메뉴 건너뛰기




Volumn 14, Issue 4, 1999, Pages 232-238

MMP inhibitors: Experimental and clinical studies

Author keywords

Markers; Metalloproteases; MMP inhibitors

Indexed keywords

4 DEDIMETHYLAMINOSANCYCLINE; BATIMASTAT; CARBOPLATIN; CGS 27023A; CYTOTOXIC AGENT; DOXORUBICIN; FLUOROURACIL; FOLINIC ACID; MARIMASTAT; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; PACLITAXEL; PRINOMASTAT; TANOMASTAT;

EID: 0033388462     PISSN: 03936155     EISSN: None     Source Type: Journal    
DOI: 10.1177/172460089901400406     Document Type: Conference Paper
Times cited : (38)

References (64)
  • 2
    • 0025847582 scopus 로고
    • Matrix metalloproteinases and their inhibitor in connective tissue remodeling
    • Woessner JF Jr. Matrix metalloproteinases and their inhibitor in connective tissue remodeling. FASEB J 1991; 5: 2145-54.
    • (1991) FASEB J , vol.5 , pp. 2145-2154
    • Woessner J.F., Jr.1
  • 3
    • 0027683226 scopus 로고
    • Structural biochemistry and activation of matrix metalloproteases
    • Kleiner DEJ, Stetler-Stevenson WG. Structural biochemistry and activation of matrix metalloproteases. Curr Opin Cell Biol 1993; 5: 891-7.
    • (1993) Curr Opin Cell Biol , vol.5 , pp. 891-897
    • Kleiner, D.E.J.1    Stetler-Stevenson, W.G.2
  • 4
    • 0024985361 scopus 로고
    • Growth factor-regulated proteases and extracellular matrix remodeling during mammalian development
    • Matrisian LM, Hogan BL. Growth factor-regulated proteases and extracellular matrix remodeling during mammalian development. Curr Top Dev Biol 1990; 24: 219-59.
    • (1990) Curr Top Dev Biol , vol.24 , pp. 219-259
    • Matrisian, L.M.1    Hogan, B.L.2
  • 5
    • 0026890915 scopus 로고
    • Cytokines and proteases in invasive processes: Molecular similarities between inflammation and cancer
    • Opdenakker G, Van Damme J. Cytokines and proteases in invasive processes: molecular similarities between inflammation and cancer. Cytokine 1992; 4: 251-8.
    • (1992) Cytokine , vol.4 , pp. 251-258
    • Opdenakker, G.1    Van Damme, J.2
  • 6
    • 0027768570 scopus 로고
    • Cytokine regulation of metalloproteinase gene expression
    • Mauviel A. Cytokine regulation of metalloproteinase gene expression. J Cell Biochem 1993; 53: 288-95.
    • (1993) J Cell Biochem , vol.53 , pp. 288-295
    • Mauviel, A.1
  • 7
    • 0022982416 scopus 로고
    • Isolation of the oncogene and epidermal growth factor-induced transin gene: Complex control in rat fibroblasts
    • Matrisian LM, Leroy P, Ruhlmann C, Gesnel MC, Breathnach R. Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts. Molec Cell Biol 1986; 6: 1679-86.
    • (1986) Molec Cell Biol , vol.6 , pp. 1679-1686
    • Matrisian, L.M.1    Leroy, P.2    Ruhlmann, C.3    Gesnel, M.C.4    Breathnach, R.5
  • 8
    • 0025866180 scopus 로고
    • Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression
    • Overall CM, Wrana JL, Sodek J. Transcriptional and post-transcriptional regulation of 72-kDa gelatinase/type IV collagenase by transforming growth factor-beta 1 in human fibroblasts. Comparisons with collagenase and tissue inhibitor of matrix metalloproteinase gene expression. J Biol Chem 1991; 266: 14064-71.
