Vasomotor response to cold stimulation in human capsaicin-induced hyperalgesic area

Experimental Brain Research

Volumn 164, Issue 3, 2005, Pages 334-340

  Pud, Dorit ^a,b   Andersen, Ole Kæseler ^c   Arendt Nielsen, Lars ^c   Eisenberg, Elon ^b,d   Yarnitsky, David ^b,d  

^a UNIVERSITY OF HAIFA   (Israel)

^b Haifa Medical Center Rothschild   (Israel)

^c AALBORG UNIVERSITY   (Denmark)

^d RAMBAM MEDICAL CENTER   (Israel)

Author keywords

Capsaicin; Cold stimulation; Laser Doppler flowmetry; Vasoconstriction; Vasodilatation

Indexed keywords

CAPSAICIN;

ADULT; ARTICLE; BLOOD FLOW; COLD; FEMALE; FOREARM; HUMAN; HYPERALGESIA; INFLAMMATION; INJECTION SITE; LOW TEMPERATURE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SKIN TEMPERATURE; VASOCONSTRICTION; VASODILATATION; VASOMOTOR REFLEX;

ADULT; ANALYSIS OF VARIANCE; CAPSAICIN; COLD; FEMALE; HUMANS; HYPERALGESIA; LASER-DOPPLER FLOWMETRY; MALE; PAIN MEASUREMENT; SKIN; SKIN TEMPERATURE; TIME FACTORS; VASOCONSTRICTION; VASODILATION;

EID: 23744481023     PISSN: 00144819     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00221-005-2254-5     Document Type: Article

References (34)

