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Volumn 84, Issue 5, 2009, Pages 300-309

Doxorubicin exerts cytotoxic effects through cell cycle arrest and fas-mediated cell death

Author keywords

Apoptosis; Cell cycle arrest; Doxorubicin; Fas signaling; Murine lymphocytes

Indexed keywords

COMPLEMENTARY DNA; DOXORUBICIN; FAS ANTIGEN; MESSENGER RNA;

EID: 70349890757     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000245937     Document Type: Article
Times cited : (106)

References (26)
  • 1
    • 33745312299 scopus 로고    scopus 로고
    • Doxorubicin induces apoptosis by activation of caspase-3 in cultured cardiomyocytes in vitro and rat cardiac ventricles in vivo
    • Ueno M, Kakinuma Y, Yuhki K, Murakoshi N, Iemitsu M, Miyauchi T, Yamaguchi I: Doxorubicin induces apoptosis by activation of caspase-3 in cultured cardiomyocytes in vitro and rat cardiac ventricles in vivo. J Pharmacol Sci 2006; 101: 151-158.
    • (2006) J Pharmacol Sci , vol.101 , pp. 151-158
    • Ueno, M.1    Kakinuma, Y.2    Yuhki, K.3    Murakoshi, N.4    Iemitsu, M.5    Miyauchi, T.6    Yamaguchi, I.7
  • 2
    • 33644862211 scopus 로고    scopus 로고
    • Gamma-irradiation and doxorubicin treatment of normal human cells cause cell cycle arrest via different pathways
    • Lee SM, Youn B, Kim CS, Kim CS, Kang C, Kim J: Gamma-irradiation and doxorubicin treatment of normal human cells cause cell cycle arrest via different pathways. Mol Cells 2005; 20: 331-338.
    • (2005) Mol Cells , vol.20 , pp. 331-338
    • Lee, S.M.1    Youn, B.2    Kim, C.S.3    Kim, C.S.4    Kang, C.5    Kim, J.6
  • 3
    • 3042739342 scopus 로고    scopus 로고
    • TRAIL and chemotherapeutic drugs in cancer therapy
    • Wu XX, Ogawa O, Kakehi Y: TRAIL and chemotherapeutic drugs in cancer therapy. Vitam Horm 2004; 67: 365-383.
    • (2004) Vitam Horm , vol.67 , pp. 365-383
    • Wu, X.X.1    Ogawa, O.2    Kakehi, Y.3
  • 4
    • 12344274560 scopus 로고    scopus 로고
    • Involvement of doxorubicin-induced Fas expression in the antitumor effect of doxorubicin on Lewis lung carcinoma in vivo
    • Yoshimoto Y, Kawada M, Ikeda D, Ishizuka M: Involvement of doxorubicin-induced Fas expression in the antitumor effect of doxorubicin on Lewis lung carcinoma in vivo. Int Immunopharmacol 2005; 5: 281-288.
    • (2005) Int Immunopharmacol , vol.5 , pp. 281-288
    • Yoshimoto, Y.1    Kawada, M.2    Ikeda, D.3    Ishizuka, M.4
  • 6
    • 0032404536 scopus 로고    scopus 로고
    • The central executioner of apoptosis: Caspases or mitochondria?
    • Green D, Kroemer G: The central executioner of apoptosis: caspases or mitochondria? Trends Cell Biol 1998; 8: 267-271.
    • (1998) Trends Cell Biol , vol.8 , pp. 267-271
    • Green, D.1    Kroemer, G.2
  • 7
    • 33646394582 scopus 로고    scopus 로고
    • Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death
    • Swift LP, Rephaeli A, Nudelman A, Phillips DR, Cutts SM: Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death. Cancer Res 2006; 66: 4863-4871.
    • (2006) Cancer Res , vol.66 , pp. 4863-4871
    • Swift, L.P.1    Rephaeli, A.2    Nudelman, A.3    Phillips, D.R.4    Cutts, S.M.5
  • 8
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanism of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
    • Gewirtz DA: A critical evaluation of the mechanism of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 1999; 57: 727-741.
    • (1999) Biochem Pharmacol , vol.57 , pp. 727-741
    • Gewirtz, D.A.1
  • 9
    • 0026560782 scopus 로고
    • Clinical importance of anthracyclines in the treatment of acute myeloid leukemia
    • Wiernik PH, Dutcher JP: Clinical importance of anthracyclines in the treatment of acute myeloid leukemia. Leukemia 1992; 6: 67-69.
    • (1992) Leukemia , vol.6 , pp. 67-69
    • Wiernik, P.H.1    Dutcher, J.P.2
  • 10
    • 26944463091 scopus 로고    scopus 로고
    • Effects of anthracycline derivatives on human leukemia K562 cell growth and differentiation
    • Czyz M, Szulawska A, Bednarek AK, Duchler M: Effects of anthracycline derivatives on human leukemia K562 cell growth and differentiation. Biochem Pharmacol 2005; 70: 1431-1442.
    • (2005) Biochem Pharmacol , vol.70 , pp. 1431-1442
    • Czyz, M.1    Szulawska, A.2    Bednarek, A.K.3    Duchler, M.4
  • 12
    • 0035736491 scopus 로고    scopus 로고
    • The role of Fas and FasL as mediators of anticancer chemotherapy
