-
1
-
-
67749102142
-
Toll-like receptors in ischemia-reperfusion injury
-
Arumugam TV, Okun E, Tang SC, Thundyil J, Taylor SM, Woodruff TM. Toll-like receptors in ischemia-reperfusion injury. Shock. 2009;32:4-16.
-
(2009)
Shock
, vol.32
, pp. 4-16
-
-
Arumugam, T.V.1
Okun, E.2
Tang, S.C.3
Thundyil, J.4
Taylor, S.M.5
Woodruff, T.M.6
-
2
-
-
33646478589
-
Therapeutic targeting of pattern-recognition receptors
-
Rezaei N. Therapeutic targeting of pattern-recognition receptors. Int Immunopharmacol. 2006;6:863-869.
-
(2006)
Int Immunopharmacol
, vol.6
, pp. 863-869
-
-
Rezaei, N.1
-
3
-
-
36049033394
-
Signaling to NF-kappaB by Toll-like receptors
-
Kawai T, Akira S. Signaling to NF-kappaB by Toll-like receptors. TrendsMolMed. 2007;13:460-469.
-
(2007)
TrendsMolMed
, vol.13
, pp. 460-469
-
-
Kawai, T.1
Akira, S.2
-
6
-
-
35748964708
-
Toll-like receptors 7, 8, and 9 linking innate immunity to autoimmunity
-
Krieg AM, Vollmer J. Toll-like receptors 7, 8, and 9: Linking innate immunity to autoimmunity. Immunol Rev. 2007;220:251-269.
-
(2007)
Immunol Rev
, vol.220
, pp. 251-269
-
-
Krieg, A.M.1
Vollmer, J.2
-
7
-
-
84855184185
-
Prophylactic and therapeutic implications of toll-like receptor ligands
-
Hedayat M, Takeda K, Rezaei N. Prophylactic and therapeutic implications of toll-like receptor ligands. Med Res Rev. 2012;32:294-325.
-
(2012)
Med Res Rev
, vol.32
, pp. 294-325
-
-
Hedayat, M.1
Takeda, K.2
Rezaei, N.3
-
8
-
-
9644287997
-
Toll-like receptor ligands: Hygiene, atopy and therapeutic implications
-
Horner AA, Redecke V, Raz E. Toll-like receptor ligands: Hygiene, atopy and therapeutic implications. Curr Opin Allergy Clin Immunol. 2004;4:555-561.
-
(2004)
Curr Opin Allergy Clin Immunol
, vol.4
, pp. 555-561
-
-
Horner, A.A.1
Redecke, V.2
Raz, E.3
-
9
-
-
33746716221
-
Activation of common antiviral pathways can potentiate inflammatory responses to septic shock
-
Doughty LA, Carlton S, Galen B, Cooma-Ramberan I, Chung CS, Ayala A. Activation of common antiviral pathways can potentiate inflammatory responses to septic shock. Shock. 2006;26:187-194.
-
(2006)
Shock
, vol.26
, pp. 187-194
-
-
Doughty, L.A.1
Carlton, S.2
Galen, B.3
Cooma-Ramberan, I.4
Chung, C.S.5
Ayala, A.6
-
10
-
-
43049179999
-
LPS/TLR4 signal transduction pathway
-
Lu YC, Yeh WC, Ohashi PS. LPS/TLR4 signal transduction pathway. Cytokine. 2008;42:145-151.
-
(2008)
Cytokine
, vol.42
, pp. 145-151
-
-
Lu, Y.C.1
Yeh, W.C.2
Ohashi, P.S.3
-
11
-
-
56749183908
-
Phagocytosis and antigen presentation: A partnership initiated by Toll-like receptors
-
Blander JM. Phagocytosis and antigen presentation: A partnership initiated by Toll-like receptors. Ann Rheum Dis. 2008;67 (Suppl 3):iii44-iii49.
-
(2008)
Ann Rheum Dis
, vol.67
, Issue.SUPPL. 3
-
-
Blander, J.M.1
-
12
-
-
20444479817
-
Lipopolysaccharide improves cardiomyocyte survival and function after serumdeprivation
-
Chao W, Shen Y, Zhu X, et al. Lipopolysaccharide improves cardiomyocyte survival and function after serumdeprivation. J Biol Chem. 2005;280:21997-2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 21997-22005
-
-
Chao, W.1
Shen, Y.2
Zhu, X.3
-
13
-
-
79952373888
-
Toll-like receptors, their ligands, and atherosclerosis
-
Hodgkinson CP, Ye S. Toll-like receptors, their ligands, and atherosclerosis. ScientificWorldJournal. 2011;11:437-453.
-
(2011)
ScientificWorldJournal
, vol.11
, pp. 437-453
-
-
Hodgkinson, C.P.1
Ye, S.2
-
14
-
-
33846828518
-
Hyaluronan inhibits osteoclast differentiation via Toll-like receptor 4
-
Chang EJ, Kim HJ, Ha J, et al. Hyaluronan inhibits osteoclast differentiation via Toll-like receptor 4. J Cell Sci. 2007;120:166-176.
-
(2007)
J Cell Sci
, vol.120
, pp. 166-176
-
-
Chang, E.J.1
Kim, H.J.2
Ha, J.3
-
15
-
-
0035451118
-
Fibrinogen stimulatesmacrophage chemokine secretion through toll-like receptor 4
-
Smiley ST, King JA,HancockWW.Fibrinogen stimulatesmacrophage chemokine secretion through toll-like receptor 4. J Immunol. 2001;167:2887-2894.
-
(2001)
J Immunol
, vol.167
, pp. 2887-2894
-
-
Smiley, S.T.1
King, J.A.2
Hancock, W.W.3
-
16
-
-
0035971217
-
The extra domain A of fibronectin activates Toll-like receptor 4
-
Okamura Y,WatariM, Jerud ES, et al. The extra domain A of fibronectin activates Toll-like receptor 4. J Biol Chem. 2001;276:10229-10233.
-
(2001)
J Biol Chem
, vol.276
, pp. 10229-10233
-
-
Okamura, Y.1
Watari, M.2
Jerud, E.S.3
-
17
-
-
36749042671
-
Human β-defensin-3 activates professional antigenpresenting cells via Toll-like receptors 1 and 2
-
Funderburg N, Lederman MM, Feng Z, et al. Human β-defensin-3 activates professional antigenpresenting cells via Toll-like receptors 1 and 2. Proc Natl Acad Sci U S A. 2007;104:18631-18635.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 18631-18635
-
-
Funderburg, N.1
Lederman, M.M.2
Feng, Z.3
-
18
-
-
33746731651
-
HMGB1 signals through toll-like receptor (TLR) 4 and TLR2
-
Yu M, Wang H, Ding A, et al. HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock. 2006;26:174-179.
-
(2006)
Shock
, vol.26
, pp. 174-179
-
-
Yu, M.1
Wang, H.2
Ding, A.3
-
19
-
-
0037094084
-
Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4
-
Johnson GB, Brunn GJ, Kodaira Y, Platt JL. Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4. J Immunol. 2002;168:5233-5239.
-
(2002)
J Immunol
, vol.168
, pp. 5233-5239
-
-
Johnson, G.B.1
Brunn, G.J.2
Kodaira, Y.3
Platt, J.L.4
-
20
-
-
24744442576
-
Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway
-
Cohen-Sfady M, Nussbaum G, Pevsner-Fischer M, et al. Heat shock protein 60 activates B cells via the TLR4-MyD88 pathway. J Immunol. 2005;175:3594-3602.
-
(2005)
J Immunol
, vol.175
, pp. 3594-3602
-
-
Cohen-Sfady, M.1
Nussbaum, G.2
Pevsner-Fischer, M.3
-
21
-
-
4344627821
-
Endogenous ligands of Toll-like receptors
-
Tsan MF, Gao B. Endogenous ligands of Toll-like receptors. J Leukoc Biol. 2004;76:514-519.
-
(2004)
J Leukoc Biol
, vol.76
, pp. 514-519
-
-
Tsan, M.F.1
Gao, B.2
-
22
-
-
0037177825
-
Novel signal transduction pathway utilized by extracellularHSP70: Role of toll-like receptor (TLR) 2 and TLR4
-
Asea A, RehliM,Kabingu E, et al.Novel signal transduction pathway utilized by extracellularHSP70: Role of toll-like receptor (TLR) 2 and TLR4. J Biol Chem. 2002;277:15028-15034.
