Conformational changes in the M2 muscarinic receptor induced by membrane voltage and agonist binding

Journal of Physiology

Volumn 589, Issue 7, 2011, Pages 1741-1753

  Navarro Polanco, Ricardo A ^a   Galindo, Eloy G Moreno ^a   Ferrer Villada, Tania ^b   Arias, Marcelo ^b   Rigby, J Ryan ^b   Sánchez Chapula, José A ^a   Tristani Firouzi, Martin ^b  

^a UNIVERSIDAD DE COLIMA   (Mexico)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; MUSCARINIC M2 RECEPTOR; MUSCARINIC M2 RECEPTOR AGONIST; PILOCARPINE;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE DEPOLARIZATION; CELLULAR DISTRIBUTION; CHANNEL GATING; CHOLINERGIC ACTIVITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG BINDING SITE; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; HEART ATRIUM; HEART MUSCLE CELL; HUMAN; HUMAN CELL; LIGAND BINDING; MEMBRANE POTENTIAL; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; SIGNAL TRANSDUCTION;

ACETYLCHOLINE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CATS; FEMALE; HEK293 CELLS; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; MODELS, MOLECULAR; MUSCARINIC AGONISTS; MUTAGENESIS, SITE-DIRECTED; MYOCYTES, CARDIAC; OOCYTES; PATCH-CLAMP TECHNIQUES; PILOCARPINE; PROTEIN CONFORMATION; RECEPTOR, MUSCARINIC M2; RECOMBINANT PROTEINS;

EID: 79953156424     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.204107     Document Type: Article

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