2′-N-(pyren-1-yl)acetyl-2′-amino-α-L-LNA: Synthesis and detection of single nucleotide mismatches in DNA and RNA targets

ChemBioChem

Volumn 8, Issue 10, 2007, Pages 1122-1125

  Santhosh Kumar, T ^b   Wengel, Jesper ^b   Hrdlicka, Patrick J ^a  

^a UNIVERSITY OF IDAHO   (United States)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Intercalations; LNA; Nucleic acids; Pyrene; Single nucleotide polymorphism

Indexed keywords

2'(PYREN 1 YL) ACETYL 2' AMINO ALPHA LNA; NUCLEIC ACID; OLIGONUCLEOTIDE; PYRENE DERIVATIVE; UNCLASSIFIED DRUG; 2' N (PYREN 1 YL)ACETYL 2' AMINO ALPHA L LNA; 2'-N-(PYREN-1-YL)ACETYL-2'-AMINO-ALPHA-L-LNA; DNA; DRUG DERIVATIVE; NUCLEOTIDE; RNA; THYMIDINE PHOSPHATE;

ARTICLE; GENE MUTATION; GENE TARGETING; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SINGLE NUCLEOTIDE POLYMORPHISM; STEADY STATE; SYNTHESIS; BASE MISPAIRING; BIOLOGICAL MODEL; CHEMICAL MODEL; CHEMISTRY; CONFORMATION; GENETIC PROCEDURES; NUCLEIC ACID HYBRIDIZATION; SPECTROFLUOROMETRY; TEMPERATURE; THERMODYNAMICS;

BASE PAIR MISMATCH; DNA; GENETIC TECHNIQUES; MODELS, CHEMICAL; MODELS, GENETIC; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HYBRIDIZATION; NUCLEIC ACIDS; NUCLEOTIDES; RNA; SPECTROMETRY, FLUORESCENCE; TEMPERATURE; THERMODYNAMICS; THYMIDINE MONOPHOSPHATE;

EID: 34547600991     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200700144     Document Type: Article

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