-
(2002)
J Biol Chem
, vol.277
, pp. 15028-15034
-
-
Asea, A.1
Rehli, M.2
Kabingu, E.3
-
23
-
-
34547231172
-
Toll-like receptors in inflammation, infection and cancer
-
Chen K, Huang J, GongW, Iribarren P, Dunlop NM,Wang JM. Toll-like receptors in inflammation, infection and cancer. Int Immunopharmacol. 2007;7:1271-1285.
-
(2007)
Int Immunopharmacol
, vol.7
, pp. 1271-1285
-
-
Chen, K.1
Huang, J.2
Gong, W.3
Iribarren, P.4
Dunlop, N.M.5
Wang, J.M.6
-
24
-
-
33745840859
-
Hyaluronan fragments act as an endogenous danger signal by engaging TLR2
-
Scheibner KA, Lutz MA, Boodoo S, Fenton MJ, Powell JD,Horton MR. Hyaluronan fragments act as an endogenous danger signal by engaging TLR2. J Immunol. 2006;177:1272-1281.
-
(2006)
J Immunol
, vol.177
, pp. 1272-1281
-
-
Scheibner, K.A.1
Lutz, M.A.2
Boodoo, S.3
Fenton, M.J.4
Powell, J.D.5
Horton, M.R.6
-
25
-
-
0037065909
-
Inflammatory response after open heart surgery: Release of heat-shock protein 70 and signaling through toll-like receptor-4
-
Dybdahl B, Wahba A, Lien E, et al. Inflammatory response after open heart surgery: Release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation. 2002;105: 685-690.
-
(2002)
Circulation
, vol.105
, pp. 685-690
-
-
Dybdahl, B.1
Wahba, A.2
Lien, E.3
-
26
-
-
24644495576
-
Implication of Toll-like receptor and tumor necrosis factor alpha signaling in septic shock
-
LinWJ, YehWC. Implication of Toll-like receptor and tumor necrosis factor alpha signaling in septic shock. Shock. 2005;24:206-209.
-
(2005)
Shock
, vol.24
, pp. 206-209
-
-
Lin, W.J.1
Yeh, W.C.2
-
27
-
-
77955412192
-
The expression and functions of toll-like receptors in atherosclerosis
-
2010
-
Cole JE, Georgiou E,Monaco C.The expression and functions of toll-like receptors in atherosclerosis. Mediators Inflamm. 2010;2010:3939-3946.
-
(2010)
Mediators Inflamm
, pp. 3939-3946
-
-
Cole, J.E.1
Georgiou, E.2
Monaco, C.3
-
28
-
-
80051814602
-
Targeting of Toll-like receptors: A decade of progress in combating infectious diseases
-
HedayatM,Netea MG, RezaeiN. Targeting of Toll-like receptors: A decade of progress in combating infectious diseases. Lancet Infect Dis. 2011;11:702-712.
-
(2011)
Lancet Infect Dis
, vol.11
, pp. 702-712
-
-
Hedayat, M.1
Netea, M.G.2
Rezaei, N.3
-
29
-
-
58149500135
-
Toll-like receptor signaling: A criticalmodulator of cell survival and ischemic injury in the heart
-
Chao W. Toll-like receptor signaling: A criticalmodulator of cell survival and ischemic injury in the heart. Am J Physiol Heart Circ Physiol. 2009;296:H1-H12.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
-
-
Chao, W.1
-
30
-
-
48249107883
-
Clinical investigations of Toll-like receptor agonists
-
Meyer T, Stockfleth E. Clinical investigations of Toll-like receptor agonists. Expert Opin Investig Drugs. 2008;17:1051-1065.
-
(2008)
Expert Opin Investig Drugs
, vol.17
, pp. 1051-1065
-
-
Meyer, T.1
Stockfleth, E.2
-
31
-
-
33646147362
-
Toll-like receptor function and signaling
-
quiz 88
-
Kaisho T, Akira S. Toll-like receptor function and signaling. J Allergy Clin Immunol. 2006;117:979-987; quiz 88.
-
(2006)
J Allergy Clin Immunol
, vol.117
, pp. 979-987
-
-
Kaisho, T.1
Akira, S.2
-
32
-
-
33747338922
-
Jak/STAT/SOCS signaling circuits and associated cytokine-mediated inflammation and hypertrophy in the heart
-
Terrell AM, Crisostomo PR, Wairiuko GM, Wang M, Morrell ED, Meldrum DR. Jak/STAT/SOCS signaling circuits and associated cytokine-mediated inflammation and hypertrophy in the heart. Shock. 2006;26:226-234.
-
(2006)
Shock
, vol.26
, pp. 226-234
-
-
Terrell, A.M.1
Crisostomo, P.R.2
Wairiuko, G.M.3
Wang, M.4
Morrell, E.D.5
Meldrum, D.R.6
-
33
-
-
13644270638
-
Toll-like receptor 4 coupled GI protein signaling pathways regulate extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NFkappaB activation
-
Fan H, Peck OM, Tempel GE, Halushka PV, Cook JA. Toll-like receptor 4 coupled GI protein signaling pathways regulate extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NFkappaB activation. Shock. 2004;22:57-62.
-
(2004)
Shock
, vol.22
, pp. 57-62
-
-
Fan, H.1
Peck, O.M.2
Tempel, G.E.3
Halushka, P.V.4
Cook, J.A.5
-
34
-
-
48749085127
-
Plasmacytoid dendritic cells: Sensing nucleic acids in viral infection and autoimmune diseases
-
Gilliet M, Cao W, Liu YJ. Plasmacytoid dendritic cells: Sensing nucleic acids in viral infection and autoimmune diseases. Nat Rev Immunol. 2008;8:594-606.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 594-606
-
-
Gilliet, M.1
Cao, W.2
Liu, Y.J.3
-
35
-
-
0037484345
-
Species-specific regulation of Toll-like receptor 3 genes in men and mice
-
Heinz S, Haehnel V, Karaghiosoff M, et al. Species-specific regulation of Toll-like receptor 3 genes in men and mice. J Biol Chem. 2003;278:21502-509.
-
(2003)
J Biol Chem
, vol.278
, pp. 21502-21509
-
-
Heinz, S.1
Haehnel, V.2
Karaghiosoff, M.3
-
36
-
-
65549092335
-
Innate immunity and toll-like receptor antagonists: A potential role in the treatment of cardiovascular diseases
-
Lin E, Freedman JE, Beaulieu LM. Innate immunity and toll-like receptor antagonists: A potential role in the treatment of cardiovascular diseases. CardiovascTher. 2009;27:117-123.
-
(2009)
CardiovascTher
, vol.27
, pp. 117-123
-
-
Lin, E.1
Freedman, J.E.2
Beaulieu, L.M.3
-
37
-
-
3042702881
-
Inflammatory cytokines and postmyocardial infarction remodeling
-
Nian M, Lee P,KhaperN, Liu P. Inflammatory cytokines and postmyocardial infarction remodeling. Circ Res. 2004;94:1543-1553.
-
(2004)
Circ Res
, vol.94
, pp. 1543-1553
-
-
Nian, M.1
Lee, P.2
Khaper, N.3
Liu, P.4
-
38
-
-
33947108375
-
Triggers of inflammation after renal ischemia/reperfusion
-
Thurman JM. Triggers of inflammation after renal ischemia/reperfusion. Clin Immunol. 2007;123:7-13.
-
(2007)
Clin Immunol
, vol.123
, pp. 7-13
-
-
Thurman, J.M.1
-
39
-
-
35248867156
-
Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: Role of nuclear factor-kappaB, heat shock factor 1, and Akt
-
Zingarelli B, Hake PW, Mangeshkar P, et al. Diverse cardioprotective signaling mechanisms of peroxisome proliferator-activated receptor-gamma ligands, 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone, in reperfusion injury: Role of nuclear factor-kappaB, heat shock factor 1, and Akt. Shock. 2007;28:554-563.