    • (1991) J Biol Chem , vol.266 , pp. 14064-14071
    • Overall, C.M.1    Wrana, J.L.2    Sodek, J.3
  • 9
    • 0026714363 scopus 로고
    • Post-transcriptional regulation of collagenase and stromelysin gene expression by epidermal growth factor and dexamethasone in cultured human fibroblasts
    • Delany AM, Brinckerhoff CE. Post-transcriptional regulation of collagenase and stromelysin gene expression by epidermal growth factor and dexamethasone in cultured human fibroblasts. J Cell Biochem 1992; 50: 400-10.
    • (1992) J Cell Biochem , vol.50 , pp. 400-410
    • Delany, A.M.1    Brinckerhoff, C.E.2
  • 11
    • 0028907318 scopus 로고
    • Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease
    • Strongin AY, Collier I, Bannikov G, Marmer BL, Grant GA, Goldberg GI. Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J Biol Chem 1995; 270: 5331-8.
    • (1995) J Biol Chem , vol.270 , pp. 5331-5338
    • Strongin, A.Y.1    Collier, I.2    Bannikov, G.3    Marmer, B.L.4    Grant, G.A.5    Goldberg, G.I.6
  • 12
    • 0029594498 scopus 로고
    • Contributions of tumors and stromal matrix metalloproteinases to tumor progression, invasion and metastasis
    • MacDougall JR, Matrisian LM. Contributions of tumors and stromal matrix metalloproteinases to tumor progression, invasion and metastasis. Cancer Metastasis Rev 1995; 14: 351-62.
    • (1995) Cancer Metastasis Rev , vol.14 , pp. 351-362
    • MacDougall, J.R.1    Matrisian, L.M.2
  • 13
    • 0030715322 scopus 로고    scopus 로고
    • ECM and cell surface proteolysis: Regulating cellular ecology
    • Werb Z. ECM and cell surface proteolysis: regulating cellular ecology. Cell 1997; 91: 439-42.
    • (1997) Cell , vol.91 , pp. 439-442
    • Werb, Z.1
  • 14
    • 0032493871 scopus 로고    scopus 로고
    • Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay
    • Kim J, Yu W, Kovalski K, Ossowski L. Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay. Cell 1998; 94: 353-62.
    • (1998) Cell , vol.94 , pp. 353-362
    • Kim, J.1    Yu, W.2    Kovalski, K.3    Ossowski, L.4
  • 15
    • 0027451998 scopus 로고
    • Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production
    • Azzam HS, Arand G, Lippman ME, Thompson EW. Association of MMP-2 activation potential with metastatic progression in human breast cancer cell lines independent of MMP-2 production. J Natl Cancer Inst 1993; 85: 1758-64.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 1758-1764
    • Azzam, H.S.1    Arand, G.2    Lippman, M.E.3    Thompson, E.W.4
  • 16
    • 0029876376 scopus 로고    scopus 로고
    • The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases
    • Whitelock JM, Murdoch AD, Iozzo RV, Underwood PA. The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases. J Biol Chem 1996; 271: 10079-86.
    • (1996) J Biol Chem , vol.271 , pp. 10079-10086
    • Whitelock, J.M.1    Murdoch, A.D.2    Iozzo, R.V.3    Underwood, P.A.4
  • 17
    • 0030806173 scopus 로고    scopus 로고
    • Changing views of the role of matrix metalloproteinases in metastasis
    • Chambers AF, Matrisian LM. Changing views of the role of matrix metalloproteinases in metastasis. J Natl Cancer Inst 1997; 89: 1260-70.
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1260-1270
    • Chambers, A.F.1    Matrisian, L.M.2
  • 18
    • 0030044480 scopus 로고    scopus 로고
    • Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer
    • Liabakk NB, Talbot I, Smith RA, Wilkinson K, Balkwill F. Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer. Cancer Res 1996; 56: 190-6.
