The heritability of human longevity: A population-based study of 2872 Danish twin pairs born 1870-1900

Human Genetics

Volumn 97, Issue 3, 1996, Pages 319-323

  Herskind, Anne Maria ^a   McGue, Matthew ^b   Holm, Niels V ^a   Sørensen, Thorkild I A ^c   Harvald, Bent ^a   Vaupel, James W ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b UNIVERSITY OF MINNESOTA   (United States)

^c DEPARTMENT OF EPIDEMIOLOGY RESEARCH   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; COHORT ANALYSIS; DENMARK; ENVIRONMENTAL FACTOR; FEMALE; HERITABILITY; HUMAN; LONGEVITY; MALE; MODEL; NORMAL HUMAN; POPULATION GENETICS; PRIORITY JOURNAL; SEX DIFFERENCE; TWINS; ZYGOSITY;

EID: 0030062815     PISSN: 03406717     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02185763     Document Type: Article

References (26)

1. Berg K (1994) Lp(a) lipoprotein: an overview. Chem Phys Lipids 67/68:9-16
2. Christensen K, Vaupel JW, Holm NV, Yashin AI (1995) Mortality among twins after age 6: fetal origins hypothesis versus twin method. BMJ 310:432-436
3. Cohen BH (1964) Family pattern of mortality and life-span. Q Rev Biol 39:130-181
4. Fisher RA (1930) The genetical theory of natural selection. Clarendon, Oxford
5. Hauge M, Harvald B, Fischer M, Gotlieb-Jensen N, Juel-Nielsen N, Raebild I, et al (1968) The Danish Twin Register. Acta Genet Med Gemellol (Roma) 2:315-331
6. Hauge M (1981) The Danish twin register. In: Mednick SA, Baert AE, Bachmann BP (eds) Prospective longitudinal research. Oxford Medical, Oxford, pp 217-222
7. Heath AC, Neale MC, Hewitt JK, Eaves LJ, Fulker DW (1989) Testing structural equation models for twin data using LIS-REL. Behav Genet 19:9-35
8. Holm NV (1983) The use of twin studies to investigate causes of diseases with complex etiology with a focus on cancer (in Danish). Thesis, Odense University, Odense
9. Hrubec Z, Neel JV (1981) Familial factors in early deaths: twins followed 30 years to ages 51-61 in 1978. Hum Genet 59:39-46
10. Jarvik L, Fałek A, Kallmann FJ, Lorge I (1960) Survival trends in a senescent twin population. Am J Hum Genet 12:170-179
11. Kervinen K, Savolainen MJ, Salokannel J. Hynninen A, Heikkinen J. Ehnholm C, et al (1994) Apolipoprotein E and B polymorphisms - longevity factors assessed in nonagenarians. Atherosclerosis 105:89-95
12. Lykken DT (1978) The diagnosis of zygosity in twins. Behav Genet 8:437-473
13. Lykken DT (1982) Research with twins: the concept of emergenesis. Psychophysiology 19:361-373
14. Lykken DT, McGue M, Tellegen A, Bouchard TJ (1993) Emergenesis. Genetic traits that may not run in families. Am Psychol 47:1565-1577
15. Mayer PJ (1991) Inheritance of longevity evinces no secular trend among members of six New England families born 1650-1874. Am J Hum Biol 3:49-58
16. McGue M, Vaupel JW, Holm N, Harvald B (1993) Longevity is moderately heritable in a sample of Danish twins born 1870-1880. J Gerontol 48:B237-B244
17. Neale MC, Cardon LR (1992) Methodology for genetic studies of twins and families. 1st edn. Kluwer, Dordrecht
18. Neale MC (1994) Mx: statistical modeling. 2nd edn. Department of Psychiatry, Box 710 MCV, Richmond, VA 23298, USA
19. Pearl R (1931) Studies on human longevity. IV. The inheritance of longevity. Hum Biol 3:245-269
20. Roff DA, Mousseau TA (1987) Quantitative genetics and fitness: lessons from Drosophila. Heredity 58:103-118
21. Schächter F, Cohen D, Kirkwood T (1993) Prospects for the genetics of human longevity. Hum Genet 91:519-526
22. Schächter F, Faure-Delanef L, Guénot F, Rouger H, Froguel P, Lesueur-Ginot L, et al (1994) Genetic associations with human longevity at the APOE and ACE loci. Nature Genet 6:29-32
23. Sorensen TIA, Nielsen GG, Andersen PK, Teasdale TW (1988) Genetic and environmental influences on premature death in adult adoptees. N Engl J Med 318:727-732
24. Vaupel JW (1988) Inherited frailty and longevity. Demography 25:277-287
25. Wyshak G (1978) Fertility and longevity in twins, sibs, and parents of twins. Soc Biol 25:315-330
26. Yashin AI, Iachine IA (1995) Genetic analysis of durations: Correlated frailty model applied to survival of Danish twins. Genet Epidemiol 12:529-538