메뉴 건너뛰기




Volumn 23, Issue 5, 2012, Pages 785-790

Analyzing and engineering cell signaling modules with synthetic biology

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL REACTIONS; CELLULAR RESPONSE; ENDOGENOUS SIGNALING; ENGINEERING CELLS; ENVIRONMENTAL CUES; EX-VIVO; FUNDAMENTAL DESIGN; PROTEIN INTERACTION; SIGNAL TRANSMISSION; SIGNALING PATHWAYS; SYNTHETIC BIOLOGY;

EID: 84867203218     PISSN: 09581669     EISSN: 18790429     Source Type: Journal    
DOI: 10.1016/j.copbio.2012.01.004     Document Type: Review
Times cited : (10)

References (52)
  • 2
    • 0037079054 scopus 로고    scopus 로고
    • Computational systems biology
    • Kitano H. Computational systems biology. Nature 2002, 420:206-210.
    • (2002) Nature , vol.420 , pp. 206-210
    • Kitano, H.1
  • 4
    • 62149128986 scopus 로고    scopus 로고
    • The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation
    • Good M., Tang G., Singleton J., Reményi A., Lim W.A. The Ste5 scaffold directs mating signaling by catalytically unlocking the Fus3 MAP kinase for activation. Cell 2009, 136:1085-1097.
    • (2009) Cell , vol.136 , pp. 1085-1097
    • Good, M.1    Tang, G.2    Singleton, J.3    Reményi, A.4    Lim, W.A.5
  • 5
    • 77951708374 scopus 로고    scopus 로고
    • Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity
    • Zeng W., Sun L., Jiang X., Chen X., Hou F., Adhikari A., Xu M., Chen Z.J. Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity. Cell 2010, 141:315-330.
    • (2010) Cell , vol.141 , pp. 315-330
    • Zeng, W.1    Sun, L.2    Jiang, X.3    Chen, X.4    Hou, F.5    Adhikari, A.6    Xu, M.7    Chen, Z.J.8
  • 6
    • 79251534050 scopus 로고    scopus 로고
    • Ultrasensitivity in the regulation of Cdc25C by Cdk1
    • Trunnell N.B., Poon A.C., Kim S.Y., Ferrell J.E. Ultrasensitivity in the regulation of Cdc25C by Cdk1. Mol Cell 2011, 41:263-274.
    • (2011) Mol Cell , vol.41 , pp. 263-274
    • Trunnell, N.B.1    Poon, A.C.2    Kim, S.Y.3    Ferrell, J.E.4
  • 7
    • 0023667788 scopus 로고
    • Nuclear reconstitution in vitro: stages of assembly around protein-free DNA
    • Newport J. Nuclear reconstitution in vitro: stages of assembly around protein-free DNA. Cell 1987, 48:205-217.
    • (1987) Cell , vol.48 , pp. 205-217
    • Newport, J.1
  • 9
    • 80053292274 scopus 로고    scopus 로고
    • Self-reproduction of supramolecular giant vesicles combined with the amplification of encapsulated DNA
    • Kurihara K., Tamura M., Shohda K., Toyota T., Suzuki K., Sugawara T. Self-reproduction of supramolecular giant vesicles combined with the amplification of encapsulated DNA. Nat Chem 2011, 3:775-781.
    • (2011) Nat Chem , vol.3 , pp. 775-781
    • Kurihara, K.1    Tamura, M.2    Shohda, K.3    Toyota, T.4    Suzuki, K.5    Sugawara, T.6
  • 13
    • 78650842310 scopus 로고    scopus 로고
    • Driving the cell cycle with a minimal CDK control network
    • Coudreuse D., Nurse P. Driving the cell cycle with a minimal CDK control network. Nature 2010, 468:1074-1079.