-
(2007)
Shock
, vol.28
, pp. 554-563
-
-
Zingarelli, B.1
Hake, P.W.2
Mangeshkar, P.3
-
40
-
-
33847054264
-
Attenuation of reperfusion lung injury and apoptosis by A2A adenosine receptor activation is associated with modulation of Bcl-2 and Bax expression and activation of extracellular signal-regulated kinases
-
Rivo J, Zeira E, Galun E, Einav S, Linden J, Matot I. Attenuation of reperfusion lung injury and apoptosis by A2A adenosine receptor activation is associated with modulation of Bcl-2 and Bax expression and activation of extracellular signal-regulated kinases. Shock. 2007;27: 266-273.
-
(2007)
Shock
, vol.27
, pp. 266-273
-
-
Rivo, J.1
Zeira, E.2
Galun, E.3
Einav, S.4
Linden, J.5
Matot, I.6
-
41
-
-
0034770987
-
Role of the complement system in ischaemic heart disease: Potential for pharmacological intervention
-
Shernan SK, Collard CD. Role of the complement system in ischaemic heart disease: Potential for pharmacological intervention. BioDrugs. 2001;15:595-607.
-
(2001)
Bio Drugs
, vol.15
, pp. 595-607
-
-
Shernan, S.K.1
Collard, C.D.2
-
42
-
-
0035497740
-
Neutralization of interleukin-1beta in the acute phase ofmyocardial infarction promotes the progression of left ventricular remodeling
-
HwangMW,Matsumori A, Furukawa Y, et al.Neutralization of interleukin-1beta in the acute phase ofmyocardial infarction promotes the progression of left ventricular remodeling. JAmColl Cardiol. 2001;38:1546-1553.
-
(2001)
JAmColl Cardiol
, vol.38
, pp. 1546-1553
-
-
Hwang, M.W.1
Matsumori, A.2
Furukawa, Y.3
-
44
-
-
46749144616
-
Interleukin-1 receptor type i signaling critically regulates infarct healing and cardiac remodeling
-
BujakM, Dobaczewski M, Chatila K, et al. Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling. AmJ Pathol. 2008;173:57-67.
-
(2008)
AmJ Pathol
, vol.173
, pp. 57-67
-
-
Bujak, M.1
Dobaczewski, M.2
Chatila, K.3
-
45
-
-
42449145243
-
Antioxidant gene therapy for cardiovascular disease: Current status and future perspectives
-
Levonen AL, Vahakangas E, Koponen JK, Yla-Herttuala S. Antioxidant gene therapy for cardiovascular disease: Current status and future perspectives. Circulation. 2008;117:2142-2150.
-
(2008)
Circulation
, vol.117
, pp. 2142-2150
-
-
Levonen, A.L.1
Vahakangas, E.2
Koponen, J.K.3
Yla-Herttuala, S.4
-
46
-
-
33746698337
-
Brain cooling causes attenuation of cerebral oxidative stress, systemic inflammation, activated coagulation, and tissue ischemia/injury during heatstroke
-
Hsu SF, Niu KC, Lin CL, Lin MT. Brain cooling causes attenuation of cerebral oxidative stress, systemic inflammation, activated coagulation, and tissue ischemia/injury during heatstroke. Shock. 2006;26:210-220.
-
(2006)
Shock
, vol.26
, pp. 210-220
-
-
Hsu, S.F.1
Niu, K.C.2
Lin, C.L.3
Lin, M.T.4
-
47
-
-
0037383432
-
The mitochondrial permeability transition pore: Its fundamental role in mediating cell death during ischaemia and reperfusion
-
Hausenloy DJ, Yellon DM. The mitochondrial permeability transition pore: Its fundamental role in mediating cell death during ischaemia and reperfusion. JMol Cell Cardiol. 2003;35:339-341.
-
(2003)
J. Mol Cell Cardiol
, vol.35
, pp. 339-341
-
-
Hausenloy, D.J.1
Yellon, D.M.2
-
48
-
-
77950950851
-
Apoptosis as amechanism for the elimination of cardiomyocytes after acutemyocardial infarction
-
PrechM,Marszalek A, Schroder J, et al. Apoptosis as amechanism for the elimination of cardiomyocytes after acutemyocardial infarction. Am J Cardiol. 2010;105:1240-1245.
-
(2010)
Am J Cardiol
, vol.105
, pp. 1240-1245
-
-
Prech, M.1
Marszalek, A.2
Schroder, J.3
-
49
-
-
80055121590
-
Acute myocardial infarction in rats
-
Wu Y, Yin X, Wijaya C, Huang MH, McConnell BK. Acute myocardial infarction in rats. J Vis Exp. 2011;48:e2464.
-
(2011)
J Vis Exp
, vol.48
-
-
Wu, Y.1
Yin, X.2
Wijaya, C.3
Huang, M.H.4
McConnell, B.K.5
-
50
-
-
45549098685
-
Molecular mechanisms and pathophysiology of necrotic cell death
-
Vanlangenakker N, Vanden Berghe T, Krysko DV, Festjens N, Vandenabeele P. Molecular mechanisms and pathophysiology of necrotic cell death. CurrMolMed. 2008;8:207-220.
-
(2008)
Curr Mol Med
, vol.8
, pp. 207-220
-
-
Vanlangenakker, N.1
Vanden Berghe, T.2
Krysko, D.V.3
Festjens, N.4
Vandenabeele, P.5
-
51
-
-
79957440231
-
Regulation of death receptor-induced apoptosis induced via cd95fas and other death receptors
-
Lavrik IN. [Regulation of death receptor-induced apoptosis induced via CD95/FAS and other death receptors].Mol Biol (Mosk). 2011;45:173-179.
-
(2011)
Mol Biol (Mosk
, vol.45
, pp. 173-179
-
-
Lavrik, I.N.1
-
52
-
-
33744981148
-
Gamma secretase-mediated notch signaling worsens brain damage and functional outcome in ischemic stroke
-
Arumugam TV, Chan SL, Jo DG, et al. Gamma secretase-mediated Notch signaling worsens brain damage and functional outcome in ischemic stroke. Nat Med. 2006;12:621-623.
-
(2006)
Nat Med
, vol.12
, pp. 621-623
-
-
Arumugam, T.V.1
Chan, S.L.2
Jo, D.G.3
-
53
-
-
0032701642
-
Toll4 (TLR4) expression in cardiacmyocytes in normal and failing myocardium
-
Frantz S, Kobzik L, Kim YD, et al. Toll4 (TLR4) expression in cardiacmyocytes in normal and failing myocardium. J Clin Invest. 1999;104:271-280.
-
(1999)
J Clin Invest
, vol.104
, pp. 271-280
-
-
Frantz, S.1
Kobzik, L.2
Kim, Y.D.3
-
54
-
-
77954675751
-
Inhibition of PI3K/AKT andMAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer
-
Roy SK, Srivastava RK, Shankar S. Inhibition of PI3K/AKT andMAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer. J Mol Signal. 2010;5:10.
-
(2010)
J Mol Signal
, vol.5
, pp. 10
-
-
Roy, S.K.1
Srivastava, R.K.2
Shankar, S.3
-
55
-
-
79953716236
-
Toll-like receptor and its roles in myocardial ischemic/reperfusion injury
-
Fang Y, Hu J. Toll-like receptor and its roles in myocardial ischemic/reperfusion injury. Med Sci Monit. 2011;17:RA100-RA109.
-
(2011)
Med Sci Monit
, vol.17
-
-
Fang, Y.1
Hu, J.2
-
56
-
-
77957252647
-
The IKK complex, a central regulator of NF-kappaB activation
-
Israel A. The IKK complex, a central regulator of NF-kappaB activation. Cold Spring Harb Perspect Biol. 2010;2:a000158.
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
-
-
Israel, A.1
-
57
-
-
44449085285
-
Lipopolysaccharide-induced myocardial protection against ischaemia/ reperfusion injury is mediated through a PI3K/Akt-dependent mechanism
-
Ha T, Hua F, Liu X, et al. Lipopolysaccharide-induced myocardial protection against ischaemia/ reperfusion injury is mediated through a PI3K/Akt-dependent mechanism. Cardiovasc Res. 2008;78:546-553.
