-
1
-
-
34250632829
-
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125
-
Arimoto, K. I., Takahashi, H., Hishiki, T., Konishi, H., Fujita, T., and Shimotohno, K. (2007). Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125. Proc Natl Acad Sci U S A 104, 7500-7505.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 7500-7505
-
-
Arimoto, K.I.1
Takahashi, H.2
Hishiki, T.3
Konishi, H.4
Fujita, T.5
Shimotohno, K.6
-
2
-
-
79951679142
-
Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses
-
Barber, G. N. (2011). Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses. Curr Opin Immunol 23, 10-20.
-
(2011)
Curr Opin Immunol
, vol.23
, pp. 10-20
-
-
Barber, G.N.1
-
3
-
-
36549061966
-
Increased expression of eotaxin-3 distinguishes between eosinophilic esophagitis and gastroesophageal reflux disease
-
Bhattacharya, B., Carlsten, J., Sabo, E., Kethu, S., Meitner, P., Tavares, R., Jakate, S., Mangray, S., Aswad, B., and Resnick, M. B. (2007). Increased expression of eotaxin-3 distinguishes between eosinophilic esophagitis and gastroesophageal reflux disease. Hum Pathol 38, 1744-1753.
-
(2007)
Hum Pathol
, vol.38
, pp. 1744-1753
-
-
Bhattacharya, B.1
Carlsten, J.2
Sabo, E.3
Kethu, S.4
Meitner, P.5
Tavares, R.6
Jakate, S.7
Mangray, S.8
Aswad, B.9
Resnick, M.B.10
-
4
-
-
30444458235
-
Stats: multifaceted regulators of transcription
-
Brierley, M. M., and Fish, E. N. (2005). Stats: multifaceted regulators of transcription. J Interf Cytok Res 25, 733-744.
-
(2005)
J Interf Cytok Res
, vol.25
, pp. 733-744
-
-
Brierley, M.M.1
Fish, E.N.2
-
5
-
-
79954577277
-
TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk
-
Brown, J., Wang, H., Hajishengallis, G. N., and Martin, M. (2011). TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk. J Dent Res 90, 417-427.
-
(2011)
J Dent Res
, vol.90
, pp. 417-427
-
-
Brown, J.1
Wang, H.2
Hajishengallis, G.N.3
Martin, M.4
-
6
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Bürckstümmer, T., Baumann, C., Blüml, S., Dixit, E., Dürnberger, G., Jahn, H., Planyavsky, M., Bilban, M., Colinge, J., Bennett, K. L., et al. (2009). An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 10, 266-272.
-
(2009)
Nat Immunol
, vol.10
, pp. 266-272
-
-
Bürckstümmer, T.1
Baumann, C.2
Blüml, S.3
Dixit, E.4
Dürnberger, G.5
Jahn, H.6
Planyavsky, M.7
Bilban, M.8
Colinge, J.9
Bennett, K.L.10
-
7
-
-
0029865142
-
IRAK: a kinase associated with the interleukin-1 receptor
-
Cao, Z. D., Henzel, W. J., and Gao, X. (1996). IRAK: a kinase associated with the interleukin-1 receptor. Science 271, 1128-1131.
-
(1996)
Science
, vol.271
, pp. 1128-1131
-
-
Cao, Z.D.1
Henzel, W.J.2
Gao, X.3
-
8
-
-
77953991456
-
Regulation of the T helper cell type 2 (Th2)/T regulatory cell (Treg) balance by IL-4 and STAT6
-
Chapoval, S., Dasgupta, P., Dorsey, N. J., and Keegan, A. D. (2010). Regulation of the T helper cell type 2 (Th2)/T regulatory cell (Treg) balance by IL-4 and STAT6. J Leuk Biol 87, 1011-1018.
-
(2010)
J Leuk Biol
, vol.87
, pp. 1011-1018
-
-
Chapoval, S.1
Dasgupta, P.2
Dorsey, N.J.3
Keegan, A.D.4
-
9
-
-
80054694130
-
Activation of STAT6 by STING is critical for antiviral innate immunity
-
Chen, H. H., Sun, H., You, F. P., Sun, W. X., Zhou, X., Chen, L., Yang, J., Wang, Y. T., Tang, H., Guan, Y. K., et al. (2011). Activation of STAT6 by STING is critical for antiviral innate immunity. Cell 147, 436-446.