    • (2010) Nature , vol.468 , pp. 1074-1079
    • Coudreuse, D.1    Nurse, P.2
  • 14
    • 78650929625 scopus 로고    scopus 로고
    • Tunable signal processing in synthetic MAP kinase cascades
    • O'Shaughnessy E.C., Palani S., Collins J.J., Sarkar C.A. Tunable signal processing in synthetic MAP kinase cascades. Cell 2011, 144:119-131.
    • (2011) Cell , vol.144 , pp. 119-131
    • O'Shaughnessy, E.C.1    Palani, S.2    Collins, J.J.3    Sarkar, C.A.4
  • 15
    • 45149099936 scopus 로고    scopus 로고
    • Reconstitution of Mdm2-dependent post-translational modifications of p53 in yeast
    • Di Ventura B., Funaya C., Antony C., Knop M., Serrano L. Reconstitution of Mdm2-dependent post-translational modifications of p53 in yeast. PLoS ONE 2008, 3:e1507.
    • (2008) PLoS ONE , vol.3
    • Di Ventura, B.1    Funaya, C.2    Antony, C.3    Knop, M.4    Serrano, L.5
  • 17
    • 70350452750 scopus 로고    scopus 로고
    • Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling
    • Kiel C., Serrano L. Cell type-specific importance of ras-c-raf complex association rate constants for MAPK signaling. Sci Signal 2009, 2:ra38.
    • (2009) Sci Signal , vol.2
    • Kiel, C.1    Serrano, L.2
  • 19
    • 77955645503 scopus 로고    scopus 로고
    • A genetic circuit system based on quorum sensing signaling for directed evolution of quorum-quenching enzymes
    • Kim J.H., Lee S.C., Kyeong H.H., Kim H.S. A genetic circuit system based on quorum sensing signaling for directed evolution of quorum-quenching enzymes. ChemBioChem 2010, 11:1748-1753.
    • (2010) ChemBioChem , vol.11 , pp. 1748-1753
    • Kim, J.H.1    Lee, S.C.2    Kyeong, H.H.3    Kim, H.S.4
  • 20
    • 23444450226 scopus 로고    scopus 로고
    • Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design
    • Chica R.A., Doucet N., Pelletier J.N. Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design. Curr Opin Biotechnol 2005, 16:378-384.
    • (2005) Curr Opin Biotechnol , vol.16 , pp. 378-384
    • Chica, R.A.1    Doucet, N.2    Pelletier, J.N.3
  • 21
    • 34249885757 scopus 로고    scopus 로고
    • Engineering synthetic signaling proteins with ultrasensitive input/output control
    • Dueber J.E., Mirsky E.A., Lim W.A. Engineering synthetic signaling proteins with ultrasensitive input/output control. Nat Biotechnol 2007, 25:660-662.
    • (2007) Nat Biotechnol , vol.25 , pp. 660-662
    • Dueber, J.E.1    Mirsky, E.A.2    Lim, W.A.3
  • 22
    • 72949090352 scopus 로고    scopus 로고
    • Incorporation of unnatural amino acids for synthetic biology
    • Voloshchuk N., Montclare J.K. Incorporation of unnatural amino acids for synthetic biology. Mol Biosyst 2010, 6:65-80.
    • (2010) Mol Biosyst , vol.6 , pp. 65-80
    • Voloshchuk, N.1    Montclare, J.K.2
  • 23
  • 25
    • 51349089700 scopus 로고    scopus 로고
    • Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway
    • Leung D.W., Otomo C., Chory J., Rosen M.K. Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway. Proc Natl Acad Sci U S A 2008, 105:12797-12802.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 12797-12802
    • Leung, D.W.1    Otomo, C.2    Chory, J.3    Rosen, M.K.4
  • 26
    • 70350070364 scopus 로고    scopus 로고
    • Spatiotemporal control of cell signalling using a light-switchable protein interaction
    • Levskaya A., Weiner O.D., Lim W.A., Voigt C.A. Spatiotemporal control of cell signalling using a light-switchable protein interaction. Nature 2009, 461:997-1001.