-
(2008)
Cardiovasc Res
, vol.78
, pp. 546-553
-
-
Ha, T.1
Hua, F.2
Liu, X.3
-
58
-
-
33747178729
-
Inhibition of Toll-like receptor 4 with eritoran attenuates myocardial ischemia-reperfusion injury
-
Shimamoto A, Chong AJ, Yada M, et al. Inhibition of Toll-like receptor 4 with eritoran attenuates myocardial ischemia-reperfusion injury. Circulation. 2006;114:I270-I274.
-
(2006)
Circulation
, vol.114
-
-
Shimamoto, A.1
Chong, A.J.2
Yada, M.3
-
59
-
-
0345599171
-
Toll-like receptor-2 modulates ventricular remodeling aftermyocardial infarction
-
Shishido T, Nozaki N, Yamaguchi S, et al. Toll-like receptor-2 modulates ventricular remodeling aftermyocardial infarction. Circulation. 2003;108:2905-2910.
-
(2003)
Circulation
, vol.108
, pp. 2905-2910
-
-
Shishido, T.1
Nozaki, N.2
Yamaguchi, S.3
-
60
-
-
34247363161
-
Toll-like receptors 2-deficientmice are protected against postischemic coronary endothelial dysfunction
-
Favre J,Musette P,Douin-EchinardV, et al.Toll-like receptors 2-deficientmice are protected against postischemic coronary endothelial dysfunction. ArteriosclerThromb Vasc Biol. 2007;27:1064-1071.
-
(2007)
ArteriosclerThromb Vasc Biol
, vol.27
, pp. 1064-1071
-
-
Favre, J.1
Musette, P.2
Douin-Echinard, V.3
-
61
-
-
74549178528
-
Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-Toll-like receptor-2 antibody
-
Arslan F, Smeets MB, O'Neill LA, et al. Myocardial ischemia/reperfusion injury is mediated by leukocytic toll-like receptor-2 and reduced by systemic administration of a novel anti-Toll-like receptor-2 antibody. Circulation. 2010;121:80-90.
-
(2010)
Circulation
, vol.121
, pp. 80-90
-
-
Arslan, F.1
Smeets, M.B.2
O'Neill, L.A.3
-
62
-
-
77957231123
-
Toll-like receptor 2 signaling triggers fatal arrhythmias upon myocardial ischemia-reperfusion
-
Mersmann J, Koch A, Tran N, et al. Toll-like receptor 2 signaling triggers fatal arrhythmias upon myocardial ischemia-reperfusion. Crit CareMed. 2010;38:1927-1932.
-
(2010)
Crit CareMed
, vol.38
, pp. 1927-1932
-
-
Mersmann, J.1
Koch, A.2
Tran, N.3
-
63
-
-
0035895913
-
Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiacmyocytes
-
Frantz S, Kelly RA, Bourcier T. Role of TLR-2 in the activation of nuclear factor kappaB by oxidative stress in cardiacmyocytes. J Biol Chem. 2001;276:5197-5203.
-
(2001)
J Biol Chem
, vol.276
, pp. 5197-5203
-
-
Frantz, S.1
Kelly, R.A.2
Bourcier, T.3
-
64
-
-
33947109614
-
Toll-like receptor 2 activation by bacterial peptidoglycan-associated lipoprotein activates cardiomyocyte inflammation and contractile dysfunction
-
Zhu X, Bagchi A, ZhaoH, et al. Toll-like receptor 2 activation by bacterial peptidoglycan-associated lipoprotein activates cardiomyocyte inflammation and contractile dysfunction. Crit Care Med. 2007;35:886-892.
-
(2007)
Crit Care Med
, vol.35
, pp. 886-892
-
-
Zhu, X.1
Zhaoh, B.A.2
-
65
-
-
27744589750
-
Blocking the MyD88-dependent pathway protects the myocardium from ischemia/reperfusion injury in rat hearts
-
Hua F, Ha T, Ma J, et al. Blocking the MyD88-dependent pathway protects the myocardium from ischemia/reperfusion injury in rat hearts. Biochem Biophys Res Commun. 2005;338:1118-1125.
-
(2005)
Biochem Biophys Res Commun
, vol.338
, pp. 1118-1125
-
-
Hua, F.1
Ha, T.2
Ma, J.3
-
66
-
-
54049149858
-
Innate immune adaptor MyD88 mediates neutrophil recruitment and myocardial injury after ischemia-reperfusion in mice
-
Feng Y, Zhao H, Xu X, et al. Innate immune adaptor MyD88 mediates neutrophil recruitment and myocardial injury after ischemia-reperfusion in mice. Am J Physiol Heart Circ Physiol. 2008;295:H1311-H1318.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Feng, Y.1
Zhao, H.2
Xu, X.3
-
67
-
-
58149500135
-
Toll-like receptor signaling: A criticalmodulator of cell survival and ischemic injury in the heart
-
Chao W. Toll-like receptor signaling: A criticalmodulator of cell survival and ischemic injury in the heart. Am J Physiol Heart Circ Physiol. 2009;296:1-12.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
, pp. 1-12
-
-
Chao, W.1
-
68
-
-
77749291737
-
Innate immunity mediates myocardial preconditioning through Toll-like receptor 2 and TIRAP-dependent signaling pathways
-
Dong JW, Vallejo JG, Tzeng HP,Thomas JA, Mann DL. Innate immunity mediates myocardial preconditioning through Toll-like receptor 2 and TIRAP-dependent signaling pathways. Am J Physiol Heart Circ Physiol. 2010;298:H1079-H1087.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
-
-
Dong, J.W.1
Vallejo, J.G.2
Tzeng, H.P.3
Thomas, J.A.4
Mann, D.L.5
-
69
-
-
20544442905
-
Alarmins: Chemotactic activators of immune responses
-
Oppenheim JJ, Yang D. Alarmins: Chemotactic activators of immune responses. Curr Opin Immunol. 2005;17:359-365.
-
(2005)
Curr Opin Immunol
, vol.17
, pp. 359-365
-
-
Oppenheim, J.J.1
Yang, D.2
-
70
-
-
79958760634
-
Lipopolysaccharide pretreatment protects against ischemia/ reperfusion injury via increase of HSP70 and inhibition of NF-kappaB
-
Yao YW, Zhang GH, Zhang YY, et al. Lipopolysaccharide pretreatment protects against ischemia/ reperfusion injury via increase of HSP70 and inhibition of NF-kappaB. Cell Stress Chaperones. 2011;16:287-296.
-
(2011)
Cell Stress Chaperones
, vol.16
, pp. 287-296
-
-
Yao, Y.W.1
Zhang, G.H.2
Zhang, Y.Y.3
-
71
-
-
77249087063
-
Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin
-
Schneider-Poetsch T, Ju J, Eyler DE, et al. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nat Chem Biol. 2010;6:209-217.
-
(2010)
Nat Chem Biol
, vol.6
, pp. 209-217
-
-
Schneider-Poetsch, T.1
Ju, J.2
Eyler, D.E.3
-
72
-
-
33749338467
-
MyD88 and NOS2 are essential for Toll-like receptor 4-mediated survival effect in cardiomyocytes
-
Zhu X, ZhaoH, Graveline AR, et al.MyD88 and NOS2 are essential for Toll-like receptor 4-mediated survival effect in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2006;291:H1900-H1909.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
-
-
Zhu, X.1
Zhaoh Graveline, A.R.2
-
73
-
-
0036169559
-
Ischemic preconditioning upregulates inducible nitric oxide synthase in cardiacmyocyte
-
Wang Y, Guo Y, Zhang SX, et al. Ischemic preconditioning upregulates inducible nitric oxide synthase in cardiacmyocyte. JMol Cell Cardiol. 2002;34:5-15.
-
(2002)
J Mol Cell Cardiol
, vol.34
, pp. 5-15
-
-
Wang, Y.1
Guo, Y.2
Zhang, S.X.3
-
74
-
-
11144344931
-
Nitric oxide inhibits myocardial apoptosis by preventing caspase-3 activity via S-nitrosylation
-
Maejima Y, Adachi S, Morikawa K, Ito H, Isobe M. Nitric oxide inhibits myocardial apoptosis by preventing caspase-3 activity via S-nitrosylation. JMol Cell Cardiol. 2005;38:163-174.
