Eotaxin-3/CC chemokine ligand 26 is a functional ligand for CX3CR1

Journal of Immunology

Volumn 185, Issue 11, 2010, Pages 6472-6479

  Nakayama, Takashi ^a   Watanabe, Yoshiko ^d   Oiso, Naoki ^b   Higuchi, Tomonori ^a   Shigeta, Akiko ^a   Mizuguchi, Nobuyuki ^c   Katou, Fuminori ^d   Hashimoto, Kenji ^d   Kawada, Akira ^b   Yoshie, Osamu ^a  

^a Department of Microbiology ^*  (Japan)

^b Division of Gastroenterology and Hepatology   (Japan)

^c KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD16 ANTIGEN; CD27 ANTIGEN; CD45RA ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; EOTAXIN 3; FRACTALKINE; INTERLEUKIN 4; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ATOPIC DERMATITIS; CALCIUM TRANSPORT; CD8+ T LYMPHOCYTE; CELL ADHESION; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; MONOCYTE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PERITONEAL CAVITY; PRIORITY JOURNAL; PSORIASIS; REAL TIME POLYMERASE CHAIN REACTION;

ADULT; ANIMALS; CALCIUM SIGNALING; CELL LINE; CELLS, CULTURED; CHEMOKINES, CC; CHEMOTAXIS, LEUKOCYTE; HOMEOSTASIS; HUMANS; KILLER CELLS, NATURAL; LIGANDS; MALE; MICE; MICE, INBRED BALB C; MONOCYTES; RECEPTORS, CCR3; RECEPTORS, CHEMOKINE; T-LYMPHOCYTES, CYTOTOXIC;

EID: 78650663605     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0904126     Document Type: Article

References (48)

