A synthetic-natural hybrid oscillator in human cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 39, 2010, Pages 17047-17052

  Toettcher, Jared E ^a,b   Mock, Caroline ^a   Batchelor, Eric ^a   Loewer, Alexander ^a   Lahav, Galit ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b USA   (United States)

Author keywords

Live cell imaging; Mathematical modeling; Oscillations; Systems biology

Indexed keywords

NUTLIN 3; PROTEIN MDM2; PROTEIN P53; ZINC; MDM2 PROTEIN, HUMAN;

AMPLITUDE MODULATION; ARTICLE; CELL INTERACTION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MAMMAL CELL; MATHEMATICAL MODEL; NEGATIVE FEEDBACK; OSCILLATOR; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; BIOLOGICAL MODEL; COMPUTER SIMULATION; FEEDBACK SYSTEM; GENETICS; METABOLISM; TUMOR CELL LINE;

MAMMALIA;

CELL LINE, TUMOR; COMPUTER SIMULATION; FEEDBACK, PHYSIOLOGICAL; HUMANS; METABOLIC NETWORKS AND PATHWAYS; MODELS, BIOLOGICAL; PROTO-ONCOGENE PROTEINS C-MDM2; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 78049239445     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1005615107     Document Type: Article

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