-
1
-
-
0031969718
-
Molecular pathogenesis of sporadic and familial forms of Alzheimer's disease
-
Ray, W.J. et al. (1998) Molecular pathogenesis of sporadic and familial forms of Alzheimer's disease. Mol. Med. Today 4, 151-157
-
(1998)
Mol. Med. Today
, vol.4
, pp. 151-157
-
-
Ray, W.J.1
-
3
-
-
0031741247
-
New phosphorylation sites.identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry
-
Hanger, D.P. et al. (1998) New phosphorylation sites.identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry. J. Neurochem. 71, 2465-2476
-
(1998)
J. Neurochem.
, vol.71
, pp. 2465-2476
-
-
Hanger, D.P.1
-
4
-
-
0028675873
-
Alzheimer's disease-like phosphorylation of the microtubule- associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells
-
Lovestone, S. et al. (1994) Alzheimer's disease-like phosphorylation of the microtubule- associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Curr. Biol. 4, 1077-1086
-
(1994)
Curr. Biol.
, vol.4
, pp. 1077-1086
-
-
Lovestone, S.1
-
5
-
-
0030937952
-
The phosphorylation of tau: A critical stage in neurodevelopment and neurodegenerative processes
-
Lovestone, S. and Reynolds, C.H. (1997) The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative processes. Neuroscience 78, 309-324
-
(1997)
Neuroscience
, vol.78
, pp. 309-324
-
-
Lovestone, S.1
Reynolds, C.H.2
-
6
-
-
0033561207
-
Lithium reduces tau phosphorylation: Effects in living cells and in neurons at therapeutic concentrations
-
Lovestone, S. et al. (1999) Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations. Biol. Psychiatry 45, 995-1003
-
(1999)
Biol. Psychiatry
, vol.45
, pp. 995-1003
-
-
Lovestone, S.1
-
7
-
-
0033611663
-
The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction
-
Cohen, P. (1999) The Croonian Lecture 1998. Identification of a protein kinase cascade of major importance in insulin signal transduction. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 354, 485-495
-
(1999)
Philos. Trans. R. Soc. Lond. B. Biol. Sci.
, vol.354
, pp. 485-495
-
-
Cohen, P.1
-
8
-
-
0030748390
-
Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons
-
Hong, M. and Lee, V.M.Y. (1997) Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons. J. Biol. Chem. 272, 19547-19553
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19547-19553
-
-
Hong, M.1
Lee, V.M.Y.2
-
9
-
-
0032518695
-
Signal transduction by the Wnt family of ligands
-
Dale, T.C. (1998) Signal transduction by the Wnt family of ligands. Biochem. J. 329, 209-223
-
(1998)
Biochem. J.
, vol.329
, pp. 209-223
-
-
Dale, T.C.1
-
10
-
-
0029811434
-
Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C
-
Cook, D. et al. (1996) Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C. EMBO J. 15, 4526-4536
-
(1996)
EMBO J.
, vol.15
, pp. 4526-4536
-
-
Cook, D.1
-
11
-
-
0033605420
-
Protein kinase Czeta is a negative regulator of protein kinase B activity
-
Doombos, P.P. et al. (1999) Protein kinase Czeta is a negative regulator of protein kinase B activity. J. Biol. Chem. 274, 8589-8596
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8589-8596
-
-
Doombos, P.P.1
-
12
-
-
0032562603
-
Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β
-
Behrens, J. et al. (1998) Functional interaction of an axin homolog, conductin, with β-catenin, APC, and GSK3β. Science 280, 596-599
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
-
13
-
-
0032492954
-
Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β
-
Hart, M.J. et al. (1998) Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β. Curr. Biol. 8, 573-581
-
(1998)
Curr. Biol.
, vol.8
, pp. 573-581
-
-
Hart, M.J.1
-
14
-
-
0033577732
-
Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription
-
Smalley, M.J. et al. (1999) Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription. EMBO J. 18, 2823-2835
-
(1999)
EMBO J.
, vol.18
, pp. 2823-2835
-
-
Smalley, M.J.1
-
15
-
-
0033617522
-
Notch signaling: Cell fate control and signal integration in development
-
Artavanis-Tsakonas, S. et al. (1999) Notch signaling: cell fate control and signal integration in development. Science 284, 770-776
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
-
16
-
-
0033535504
-
Presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain
-
De Strooper, B. et al. (1999) Presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain. Nature 398, 518-522
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
-
17
-
-
0030779784
-
Skeletal and CNS defects in Presenilin-1-deficient mice
-
Shen, J. et al. (1997) Skeletal and CNS defects in Presenilin-1-deficient mice. Cell 89, 629-639
-
(1997)
Cell
, vol.89
, pp. 629-639
-
-
Shen, J.1
-
18
-
-
0033536072
-
Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations
-
Song, W.H. et al. (1999) Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations. Proc. Natl. Acad. Sci. U. S. A. 96, 6959-6963
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 6959-6963
-
-
Song, W.H.1
-
19
-
-
0033214070
-
A loss of function mutation of presenilin-2 interferes with amyloid β-peptide production and Notch signalling
-
Steiner, H. et al. (1999) A loss of function mutation of presenilin-2 interferes with amyloid β-peptide production and Notch signalling. J. Biol. Chem. 40, 28669-28673
-
(1999)