-
(2011)
Cell
, vol.147
, pp. 436-446
-
-
Chen, H.H.1
Sun, H.2
You, F.P.3
Sun, W.X.4
Zhou, X.5
Chen, L.6
Yang, J.7
Wang, Y.T.8
Tang, H.9
Guan, Y.K.10
-
10
-
-
23144449789
-
Ubiquitin signalling in the NF-κB pathway
-
Chen, Z. J. (2005). Ubiquitin signalling in the NF-κB pathway. Nat Cell Biol 7, 758-765.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 758-765
-
-
Chen, Z.J.1
-
11
-
-
81055129618
-
Systematic discovery of TLR signaling components delineates viral-sensing circuits
-
Chevrier, N., Mertins, P., Artyomov, M. N., Shalek, A. K., Iannacone, M., Ciaccio, M. F., Gat-Viks, I., Tonti, E., DeGrace, M. M., Clauser, K. R., et al. (2011). Systematic discovery of TLR signaling components delineates viral-sensing circuits. Cell 147, 853-867.
-
(2011)
Cell
, vol.147
, pp. 853-867
-
-
Chevrier, N.1
Mertins, P.2
Artyomov, M.N.3
Shalek, A.K.4
Iannacone, M.5
Ciaccio, M.F.6
Gat-Viks, I.7
Tonti, E.8
DeGrace, M.M.9
Clauser, K.R.10
-
12
-
-
77952503750
-
Peroxisomes are signaling platforms for antiviral innate immunity
-
Dixit, E., Boulant, S., Zhang, Y. J., Lee, A. S. Y., Odendall, C., Shum, B., Hacohen, N., Chen, Z. J., Whelan, S. P., Fransen, M., et al. (2010). Peroxisomes are signaling platforms for antiviral innate immunity. Cell 141, 668-681.
-
(2010)
Cell
, vol.141
, pp. 668-681
-
-
Dixit, E.1
Boulant, S.2
Zhang, Y.J.3
Lee, A.S.Y.4
Odendall, C.5
Shum, B.6
Hacohen, N.7
Chen, Z.J.8
Whelan, S.P.9
Fransen, M.10
-
13
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri, T., Yu, J.-W., Datta, P., Wu, J. H., and Alnemri, E. S. (2009). AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458, 509-513.
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.-W.2
Datta, P.3
Wu, J.H.4
Alnemri, E.S.5
-
14
-
-
30544451546
-
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
-
Häcker, H., Redecke, V., Blagoev, B., Kratchmarova, I., Hsu, L.-C., Wang, G. G., Kamps, M. P., Raz, E., Wagner, H., Häcker, G., et al. (2006). Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 439, 204-207.
-
(2006)
Nature
, vol.439
, pp. 204-207
-
-
Häcker, H.1
Redecke, V.2
Blagoev, B.3
Kratchmarova, I.4
Hsu, L.-C.5
Wang, G.G.6
Kamps, M.P.7
Raz, E.8
Wagner, H.9
Häcker, G.10
-
15
-
-
33744546660
-
Signaling mechanisms, interaction partners, and target genes of STAT6
-
Hebenstreit, D., Wirnsberger, G., Horejs-Hoeck, J., and Duschl, A. (2006). Signaling mechanisms, interaction partners, and target genes of STAT6. Cytokine Growth Factor Rev 17, 173-188.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 173-188
-
-
Hebenstreit, D.1
Wirnsberger, G.2
Horejs-Hoeck, J.3
Duschl, A.4
-
16
-
-
0035313367
-
STAT6 mediates eotaxin-1 expression in IL-4 or TNF-alpha-induced fibroblasts
-
Hoeck, J., and Woisetschläger, M. (2001). STAT6 mediates eotaxin-1 expression in IL-4 or TNF-alpha-induced fibroblasts. J Immunol 166, 4507-4515.
-
(2001)
J Immunol
, vol.166
, pp. 4507-4515
-
-
Hoeck, J.1
Woisetschläger, M.2
-
17
-
-
0035555301
-
TIRAP: an adaptor molecule in the Toll signaling pathway
-
Horng, T., Barton, G. M., and Medzhitov, R. (2001). TIRAP: an adaptor molecule in the Toll signaling pathway. Nat Immunol 2, 835-841.