1. Yoshie, O., T. Imai, and H. Nomiyama. 2001. Chemokines in immunity. Adv. Immunol. 78:57-110.
2. Zlotnik, A., O. Yoshie, and H. Nomiyama. 2006. The chemokine and chemokine receptor superfamilies and their molecular evolution. Genome Biol. 7:243.
3. Daugherty, B. L., S. J. Siciliano, J. A. DeMartino, L. Malkowitz, A. Sirotina, and M. S. Springer. 1996. Cloning, expression, and characterization of the human eosinophil eotaxin receptor. J. Exp. Med. 183:2349-2354.
4. Ponath, P. D., S. Qin, T. W. Post, J. Wang, L. Wu, N. P. Gerard, W. Newman, C. Gerard, and C. R. Mackay. 1996. Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J. Exp. Med. 183:2437-2448.
5. Uguccioni, M., C. R. Mackay, B. Ochensberger, P. Loetscher, S. Rhis, G. J. LaRosa, P. Rao, P. D. Ponath, M. Baggiolini, and C. A. Dahinden. 1997. High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines. J. Clin. Invest. 100:1137-1143.
6. Gerber, B. O., M. P. Zanni, M. Uguccioni, M. Loetscher, C. R. Mackay, W. J. Pichler, N. Yawalkar, M. Baggiolini, and B. Moser. 1997. Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils. Curr. Biol. 7:836-843.
7. Sallusto, F., C. R. Mackay, and A. Lanzavecchia. 1997. Selective expression of the eotaxin receptor CCR3 by human T helper 2 cells. Science 277:2005-2007.
8. Kitaura, M., T. Nakajima, T. Imai, S. Harada, C. Combadiere, H. L. Tiffany, P. M. Murphy, and O. Yoshie. 1996. Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3. J. Biol. Chem. 271:7725-7730.
9. Kitaura, M., N. Suzuki, T. Imai, S. Takagi, R. Suzuki, T. Nakajima, K. Hirai, H. Nomiyama, and O. Yoshie. 1999. Molecular cloning of a novel human CC chemokine (eotaxin-3) that is a functional ligand of CC chemokine receptor 3. J. Biol. Chem. 274:27975-27980.
10. Heath, H., S. Qin, P. Rao, L. Wu, G. LaRosa, N. Kassam, P. D. Ponath, and C. R. Mackay. 1997. Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody. J. Clin. Invest. 99:178-184.
11. Forssmann, U., M. Uguccioni, P. Loetscher, C. A. Dahinden, H. Langen, M. Thelen, and M. Baggiolini. 1997. Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes. J. Exp. Med. 185:2171-2176.
12. Shinkai, A., H. Yoshisue, M. Koike, E. Shoji, S. Nakagawa, A. Saito, T. Takeda, S. Imabeppu, Y. Kato, N. Hanai, et al. 1999. A novel human CC chemokine, eotaxin-3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinophils. J. Immunol. 163:1602-1610.
13. Cuvelier, S. L., and K. D. Patel. 2001. Shear-dependent eosinophil transmigration on interleukin 4-stimulated endothelial cells: a role for endotheliumassociated eotaxin-3. J. Exp. Med. 194:1699-1709.
14. Øynebråten, I., O. Bakke, P. Brandtzaeg, F. E. Johansen, and G. Haraldsen. 2004. Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments. Blood 104:314-320.
15. Dulkys, Y., G. Schramm, D. Kimmig, S. Knöss, A. Weyergraf, A. Kapp, and J. Elsner. 2001. Detection of mRNA for eotaxin-2 and eotaxin-3 in human dermal fibroblasts and their distinct activation profile on human eosinophils. J. Invest. Dermatol. 116:498-505.
16. Komiya, A., H. Nagase, H. Yamada, T. Sekiya, M. Yamaguchi, Y. Sano, N. Hanai, A. Furuya, K. Ohta, K. Matsushima, et al. 2003. Concerted expression of eotaxin-1, eotaxin-2, and eotaxin-3 in human bronchial epithelial cells. Cell. Immunol. 225:91-100.
17. Zuyderduyn, S., P. S. Hiemstra, and K. F. Rabe. 2004. TGF-beta differentially regulates TH2 cytokine-induced eotaxin and eotaxin-3 release by human airway smooth muscle cells. J. Allergy Clin. Immunol. 114:791-798.
18. Blanchard, C., S. Durual, M. Estienne, S. Emami, S. Vasseur, and J. C. Cuber. 2005. Eotaxin-3/CCL26 gene expression in intestinal epithelial cells is up-regulated by interleukin-4 and interleukin-13 via the signal transducer and activator of transcription 6. Int. J. Biochem. Cell Biol. 37:2559-2573.
19. Kagami, S., H. Saeki, M. Komine, T. Kakinuma, Y. Tsunemi, K. Nakamura, K. Sasaki, A. Asahina, and K. Tamaki. 2005. Interleukin-4 and interleukin-13 enhance CCL26 production in a human keratinocyte cell line, HaCaT cells. Clin. Exp. Immunol. 141:459-466.
20. Kagami, S., T. Kakinuma, H. Saeki, Y. Tsunemi, H. Fujita, K. Nakamura, T. Takekoshi, M. Kishimoto, H. Mitsui, H. Torii, et al. 2003. Significant elevation of serum levels of eotaxin-3/CCL26, but not of eotaxin-2/CCL24, in patients with atopic dermatitis: serum eotaxin-3/CCL26 levels reflect the disease activity of atopic dermatitis. Clin. Exp. Immunol. 134:309-313.
21. Berkman, N., S. Ohnona, F. K. Chung, and R. Breuer. 2001. Eotaxin-3 but not eotaxin gene expression is upregulated in asthmatics 24 hours after allergen challenge. Am. J. Respir. Cell Mol. Biol. 24:682-687.
22. Polzer, K., T. Karonitsch, T. Neumann, G. Eger, C. Haberler, A. Soleiman, B. Hellmich, E. Csernok, J. Distler, B. Manger, et al. 2008. Eotaxin-3 is involved in Churg-Strauss syndrome-a serum marker closely correlating with disease activity. Rheumatology (Oxford) 47:804-808.
23. Blanchard, C., N. Wang, K. F. Stringer, A. Mishra, P. C. Fulkerson, J. P. Abonia, S. C. Jameson, C. Kirby, M. R. Konikoff, M. H. Collins, et al. 2006. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J. Clin. Invest. 116:536-547.
