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Volumn 2, Issue 2, 2005, Pages 163-170

G-protein-coupled receptor screening technologies

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LIGAND; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

EID: 21744454662     PISSN: 17406749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddtec.2005.05.009     Document Type: Review
Times cited : (10)

References (25)
  • 1
    • 12844283957 scopus 로고    scopus 로고
    • High-throughput drug discovery: What can we expect from HTS?
    • P. Gribbon et al. High-throughput drug discovery: What can we expect from HTS? Drug Discov. Today 10 2005 17-22
    • (2005) Drug Discov. Today , vol.10 , pp. 17-22
    • Gribbon, P.1
  • 2
    • 0031758635 scopus 로고    scopus 로고
    • The application of high-throughput screening to novel lead discovery
    • B.A. Kenny et al. The application of high-throughput screening to novel lead discovery Prog. Drug Res. 51 1998 245-269
    • (1998) Prog. Drug Res. , vol.51 , pp. 245-269
    • Kenny, B.A.1
  • 3
    • 0036189809 scopus 로고    scopus 로고
    • G protein-coupled receptor signalling and cross-talk: Achieving rapidity and specificity
    • E.M. Hur and K.T. Kim G protein-coupled receptor signalling and cross-talk: Achieving rapidity and specificity Cell. Signal. 14 2002 397-405
    • (2002) Cell. Signal , vol.14 , pp. 397-405
    • Hur, E.M.1    Kim, K.T.2
  • 4
    • 3242878402 scopus 로고    scopus 로고
    • PRED-GPCR: GPCR recognition and family classification server
    • P.K. Papasaikas et al. PRED-GPCR: GPCR recognition and family classification server Nucleic Acids Res. 32 2004 W380-W382
    • (2004) Nucleic Acids Res. , vol.32
    • Papasaikas, P.K.1
  • 5
    • 0038024615 scopus 로고    scopus 로고
    • The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints
    • (see comment). Comment in: Mol. Pharmacol. 2003;63:1202-1205; PMID: 1276-1327
    • Fredriksson, R. et al. (2003) The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints (see comment). Comment in: Mol. Pharmacol. 2003;63:1202-1205; PMID: 1276-1327. Mol. Pharmacol. 63, 1256-1272
    • (2003) Mol. Pharmacol. , vol.63 , pp. 1256-1272
    • Fredriksson, R.1
  • 6
    • 0242352554 scopus 로고    scopus 로고
    • RAMPs: 5 years on, where to now?
    • M. Morfis et al. RAMPs: 5 years on, where to now? Trends Pharmacol. Sci. 24 2003 596-601
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 596-601
    • Morfis, M.1
  • 7
    • 0036258990 scopus 로고    scopus 로고
    • G protein-coupled receptor allosterism and complexing
    • A. Christopoulos and T. Kenakin G protein-coupled receptor allosterism and complexing Pharmacol. Rev. 54 2002 323-374
    • (2002) Pharmacol. Rev. , vol.54 , pp. 323-374
    • Christopoulos, A.1    Kenakin, T.2
  • 8
    • 0024969084 scopus 로고
    • Scintillation proximity assay
    • N. Bosworth and P. Towers Scintillation proximity assay Nature 341 1989 167-168
    • (1989) Nature , vol.341 , pp. 167-168
    • Bosworth, N.1    Towers, P.2
  • 9
    • 0036978077 scopus 로고    scopus 로고
    • Use of fluorescence polarization detection for the measurement of fluopeptidetm binding to G protein-coupled receptors
    • A. Gagne et al. Use of fluorescence polarization detection for the measurement of fluopeptidetm binding to G protein-coupled receptors J. Recept. Signal Transduct. Res. 22 2002 333-343
    • (2002) J. Recept. Signal Transduct. Res. , vol.22 , pp. 333-343
    • Gagne, A.1
  • 10
    • 0033168002 scopus 로고    scopus 로고
    • A homogeneous and multiplexed immunoassay for high-throughput screening using fluorometric microvolume assay technology
    • E.E. Swartzman et al. A homogeneous and multiplexed immunoassay for high-throughput screening using fluorometric microvolume assay technology Anal. Biochem. 271 1999 143-151
    • (1999) Anal. Biochem. , vol.271 , pp. 143-151
    • Swartzman, E.E.1
  • 11
    • 0037305047 scopus 로고    scopus 로고
    • Principles: Extending the utility of [35S]GTP gamma S binding assays
    • G. Milligan Principles: Extending the utility of [35S]GTP gamma S binding assays Trends Pharmacol. Sci. 24 2003 87-90
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 87-90
    • Milligan, G.1
  • 12
    • 4344614482 scopus 로고    scopus 로고
    • Nonradioactive GTP binding assay to monitor activation of G protein-coupled receptors
    • H. Frang et al. Nonradioactive GTP binding assay to monitor activation of G protein-coupled receptors Assay Drug Dev. Technol. 1 2003 275-280
    • (2003) Assay Drug Dev. Technol. , vol.1 , pp. 275-280
    • Frang, H.1
  • 13
    • 3242779121 scopus 로고    scopus 로고