-
(2001)
Nat Immunol
, vol.2
, pp. 835-841
-
-
Horng, T.1
Barton, G.M.2
Medzhitov, R.3
-
18
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung, V., Ablasser, A., Charrel-Dennis, M., Bauernfeind, F., Horvath, G., Caffrey, D. R., Latz, E., and Fitzgerald, K. A. (2009). AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458, 514-518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
Latz, E.7
Fitzgerald, K.A.8
-
19
-
-
33750976374
-
5′-Triphosphate RNA is the ligand for RIG-I
-
Hornung, V., Ellegast, J., Kim, S., Brzózka, K., Jung, A., Kato, H., Poeck, H., Akira, S., Conzelmann, K.-K., Schlee, M., et al. (2006). 5′-Triphosphate RNA is the ligand for RIG-I. Science 314, 994-997.
-
(2006)
Science
, vol.314
, pp. 994-997
-
-
Hornung, V.1
Ellegast, J.2
Kim, S.3
Brzózka, K.4
Jung, A.5
Kato, H.6
Poeck, H.7
Akira, S.8
Conzelmann, K.-K.9
Schlee, M.10
-
20
-
-
79961133270
-
MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response
-
Hou, F. J., Sun, L. J., Zheng, H., Skaug, B., Jiang, Q. X., and Chen, Z. J. (2011). MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response. Cell 146, 448-461.
-
(2011)
Cell
, vol.146
, pp. 448-461
-
-
Hou, F.J.1
Sun, L.J.2
Zheng, H.3
Skaug, B.4
Jiang, Q.X.5
Chen, Z.J.6
-
21
-
-
4944228934
-
Kit and FcepsilonRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells
-
Hundley, T. R., Gilfillan, A. M., Tkaczyk, C., Andrade, M. V., Metcalfe, D. D., Beaven, M. A. (2004). Kit and FcepsilonRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells. Blood 104, 2410-2417.
-
(2004)
Blood
, vol.104
, pp. 2410-2417
-
-
Hundley, T.R.1
Gilfillan, A.M.2
Tkaczyk, C.3
Andrade, M.V.4
Metcalfe, D.D.5
Beaven, M.A.6
-
22
-
-
70349943834
-
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
-
Ishikawa, H., Ma, Z., and Barber, G. N. (2009). STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 461, 788-792.
-
(2009)
Nature
, vol.461
, pp. 788-792
-
-
Ishikawa, H.1
Ma, Z.2
Barber, G.N.3
-
23
-
-
84862994793
-
Ubiquitin-induced oligomerization of the RNA sensors RIG-I and Mda5 activates antiviral innate immune response
-
Jiang, X. M., Kinch, L. N., Brautigam, C. A., Chen, X., Du, F. H., Grishin, N. V., and Chen, Z. J. (2012). Ubiquitin-induced oligomerization of the RNA sensors RIG-I and Mda5 activates antiviral innate immune response. Immunity 36, 959-973.
-
(2012)
Immunity
, vol.36
, pp. 959-973
-
-
Jiang, X.M.1
Kinch, L.N.2
Brautigam, C.A.3
Chen, X.4
Du, F.H.5
Grishin, N.V.6
Chen, Z.J.7
-
24
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato, H., Takeuchi, O., Sato, S., Yoneyama, M., Yamamoto, M., Matsui, K., Uematsu, S., Jung, A., Kawai, T., Ishii, K. J., et al. (2006). Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441, 101-105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
Matsui, K.6
Uematsu, S.7
Jung, A.8
Kawai, T.9
Ishii, K.J.10
-
25
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai, T., Adachi, O., Ogawa, T., Takeda, K., and Akira, S. (1999). Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11, 115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
26
-
-
27144440523
-
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
-
Kawai, T., Takahashi, K., Sato, S., Coban, C., Kumar, H., Kato, H., Ishii, K. J., Takeuchi, O., and Akira, S. (2005). IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction. Nat Immunol 6, 981-988.
-
(2005)
Nat Immunol
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
Coban, C.4
Kumar, H.5
Kato, H.6
Ishii, K.J.7
Takeuchi, O.8
Akira, S.9
-
27
-
-
80053379974
-
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
-
Kofoed, E. M., and Vance, R. E. (2011). Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477, 592-595.