24. Bhattacharya, B., J. Carlsten, E. Sabo, S. Kethu, P. Meitner, R. Tavares, S. Jakate, S. Mangray, B. Aswad, and M. B. Resnick. 2007. Increased expression of eotaxin-3 distinguishes between eosinophilic esophagitis and gastroesophageal reflux disease. Hum. Pathol. 38:1744-1753.
25. Ogilvie, P., S. Paoletti, I. Clark-Lewis, and M. Uguccioni. 2003. Eotaxin-3 is a natural antagonist for CCR2 and exerts a repulsive effect on human monocytes. Blood 102:789-794.
26. Petkovic, V., C. Moghini, S. Paoletti, M. Uguccioni, and B. Gerber. 2004. Eotaxin-3/CCL26 is a natural antagonist for CC chemokine receptors 1 and 5. A human chemokine with a regulatory role. J. Biol. Chem. 279:23357-23363.
27. Imai, T., K. Hieshima, C. Haskell, M. Baba, M. Nagira, M. Nishimura, M. Kakizaki, S. Takagi, H. Nomiyama, T. J. Schall, and O. Yoshie. 1997. Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell 91:521-530.
28. Nishimura, M., H. Umehara, T. Nakayama, O. Yoneda, K. Hieshima, M. Kakizaki, N. Dohmae, O. Yoshie, and T. Imai. 2002. Dual functions of fractalkine/CX3C ligand 1 in trafficking of perforin+/granzyme B+ cytotoxic effector lymphocytes that are defined by CX3CR1 expression. J. Immunol. 168:6173-6180.
29. Geissmann, F., S. Jung, and D. R. Littman. 2003. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 19:71-82.
30. Yoshida, T., D. Izawa, T. Nakayama, K. Nakahara, M. Kakizaki, T. Imai, R. Suzuki, M. Miyasaka, and O. Yoshie. 1999. Molecular cloning of mXCR1, the murine SCM-1/lymphotactin receptor. FEBS Lett. 458:37-40.
31. Nakayama, T., Y. Kato, K. Hieshima, D. Nagakubo, Y. Kunori, T. Fujisawa, and O. Yoshie. 2004. Liver-expressed chemokine/CC chemokine ligand 16 attracts eosinophils by interacting with histamine H4 receptor. J. Immunol. 173:2078-2083.
32. Imai, T., M. Baba, M. Nishimura, M. Kakizaki, S. Takagi, and O. Yoshie. 1997. The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J. Biol. Chem. 272:15036-15042.
33. Bazan, J. F., K. B. Bacon, G. Hardiman, W. Wang, K. Soo, D. Rossi, D. R. Greaves, A. Zlotnik, and T. J. Schall. 1997. A new class of membranebound chemokine with a CX3C motif. Nature 385:640-644.
34. Fraticelli, P., M. Sironi, G. Bianchi, D. D'Ambrosio, C. Albanesi, A. Stoppacciaro, M. Chieppa, P. Allavena, L. Ruco, G. Girolomoni, et al. 2001. Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses. J. Clin. Invest. 107:1173-1181.
35. Butcher, E. C. 1991. Leukocyte-endothelial cell recognition: three (or more) steps to specificity and diversity. Cell 67:1033-1036.
36. Pope, S. M., P. C. Fulkerson, C. Blanchard, H. S. Akei, N. M. Nikolaidis, N. Zimmermann, J. D. Molkentin, and M. E. Rothenberg. 2005. Identification of a cooperative mechanism involving interleukin-13 and eotaxin-2 in experimental allergic lung inflammation. J. Biol. Chem. 280:13952-13961.
37. Oyoshi, M. K., R. He, L. Kumar, J. Yoon, and R. S. Geha. 2009. Cellular and molecular mechanisms in atopic dermatitis. Adv. Immunol. 102:135-226.
38. Lew, W., A. M. Bowcock, and J. G. Krueger. 2004. Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression. Trends Immunol. 25:295-305.
39. Werfel, T. 2009. The role of leukocytes, keratinocytes, and allergen-specific IgE in the development of atopic dermatitis. J. Invest. Dermatol. 129:1878-1891.
40. Pellegrino, M., B. Minervini, P. Musto, R. Matera, A. Greco, and C. Checchia de Ambrosio. 1996. Tumor necrosis factor-α and interleukin-1 β. Two possible mediators of allergic inflammation. Minerva Pediatr. 48:309-312.
41. Baggiolini, M. 1996. Eotaxin: a VIC (very important chemokine) of allergic inflammation? J. Clin. Invest. 97:587.
42. Gutierrez-Ramos, J. C., C. Lloyd, and J. A. Gonzalo. 1999. Eotaxin: from an eosinophilic chemokine to a major regulator of allergic reactions. Immunol. Today 20:500-504.
43. Ruth, J. H., M. V. Volin, G. K. Haines, III, D. C. Woodruff, K. J. Katschke, Jr., J. M. Woods, C. C. Park, J. C. Morel, and A. E. Koch. 2001. Fractalkine, a novel chemokine in rheumatoid arthritis and in rat adjuvant-induced arthritis. Arthritis Rheum. 44:1568-1581.
44. Umehara, H., E. T. Bloom, T. Okazaki, Y. Nagano, O. Yoshie, and T. Imai. 2004. Fractalkine in vascular biology: from basic research to clinical disease. Arterioscler. Thromb. Vasc. Biol. 24:34-40.
45. Yawalkar, N., S. Schmid, L. R. Braathen, and W. J. Pichler. 2001. Perforin and granzyme B may contribute to skin inflammation in atopic dermatitis and psoriasis. Br. J. Dermatol. 144:1133-1139.
46. Bratke, K., B. Böttcher, K. Leeder, S. Schmidt, M. Küpper, J. C. Virchow, Jr., and W. Luttmann. 2004. Increase in granzyme B+ lymphocytes and soluble granzyme B in bronchoalveolar lavage of allergen challenged patients with atopic asthma. Clin. Exp. Immunol. 136:542-548.
47. Ogg, G. 2009. Role of T cells in the pathogenesis of atopic dermatitis. Clin. Exp. Allergy 39:310-316.
48. Echigo, T., M. Hasegawa, Y. Shimada, K. Takehara, and S. Sato. 2004. Expression of fractalkine and its receptor, CX3CR1, in atopic dermatitis: possible contribution to skin inflammation. J. Allergy Clin. Immunol. 113:940-948.