-
(2005)
J Mol Cell Cardiol
, vol.38
, pp. 163-174
-
-
Maejima, Y.1
Adachi, S.2
Morikawa, K.3
Ito, H.4
Isobe, M.5
-
75
-
-
34548583437
-
Innateimmunity,macrophage activation, and atherosclerosis
-
Yan ZQ,HanssonGK. Innateimmunity,macrophage activation, and atherosclerosis.Immunol Rev. 2007;219:187-203.
-
(2007)
Immunol Rev
, vol.219
, pp. 187-203
-
-
Yan, Z.Q.1
Hansson, G.K.2
-
76
-
-
52149089441
-
Vascular cell responsiveness to Toll-like receptor ligands in carotid atheroma
-
Erridge C, Burdess A, Jackson AJ, et al. Vascular cell responsiveness to Toll-like receptor ligands in carotid atheroma. Eur J Clin Invest. 2008;38:713-720.
-
(2008)
Eur J Clin Invest
, vol.38
, pp. 713-720
-
-
Erridge, C.1
Burdess, A.2
Jackson, A.J.3
-
77
-
-
33645064033
-
Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease
-
Ott SJ, ElMokhtari NE,Musfeldt M, et al.Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease. Circulation. 2006;113:929-937.
-
(2006)
Circulation
, vol.113
, pp. 929-937
-
-
Ott, S.J.1
El Mokhtari, N.E.2
Musfeldt, M.3
-
78
-
-
0037099477
-
Significance of peptidoglycan, a proinflammatory bacterial antigen in atherosclerotic arteries and its association with vulnerable plaques
-
Laman JD, Schoneveld AH, Moll FL, van Meurs M, Pasterkamp G. Significance of peptidoglycan, a proinflammatory bacterial antigen in atherosclerotic arteries and its association with vulnerable plaques. AmJ Cardiol. 2002;90:119-123.
-
(2002)
AmJ Cardiol
, vol.90
, pp. 119-123
-
-
Laman, J.D.1
Schoneveld, A.H.2
Moll, F.L.3
Van Meurs, M.4
Pasterkamp, G.5
-
79
-
-
2542498855
-
Autoimmune and inflammatory mechanisms in atherosclerosis
-
Wick G, Knoflach M, Xu Q. Autoimmune and inflammatory mechanisms in atherosclerosis. Annu Rev Immunol. 2004;22:361-403.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 361-403
-
-
Wick, G.1
Knoflach, M.2
Xu, Q.3
-
80
-
-
0036038494
-
Chlamydia pneumoniae and atherosclerosis - What we know and what we don't
-
Ngeh J, Anand V, Gupta S. Chlamydia pneumoniae and atherosclerosis - What we know and what we don't. ClinMicrobiol Infect. 2002;8:2-13.
-
(2002)
ClinMicrobiol Infect
, vol.8
, pp. 2-13
-
-
Ngeh, J.1
Anand, V.2
Gupta, S.3
-
81
-
-
58149201571
-
Chlamydia pneumoniae-induced foam cell formation requiresMyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation
-
Chen S, Sorrentino R, Shimada K, et al. Chlamydia pneumoniae-induced foam cell formation requiresMyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation. J Immunol. 2008;181:7186-7193.
-
(2008)
J Immunol
, vol.181
, pp. 7186-7193
-
-
Chen, S.1
Sorrentino, R.2
Shimada, K.3
-
82
-
-
33846847536
-
Chlamydia pneumoniae-inducedmacrophage foam cell formation ismediated by Toll-like receptor 2
-
Cao F, Castrillo A, Tontonoz P, Re F, Byrne GI. Chlamydia pneumoniae-inducedmacrophage foam cell formation ismediated by Toll-like receptor 2. Infect Immun. 2007;75:753-759.
-
(2007)
Infect Immun
, vol.75
, pp. 753-759
-
-
Cao, F.1
Castrillo, A.2
Tontonoz, P.3
Re, F.4
Byrne, G.I.5
-
83
-
-
3242710174
-
Lack of Toll-like receptor 4 ormyeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype inmice deficient in apolipoprotein e
-
MichelsenKS,WongMH,Shah PK, et al. Lack of Toll-like receptor 4 ormyeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype inmice deficient in apolipoprotein E. Proc Natl Acad Sci U S A. 2004;101:10679-10684.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10679-10684
-
-
Michelsen, K.S.1
Wong, M.H.2
Shah, P.K.3
-
84
-
-
0037066041
-
Expression of toll-like receptors in human atherosclerotic lesions: A possible pathway for plaque activation
-
Edfeldt K, Swedenborg J, Hansson GK, Yan ZQ. Expression of toll-like receptors in human atherosclerotic lesions: A possible pathway for plaque activation. Circulation. 2002;105: 1158-1161.
-
(2002)
Circulation
, vol.105
, pp. 1158-1161
-
-
Edfeldt, K.1
Swedenborg, J.2
Hansson, G.K.3
Yan, Z.Q.4
-
85
-
-
77956929099
-
Important aspects of Toll-like receptors, ligands and their signaling pathways
-
Chang ZL. Important aspects of Toll-like receptors, ligands and their signaling pathways. Inflamm Res. 2010;59:791-808.
-
(2010)
Inflamm Res
, vol.59
, pp. 791-808
-
-
Chang, Z.L.1
-
86
-
-
79953295363
-
Oxidized lowdensity lipoprotein induces bone morphogenetic protein-2 in coronary artery endothelial cells via Toll-like receptors 2 and 4
-
Su X, Ao L, Shi Y, Johnson TR, Fullerton DA,Meng X. Oxidized lowdensity lipoprotein induces bone morphogenetic protein-2 in coronary artery endothelial cells via Toll-like receptors 2 and 4. J Biol Chem. 2011;286:12213-12220.
-
(2011)
J Biol Chem
, vol.286
, pp. 12213-12220
-
-
Su, X.1
Ao, L.2
Shi, Y.3
Johnson, T.R.4
Fullerton Dameng, X.5
-
87
-
-
35848957934
-
Differential expression of Toll-like receptor 2 (TLR2) and responses to TLR2 ligands between human andmurine vascular endothelial cells
-
Shuang C,Wong MH, Schulte DJ, Arditi M,Michelsen KS. Differential expression of Toll-like receptor 2 (TLR2) and responses to TLR2 ligands between human andmurine vascular endothelial cells. J Endotoxin Res. 2007;13:281-296.
-
(2007)
J Endotoxin Res
, vol.13
, pp. 281-296
-
-
Shuang, C.1
Wong, M.H.2
Schulte, D.J.3
Arditi, M.4
Michelsen, K.S.5
-
88
-
-
66349115622
-
Emerging role of Toll-like receptors in atherosclerosis
-
Curtiss LK, Tobias PS. Emerging role of Toll-like receptors in atherosclerosis. J Lipid Res. 2009;50 (Suppl):S340-S345.
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Curtiss, L.K.1
Tobias, P.S.2
-
89
-
-
0034123135
-
Differential expression and regulation of Toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
-
Muzio M, Bosisio D, Polentarutti N, et al. Differential expression and regulation of Toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells. J Immunol. 2000;164:5998-6004.
-
(2000)
J Immunol
, vol.164
, pp. 5998-6004
-
-
Muzio, M.1
Bosisio, D.2
Polentarutti, N.3
-
90
-
-
0035903288
-
Subsets of human dendritic cell precursors express different Toll-like receptors and respond to differentmicrobial antigens
-
Kadowaki N, Ho S, Antonenko S, et al. Subsets of human dendritic cell precursors express different Toll-like receptors and respond to differentmicrobial antigens. J ExpMed. 2001;194:863-869.
-
(2001)
J ExpMed
, vol.194
, pp. 863-869
-
-
Kadowaki, N.1
Ho, S.2
Antonenko, S.3
-
91
-
-
0035164253
-
Regulation of Toll-like receptors in humanmonocytes and dendritic cells
-
Visintin A,Mazzoni A, Spitzer JH,WyllieDH,Dower SK, SegalDM. Regulation of Toll-like receptors in humanmonocytes and dendritic cells. J Immunol. 2001;166:249-255.