    • (2009) Nature , vol.461 , pp. 997-1001
    • Levskaya, A.1    Weiner, O.D.2    Lim, W.A.3    Voigt, C.A.4
  • 27
    • 70349967637 scopus 로고    scopus 로고
    • Induction of protein-protein interactions in live cells using light
    • Yazawa M., Sadaghiani A.M., Hsueh B., Dolmetsch R.E. Induction of protein-protein interactions in live cells using light. Nat Biotechnol 2009, 27:941-945.
    • (2009) Nat Biotechnol , vol.27 , pp. 941-945
    • Yazawa, M.1    Sadaghiani, A.M.2    Hsueh, B.3    Dolmetsch, R.E.4
  • 29
    • 80053347082 scopus 로고    scopus 로고
    • Light-based feedback for controlling intracellular signaling dynamics
    • Toettcher J.E., Gong D., Lim W.A., Weiner O.D. Light-based feedback for controlling intracellular signaling dynamics. Nat Methods 2011, 8:837-839.
    • (2011) Nat Methods , vol.8 , pp. 837-839
    • Toettcher, J.E.1    Gong, D.2    Lim, W.A.3    Weiner, O.D.4
  • 31
    • 79959514813 scopus 로고    scopus 로고
    • A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice
    • Ye H., Baba M.D.E., Peng R.W., Fussenegger M. A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice. Science 2011, 332:1565-1568.
    • (2011) Science , vol.332 , pp. 1565-1568
    • Ye, H.1    Baba, M.D.E.2    Peng, R.W.3    Fussenegger, M.4
  • 32
    • 0037436155 scopus 로고    scopus 로고
    • Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms
    • Park S-H., Zarrinpar A., Lim W.A. Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms. Science 2003, 299:1061-1064.
    • (2003) Science , vol.299 , pp. 1061-1064
    • Park, S.-H.1    Zarrinpar, A.2    Lim, W.A.3
  • 34
    • 17644419994 scopus 로고    scopus 로고
    • Directed evolution of specific receptor-ligand pairs for use in the creation of gene switches
    • Chockalingam K., Chen Z., Katzenellenbogen J.A., Zhao H. Directed evolution of specific receptor-ligand pairs for use in the creation of gene switches. Proc Natl Acad Sci U S A 2005, 102:5691-5696.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 5691-5696
    • Chockalingam, K.1    Chen, Z.2    Katzenellenbogen, J.A.3    Zhao, H.4
  • 35
    • 34249894454 scopus 로고    scopus 로고
    • Rewiring cellular morphology pathways with synthetic guanine nucleotide exchange factors
    • Yeh B.J., Rutigliano R.J., Deb A., Bar-Sagi D., Lim W.A. Rewiring cellular morphology pathways with synthetic guanine nucleotide exchange factors. Nature 2007, 447:596-600.
    • (2007) Nature , vol.447 , pp. 596-600
    • Yeh, B.J.1    Rutigliano, R.J.2    Deb, A.3    Bar-Sagi, D.4    Lim, W.A.5
  • 36
    • 40849100220 scopus 로고    scopus 로고
    • Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics
    • Bashor C.J., Helman N.C., Yan S., Lim W.A. Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics. Science 2008, 319:1539-1543.
    • (2008) Science , vol.319 , pp. 1539-1543
    • Bashor, C.J.1    Helman, N.C.2    Yan, S.3    Lim, W.A.4
  • 38
    • 79953317810 scopus 로고    scopus 로고
    • Synthetic conversion of a graded receptor signal into a tunable, reversible switch
    • Palani S., Sarkar C.A. Synthetic conversion of a graded receptor signal into a tunable, reversible switch. Mol Syst Biol 2011, 7:480.
    • (2011) Mol Syst Biol , vol.7 , pp. 480
    • Palani, S.1    Sarkar, C.A.2
  • 39
    • 79959859399 scopus 로고    scopus 로고
    • Robust network topologies for generating switch-like cellular responses
    • Shah N.A., Sarkar C.A. Robust network topologies for generating switch-like cellular responses. PLoS Comput Biol 2011, 7:e1002085.
