Dependence of substrate binding and catalysis on pH, ionic strength, and temperature for thymine DNA glycosylase: Insights into recognition and processing of G·T mispairs

DNA Repair

Volumn 10, Issue 5, 2011, Pages 545-553

  Maiti, Atanu ^a   Drohat, Alexander C ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

5 Methylcytosine deamination; Base excision repair; CpG sites; Fluorescence; G T mispair

Indexed keywords

5 METHYLCYTOSINE; NUCLEIC ACID BASE; NUCLEOTIDE; THYMINE; THYMINE DNA GLYCOSYLASE;

ARTICLE; BASE PAIRING; CHROMATIN; CPG ISLAND; DEAMINATION; EMBRYO DEVELOPMENT; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; IONIC STRENGTH; METHYLATION; MOLECULAR RECOGNITION; PH; PRIORITY JOURNAL; TEMPERATURE DEPENDENCE;

BASE PAIR MISMATCH; BASE SEQUENCE; CATALYSIS; DEOXYGUANOSINE; DNA; ENZYME ACTIVATION; ENZYME STABILITY; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; OSMOLAR CONCENTRATION; SUBSTRATE SPECIFICITY; TEMPERATURE; THYMIDINE; THYMINE DNA GLYCOSYLASE;

MAMMALIA;

EID: 79955119592     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2011.03.004     Document Type: Article

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