Histamine H 4 receptor antagonists as potent modulators of mammalian vestibular primary neuron excitability

British Journal of Pharmacology

Volumn 167, Issue 4, 2012, Pages 905-916

  Desmadryl, G ^a   Gaboyard Niay, S ^a   Brugeaud, A ^b   Travo, C ^a   Broussy, A ^b   Saleur, A ^b   Dyhrfjeld Johnsen, J ^a   Wersinger, E ^b   Chabbert, C ^a  

^a HÔPITAL SAINT ELOI   (France)

^b Pépinière Cap Alpha   (France)

Author keywords

antagonists; histamine H 4 receptor; in vitro electrophysiology; vestibular disorders; vestibular primary neurons

Indexed keywords

1 (5 CHLORO 2 BENZIMIDAZOLYLCARBONYL) 4 METHYLPIPERAZINE; 1 (5 CHLORO 2 INDOLYLCARBONYL) 4 METHYLPIPERAZINE; 4 METHYLHISTAMINE; BETAHISTINE; HISTAMINE H3 RECEPTOR; HISTAMINE H4 RECEPTOR; THIOPERAMIDE; 1 ((5 CHLORO 1H INDOL 2 YL)CARBONYL) 4 METHYLPIPERAZINE; 1-((5-CHLORO-1H-INDOL-2-YL)CARBONYL)-4-METHYLPIPERAZINE; ANTIHISTAMINIC AGENT; BENZIMIDAZOLE DERIVATIVE; G PROTEIN COUPLED RECEPTOR; HISTAMINE AGONIST; HISTAMINE H3 RECEPTOR ANTAGONIST; HISTAMINE RECEPTOR; HRH4 PROTEIN, RAT; INDOLE DERIVATIVE; PIPERAZINE DERIVATIVE; PIPERIDINE DERIVATIVE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG TARGETING; FEMALE; GANGLION; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MOLECULAR CLONING; NERVE CELL EXCITABILITY; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE POTENTIAL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEUROMODULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VESTIBULAR DISORDER; VESTIBULAR NERVE; WHOLE CELL; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT; LONG EVANS RAT; NERVE CELL; PHYSIOLOGY; WISTAR RAT;

ANIMALS; BENZIMIDAZOLES; BETAHISTINE; CELLS, CULTURED; FEMALE; HISTAMINE AGONISTS; HISTAMINE ANTAGONISTS; HISTAMINE H3 ANTAGONISTS; INDOLES; NEURONS; PIPERAZINES; PIPERIDINES; RATS; RATS, LONG-EVANS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE; VESTIBULAR NERVE;

EID: 84867022895     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2012.02049.x     Document Type: Article

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