-
(2001)
J Immunol
, vol.166
, pp. 249-255
-
-
Visintin, A.1
Mazzoni, A.2
Spitzer, J.H.3
Wyllie, D.H.4
Dower, S.K.5
Segal, D.M.6
-
92
-
-
0036570169
-
Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
-
Hornung V, Rothenfusser S, Britsch S, et al. Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol. 2002;168:4531-4537.
-
(2002)
J Immunol
, vol.168
, pp. 4531-4537
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
-
93
-
-
33644867555
-
Increased expression of Toll like receptor 4 on peripheralblood mononuclear cells in patients with coronary arteriosclerosis disease
-
Geng HL, Lu HQ, Zhang LZ, et al. Increased expression of Toll like receptor 4 on peripheralblood mononuclear cells in patients with coronary arteriosclerosis disease. Clin Exp Immunol. 2006;143:269-273.
-
(2006)
Clin Exp Immunol
, vol.143
, pp. 269-273
-
-
Geng, H.L.1
Lu, H.Q.2
Zhang, L.Z.3
-
94
-
-
77049098321
-
High expression level of Toll-like receptor 2 on monocytes is an important risk factor for arteriosclerotic disease
-
Kuwahata S, Fujita S, Orihara K, et al. High expression level of Toll-like receptor 2 on monocytes is an important risk factor for arteriosclerotic disease. Atherosclerosis. 2010;209:248-254.
-
(2010)
Atherosclerosis
, vol.209
, pp. 248-254
-
-
Kuwahata, S.1
Fujita, S.2
Orihara, K.3
-
95
-
-
25144505907
-
Characterization of the expression of TLR2 (Toll-like receptor 2) and TLR4 on circulating monocytes in coronary artery disease
-
Ashida K, Miyazaki K, Takayama E, et al. Characterization of the expression of TLR2 (Toll-like receptor 2) and TLR4 on circulating monocytes in coronary artery disease. J Atheroscler Thromb. 2005;12:53-60.
-
(2005)
J Atheroscler Thromb
, vol.12
, pp. 53-60
-
-
Ashida, K.1
Miyazaki, K.2
Takayama, E.3
-
96
-
-
44349151815
-
Monocyte Toll-like receptor 2 and 4 responses and expression following percutaneous coronary intervention: Association with lesion stenosis and fractional flow reserve
-
Versteeg D, Hoefer IE, Schoneveld AH, et al.Monocyte Toll-like receptor 2 and 4 responses and expression following percutaneous coronary intervention: Association with lesion stenosis and fractional flow reserve. Heart. 2008;94:770-776.
-
(2008)
Heart
, vol.94
, pp. 770-776
-
-
Versteeg, D.1
Hoefer, I.E.2
Schoneveld, A.H.3
-
97
-
-
33745946535
-
Oxidized low-density lipoprotein correlates positively with Toll-like receptor 2 and interferon regulatory factor-1 and inversely with superoxide dismutase-1 expression: Studies in hypercholesterolemic swine and THP-1 cells
-
Holvoet P,Davey PC,De KeyzerD, et al. Oxidized low-density lipoprotein correlates positively with Toll-like receptor 2 and interferon regulatory factor-1 and inversely with superoxide dismutase-1 expression: Studies in hypercholesterolemic swine and THP-1 cells. ArteriosclerThromb Vasc Biol. 2006;26:1558-1565.
-
(2006)
ArteriosclerThromb Vasc Biol
, vol.26
, pp. 1558-1565
-
-
Holvoet, P.1
Davey, P.C.2
De Keyzer, D.3
-
98
-
-
4043058031
-
Advanced glycation end products and vascular inflammation: Implications for accelerated atherosclerosis in diabetes
-
BastaG, Schmidt AM,De Caterina R. Advanced glycation end products and vascular inflammation: Implications for accelerated atherosclerosis in diabetes. Cardiovasc Res. 2004;63:582-592.
-
(2004)
Cardiovasc Res
, vol.63
, pp. 582-592
-
-
Basta, G.1
Schmidt, A.M.2
De Caterina, R.3
-
99
-
-
33644872836
-
Inflammation and cardiovascular diseasemechanisms
-
Libby P. Inflammation and cardiovascular diseasemechanisms.AmJ ClinNutr. 2006;83:456S-460S.
-
(2006)
AmJ ClinNutr
, vol.83
-
-
Libby, P.1
-
100
-
-
57549113882
-
Advanced glycation end-product of low density lipoprotein activates the Toll-like 4 receptor pathway implications for diabetic atherosclerosis
-
Hodgkinson CP, Laxton RC, Patel K, Ye S. Advanced glycation end-product of low density lipoprotein activates the Toll-like 4 receptor pathway implications for diabetic atherosclerosis. Arterioscler Thromb Vasc Biol. 2008;28:2275-2281.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 2275-2281
-
-
Hodgkinson, C.P.1
Laxton, R.C.2
Patel, K.3
Ye, S.4
-
102
-
-
75649087741
-
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
-
Stewart CR, Stuart LM, Wilkinson K, et al. CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat Immunol. 2010;11:155-161.
-
(2010)
Nat Immunol
, vol.11
, pp. 155-161
-
-
Stewart, C.R.1
Stuart, L.M.2
Wilkinson, K.3
-
103
-
-
0142124855
-
Oxidized phospholipids as modulators of inflammation in atherosclerosis
-
Leitinger N. Oxidized phospholipids as modulators of inflammation in atherosclerosis. Curr Opin Lipidol. 2003;14:421-30.
-
(2003)
Curr Opin Lipidol
, vol.14
, pp. 421-430
-
-
Leitinger, N.1
-
104
-
-
24744462348
-
The role of natural antibodies in atherogenesis
-
Binder CJ, Shaw PX, Chang MK, et al.The role of natural antibodies in atherogenesis. J Lipid Res. 2005;46:1353-1363.
-
(2005)
J Lipid Res
, vol.46
, pp. 1353-1363
-
-
Binder, C.J.1
Shaw, P.X.2
Chang, M.K.3
-
105
-
-
21444445056
-
A role for oxidized phospholipids in atherosclerosis
-
Berliner JA, Watson AD. A role for oxidized phospholipids in atherosclerosis. N Engl J Med. 2005;353:9-11.
-
(2005)
N Engl J Med
, vol.353
, pp. 9-11
-
-
Berliner, J.A.1
Watson, A.D.2
-
106
-
-
21444445056
-
A role for oxidized phospholipids in atherosclerosis
-
Berliner JA, Watson AD. A role for oxidized phospholipids in atherosclerosis. N Engl J Med. 2005;353:9-11.
-
(2005)
N Engl J Med
, vol.353
, pp. 9-11
-
-
Berliner, J.A.1
Watson, A.D.2
-
107
-
-
84863495004
-
The role of oxidized phospholipids in atherosclerosis
-
Berliner JA, Leitinger N, Tsimikas S. The role of oxidized phospholipids in atherosclerosis. J Lipid Res. 2009;50 (Suppl):S207-S212.
-
(2009)
J Lipid Res
, vol.50
, Issue.SUPPL.
-
-
Berliner, J.A.1
Leitinger, N.2
Tsimikas, S.3
-
108
-
-
44849094277
-
Cholesteryl ester hydroperoxides are biologically active components of minimally oxidized low density lipoprotein
-
Harkewicz R, Hartvigsen K, Almazan F, Dennis EA, Witztum JL, Miller YI. Cholesteryl ester hydroperoxides are biologically active components of minimally oxidized low density lipoprotein. J Biol Chem. 2008;283:10241-10251.
-
(2008)
J Biol Chem
, vol.283
, pp. 10241-10251
-
-
Harkewicz, R.1
Hartvigsen, K.2
Almazan, F.3
Dennis, E.A.4
Witztum, J.L.5
Miller, Y.I.6
-
109
-
-
20144385204
-
Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages
-
Miller YI, Viriyakosol S,Worrall DS, Boullier A, Butler S, Witztum JL. Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages. ArteriosclerThromb Vasc Biol. 2005;25:1213-1219.
