Evaluation of cannabinoid receptor 2 and metabotropic glutamate receptor 1 functional responses using a cell impedance-based technology

Journal of Biomolecular Screening

Volumn 15, Issue 10, 2010, Pages 1238-1247

  Scandroglio, Paola ^a,b   Brusa, Rossella ^a   Lozza, Gianluca ^a   Mancini, Isabella ^a,c   Petrò, Roberta ^a   Reggiani, Angelo ^a,d   Beltramo, Massimiliano ^a,e  

^a Schering Plough Research Institute   (Italy)

^b Roche Diagnostics   (Italy)

^c OPIS Srl   (Italy)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^e UMR85 PHYSIOLOGIE DE LA REPRODUCTION ET DES COMPORTEMENTS   (France)

Author keywords

assay; CB2; impedance; label free technology; mGluR1

Indexed keywords

(3,4 DIHYDRO 2H PYRANO[2,3 B]QUINOLIN 7 YL) (4 METHOXYCYCLOHEXYL)METHANONE; 1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 1 DEOXY 3 (1,1 DIMETHYLBUTYL) DELTA8 TETRAHYDROCANNABINOL; 3,5 DIHYDROPHENYLGLYCINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; 6 AMINO N CYCLOHEXYL N,3 DIMETHYLTHIAZOLO[3,2 A]BENZIMIDAZOLE 2 CARBOXAMIDE; 6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; 7 (HYDROXYIMINO)CYCLOPROPA[B]CHROMEN 1A CARBOXYLATE ETHYL ESTER; BAY 367620; CALCIUM ION; CANNABINOID 2 RECEPTOR; CYCLIC AMP; GLUTAMIC ACID; HEXAHYDRO 5 METHYLENE 6A (2 NAPHTHALENYLMETHYL) 1H CYCLOPENTA[C]FURAN 1 ONE; JNJ 16259685; METABOTROPIC RECEPTOR 1; QUISQUALIC ACID; SCH 1014222; UNCLASSIFIED DRUG; YM 298198;

ANIMAL CELL; ARTICLE; BIOSENSOR; CELL IMPEDANCE; CELL LINE; CHO CELL; DRUG DOSE REDUCTION; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; EVALUATION; IMPEDANCE; INTERMETHOD COMPARISON; NONHUMAN; PRIORITY JOURNAL;

ANALGESICS; ANIMALS; BENZIMIDAZOLES; BIOLOGICAL ASSAY; CALCIUM; CANNABINOIDS; CHO CELLS; CHROMONES; CRICETINAE; CRICETULUS; CYCLIC AMP; CYCLOHEXANOLS; CYCLOLEUCINE; ELECTRIC IMPEDANCE; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; GLYCINE; INDOLES; NAPHTHALENES; NEUROPROTECTIVE AGENTS; QUINOLINES; QUISQUALIC ACID; RECEPTOR, CANNABINOID, CB2; RECEPTORS, METABOTROPIC GLUTAMATE; RESORCINOLS; SIGNAL TRANSDUCTION; THIAZOLES;

EID: 78049250124     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057110375615     Document Type: Article

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