Engineering synthetic signaling proteins with ultrasensitive input/output control

Nature Biotechnology

Volumn 25, Issue 6, 2007, Pages 660-662

  Dueber, John E ^a,d,e   Mirsky, Ethan A ^a,d   Lim, Wendell A ^b,c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UCSF UC Berkeley Nanomedicine Development Center   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVITY; BIOTECHNOLOGY; SIGNAL PROCESSING;

LINEAR SIGNALING PROTEINS; MODULAR AUTOINHIBITORY INTERACTIONS; SYNTHETIC SIGNALING PROTEINS; ULTRASENSITIVE INPUT/OUTPUT CONTROL;

PROTEINS;

ACTIN; GLYCINE; LIGAND; PROTEIN SH3; SERINE;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BIOENGINEERING; BIOLOGICAL ACTIVITY; GEL FILTRATION; INHIBITION KINETICS; NONLINEAR SYSTEM; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN SYNTHESIS; SIGNAL PROCESSING;

ALGORITHMS; COMPUTER SIMULATION; FEEDBACK; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; PROTEIN ENGINEERING; SIGNAL TRANSDUCTION;

EID: 34249885757     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt1308     Document Type: Article

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