Synthesis and properties of oligonucleotides containing 5-formyl-2′-deoxycytidine: In vitro DNA polymerase reactions on DNA templates containing 5-formyl-2′-deoxycytidine

Nucleic Acids Research

Volumn 29, Issue 12, 2001, Pages 2456-2463

  Karino, N ^a   Ueno, Y ^a   Matsuda, A ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ADENOSINE PHOSPHATE; CYTOSINE; DEOXYCYTIDINE; DNA; DNA POLYMERASE; FORMYLPEPTIDE; GUANINE; GUANOSINE PHOSPHATE; NUCLEOTIDE; OLIGODEOXYNUCLEOTIDE; OLIGONUCLEOTIDE; PERIODATE; PHOSPHORAMIDIC ACID; THYMINE;

ARTICLE; BASE PAIRING; CONTROLLED STUDY; DENATURATION; DNA SYNTHESIS; DNA TEMPLATE; ENZYME MECHANISM; ESCHERICHIA COLI; GENE INSERTION; GENE MUTATION; GENE SEQUENCE; IN VITRO STUDY; MOLECULAR STABILITY; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE METABOLISM; OXIDATION; PRIORITY JOURNAL; TECHNIQUE; TEMPERATURE;

ESCHERICHIA COLI;

EID: 0035875297     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.12.2456     Document Type: Article

References (33)

1. DNA methylation and gene function
2. The flip side of DNA methylation
3. DNA methylation and gene activity
4. Biological aspects of cytosine methylation in eukaryotic cells
5. DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
6. Methylation and imprinting: From host defense to gene regulation?
7. Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation
8. Patterns of DNA methylation-evolutionary vestiges of foreign DNA inactivation as a host defense mechanism. A proposal
9. 5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes
10. Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer
11. The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA
12. Heat- and alkali-induced deamination of 5-methylcytosine and cytosine residues in DNA
13. A cytosine methyltransferase converts 5-methylcytosine in DNA to thymine
14. Comparison of oxidation products from DNA components by γ-irradiation and Fenton-type reactions
15. Production of 5-formyluracil from thymine in an in vitro active oxygen-generating system
16. 5-Formyldeoxyuridine: A new type of DNA damage induced by ionizing radiation and its mutagenicity to salmonella strain TA102
17. Endogenous oxidative damage of deoxycytidine in DNA
18. Repair of products of oxidative DNA base damage in human cells
19. Substrate and mispairing properties of 5-formyl-2′-deoxyuridine 5′-triphosphate assessed by in vitro DNA polymerase reactions
20. The mutations induced by oxidatively damaged nucleotides, 5-formyl-dUTP and 5-hydroxy-dCTP, in Escherichia coli
21. 5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism
22. Photosensitized oxidation of 5-methyl-2′-deoxycytidine by 2-methyl-1,4-naphthoquinone: Characterization of 5-(hydroperoxymethyl)-2′-deoxycytidine and stable methyl group oxidation product
23. Photochemical deamination and demethylation of 5-methylcytosine
24. Formation of 5-formyl-2′-deoxycytidine from 5-methyl-2′-deoxycytidine in duplex DNA by fenton-type reactions and γ-irradiation
25. Met
26. Synthesis and characterization of isotopically enriched pyrimidine deoxynucleoside oxidation damage products
27. Synthesis and properties of oligonucleotides containing 5-formyl-2′-deoxyuridine
28. New synthetic method of 5-formyluracil-containing oligonucleotides and their melting behavior
29. Varied molecular interactions at the active sites of several DNA polymerases: Nonpolar nucleoside isosteres as probes
30. 2+-mobilizing second messenger cyclic ADP-ribose