-
(2011)
Nature
, vol.477
, pp. 592-595
-
-
Kofoed, E.M.1
Vance, R.E.2
-
28
-
-
78751560494
-
Pathogen recognition by the innate immune system
-
Kumar, H., Kawai, T., and Akira, S. (2011). Pathogen recognition by the innate immune system. Intl Rev Immunol 30, 16-34.
-
(2011)
Intl Rev Immunol
, vol.30
, pp. 16-34
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
29
-
-
34548656855
-
Signaling pathways downstream of pattern-recognition receptors and their cross talk
-
Lee, M. S., and Kim, Y. J. (2007). Signaling pathways downstream of pattern-recognition receptors and their cross talk. Annu Rev Biochem 76, 447-480.
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 447-480
-
-
Lee, M.S.1
Kim, Y.J.2
-
30
-
-
0037300319
-
The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE)
-
Mahad, D. J., and Ransohoff, R. M. (2003). The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Semin Immunol 15, 23-32.
-
(2003)
Semin Immunol
, vol.15
, pp. 23-32
-
-
Mahad, D.J.1
Ransohoff, R.M.2
-
31
-
-
0030694108
-
IRAK (Pelle) Family Member IRAK-2 AND MyD88 as Proximal Mediators of IL-1 Signaling
-
Marta, M., Jian, N., Ping, F., and Vishva, M. D. (1997). IRAK (Pelle) Family Member IRAK-2 AND MyD88 as Proximal Mediators of IL-1 Signaling. Science 278, 1612-1615.
-
(1997)
Science
, vol.278
, pp. 1612-1615
-
-
Marta, M.1
Jian, N.2
Ping, F.3
Vishva, M.D.4
-
32
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan, E., Curran, J., Hofmann, K., Moradpour, D., Binder, M., Bartenschlager, R., and Tschopp, J. (2005). Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437, 1167-1172.
-
(2005)
Nature
, vol.437
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
Moradpour, D.4
Binder, M.5
Bartenschlager, R.6
Tschopp, J.7
-
33
-
-
38749097018
-
NLRX1 is a regulator of mitochondrial antiviral immunity
-
Moore, C. B., Bergstralh, D. T., Duncan, J. A., Lei, Y., Morrison, T. E., Zimmermann, A. G., Accavitti-Loper, M. A., Madden, V. J., Sun, L. J., Ye, Z. M., et al. (2008). NLRX1 is a regulator of mitochondrial antiviral immunity. Nature 451, 573-577.
-
(2008)
Nature
, vol.451
, pp. 573-577
-
-
Moore, C.B.1
Bergstralh, D.T.2
Duncan, J.A.3
Lei, Y.4
Morrison, T.E.5
Zimmermann, A.G.6
Accavitti-Loper, M.A.7
Madden, V.J.8
Sun, L.J.9
Ye, Z.M.10
-
34
-
-
78650663605
-
Eotaxin-3/CC chemokine ligand 26 is a functional ligand for CX3CR1
-
Nakayama, T., Watanabe, Y., Oiso, N., Higuchi, T., Shigeta, A., Mizuguchi, N., Katou, F., Hashimoto, K., Kawada, A., and Yoshie, O. (2010). Eotaxin-3/CC chemokine ligand 26 is a functional ligand for CX3CR1. J Immunol 185, 6472-6479.
-
(2010)
J Immunol
, vol.185
, pp. 6472-6479
-
-
Nakayama, T.1
Watanabe, Y.2
Oiso, N.3
Higuchi, T.4
Shigeta, A.5
Mizuguchi, N.6
Katou, F.7
Hashimoto, K.8
Kawada, A.9
Yoshie, O.10
-
35
-
-
19644362276
-
Tissue-specific mRNA expression profiles of human toll-like receptors and related genes
-
Nishimura, M., and Naito, S. (2005). Tissue-specific mRNA expression profiles of human toll-like receptors and related genes. Biol Pharm Bull 28, 886-892.
-
(2005)
Biol Pharm Bull
, vol.28
, pp. 886-892
-
-
Nishimura, M.1
Naito, S.2
-
36
-
-
67749099300
-
Regulation of the innate immune response by threonine-phosphatase of Eyes absent
-
Okabe, Y., Sano, T., and Nagata, S. (2009). Regulation of the innate immune response by threonine-phosphatase of Eyes absent. Nature 460, 520-524.