    • (1996) Cancer Res , vol.56 , pp. 190-196
    • Liabakk, N.B.1    Talbot, I.2    Smith, R.A.3    Wilkinson, K.4    Balkwill, F.5
  • 19
    • 0027469921 scopus 로고
    • Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma
    • Brown PD, Bloxidge RE, Stuart NS, Gatter KC, Carmichael J. Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma. J Natl Cancer Inst 1993; 85: 574-8.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 574-578
    • Brown, P.D.1    Bloxidge, R.E.2    Stuart, N.S.3    Gatter, K.C.4    Carmichael, J.5
  • 20
    • 0032570712 scopus 로고    scopus 로고
    • Active and tissue inhibitor of matrix metalloproteinase-free gelatinase B accumulates within human microvascular endothelial vesicles
    • Nguyen M, Arkell J, Jackson CJ. Active and tissue inhibitor of matrix metalloproteinase-free gelatinase B accumulates within human microvascular endothelial vesicles. J Biol Chem 1998; 273: 5400-4.
    • (1998) J Biol Chem , vol.273 , pp. 5400-5404
    • Nguyen, M.1    Arkell, J.2    Jackson, C.J.3
  • 21
    • 0029080314 scopus 로고
    • Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer
    • Gress TM, Muller-Pillasch F, Lerch MM, Friess H, Buchler M, Adler G. Expression and in-situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer. Int J Cancer 1995; 62: 407-13.
    • (1995) Int J Cancer , vol.62 , pp. 407-413
    • Gress, T.M.1    Muller-Pillasch, F.2    Lerch, M.M.3    Friess, H.4    Buchler, M.5    Adler, G.6
  • 22
    • 0030882679 scopus 로고    scopus 로고
    • Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma
    • Fishman DA, Bafetti LM, Banionis S, Kearns AS, Chilukuri K, Stack MS. Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma. Cancer 1997; 80: 1457-63.
    • (1997) Cancer , vol.80 , pp. 1457-1463
    • Fishman, D.A.1    Bafetti, L.M.2    Banionis, S.3    Kearns, A.S.4    Chilukuri, K.5    Stack, M.S.6
  • 23
    • 0031909775 scopus 로고    scopus 로고
    • MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: Possible implications for the role of desmoplastic fibroblasts
    • Afzal S, Lalani EN, Poulsom R, et al. MT1-MMP and MMP-2 mRNA expression in human ovarian tumors: possible implications for the role of desmoplastic fibroblasts. Human Pathol 1998; 29: 155-65.
    • (1998) Human Pathol , vol.29 , pp. 155-165
    • Afzal, S.1    Lalani, E.N.2    Poulsom, R.3
  • 24
    • 0028178968 scopus 로고
    • Expression and activity of MMPs and their regulators in ovarian cancer
    • Naylor MS, Stamp GW, Davies BD, Balkwill FR. Expression and activity of MMPs and their regulators in ovarian cancer. Int J Cancer 1994; 58: 50-6.
    • (1994) Int J Cancer , vol.58 , pp. 50-56
    • Naylor, M.S.1    Stamp, G.W.2    Davies, B.D.3    Balkwill, F.R.4
  • 25
    • 0040351696 scopus 로고    scopus 로고
    • Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions
    • Uria JA, Stahle-Backdahl M, Seiki M, Fueyo A, Lopez-Otin C. Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions. Cancer Res 1997; 57: 4882-8.
    • (1997) Cancer Res , vol.57 , pp. 4882-4888
    • Uria, J.A.1    Stahle-Backdahl, M.2    Seiki, M.3    Fueyo, A.4    Lopez-Otin, C.5
  • 26
    • 0030694894 scopus 로고    scopus 로고
    • Fibronectin secretion from human peritoneal tissue induces Mr 92,000 type IV collagenase expression and invasion in ovarian cancer cell lines
    • Shibata K, Kikkawa F, Nawa A, Suganuma N, Hamaguchi M. Fibronectin secretion from human peritoneal tissue induces Mr 92,000 type IV collagenase expression and invasion in ovarian cancer cell lines. Cancer Res 1997; 57: 5416-20.
