Mutagenicity of 5-formylcytosine, an oxidation product of 5-methylcytosine, in DNA in mammalian cells

Journal of Biochemistry

Volumn 132, Issue 4, 2002, Pages 551-555

  Kamiya, Hiroyuki ^a   Tsuchiya, Hiroyuki ^a   Karino, Naoko ^a   Ueno, Yoshihito ^a,b   Matsuda, Akira ^a   Harashima, Hideyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

5 formylcytosine; 5 methylcytosine; Mutation; Reactive oxygen species; Replication block

Indexed keywords

5 FORMYLCYTOSINE; 5 METHYLCYTOSINE; DNA; UNCLASSIFIED DRUG; CYTOSINE; DRUG DERIVATIVE; MUTAGENIC AGENT; OLIGODEOXYRIBONUCLEOTIDE;

ANIMAL CELL; ARTICLE; CELL STRAIN COS7; CONTROLLED STUDY; DNA REPLICATION; GENE MUTATION; MAMMAL; MOLECULAR RECOGNITION; MUTAGENICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; DNA DAMAGE; DNA TEMPLATE; DRUG EFFECT; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; METABOLISM; MUTATION; OXIDATION REDUCTION REACTION; PLASMID; SITE DIRECTED MUTAGENESIS;

ANIMALIA; ESCHERICHIA COLI; MAMMALIA; SIMIAE; VECTORS;

5-METHYLCYTOSINE; ANIMALS; BASE SEQUENCE; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOSINE; DNA DAMAGE; DNA REPLICATION; GENETIC VECTORS; MUTAGENESIS, SITE-DIRECTED; MUTAGENS; MUTATION; OLIGODEOXYRIBONUCLEOTIDES; OXIDATION-REDUCTION; PLASMIDS; TEMPLATES, GENETIC; TRANSFECTION;

EID: 0036773784     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a003256     Document Type: Article

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