J. Biol. Chem.
, vol.40
, pp. 28669-28673
-
-
Steiner, H.1
-
20
-
-
17744401440
-
Presenilin 1 is required for Notch1 Dll1 expression in the paraxial mesoderm
-
Wong, P.C. et al. (1997) Presenilin 1 is required for Notch1 Dll1 expression in the paraxial mesoderm. Nature. 387, 288-292
-
(1997)
Nature
, vol.387
, pp. 288-292
-
-
Wong, P.C.1
-
21
-
-
0029670476
-
Interaction between wingless and notch signaling pathways mediated by dishevelled
-
Axelrod, J.D. et al. (1996) Interaction between wingless and notch signaling pathways mediated by dishevelled. Science. 271, 1826-1832
-
(1996)
Science
, vol.271
, pp. 1826-1832
-
-
Axelrod, J.D.1
-
22
-
-
0032972547
-
Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and β-catenin
-
Levesque, G. et al. (1999) Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and β-catenin. J. Neurochem. 72, 999-1008
-
(1999)
J. Neurochem.
, vol.72
, pp. 999-1008
-
-
Levesque, G.1
-
23
-
-
0033515530
-
Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071
-
Stahl, B. et al. (1999) Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071. J. Biol. Chem. 274, 9141-9148
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9141-9148
-
-
Stahl, B.1
-
24
-
-
0033601985
-
Isolation of human delta-catenin and its binding specificity with presenilin 1
-
Tanahashi, H. and Tabira, T. (1999) Isolation of human delta-catenin and its binding specificity with presenilin 1. Neuroreport 10, 563-568
-
(1999)
Neuroreport
, vol.10
, pp. 563-568
-
-
Tanahashi, H.1
Tabira, T.2
-
25
-
-
0030904751
-
Presenilin 1 interaction in the brain with a novel member of the Armadillo family
-
Zhou, J.H. et al. (1997) Presenilin 1 interaction in the brain with a novel member of the Armadillo family, Neuroreport 8, 2085-2090
-
(1997)
Neuroreport
, vol.8
, pp. 2085-2090
-
-
Zhou, J.H.1
-
26
-
-
0033151570
-
Presenilin 1 facilitates the constitutive turnover of β-catenin: Differential activity of Alzheimer's disease-linked PS1 mutants in the β-catenin-signaling pathway
-
Kang, D.E. et al. Presenilin 1 facilitates the constitutive turnover of β-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the β-catenin-signaling pathway. J. Neurosci. 19, 4229-4237
-
J. Neurosci.
, vol.19
, pp. 4229-4237
-
-
Kang, D.E.1
-
27
-
-
0032531793
-
Destabilization of β-catenin by mutations in presenilin-1 potentiates neuronal apoptosis
-
Zhang, Z.H. et al. (1998) Destabilization of β-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature 395, 698-702
-
(1998)
Nature
, vol.395
, pp. 698-702
-
-
Zhang, Z.H.1
-
28
-
-
0031866596
-
Direct association of presenilin-1 with β-catenin
-
Murayama, M. et al. (1998) Direct association of presenilin-1 with β-catenin. FEBS Lett. 433, 73-77
-
(1998)
FEBS Lett.
, vol.433
, pp. 73-77
-
-
Murayama, M.1
-
29
-
-
0033168352
-
Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB
-
Weihl, C.C. et al. (1999) Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB. J. Neurosci. 19, 5360-5369
-
(1999)
J. Neurosci.
, vol.19
, pp. 5360-5369
-
-
Weihl, C.C.1
-
30
-
-
0032568821
-
The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains β-catenin
-
Yu, G. et al. (1998) The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains β-catenin, J. Biol. Chem. 273, 16470-16475
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16470-16475
-
-
Yu, G.1
-
31
-
-
0033014046
-
Evidence for a physical interaction between presenilin and Notch
-
Ray, W.J. et al. (1999) Evidence for a physical interaction between presenilin and Notch, Proc. Natl. Acad. Sci. U. S. A. 96, 3263-3268
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 3263-3268
-
-
Ray, W.J.1
-
32
-
-
0032905727
-
Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of β-catenin, a component of the presenilin protein complex
-
Nishimura, M. et al. (1999) Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of β-catenin, a component of the presenilin protein complex. Nat. Med. 5, 164-169
-
(1999)
Nat. Med.
, vol.5
, pp. 164-169
-
-
Nishimura, M.1
-
33
-
-
0032400818
-
Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis
-
Bursztajn, S. et al. (1998) Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis. J. Neurosci. 18, 9790-9799
-
(1998)
J. Neurosci.
, vol.18
, pp. 9790-9799
-
-
Bursztajn, S.1
-
34
-
-
0031039650
-
Tau phosphorylation in cells transfected with wild-type or an Alzheimer's disease mutant presenilin 1
-
Irving, N.G. and Miller, C.C.J. (1997) Tau phosphorylation in cells transfected with wild-type or an Alzheimer's disease mutant presenilin 1. Neurosci. Lett. 222, 71-74
-
(1997)
Neurosci. Lett.
, vol.222
, pp. 71-74
-
-
Irving, N.G.1
Miller, C.C.J.2
-
35
-
-
13144265717
-
Presenilin 1 associates with glycogen synthase kinase-3β and its substrate tau
-
Takashima, A. et al. (1998) Presenilin 1 associates with glycogen synthase kinase-3β and its substrate tau. Proc. Natl. Acad. Sci. U. S. A. 95, 9637-9641
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 9637-9641
-
-
Takashima, A.1
|