-
(2005)
ArteriosclerThromb Vasc Biol
, vol.25
, pp. 1213-1219
-
-
Miller, Y.I.1
Viriyakosol, S.2
Worrall, D.S.3
Boullier, A.4
Butler, S.5
Witztum, J.L.6
-
110
-
-
59849086158
-
Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: Toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2
-
21p following 8
-
Bae YS, Lee JH, Choi SH, et al.Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: Toll-like receptor 4- And spleen tyrosine kinase-dependent activation of NADPH oxidase 2. Circ Res. 2009;104:210-218, 21p following 8.
-
(2009)
Circ Res
, vol.104
, pp. 210-218
-
-
Bae, Y.S.1
Lee, J.H.2
Choi, S.H.3
-
111
-
-
67650266902
-
Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake
-
Choi SH, Harkewicz R, Lee JH, et al. Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake. Circ Res. 2009;104:1355-1363.
-
(2009)
Circ Res
, vol.104
, pp. 1355-1363
-
-
Choi, S.H.1
Harkewicz, R.2
Lee, J.H.3
-
112
-
-
0141429953
-
Actin polymerization in macrophages in response to oxidized LDL and apoptotic cells: Role of 12/15-lipoxygenase and phosphoinositide 3-kinase
-
Miller YI, Worrall DS, Funk CD, Feramisco JR, Witztum JL. Actin polymerization in macrophages in response to oxidized LDL and apoptotic cells: Role of 12/15-lipoxygenase and phosphoinositide 3-kinase.Mol Biol Cell. 2003;14:4196-4206.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 4196-4206
-
-
Miller, Y.I.1
Worrall, D.S.2
Funk, C.D.3
Feramisco, J.R.4
Witztum, J.L.5
-
113
-
-
10644254917
-
Increased expression of the DNA-binding cytokine HMGB1 in human atherosclerotic lesions: Role of activated macrophages and cytokines
-
Kalinina N, Agrotis A, Antropova Y, et al. Increased expression of the DNA-binding cytokine HMGB1 in human atherosclerotic lesions: Role of activated macrophages and cytokines. Arterioscler Thromb Vasc Biol. 2004;24:2320-2325.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 2320-2325
-
-
Kalinina, N.1
Agrotis, A.2
Antropova, Y.3
-
114
-
-
48949097129
-
Functional Toll-like receptor 4 mutations modulate the response to fibrinogen
-
Hodgkinson CP, Patel K, Ye S. Functional Toll-like receptor 4 mutations modulate the response to fibrinogen. Thromb Haemost. 2008;100:301-307.
-
(2008)
Thromb Haemost
, vol.100
, pp. 301-307
-
-
Hodgkinson, C.P.1
Patel, K.2
Ye, S.3
-
115
-
-
0141844653
-
Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids
-
Lee JY, Ye J, Gao Z, et al. Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids. J Biol Chem. 2003;278:37041-37051.
-
(2003)
J Biol Chem
, vol.278
, pp. 37041-37051
-
-
Lee, J.Y.1
Ye, J.2
Gao, Z.3
-
116
-
-
17844391306
-
Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4
-
Weatherill AR, Lee JY, Zhao L, Lemay DG, Youn HS, Hwang DH. Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4. J Immunol. 2005;174:5390-5397.
-
(2005)
J Immunol
, vol.174
, pp. 5390-5397
-
-
Weatherill, A.R.1
Lee, J.Y.2
Zhao, L.3
Lemay, D.G.4
Youn, H.S.5
Hwang, D.H.6
-
117
-
-
77954697249
-
Anti-Inflammatory pro-resolving derivatives of omega-3 and omega-6 polyunsaturated fatty acids
-
Nowak JZ. [Anti-inflammatory pro-resolving derivatives of omega-3 and omega-6 polyunsaturated fatty acids]. Postepy HigMed Dosw (Online). 2010;64:115-132.
-
(2010)
Postepy HigMed Dosw (Online
, vol.64
, pp. 115-132
-
-
Nowak, J.Z.1
-
118
-
-
67650502739
-
Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease
-
Midwood K, Sacre S, Piccinini AM, et al. Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease. Nat Med. 2009;15: 774-780.
-
(2009)
Nat Med
, vol.15
, pp. 774-780
-
-
Midwood, K.1
Sacre, S.2
Piccinini, A.M.3
-
119
-
-
30744451472
-
Glycosaminoglycans and their proteoglycans: Host-associated molecular patterns for initiation andmodulation of inflammation
-
Taylor KR, Gallo RL. Glycosaminoglycans and their proteoglycans: Host-associated molecular patterns for initiation andmodulation of inflammation. FASEB J. 2006;20:9-22.
-
(2006)
FASEB J
, vol.20
, pp. 9-22
-
-
Taylor, K.R.1
Gallo, R.L.2
-
120
-
-
27644568878
-
Modulation of atherosclerosis in mice by Toll-like receptor 2
-
Mullick AE, Tobias PS, Curtiss LK. Modulation of atherosclerosis in mice by Toll-like receptor 2. J Clin Invest. 2005;115:3149-3156.
-
(2005)
J Clin Invest
, vol.115
, pp. 3149-3156
-
-
Mullick, A.E.1
Tobias, P.S.2
Curtiss, L.K.3
-
121
-
-
0035910010
-
Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL
-
Xu XH, Shah PK, Faure E, et al. Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL. Circulation. 2001;104:3103-3108.
-
(2001)
Circulation
, vol.104
, pp. 3103-3108
-
-
Xu, X.H.1
Shah, P.K.2
Faure, E.3
-
122
-
-
39549120661
-
Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events
-
Mullick AE, Soldau K, Kiosses WB, Bell TA 3rd, Tobias PS, Curtiss LK. Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic events. J ExpMed. 2008;205:373-383.
-
(2008)
J ExpMed
, vol.205
, pp. 373-383
-
-
Mullick, A.E.1
Soldau, K.2
Kiosses, W.B.3
Bell Iii, T.A.4
Tobias, P.S.5
Curtiss, L.K.6
-
123
-
-
73349128100
-
Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis
-
Monaco C, Gregan SM, Navin TJ, Foxwell BM, Davies AH, Feldmann M. Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosis. Circulation. 2009;120:2462-2469.
-
(2009)
Circulation
, vol.120
, pp. 2462-2469
-
-
Monaco, C.1
Gregan, S.M.2
Navin, T.J.3
Foxwell, B.M.4
Davies, A.H.5
Feldmann, M.6
-
124
-
-
38049029104
-
Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids
-
Liu X, Ukai T, Yumoto H, et al. Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids. Atherosclerosis. 2008;196:146-154.
-
(2008)
Atherosclerosis
, vol.196
, pp. 146-154
-
-
Liu, X.1
Ukai, T.2
Yumoto, H.3
-
125
-
-
58149381764
-
Toll-like receptor 2 mediates apolipoprotein CIII-induced monocyte activation
-
Kawakami A, Osaka M, Aikawa M, et al. Toll-like receptor 2 mediates apolipoprotein CIII-induced monocyte activation. Circ Res. 2008;103:1402-1409.
-
(2008)
Circ Res
, vol.103
, pp. 1402-1409
-
-
Kawakami, A.1
Osaka, M.2
Aikawa, M.3
-
126
-
-
13444280215
-
CD36 is a sensor of diacylglycerides
-
Hoebe K, Georgel P, Rutschmann S, et al. CD36 is a sensor of diacylglycerides. Nature. 2005;433:523-527.
-
(2005)
Nature
, vol.433
, pp. 523-527
-
-
Hoebe, K.1
Georgel, P.2
Rutschmann, S.3
-
127
-
-
33847183077
-
Cooperation of Toll-like receptor signals in innate immune defence
-
Trinchieri G, Sher A. Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol. 2007;7:179-190.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 179-190
-
-
Trinchieri, G.1
Sher, A.2
-
128
-
-
58149269348
-
Carcinoma-produced factors activatemyeloid cells through TLR2 to stimulatemetastasis
-
KimS, Takahashi H, LinWW,et al.Carcinoma-produced factors activatemyeloid cells through TLR2 to stimulatemetastasis. Nature. 2009;457:102-106.
