The endocannabinoid, anandamide, augments notch-1 signaling in cultured cortical neurons exposed to amyloid- β and in the cortex of aged rats

Journal of Biological Chemistry

Volumn 287, Issue 41, 2012, Pages 34709-34721

  Tanveer, Riffat ^a   Gowran, Aoife ^a   Noonan, Janis ^a   Keating, Sinead E ^a   Bowie, Andrew G ^a   Campbell, Veronica A ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEINS; CHRONIC TREATMENT; COGNITIVE IMPAIRMENT; CULTURED CORTICAL NEURONS; CULTURED NEURONS; DISEASE PROCESS; ENDOCANNABINOID; ENDOGENOUS INHIBITOR; IN-VITRO; LEARNING AND MEMORY; NATURAL PROCESS; NEURODEGENERATION; NEUROGENESIS; NOTCH SIGNALING; SECRETASES; STIMULATORY EFFECTS;

GLYCOPROTEINS;

SIGNALING;

2 ARACHIDONOYLGLYCEROL; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; ANANDAMIDE; CYCLOHEXYLCARBAMIC ACID 3' CARBAMOYLBIPHENYL 3 YL ESTER; GAMMA SECRETASE; NICASTRIN; NOTCH1 RECEPTOR;

AGED; AGING; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; BRAIN CORTEX; CONTROLLED STUDY; DRUG MECHANISM; HIPPOCAMPUS; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ARACHIDONIC ACIDS; BENZAMIDES; CARBAMATES; CELLS, CULTURED; CEREBRAL CORTEX; ENDOCANNABINOIDS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLYCERIDES; HIPPOCAMPUS; MALE; MEMBRANE GLYCOPROTEINS; NEURONS; PEPTIDE FRAGMENTS; POLYUNSATURATED ALKAMIDES; RATS; RATS, WISTAR; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84867257671     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.350678     Document Type: Article

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