-
(2009)
Nature
, vol.460
, pp. 520-524
-
-
Okabe, Y.1
Sano, T.2
Nagata, S.3
-
37
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Pétrilli, V., Papin, S., Dostert, C., Mayor, A., Martinon, F., and Tschopp, J. (2007). Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ 14, 1583-1589.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1583-1589
-
-
Pétrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
38
-
-
26844503987
-
The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I
-
Rothenfusser, S., Goutagny, N., Diperna, G., Monks, B. G., Schoenemeyer, A., Akira, S., Fitzgerald, K. A., Gong, M., and Yamamoto, M. (2005). The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I. J Immunol 175, 5260-5268.
-
(2005)
J Immunol
, vol.175
, pp. 5260-5268
-
-
Rothenfusser, S.1
Goutagny, N.2
Diperna, G.3
Monks, B.G.4
Schoenemeyer, A.5
Akira, S.6
Fitzgerald, K.A.7
Gong, M.8
Yamamoto, M.9
-
39
-
-
33846307026
-
Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2
-
Saito, T., Hirai, R., Loo, Y.-M., Owen, D., Johnson, C. L., Sinha, S. C., Akira, S., Fujita, T., and Gale, M., Jr. (2007). Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2. Proc Natl Acad Sci U S A 104, 582-587.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 582-587
-
-
Saito, T.1
Hirai, R.2
Loo, Y.-M.3
Owen, D.4
Johnson, C.L.5
Sinha, S.C.6
Akira, S.7
Fujita, T.8
Gale Jr., M.9
-
40
-
-
76549109497
-
LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses
-
Satoh, T., Kato, H., Kumagai, Y., Yoneyama, M., Sato, S., Matsushita, K., Tsujimura, T., Fujita, T., Akira, S., and Takeuchi, O. (2010). LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses. Proc Natl Acad Sci U S A 107, 1512-1517.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 1512-1517
-
-
Satoh, T.1
Kato, H.2
Kumagai, Y.3
Yoneyama, M.4
Sato, S.5
Matsushita, K.6
Tsujimura, T.7
Fujita, T.8
Akira, S.9
Takeuchi, O.10
-
41
-
-
77950362382
-
The inflammasomes
-
Schroder, K., and Tschopp, J. (2010). The inflammasomes. Cell 140, 821-832.
-
(2010)
Cell
, vol.140
, pp. 821-832
-
-
Schroder, K.1
Tschopp, J.2
-
42
-
-
49149126701
-
IL-4 is a critical determinant in the generation of allergic inflammation initiated by a constitutively active Stat6
-
Sehra, S., Bruns, H. A., Ahyi, A.-N. N., Nguyen, E. T., Schmidt, N. W., Michels, E. G., von Bülow, G.-U., and Kaplan, M. H. (2008). IL-4 is a critical determinant in the generation of allergic inflammation initiated by a constitutively active Stat6. J Immunol 180, 3551-3559.
-
(2008)
J Immunol
, vol.180
, pp. 3551-3559
-
-
Sehra, S.1
Bruns, H.A.2
Ahyi, A.-N.N.3
Nguyen, E.T.4
Schmidt, N.W.5
Michels, E.G.6
von Bülow, G.-U.7
Kaplan, M.H.8
-
43
-
-
77951890216
-
IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation
-
Sehra, S., Yao, Y. X., Howell, M. D., Nguyen, E. T., Kansas, G. S., Leung, D. Y. M., Travers, J. B., and Kaplan, M. H. (2010). IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation. J Immunol 184, 3186-3190.
-
(2010)
J Immunol
, vol.184
, pp. 3186-3190
-
-
Sehra, S.1
Yao, Y.X.2
Howell, M.D.3
Nguyen, E.T.4
Kansas, G.S.5
Leung, D.Y.M.6
Travers, J.B.7
Kaplan, M.H.8
-
44
-
-
24144461689
-
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF 3
-
Seth, R. B., Sun, L., Ea, C.-K., and Chen, Z. J. (2005). Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF 3. Cell 122, 669-682.
-
(2005)
Cell
, vol.122
, pp. 669-682
-
-
Seth, R.B.1
Sun, L.2
Ea, C.-K.3
Chen, Z.J.4
-
45
-
-
84856501373
-
Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling
-
Sun, L., Xing, Y. L., Chen, X. J., Zheng, Y., Yang, Y. D., Nichols, D. B., Clementz, M. A., Banach, B. S., Li, K., Baker, S. C., et al. (2012). Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling. PLoS ONE 7, e30802.