-
(2009)
Nature
, vol.457
, pp. 102-106
-
-
Kim, S.1
Takahashi, H.2
Lin, W.W.3
-
129
-
-
22544450733
-
Direct stimulation of human T cells via TLR5 and TLR7/8: Flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells
-
Caron G, Duluc D, Fremaux I, et al. Direct stimulation of human T cells via TLR5 and TLR7/8: Flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells. J Immunol. 2005;175:1551-1557.
-
(2005)
J Immunol
, vol.175
, pp. 1551-1557
-
-
Caron, G.1
Duluc, D.2
Fremaux, I.3
-
130
-
-
1542297739
-
TLR2 is expressed on activated T cells as a costimulatory receptor
-
Komai-Koma M, Jones L, Ogg GS, Xu D, Liew FY. TLR2 is expressed on activated T cells as a costimulatory receptor. Proc Natl Acad Sci U S A. 2004;101:3029-3034.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3029-3034
-
-
Komai-Koma, M.1
Jones, L.2
Ogg, G.S.3
Xu, D.4
Liew, F.Y.5
-
131
-
-
31144458579
-
Direct costimulatory effect of TLR3 ligand poly(I:C) on human gamma delta T lymphocytes
-
Wesch D, Beetz S, Oberg HH,Marget M, Krengel K, Kabelitz D. Direct costimulatory effect of TLR3 ligand poly(I:C) on human gamma delta T lymphocytes. J Immunol. 2006;176:1348-1354.
-
(2006)
J Immunol
, vol.176
, pp. 1348-1354
-
-
Wesch, D.1
Beetz, S.2
Oberg, H.H.3
Marget, M.4
Krengel, K.5
Kabelitz, D.6
-
132
-
-
55049118368
-
A combination of Lox-1 and Nox1 regulates TLR9-mediated foam cell formation
-
Lee JG, Lim EJ, Park DW, Lee SH, Kim JR, Baek SH. A combination of Lox-1 and Nox1 regulates TLR9-mediated foam cell formation. Cell Signal. 2008;20:2266-2275.
-
(2008)
Cell Signal
, vol.20
, pp. 2266-2275
-
-
Lee, J.G.1
Lim, E.J.2
Park, D.W.3
Lee, S.H.4
Kim, J.R.5
Baek, S.H.6
-
133
-
-
0347285351
-
Toll-like receptors induce a phagocytic gene program through p38
-
Doyle SE, O'Connell RM, Miranda GA, et al. Toll-like receptors induce a phagocytic gene program through p38. J ExpMed. 2004;199:81-90.
-
(2004)
J ExpMed
, vol.199
, pp. 81-90
-
-
Doyle, S.E.1
O'Connell, R.M.2
Miranda, G.A.3
-
134
-
-
0242361567
-
Crosstalk between LXR and Toll-like receptor signalingmediates bacterial and viral antagonism of cholesterol metabolism
-
Castrillo A, Joseph SB, Vaidya SA, et al. Crosstalk between LXR and Toll-like receptor signalingmediates bacterial and viral antagonism of cholesterol metabolism.Mol Cell. 2003;12:805-816.
-
(2003)
Mol Cell
, vol.12
, pp. 805-816
-
-
Castrillo, A.1
Joseph, S.B.2
Vaidya, S.A.3
-
135
-
-
0037324340
-
Reciprocal regulation of inflammation and lipidmetabolism by liver X receptors
-
Joseph SB, Castrillo A, Laffitte BA,Mangelsdorf DJ, Tontonoz P. Reciprocal regulation of inflammation and lipidmetabolism by liver X receptors. Nat Med. 2003;9:213-219.
-
(2003)
Nat Med
, vol.9
, pp. 213-219
-
-
Joseph, S.B.1
Castrillo, A.2
Laffitte, B.A.3
Mangelsdorf, D.J.4
Tontonoz, P.5
-
136
-
-
9144232256
-
IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA
-
Wagner M, Poeck H, Jahrsdoerfer B, et al. IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA. J Immunol. 2004;172:954-963.
-
(2004)
J Immunol
, vol.172
, pp. 954-963
-
-
Wagner, M.1
Poeck, H.2
Jahrsdoerfer, B.3
-
137
-
-
0242580118
-
Cutting edge: Different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signalregulated kinase-mitogen-activated protein kinase and c-Fos
-
Agrawal S, Agrawal A, Doughty B, et al. Cutting edge: Different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signalregulated kinase-mitogen- activated protein kinase and c-Fos. J Immunol. 2003;171:4984-4989.
-
(2003)
J Immunol
, vol.171
, pp. 4984-4989
-
-
Agrawal, S.1
Agrawal, A.2
Doughty, B.3
-
138
-
-
64149088746
-
Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity
-
Manicassamy S, Ravindran R, Deng J, et al. Toll-like receptor 2-dependent induction of vitamin A-metabolizing enzymes in dendritic cells promotes T regulatory responses and inhibits autoimmunity. Nat Med. 2009;15:401-409.
-
(2009)
Nat Med
, vol.15
, pp. 401-409
-
-
Manicassamy, S.1
Ravindran, R.2
Deng, J.3
-
139
-
-
0041915628
-
Induction of a regulatory T cell type 1 response reduces the development of atherosclerosis in apolipoprotein E-knockoutmice
-
Mallat Z, Gojova A, Brun V, et al. Induction of a regulatory T cell type 1 response reduces the development of atherosclerosis in apolipoprotein E-knockoutmice. Circulation. 2003;108:1232-1237.
-
(2003)
Circulation
, vol.108
, pp. 1232-1237
-
-
Mallat, Z.1
Gojova, A.2
Brun, V.3
-
140
-
-
74649086985
-
Thereceptor SIGIRR suppressesTh17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation
-
GulenMF, Kang Z, Bulek K, et al.Thereceptor SIGIRR suppressesTh17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity. 2010;32:54-66.
-
(2010)
Immunity
, vol.32
, pp. 54-66
-
-
Gulen, M.F.1
Kang, Z.2
Bulek, K.3
-
141
-
-
77949326033
-
Human plasmacytoid dendritic cells supportTh17 cell effector function in response to TLR7 ligation
-
Yu CF, PengWM, Oldenburg J, et al.Human plasmacytoid dendritic cells supportTh17 cell effector function in response to TLR7 ligation. J Immunol. 2010;184:1159-1167.
-
(2010)
J Immunol
, vol.184
, pp. 1159-1167
-
-
Yu, C.F.1
Peng, W.M.2
Oldenburg, J.3
-
142
-
-
66449085101
-
Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans
-
Chou MY, Fogelstrand L, Hartvigsen K, et al. Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans. J Clin Invest. 2009;119:1335-1349.
-
(2009)
J Clin Invest
, vol.119
, pp. 1335-1349
-
-
Chou, M.Y.1
Fogelstrand, L.2
Hartvigsen, K.3
-
143
-
-
77957196909
-
Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression
-
Grimm M, Kim M, Rosenwald A, et al. Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression. Eur J Cancer. 2010;46:2849-2857.
-
(2010)
Eur J Cancer
, vol.46
, pp. 2849-2857
-
-
Grimm, M.1
Kim, M.2
Rosenwald, A.3
-
144
-
-
33646487278
-
Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells
-
Liu H, Komai-Koma M, Xu D, Liew FY. Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells. Proc Natl Acad Sci U S A. 2006;103:7048-7053.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 7048-7053
-
-
Liu, H.1
Komai-Koma, M.2
Xu, D.3
Liew, F.Y.4
-
145
-
-
20044368019
-
Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88
-
Hasan U, Chaffois C, Gaillard C, et al. Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88. J Immunol. 2005;174:2942-2950.
-
(2005)
J Immunol
, vol.174
, pp. 2942-2950
-
-
Hasan, U.1
Chaffois, C.2
Gaillard, C.3
-
146
-
-
70450273130
-
Transcriptional regulation of Tlr11 gene expression in epithelial cells
-
Cai Z, Shi Z, Sanchez A, et al. Transcriptional regulation of Tlr11 gene expression in epithelial cells. J Biol Chem. 2009;284:33088-33096.
-
(2009)
J Biol Chem
, vol.284
, pp. 33088-33096
-
-
Cai, Z.1
Shi, Z.2
Sanchez, A.3
|