1. Andersen OK, Yucel A, Arendt-Nielsen L (2001) Human models of hyperalgesia induced by capsaicin: a discussion of secondary hyperalgesia to heat. In: Harden RN, Baron R, Janig W (eds) Complex regional pain syndrome. IASP Press, Seattle, pp 165-181
2. Cervero F, Laird JMA (1996) Mechanisms of allodynia: interactions between sensitive mechanoreceptors and nociceptors. Neuroreport 7:526-528
3. Cervero F, Laird JMA, Garcia-Nicas E (2003) Secondary hyperalgesia and presynaptic inhibition: an update. Eur J Pain 7:345-351
4. Daanen HAM (2003) Finger cold-induced vasodilatation: a review. Eur J Appl Physiol 89:411-426
5. Davies JWL (1982) Prompt cooling of burned areas: a review of benefits and the effector mechanisms. Burns 9:1-6
6. Davis KD, Pope GE (2002) Noxious cold evokes multiple sensations with distinct time courses. Pain 98:179-185
7. Forster C, Greiner T, Nischik M, Schmelz M, Handwerker HO (1995) Neurogenic flare responses are heterogeneous in superficial and deep layers of human skin. Neurosci Lett 185:33-36
8. Francis JE, Rogli R, Love TJ, Robinson CP (1979) Thermography as a means of blood perfusion measurement. J Biomech Eng 101:246-249
9. Garcia-Nicas E, Laird JMA, Cervero F (2001) Vasodilatation in hyperalgesic rat skin evoked by stimulation of afferent Aδ fibers: further evidence for a role of dorsal root reflexes in allodynia. Pain 94:283-291
10. Häbler HJ, Wasner G, Janig W (1997) Interaction of sympathetic vasoconstriction and antidromic vasodilatation in the control of skin blood flow. Exp Brain Res 113:402-410
11. Hornyak ME, Naver HK, Rydenhag B, Wallin BG (1990) Sympathetic activity influences the vascular axon reflex in the skin. Acta Physiol Scan 139:77-84
12. Kawamata M, Takahashi T, Kozuka Y, Nawa Y, Nishukawa K, Narimatsu E, Watanabe H, Namiki A (2002) Experimental incision induced pain in human skin: effects of systemic lidocaine on flare formation and hyperalgesia. Pain 100:77-89
13. Klede M, Handwerker HO, Schmelz M (2003) Central origin of secondary mechanical hyperalgesia. J Neurophysiol 90:353-359
14. Koppert W, Zeck S, Blunk JA, Schmelz M, Likar R, Sittl R (1999) The effects of intradermal fentanyl and ketamine on capsaicin induced secondary hyperalgesia and flare reaction. Anesth Analg 89:1521-1527
15. Koppert W, Dern SK, Sittl R, Albrecht S, Schuttler J, Schelz M (2001) A new model of electrically evoked pain and hyperalgesia in human skin. Anesthesiology 95:395-402
16. Kreh A, Anton F, Gilly H, Handwerker HO (1984) Vascular reactions correlated with pain due to cold. Exp Neurol 85:533546
17. Kurvers HA, Tangelder GJ, De Mey JG, Slaaf DW, Beuk RJ, van den Wildenberg FA, Kitslaar PJ, Reneman RS, Jacobs MJ (1997) Skin blood flow abnormalities in a rat model of neuropathic pain: result of decreased sympathetic vasoconstrictor outflow? J Auton Nerv Syst 63:19-29
18. Lewis T (1930) Observations upon the reactions of the vessels of the human skin to cold. Heart 15:177-208
19. Magerl W., Szolcsanyi J., Westerman RA., Handwerker HO (1987) Laser Doppler measurements of skin vasodilation elicited by percutaneous electrical stimulation of nociceptors in humans. Neurosci Lett 82:349-354
20. Mohammadian P, Andersen OK, Arendt-Nielsen L (1998) Correlation between local vascular and sensory changes following tissue inflammation induced by repetitive application of topical capsaicin. Brain Res 792:1-9
21. Nilsson AL, Eriksson LEW, Nilsson GE (1986) Effects of local convective cooling and rewarming on skin blood flow. Int J Microcirc Clin Exp 5:11-25
22. Ochoa JL, Yarnitsky D, Marchettini P, Dotson R, Cline M (1993) Interactions between sympathetic vasoconstrictor outflow and C nociceptor induced antidromic vasodilatation. Pain 54:191-196
23. Paintal AS (1971) The responses of chemoreceptors at reduced temperatures. J Physiol 217:1-18
24. Quinn AG, McLelland J, Essex T, Farr PM (1991) Measurement of cutaneous inflammatory reactions using a scanning laser Doppler velocimeter. Br J Dermatol 125:30-37
25. Sato A, Schmidt RF (1973) Somatosympathetic reflexes: afferent fibers, central pathways, discharge characteristics. Physiol Rev 53:916-947
26. Sendowski I, Savourey G, Besnard Y, Bittel J (1997) Cold induced vasodilatation and cardiovascular responses in humans during cold water immersion of various upper limb areas. Eur J Appl Physiol 75:471-477
27. Serra J, Campero M, Ochoa J (1998) Flare and hyperalgesia after intradermal capsaicin injection in human skin. J Neurophysiol 80:2801-2810
28. Simone DA, Ngeow JY, Putterman GJ, LaMotte RH (1987) Hyperalgesia to heat after intradermal injection of capsaicin. Brain Res 418:201-203
29. Sumikura H, Andersen OK, Drewes AM, Arendt-Nielsen L (2003a) Spatial and temporal profiles of flare and hyperalgesia after intradermal capsaicin. Pain 105:285-291
30. Sumikura H, Andersen OK, Drewes AM, Arendt-Nielsen L (2003b) A comparison of hyperalgesia and neurogenic inflammation induced by melittin and capsaicin in humans. Neurosci Lett 337:147-150
31. Szolcsànyi J (1988) Antidromic vasodilatation and neurogenic inflammation. Agents Actions 23:4-11
32. Wasner G, Schattschneider J, Baron R (2002) Skin temperature side diflerences - a diagnostic tool for CRPS? Pain 98:19-26
33. Wasner G, Schattschneider J, Binder A, Baron R (2004) Topical menthol - a human model for cold pain by activation and sensitization of C nociceptors. Brain 127:1159-1171
34. Yarnitsky D, Eisenberg E (1998) Neuropathic pain: between positive and negative ends. Pain Forum 7:241-242