    • (1997) Cancer Res , vol.57 , pp. 5416-5420
    • Shibata, K.1    Kikkawa, F.2    Nawa, A.3    Suganuma, N.4    Hamaguchi, M.5
  • 27
    • 0029586589 scopus 로고
    • Matrix metalloproteinase inhibition: A review of anti-tumor activity
    • Brown PD, Giavazzi R. Matrix metalloproteinase inhibition: A review of anti-tumor activity. Ann Oncol 1995; 6: 967-74.
    • (1995) Ann Oncol , vol.6 , pp. 967-974
    • Brown, P.D.1    Giavazzi, R.2
  • 28
    • 0028651852 scopus 로고
    • Clinical trials of a low molecular weight matrix metalloproteinase inhibitor in cancer
    • Brown PD. Clinical trials of a low molecular weight matrix metalloproteinase inhibitor in cancer. Ann NY Acad Sci 1994; 732: 217-21.
    • (1994) Ann NY Acad Sci , vol.732 , pp. 217-221
    • Brown, P.D.1
  • 29
    • 8044250278 scopus 로고    scopus 로고
    • Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha
    • Moss ML, Jin SL, Milla ME, et al. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha. Nature 1997; 385: 733-6.
    • (1997) Nature , vol.385 , pp. 733-736
    • Moss, M.L.1    Jin, S.L.2    Milla, M.E.3
  • 30
    • 8044257704 scopus 로고    scopus 로고
    • A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells
    • Black RA, Rauch CT, Kozlosky CJ, et al. A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 1997; 385: 729-33.
    • (1997) Nature , vol.385 , pp. 729-733
    • Black, R.A.1    Rauch, C.T.2    Kozlosky, C.J.3
  • 31
    • 0031450585 scopus 로고    scopus 로고
    • Bioactive conformation of a potent stromelysin inhibitor determined by X-nucleus filtered and multidimensional NMR spectroscopy
    • Gonnella NC, Li YC, Zhang X, Paris CG. Bioactive conformation of a potent stromelysin inhibitor determined by X-nucleus filtered and multidimensional NMR spectroscopy. Bioorg Med Chem 1997; 5: 2193-201.
    • (1997) Bioorg Med Chem , vol.5 , pp. 2193-2201
    • Gonnella, N.C.1    Li, Y.C.2    Zhang, X.3    Paris, C.G.4
  • 32
    • 0001419988 scopus 로고    scopus 로고
    • BAY 12-9566, a novel, biphenyl matrix metalloproteinase inhibitor, demonstrates anti-invasive and anti-angiogenic properties
    • Hibner B, Card A, Flynn C, et al. BAY 12-9566, a novel, biphenyl matrix metalloproteinase inhibitor, demonstrates anti-invasive and anti-angiogenic properties. Proc Am Ass Cancer Res 1998; 39: 302.
    • (1998) Proc Am Ass Cancer Res , vol.39 , pp. 302
    • Hibner, B.1    Card, A.2    Flynn, C.3
  • 33
    • 0028129059 scopus 로고
    • Inhibition of the metastatic spread and growth of B16-B16 murine melanoma by a synthetic matrix metalloproteinase inhibitor
    • Chirivi R, Garofalo A, Crimmin MJ, et al. Inhibition of the metastatic spread and growth of B16-B16 murine melanoma by a synthetic matrix metalloproteinase inhibitor. Int J Cancer 1994; 58: 460-4.
    • (1994) Int J Cancer , vol.58 , pp. 460-464
    • Chirivi, R.1    Garofalo, A.2    Crimmin, M.J.3
  • 34
    • 0028939303 scopus 로고
    • Inhibition of angiogenesis and murine hemangioma growth by batimastat, a synthetic inhibitor of matrix metalloproteinases
    • Taraboletti G, Garofalo A, Belotti D, et al. Inhibition of angiogenesis and murine hemangioma growth by batimastat, a synthetic inhibitor of matrix metalloproteinases. J Natl Cancer Inst 1995; 87: 293-8.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 293-298
    • Taraboletti, G.1    Garofalo, A.2    Belotti, D.3
  • 35
    • 0028889359 scopus 로고
    • Effect of matrix metalloproteinase inhibitor batimastat on breast cancer regrowth and metastasis in athymic mice
    • Sledge GWJ, Qulali M, Goulet R, Bone EA, Fife R. Effect of matrix metalloproteinase inhibitor batimastat on breast cancer regrowth and metastasis in athymic mice. J Natl Cancer Inst 1995; 87: 1546-50.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1546-1550
    • Sledge, G.W.J.1    Qulali, M.2    Goulet, R.3    Bone, E.A.4    Fife, R.5
  • 36
    • 0029165411 scopus 로고
    • Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models
    • Watson SA, Morris TM, Robinson G, Crimmin MJ, Brown PD, Hardcastle JD. Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models. Cancer Res 1995; 55: 3629-33.
