Towards the miniaturization of GPCR-based live-cell screening assays

Trends in Biotechnology

Volumn 30, Issue 11, 2012, Pages 566-574

  Martins, Sofia A M ^a,b   Trabuco, João R C ^a   Monteiro, Gabriel A ^a   Chu, Virginia ^b   Conde, João P ^a,b   Prazeres, Miguel F ^a  

^a Instituto de Biotecnologia e Bioengenharia Lisboa   (Portugal)

^b INESC   (Portugal)

Author keywords

Biosensors; Cell microarrays; Drug discovery; G protein coupled receptors; High throughput screening; Microfluidics

Indexed keywords

CELL MICROARRAY; CELL-BASED ASSAYS; DRUG DISCOVERY; G PROTEIN COUPLED RECEPTORS; HIGH-THROUGHPUT; HIGH-THROUGHPUT SCREENING; MICROFLUIDIC TECHNOLOGIES; PHARMACEUTICAL INDUSTRY; RESEARCH EFFORTS; SCREENING ASSAYS;

BIOSENSORS; CELLS; CYTOLOGY; MICROARRAYS; MICROFLUIDICS; MINIATURE INSTRUMENTS; PROTEINS;

DIAGNOSIS;

DRUG; G PROTEIN COUPLED RECEPTOR;

ASSAY; CELL SCREENING; DRUG DETERMINATION; ELECTRONICS; EQUIPMENT DESIGN; FLUID FLOW; FLUID TRANSPORT; LABORATORY DEVICE; LIVE CELL SCREENING ASSAY; MICROARRAY ANALYSIS; MICROFLUIDICS; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SENSOR; SIGNAL TRANSDUCTION;

AUTOMATION; BIOSENSING TECHNIQUES; DRUG EVALUATION, PRECLINICAL; HIGH-THROUGHPUT SCREENING ASSAYS; MICROARRAY ANALYSIS; MICROFLUIDICS; MINIATURIZATION; RECEPTORS, OPIOID;

EID: 84867728152     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2012.07.004     Document Type: Review

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