-
(2012)
PLoS ONE
, vol.7
-
-
Sun, L.1
Xing, Y.L.2
Chen, X.J.3
Zheng, Y.4
Yang, Y.D.5
Nichols, D.B.6
Clementz, M.A.7
Banach, B.S.8
Li, K.9
Baker, S.C.10
-
46
-
-
66649109939
-
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
-
Sun, W. X., Li, Y., Chen, L., Chen, H. H., You, F. P., Zhou, X., Zhou, Y., Zhai, Z. H., Chen, D. Y., and Jiang, Z. F. (2009). ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc Natl Acad Sci U S A 106, 8653-8658.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 8653-8658
-
-
Sun, W.X.1
Li, Y.2
Chen, L.3
Chen, H.H.4
You, F.P.5
Zhou, X.6
Zhou, Y.7
Zhai, Z.H.8
Chen, D.Y.9
Jiang, Z.F.10
-
47
-
-
84857937262
-
STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway
-
Tanaka, Y., and Chen. Z. J. (2012). STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway. Sci Signal 5, ra20.
-
(2012)
Sci Signal
, vol.5
-
-
Tanaka, Y.1
Chen, Z.J.2
-
48
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi, O., and Akira, S. (2010). Pattern recognition receptors and inflammation. Cell 140, 805-820.
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
49
-
-
34548418935
-
Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response
-
Thompson, A. J. V., and Locarnini, S. A. (2007). Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response. Immunol Cell Biol 85, 435-445.
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 435-445
-
-
Thompson, A.J.V.1
Locarnini, S.A.2
-
50
-
-
74049136127
-
Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines
-
Tseng, P.-H., Matsuzawa, A., Zhang, W. Z., Mino, T., Vignali, D. A. A., and Karin, M. (2010). Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines. Nat Immunol 11, 70-75.
-
(2010)
Nat Immunol
, vol.11
, pp. 70-75
-
-
Tseng, P.-H.1
Matsuzawa, A.2
Zhang, W.Z.3
Mino, T.4
Vignali, D.A.A.5
Karin, M.6
-
51
-
-
2142762520
-
TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression
-
Vogel, S. N., Fitzgerald, K. A., and Fenton, M. J. (2003). TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol Interv 3, 466-477.
-
(2003)
Mol Interv
, vol.3
, pp. 466-477
-
-
Vogel, S.N.1
Fitzgerald, K.A.2
Fenton, M.J.3
-
52
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang, C., Deng, L., Hong, M., Akkaraju, G. R., Inoue, J. I., and Chen, Z. J. (2001). TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412, 346-351.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.I.5
Chen, Z.J.6
-
53
-
-
34548459895
-
Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins
-
Watters, T. M., Kenny, E. F., and O'Neill, L. A. J. (2007). Structure, function and regulation of the Toll/IL-1 receptor adaptor proteins. Immunol Cell Biol 85, 411-419.
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 411-419
-
-
Watters, T.M.1
Kenny, E.F.2
O'Neill, L.A.J.3
-
54
-
-
35948941870
-
Critical link between TRAIL and CCL20 for the activation of TH2 cells and the expression of allergic airway disease
-
Weckmann, M., Collison, A., Simpson, J. L., Kopp, M. V., Wark, P. A. B., Smyth, M. J., Yagita, H., Matthaei, K. I., Hansbro, N., Whitehead, B., et al. (2007). Critical link between TRAIL and CCL20 for the activation of TH2 cells and the expression of allergic airway disease. Nat Med 13, 1308-1315.
-
(2007)
Nat Med
, vol.13
, pp. 1308-1315
-
-
Weckmann, M.1
Collison, A.2
Simpson, J.L.3
Kopp, M.V.4
Wark, P.A.B.5
Smyth, M.J.6
Yagita, H.7
Matthaei, K.I.8
Hansbro, N.9
Whitehead, B.10
-
55
-
-
33646941873
-
Organ-secific role of MyD88 for gene regulation during polymicrobial peritonitis
-
Weighardt, H., Mages, J., Jusek, G., Kaiser-Moore, S., Lang, R., and Holzmann, B. (2006). Organ-secific role of MyD88 for gene regulation during polymicrobial peritonitis. Infect Immun 74, 3618-3632.