    • (2011) PLoS Comput Biol , vol.7
    • Shah, N.A.1    Sarkar, C.A.2
  • 40
    • 1942467023 scopus 로고    scopus 로고
    • Programmed population control by cell-cell communication and regulated killing
    • You L., Cox R.S., Weiss R., Arnold F.H. Programmed population control by cell-cell communication and regulated killing. Nature 2004, 428:868-871.
    • (2004) Nature , vol.428 , pp. 868-871
    • You, L.1    Cox, R.S.2    Weiss, R.3    Arnold, F.H.4
  • 41
    • 17844374314 scopus 로고    scopus 로고
    • A synthetic multicellular system for programmed pattern formation
    • Basu S., Gerchman Y., Collins C.H., Arnold F.H., Weiss R. A synthetic multicellular system for programmed pattern formation. Nature 2005, 434:1130-1134.
    • (2005) Nature , vol.434 , pp. 1130-1134
    • Basu, S.1    Gerchman, Y.2    Collins, C.H.3    Arnold, F.H.4    Weiss, R.5
  • 42
    • 28644440579 scopus 로고    scopus 로고
    • Artificial cell-cell communication in yeast Saccharomyces cerevisiae using signaling elements from Arabidopsis thaliana
    • Chen M.T., Weiss R. Artificial cell-cell communication in yeast Saccharomyces cerevisiae using signaling elements from Arabidopsis thaliana. Nat Biotechnol 2005, 23:1551-1555.
    • (2005) Nat Biotechnol , vol.23 , pp. 1551-1555
    • Chen, M.T.1    Weiss, R.2
  • 44
    • 63849290890 scopus 로고    scopus 로고
    • Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy
    • Lu T.K., Collins J.J. Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy. Proc Natl Acad Sci U S A 2009, 106:4629-4634.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 4629-4634
    • Lu, T.K.1    Collins, J.J.2
  • 46
    • 29144482539 scopus 로고    scopus 로고
    • Environmentally controlled invasion of cancer cells by engineered bacteria
    • Anderson J.C., Clarke E.J., Arkin A.P., Voigt C.A. Environmentally controlled invasion of cancer cells by engineered bacteria. J Mol Biol 2006, 355:619-627.
    • (2006) J Mol Biol , vol.355 , pp. 619-627
    • Anderson, J.C.1    Clarke, E.J.2    Arkin, A.P.3    Voigt, C.A.4
  • 47
    • 33745085925 scopus 로고    scopus 로고
    • Short hairpin RNA-expressing bacteria elicit RNA interference in mammals
    • Xiang S., Fruehauf J., Li C.J. Short hairpin RNA-expressing bacteria elicit RNA interference in mammals. Nat Biotechnol 2006, 24:697-702.
    • (2006) Nat Biotechnol , vol.24 , pp. 697-702
    • Xiang, S.1    Fruehauf, J.2    Li, C.J.3
  • 48
    • 80052456127 scopus 로고    scopus 로고
    • Multi-input RNAi-based logic circuit for identification of specific cancer cells
    • Xie Z., Wroblewska L., Prochazka L., Weiss R., Benenson Y. Multi-input RNAi-based logic circuit for identification of specific cancer cells. Science 2011, 333:1307-1311.
    • (2011) Science , vol.333 , pp. 1307-1311
    • Xie, Z.1    Wroblewska, L.2    Prochazka, L.3    Weiss, R.4    Benenson, Y.5
  • 50
    • 68749118345 scopus 로고    scopus 로고
    • Defining network topologies that can achieve biochemical adaptation
    • Ma W., Trusina A., El-Samad H., Lim W.A., Tang C. Defining network topologies that can achieve biochemical adaptation. Cell 2009, 138:760-773.
    • (2009) Cell , vol.138 , pp. 760-773
    • Ma, W.1    Trusina, A.2    El-Samad, H.3    Lim, W.A.4    Tang, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.