (2004) J. Biol. Chem. , vol.279 , pp. 43589-43594
    • Ryoo, K.1    Huh, S.H.2    Lee, Y.H.3    Yoon, K.W.4    Cho, S.G.5    Choi, E.J.6
  • 17
    • 3843074548 scopus 로고    scopus 로고
    • Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells
    • Zhao Y., You H., Yang Y., Wei L., Zhang X., Yao L., Fan D., and Yu Q. Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells. J. Cell. Biochem. 91 (2004) 621-632
    • (2004) J. Cell. Biochem. , vol.91 , pp. 621-632
    • Zhao, Y.1    You, H.2    Yang, Y.3    Wei, L.4    Zhang, X.5    Yao, L.6    Fan, D.7    Yu, Q.8
  • 18
    • 24744448676 scopus 로고    scopus 로고
    • Modulation of apoptosis in HaCaT keratinocytes via differential regulation of ERK signaling pathway by flavonoids
    • Lee E.R., Kang Y.J., Kim J.H., Lee H.T., and Cho S.G. Modulation of apoptosis in HaCaT keratinocytes via differential regulation of ERK signaling pathway by flavonoids. J. Biol. Chem. 280 (2005) 31498-31507
    • (2005) J. Biol. Chem. , vol.280 , pp. 31498-31507
    • Lee, E.R.1    Kang, Y.J.2    Kim, J.H.3    Lee, H.T.4    Cho, S.G.5
  • 19
    • 0027278808 scopus 로고
    • Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells
    • Ling Y.H., Priebe W., and Perez-Soler R. Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells. Cancer Res. 53 (1993) 1845-1852
    • (1993) Cancer Res. , vol.53 , pp. 1845-1852
    • Ling, Y.H.1    Priebe, W.2    Perez-Soler, R.3
  • 20
    • 0027237540 scopus 로고
    • Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells
    • Skladanowski A., and Konopa J. Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells. Biochem. Pharmacol. 46 (1993) 375-382
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 375-382
    • Skladanowski, A.1    Konopa, J.2
  • 22
    • 0027423418 scopus 로고
    • Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
    • Hibi M., Lin A., Smeal T., Minden A., and Karin M. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev. 7 (1993) 2135-2148
    • (1993) Genes Dev. , vol.7 , pp. 2135-2148
    • Hibi, M.1    Lin, A.2    Smeal, T.3    Minden, A.4    Karin, M.5
  • 23
    • 0026635602 scopus 로고
    • Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun: regulation by the N-terminal delta domain
    • Adler V., Franklin C.C., and Kraft A.S. Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun: regulation by the N-terminal delta domain. Proc. Natl. Acad. Sci. U. S. A. 89 (1992) 5341-5345
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 5341-5345
    • Adler, V.1    Franklin, C.C.2    Kraft, A.S.3
  • 24
    • 0032570594 scopus 로고    scopus 로고
    • Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways
    • Wang T.H., Wang H.S., Ichijo H., Giannakakou P., Foster J.S., Fojo T., and Wimalasena J. Microtubule-interfering agents activate c-Jun N-terminal kinase/stress-activated protein kinase through both Ras and apoptosis signal-regulating kinase pathways. J. Biol. Chem. 273 (1998) 4928-4936
    • (1998) J. Biol. Chem. , vol.273 , pp. 4928-4936
    • Wang, T.H.1    Wang, H.S.2    Ichijo, H.3    Giannakakou, P.4    Foster, J.S.5    Fojo, T.6    Wimalasena, J.7
  • 25
    • 0033834860 scopus 로고    scopus 로고
    • [Arg(6), D-Trp(7,9), N(me)Phe(8)]-substance P (6-11) (antagonist G) induces AP-1 transcription and sensitizes cells to chemotherapy
    • MacKinnon A.C., Waters C., Rahman I., Harani N., Rintoul R., Haslett C., and Sethi T. [Arg(6), D-Trp(7,9), N(me)Phe(8)]-substance P (6-11) (antagonist G) induces AP-1 transcription and sensitizes cells to chemotherapy. Br. J. Cancer 83 (2000) 941-948
    • (2000) Br. J. Cancer , vol.83 , pp. 941-948
    • MacKinnon, A.C.1    Waters, C.2    Rahman, I.3    Harani, N.4    Rintoul, R.5    Haslett, C.6    Sethi, T.7
  • 26
    • 0034326818 scopus 로고    scopus 로고
    • Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells
    • Mandlekar S., Yu R., Tan T.H., and Kong A.N. Activation of caspase-3 and c-Jun NH2-terminal kinase-1 signaling pathways in tamoxifen-induced apoptosis of human breast cancer cells. Cancer Res. 60 (2000) 5995-6000
    • (2000) Cancer Res. , Issue.60 , pp. 5995-6000
    • Mandlekar, S.1    Yu, R.2    Tan, T.H.3    Kong, A.N.4
  • 27
    • 0036131785 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for mitoxantrone- and anisomycin-induced apoptosis in HL-60 cells