    • Poulaki V, Mitsiades CS, Mitsiades N: The role of Fas and FasL as mediators of anticancer chemotherapy. Drug Resist Updat 2001; 4: 233-242.
    • (2001) Drug Resist Updat , vol.4 , pp. 233-242
    • Poulaki, V.1    Mitsiades, C.S.2    Mitsiades, N.3
  • 13
    • 33749020871 scopus 로고    scopus 로고
    • P53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts
    • Jackson JG, Pereira-Smith OM: p53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts. Cancer Res 2006; 66: 8356-8360.
    • (2006) Cancer Res , vol.66 , pp. 8356-8360
    • Jackson, J.G.1    Pereira-Smith, O.M.2
  • 14
    • 33846497262 scopus 로고    scopus 로고
    • Different levels of p53 induced either apoptosis or cell cycle arrest in a doxycycline-regulated hepatocellular carcinoma cell line in vitro
    • Lai PB, Chi TY, Chen GG: Different levels of p53 induced either apoptosis or cell cycle arrest in a doxycycline-regulated hepatocellular carcinoma cell line in vitro. Apoptosis 2007; 12: 387-393.
    • (2007) Apoptosis , vol.12 , pp. 387-393
    • Lai, P.B.1    Chi, T.Y.2    Chen, G.G.3
  • 17
    • 34748859710 scopus 로고    scopus 로고
    • Gadd45 in the response of hematopoietic cells to genotoxic stress
    • DOI 10.1016/j.bcmd.2007.06.006, PII S1079979607001222
    • Liebermann DA, Hoffman B: Gadd45 in the response of hematopoietic cells to genotoxic stress. Blood Cells Mol Dis 2007; 39:329-335. (Pubitemid 47484472)
    • (2007) Blood Cells, Molecules, and Diseases , vol.39 , Issue.3 , pp. 329-335
    • Liebermann, D.A.1    Hoffman, B.2
  • 20
    • 0025288204 scopus 로고
    • Morphological alterations induced by doxorubicin in B16 melanoma cells
    • Mariani M, Supino R: Morphological alterations induced by doxorubicin in B16 melanoma cells. Cancer Lett 1990; 51: 209-212.
    • (1990) Cancer Lett , vol.51 , pp. 209-212
    • Mariani, M.1    Supino, R.2
  • 21
    • 0030781018 scopus 로고    scopus 로고
    • Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way
    • Garmen S, Anel A, Lasierra P, Alava MA, Martinez-Lorenzo MJ, Pineiro A, Naval J: Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way. FEBS Lett 1997; 417: 360-364.
    • (1997) FEBS Lett , vol.417 , pp. 360-364
    • Garmen, S.1    Anel, A.2    Lasierra, P.3    Alava, M.A.4    Martinez-Lorenzo, M.J.5    Pineiro, A.6    Naval, J.7
  • 22
    • 22444447038 scopus 로고    scopus 로고
    • HPMA copolymer-bound doxorubicin induces apoptosis in human ovarian carcinoma cells by a Fas-independent pathway
    • Malugin A, Kopeckova P, Kopecek J: HPMA copolymer-bound doxorubicin induces apoptosis in human ovarian carcinoma cells by a Fas-independent pathway. Mol Pharm 2004; 1: 174-182.
    • (2004) Mol Pharm , vol.1 , pp. 174-182
    • Malugin, A.1    Kopeckova, P.2    Kopecek, J.3
  • 23
    • 0026560782 scopus 로고
    • Clinical importance of anthracyclines in the treatment of acute myeloid leukemia
    • Wiernik PH, Dutcher JP: Clinical importance of anthracyclines in the treatment of acute myeloid leukemia. Leukemia 1992; 6: 67-69.
    • (1992) Leukemia , vol.6 , pp. 67-69
    • Wiernik, P.H.1    Dutcher, J.P.2
  • 24
    • 33646687085 scopus 로고    scopus 로고
    • Monitoring the gene expression profiles of doxorubicin-resistant acute myelocytic leukemia cells by DNA microarray analysis
    • Song JH, Choi CH, Yeom HJ, Hwang SY, Kim TS: Monitoring the gene expression profiles of doxorubicin-resistant acute myelocytic leukemia cells by DNA microarray analysis. Life Sci 2006; 79: 193-202.
    • (2006) Life Sci , vol.79 , pp. 193-202
    • Song, J.H.1    Choi, C.H.2    Yeom, H.J.3    Hwang, S.Y.4    Kim, T.S.5
  • 25
    • 0029935682 scopus 로고    scopus 로고
    • Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells
    • Friesen C, Herr I, Krammer PH, Debatin KM: Involvement of the CD95 (APO-1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med 1997; 2: 574-577.
    • (1997) Nat Med , vol.2 , pp. 574-577
    • Friesen, C.1    Herr, I.2    Krammer, P.H.3    Debatin, K.M.4
  • 26
    • 0030781018 scopus 로고    scopus 로고
    • Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way
    • Garmen S, Anel A, Lasierra P, Alava MA, Martinez-Lorenzo MJ, Pineiro A, Naval J: Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way. FEBS Lett 1997; 417: 360-364.
    • (1997) FEBS Lett , vol.417 , pp. 360-364
    • Garmen, S.1    Anel, A.2    Lasierra, P.3    Alava, M.A.4    Martinez-Lorenzo, M.J.5    Pineiro, A.6    Naval, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.