-
(2006)
Infect Immun
, vol.74
, pp. 3618-3632
-
-
Weighardt, H.1
Mages, J.2
Jusek, G.3
Kaiser-Moore, S.4
Lang, R.5
Holzmann, B.6
-
56
-
-
34247588139
-
Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis
-
Winter, C., Taut, K., Srivastava, M., Länger, F., Mack, M., Briles, D. E., Paton, J. C., Maus, R., Welte, T., Gunn, M. D., et al. (2007). Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis. J Immunol 178, 5828-5838.
-
(2007)
J Immunol
, vol.178
, pp. 5828-5838
-
-
Winter, C.1
Taut, K.2
Srivastava, M.3
Länger, F.4
Mack, M.5
Briles, D.E.6
Paton, J.C.7
Maus, R.8
Welte, T.9
Gunn, M.D.10
-
57
-
-
24944538819
-
VISA is an adapter protein required for virus-triggered IFN-β signaling
-
Xu, L.-G., Wang, Y.-Y., Han, K.-J., Li, L.-Y., Zhai, Z. H., and Shu, H.-B. (2005). VISA is an adapter protein required for virus-triggered IFN-β signaling. Mol Cell 19, 727-740.
-
(2005)
Mol Cell
, vol.19
, pp. 727-740
-
-
Xu, L.-G.1
Wang, Y.-Y.2
Han, K.-J.3
Li, L.-Y.4
Zhai, Z.H.5
Shu, H.-B.6
-
58
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto, M., Sato, S., Hemmi, H., Hoshino, K., Kaisho, T., Sanjo, H., Takeuchi, O., Sugiyama, M., Okabe, M., Takeda, K., et al. (2003). Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301, 640-643.
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
-
59
-
-
77958114725
-
The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1
-
Yan, N., Regalado-Magdos, A. D., Stiggelbout, B., Lee-kirsch, M. A., and Lieberman, J. (2011). The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1. Nat Immunol 11, 1005-1013.
-
(2011)
Nat Immunol
, vol.11
, pp. 1005-1013
-
-
Yan, N.1
Regalado-Magdos, A.D.2
Stiggelbout, B.3
Lee-Kirsch, M.A.4
Lieberman, J.5
-
60
-
-
48949094095
-
Structural mechanism of RNA recognition by the RIG-I-like receptors
-
Yoneyama, M., and Fujita, T. (2008). Structural mechanism of RNA recognition by the RIG-I-like receptors. Immunity 29, 178-181.
-
(2008)
Immunity
, vol.29
, pp. 178-181
-
-
Yoneyama, M.1
Fujita, T.2
-
61
-
-
77951708374
-
Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity
-
Zeng, W. W., Sun, L. J., Jiang, X. M., Chen, X., Hou, F. J., Adhikari, A., Xu, M., and Chen, Z. J. (2010). Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell 141, 315-330.
-
(2010)
Cell
, vol.141
, pp. 315-330
-
-
Zeng, W.W.1
Sun, L.J.2
Jiang, X.M.3
Chen, X.4
Hou, F.J.5
Adhikari, A.6
Xu, M.7
Chen, Z.J.8
-
62
-
-
80053349020
-
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
-
Zhao, Y., Yang, J. L., Shi, J. J., Gong, Y.-N., Lu, Q. H., Xu, H., Liu, L. P., and Shao, F. (2011). The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477, 596-600.
-
(2011)
Nature
, vol.477
, pp. 596-600
-
-
Zhao, Y.1
Yang, J.L.2
Shi, J.J.3
Gong, Y.-N.4
Lu, Q.H.5
Xu, H.6
Liu, L.P.7
Shao, F.8
-
63
-
-
53349168904
-
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation
-
Zhong, B., Yang, Y., Li, S., Wang, Y.-Y., Li, Y., Diao, F. C., Lei, C. Q., He, X., Zhang, L., Tien, P., et al. (2008). The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity 29, 538-550.
-
(2008)
Immunity
, vol.29
, pp. 538-550
-
-
Zhong, B.1
Yang, Y.2
Li, S.3
Wang, Y.-Y.4
Li, Y.5
Diao, F.C.6
Lei, C.Q.7
He, X.8
Zhang, L.9
Tien, P.10
|