    • Stadheim T.A., and Kucera G.L. c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for mitoxantrone- and anisomycin-induced apoptosis in HL-60 cells. Leuk Res. 26 (2002) 55-65
    • (2002) Leuk Res. , vol.26 , pp. 55-65
    • Stadheim, T.A.1    Kucera, G.L.2
  • 28
    • 0029851730 scopus 로고    scopus 로고
    • Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs
    • Osborn M.T., and Chambers T.C. Role of the stress-activated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. J. Biol. Chem. 271 (1996) 30950-30955
    • (1996) J. Biol. Chem. , vol.271 , pp. 30950-30955
    • Osborn, M.T.1    Chambers, T.C.2
  • 29
    • 0032569019 scopus 로고    scopus 로고
    • Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase
    • Nemoto S., Xiang J., Huang S., and Lin A. Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase. J. Biol. Chem. 273 (1998) 16415-16420
    • (1998) J. Biol. Chem. , vol.273 , pp. 16415-16420
    • Nemoto, S.1    Xiang, J.2    Huang, S.3    Lin, A.4
  • 30
    • 0032478822 scopus 로고    scopus 로고
    • MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner
    • Zechner D., Craig R., Hanford D.S., McDonough P.M., Sabbadini R.A., and Glembotski C.C. MKK6 activates myocardial cell NF-kappaB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner. J. Biol. Chem. 273 (1998) 8232-8239
    • (1998) J. Biol. Chem. , vol.273 , pp. 8232-8239
    • Zechner, D.1    Craig, R.2    Hanford, D.S.3    McDonough, P.M.4    Sabbadini, R.A.5    Glembotski, C.C.6
  • 31
    • 0034705626 scopus 로고    scopus 로고
    • p38 mitogen-activated protein kinase pathway protects adult rat ventricular myocytes against beta-adrenergic receptor-stimulated apoptosis. Evidence for Gi-dependent activation
    • Communal C., Colucci W.S., and Singh K. p38 mitogen-activated protein kinase pathway protects adult rat ventricular myocytes against beta-adrenergic receptor-stimulated apoptosis. Evidence for Gi-dependent activation. J. Biol. Chem. 275 (2000) 19395-19400
    • (2000) J. Biol. Chem. , vol.275 , pp. 19395-19400
    • Communal, C.1    Colucci, W.S.2    Singh, K.3
  • 32
    • 0034193343 scopus 로고    scopus 로고
    • A role for the p38 mitogen-activated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents
    • Sanchez-Prieto R., Rojas J.M., Taya Y., and Gutkind J.S. A role for the p38 mitogen-activated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents. Cancer Res. 60 (2000) 2464-2472
    • (2000) Cancer Res. , vol.60 , pp. 2464-2472
    • Sanchez-Prieto, R.1    Rojas, J.M.2    Taya, Y.3    Gutkind, J.S.4
  • 33
    • 0035158131 scopus 로고    scopus 로고
    • Involvement of p38 in apoptosis-associated membrane blebbing and nuclear condensation
    • Deschesnes R.G., Huot J., Valerie K., and Landry J. Involvement of p38 in apoptosis-associated membrane blebbing and nuclear condensation. Mol. Biol. Cell 12 (2001) 1569-1582
    • (2001) Mol. Biol. Cell , vol.12 , pp. 1569-1582
    • Deschesnes, R.G.1    Huot, J.2    Valerie, K.3    Landry, J.4
  • 35
    • 0035920148 scopus 로고    scopus 로고
    • MEK6 regulates human involucrin gene expression via a p38alpha- and p38delta-dependent mechanism
    • Dashti S.R., Efimova T., and Eckert R.L. MEK6 regulates human involucrin gene expression via a p38alpha- and p38delta-dependent mechanism. J. Biol. Chem. 276 (2001) 27214-27220
    • (2001) J. Biol. Chem. , vol.276 , pp. 27214-27220
    • Dashti, S.R.1    Efimova, T.2    Eckert, R.L.3
  • 36
    • 0032477854 scopus 로고    scopus 로고
    • Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
    • Cheng M., Sexl V., Sherr C.J., and Roussel M.F. Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 1091-1096
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 1091-1096
    • Cheng, M.1    Sexl, V.2    Sherr, C.J.3    Roussel, M.F.4
  • 37
    • 0029786329 scopus 로고    scopus 로고
    • Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway
    • Lavoie J.N., L'Allemain G., Brunet A., Muller R., and Pouyssegur J. Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. J. Biol. Chem. 271 (1996) 20608-20616
    • (1996) J. Biol. Chem. , vol.271 , pp. 20608-20616
    • Lavoie, J.N.1    L'Allemain, G.2    Brunet, A.3    Muller, R.4    Pouyssegur, J.5
  • 38
    • 0030863161 scopus 로고    scopus 로고
    • Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway
    • Kawada M., Yamagoe S., Murakami Y., Suzuki K., Mizuno S., and Uehara Y. Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway. Oncogene 15 (1997) 629-637
    • (1997) Oncogene , vol.15 , pp. 629-637
    • Kawada, M.1    Yamagoe, S.2    Murakami, Y.3    Suzuki, K.4    Mizuno, S.5    Uehara, Y.6
  • 39
    • 0035419867 scopus 로고    scopus 로고
    • ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways
    • Lenferink A.E., Busse D., Flanagan W.M., Yakes F.M., and Arteaga C.L. ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways. Cancer Res. 61 (2001) 6583-6591
    • (2001) Cancer Res. , vol.61 , pp. 6583-6591
    • Lenferink, A.E.1    Busse, D.2    Flanagan, W.M.3    Yakes, F.M.4    Arteaga, C.L.5
  • 40
    • 0033574536 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase pathway is required for activation-induced cell death of T cells
    • van den Brink M.R., Kapeller R., Pratt J.C., Chang J.H., and Burakoff S.J. The extracellular signal-regulated kinase pathway is required for activation-induced cell death of T cells. J. Biol. Chem. 274 (1999) 11178-11185
    • (1999) J. Biol. Chem. , vol.274 , pp. 11178-11185
    • van den Brink, M.R.1    Kapeller, R.2    Pratt, J.C.3    Chang, J.H.4    Burakoff, S.J.5
  • 41
    • 0032514918 scopus 로고    scopus 로고
    • BAD enables ceramide to signal apoptosis via Ras and Raf-1
    • Basu S., Bayoumy S., Zhang Y., Lozano J., and Kolesnick R. BAD enables ceramide to signal apoptosis via Ras and Raf-1. J. Biol. Chem. 273 (1998) 30419-30426
    • (1998) J. Biol. Chem. , vol.273 , pp. 30419-30426
    • Basu, S.1    Bayoumy, S.2    Zhang, Y.3    Lozano, J.4    Kolesnick, R.5
  • 45
    • 0036619301 scopus 로고    scopus 로고
    • Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway
    • Cheng J.Q., Jiang X., Fraser M., Li M., Dan H.C., Sun M., and Tsang B.K. Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway. Drug Resist. Updat. 5 (2002) 131-146
    • (2002) Drug Resist. Updat. , vol.5 , pp. 131-146
    • Cheng, J.Q.1    Jiang, X.2    Fraser, M.3    Li, M.4    Dan, H.C.5    Sun, M.6    Tsang, B.K.7
  • 46
    • 0038621384 scopus 로고    scopus 로고
    • Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death
    • Arlt A., Gehrz A., Muerkoster S., Vorndamm J., Kruse M.L., Folsch U.R., and Schafer H. Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death. Oncogene 22 (2003) 3243-3251
    • (2003) Oncogene , vol.22 , pp. 3243-3251
    • Arlt, A.1    Gehrz, A.2    Muerkoster, S.3    Vorndamm, J.4    Kruse, M.L.5    Folsch, U.R.6    Schafer, H.7
  • 48
    • 0038342509 scopus 로고    scopus 로고
    • AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance
    • Yuan Z.Q., Feldman R.I., Sussman G.E., Coppola D., Nicosia S.V., and Cheng J.Q. AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. J. Biol. Chem. 278 (2003) 23432-23440
    • (2003) J. Biol. Chem. , vol.278 , pp. 23432-23440
    • Yuan, Z.Q.1    Feldman, R.I.2    Sussman, G.E.3    Coppola, D.4    Nicosia, S.V.5    Cheng, J.Q.6
  • 51
    • 0034665134 scopus 로고    scopus 로고
    • Prevention of phosphatidylinositol 3′-kinase-Akt survival signaling pathway during topotecan-induced apoptosis
    • Nakashio A., Fujita N., Rokudai S., Sato S., and Tsuruo T. Prevention of phosphatidylinositol 3′-kinase-Akt survival signaling pathway during topotecan-induced apoptosis. Cancer Res. 60 (2000) 5303-5309
    • (2000) Cancer Res. , vol.60 , pp. 5303-5309
    • Nakashio, A.1    Fujita, N.2    Rokudai, S.3    Sato, S.4    Tsuruo, T.5
  • 53
    • 0037200054 scopus 로고    scopus 로고
    • The specificity of extracellular signal-regulated kinase 2 dephosphorylation by protein phosphatases
    • Zhou B., Wang Z.X., Zhao Y., Brautigan D.L., and Zhang Z.Y. The specificity of extracellular signal-regulated kinase 2 dephosphorylation by protein phosphatases. J. Biol. Chem. 277 (2002) 31818-31825
    • (2002) J. Biol. Chem. , vol.277 , pp. 31818-31825
    • Zhou, B.1    Wang, Z.X.2    Zhao, Y.3    Brautigan, D.L.4    Zhang, Z.Y.5
  • 54
    • 0037108204 scopus 로고    scopus 로고
    • Inhibition of PTPs by H(2)O(2) regulates the activation of distinct MAPK pathways
    • Lee K., and Esselman W.J. Inhibition of PTPs by H(2)O(2) regulates the activation of distinct MAPK pathways. Free Radical Biol. Med. 33 (2002) 1121-1132
    • (2002) Free Radical Biol. Med. , vol.33 , pp. 1121-1132
    • Lee, K.1    Esselman, W.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.