    • i-linked G protein-coupled receptors
    • i -linked G protein-coupled receptors Assay Drug Dev. Technol. 1 2003 261-273
    • (2003) Assay Drug Dev. Technol. , vol.1 , pp. 261-273
    • Ferrer, M.1
  • 14
    • 0033932181 scopus 로고    scopus 로고
    • Cell-based, high-content screen for receptor internalization, recycling and intracellular trafficking
    • R.N. Ghosh et al. Cell-based, high-content screen for receptor internalization, recycling and intracellular trafficking Biotechniques 29 2000 170-175
    • (2000) Biotechniques , vol.29 , pp. 170-175
    • Ghosh, R.N.1
  • 15
    • 0012132962 scopus 로고    scopus 로고
    • The cellular distribution of fluorescently labeled arrestins provides a robust, sensitive, and universal assay for screening G protein-coupled receptors
    • R.H. Oakley et al. The cellular distribution of fluorescently labeled arrestins provides a robust, sensitive, and universal assay for screening G protein-coupled receptors Assay Drug Dev. Technol. 1 2002 21-30
    • (2002) Assay Drug Dev. Technol. , vol.1 , pp. 21-30
    • Oakley, R.H.1
  • 16
    • 0031025764 scopus 로고    scopus 로고
    • Internal trafficking and surface mobility of a functionally intact beta2-adrenergic receptor-green fluorescent protein conjugate
    • L.S. Barak et al. Internal trafficking and surface mobility of a functionally intact beta2-adrenergic receptor-green fluorescent protein conjugate Mol. Pharmacol. 51 1997 177-184
    • (1997) Mol. Pharmacol. , vol.51 , pp. 177-184
    • Barak, L.S.1
  • 17
    • 0030736417 scopus 로고    scopus 로고
    • A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation
    • L.S. Barak et al. A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation J. Biol. Chem. 272 1997 27497-27500
    • (1997) J. Biol. Chem. , vol.272 , pp. 27497-27500
    • Barak, L.S.1
  • 18
    • 0032603524 scopus 로고    scopus 로고
    • 2+] using the fluorometric imaging plate reader (FLIPR)
    • 2+] using the fluorometric imaging plate reader (FLIPR) Methods Mol. Biol. 114 1999 125-133
    • (1999) Methods Mol. Biol. , vol.114 , pp. 125-133
    • Sullivan, E.1
  • 19
    • 0036451532 scopus 로고    scopus 로고
    • Aequorin-based functional assays for G-protein-coupled receptors, ion channels, and tyrosine kinase receptors
    • V.J. Dupriez et al. Aequorin-based functional assays for G-protein-coupled receptors, ion channels, and tyrosine kinase receptors Receptors Channels 8 2002 319-330
    • (2002) Receptors Channels , vol.8 , pp. 319-330
    • Dupriez, V.J.1
  • 20
    • 13844286793 scopus 로고    scopus 로고
    • Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader
    • P. Hodder et al. Miniaturization of intracellular calcium functional assays to 1536-well plate format using a fluorometric imaging plate reader J. Biomol. Screen. 9 2004 417-426
    • (2004) J. Biomol. Screen. , vol.9 , pp. 417-426
    • Hodder, P.1
  • 21
    • 1242308248 scopus 로고    scopus 로고
    • cAMP detection methods in HTS: Selecting the best from the rest
    • C. Williams cAMP detection methods in HTS: Selecting the best from the rest Nat. Rev. Drug Discov. 3 2004 125-135
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 125-135
    • Williams, C.1
  • 22
    • 0033151694 scopus 로고    scopus 로고
    • i-coupled receptors
    • i-coupled receptors Anal. Biochem. 270 1999 242-248
    • (1999) Anal. Biochem. , vol.270 , pp. 242-248
    • Coward, P.1
  • 23
    • 0042890599 scopus 로고    scopus 로고
    • Galpha(16/z) chimeras efficiently link a wide range of G protein-coupled receptors to calcium mobilization
    • A.M. Liu et al. Galpha(16/z) chimeras efficiently link a wide range of G protein-coupled receptors to calcium mobilization J. Biomol. Screen. 8 2003 39-49
    • (2003) J. Biomol. Screen. , vol.8 , pp. 39-49
    • Liu, A.M.1
  • 24
    • 0037333313 scopus 로고    scopus 로고
    • Development of an intact cell reporter gene beta-lactamase assay for G protein-coupled receptors for high-throughput screening
    • P. Kunapuli et al. Development of an intact cell reporter gene beta-lactamase assay for G protein-coupled receptors for high-throughput screening Anal. Biochem. 314 2003 16-29
    • (2003) Anal. Biochem. , vol.314 , pp. 16-29
    • Kunapuli, P.1
  • 25
    • 0035398487 scopus 로고    scopus 로고
    • G-protein-coupled receptors and signaling networks: Emerging paradigms
    • M.J. Marinissen and J.S. Gutkind G-protein-coupled receptors and signaling networks: Emerging paradigms Trends Pharmacol. Sci. 22 2001 368-376
    • (2001) Trends Pharmacol. Sci. , vol.22 , pp. 368-376
    • Marinissen, M.J.1    Gutkind, J.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.