Aβ-mediated activation of the apoptotic cascade in cultured cortical neurones: A role for cathepsin-L

Neurobiology of Aging

Volumn 25, Issue 1, 2004, Pages 83-91

  Boland, Barry ^a   Campbell, Veronica ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Apoptosis; Cathepsin L; Cortical neurones; Amyloid

Indexed keywords

AMYLOID BETA PROTEIN; BENZYLOXYCARBONYLPHENYLALANYLPHENYLALANYL FLUOROMETHYL KETONE; CASPASE 3; CATHEPSIN D; CATHEPSIN L; DNA FRAGMENT; ENZYME INHIBITOR; OCTAPEPTIDE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN[1-40]; CASP3 PROTEIN, RAT; CASPASE; CATHEPSIN; CYSTEINE PROTEINASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEPTIDE FRAGMENT;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CELL CULTURE; CELL PROTECTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; DNA CLEAVAGE; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANALYSIS OF VARIANCE; ANIMAL; BRAIN CORTEX; COMPARATIVE STUDY; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG INTERACTION; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; NERVE CELL; NEWBORN; NICK END LABELING; WESTERN BLOTTING; WISTAR RAT;

AMYLOID BETA-PROTEIN; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASES; CATHEPSINS; CELLS, CULTURED; CEREBRAL CORTEX; CYSTEINE ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; NEURONS; PEPTIDE FRAGMENTS; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, WISTAR;

EID: 0346850963     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(03)00034-4     Document Type: Article

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