    • (1995) Cancer Res , vol.55 , pp. 3629-3633
    • Watson, S.A.1    Morris, T.M.2    Robinson, G.3    Crimmin, M.J.4    Brown, P.D.5    Hardcastle, J.D.6
  • 37
    • 0027994031 scopus 로고
    • Matrix metalloproteinase inhibitor BB-94 (batimastat) inhibits human colon tumour growth and spread in a patient-like orthotopic model in nude mice
    • Wang X, Fu X, Brown PD, Crimmin MJ, Hoffman RM. Matrix metalloproteinase inhibitor BB-94 (batimastat) inhibits human colon tumour growth and spread in a patient-like orthotopic model in nude mice. Cancer Res 1994; 54: 4726-8.
    • (1994) Cancer Res , vol.54 , pp. 4726-4728
    • Wang, X.1    Fu, X.2    Brown, P.D.3    Crimmin, M.J.4    Hoffman, R.M.5
  • 38
    • 0027251836 scopus 로고
    • A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts
    • Davies B, Brown PD, East N, Crimmin MJ, Balkwill FR. A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts. Cancer Res 1993; 53:2087-91.
    • (1993) Cancer Res , vol.53 , pp. 2087-2091
    • Davies, B.1    Brown, P.D.2    East, N.3    Crimmin, M.J.4    Balkwill, F.R.5
  • 39
    • 0031945505 scopus 로고    scopus 로고
    • Batimastat, a synthetic inhibitor of matrix metalloproteinases, potentiates the antitumor activity of cisplatin in ovarian carcinoma xenografts
    • Giavazzi R, Garofalo A, Ferri C, et al. Batimastat, a synthetic inhibitor of matrix metalloproteinases, potentiates the antitumor activity of cisplatin in ovarian carcinoma xenografts. Clin Cancer Res 1998; 4: 985-92.
    • (1998) Clin Cancer Res , vol.4 , pp. 985-992
    • Giavazzi, R.1    Garofalo, A.2    Ferri, C.3
  • 40
    • 0031848158 scopus 로고    scopus 로고
    • Phase I study of intraperitoneal metalloproteinase inhibitor BB94 in patients with malignant ascites
    • Beattie GJ, Smyth G.J., Smyth JF. Phase I study of intraperitoneal metalloproteinase inhibitor BB94 in patients with malignant ascites. Clin Cancer Res 1998; 4: 1899-902.
    • (1998) Clin Cancer Res , vol.4 , pp. 1899-1902
    • Beattie, G.J.1    Smyth, G.J.2    Smyth, J.F.3
  • 41
    • 0031776982 scopus 로고    scopus 로고
    • Phase I trial of marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancer
    • Praga-Wojtowicz S, Torri J, Johnson M, et al. Phase I trial of marimastat, a novel matrix metalloproteinase inhibitor, administered orally to patients with advanced lung cancer. J Clin Oncol 1998; 16: 2150-6.
    • (1998) J Clin Oncol , vol.16 , pp. 2150-2156
    • Praga-Wojtowicz, S.1    Torri, J.2    Johnson, M.3
  • 42
    • 0000823543 scopus 로고    scopus 로고
    • Anti-metastatic activity of BAY12-9566 in a human colon carcinoma HCT116 orthotopic model
    • abstract
    • Flynn C, Bull C, Eberwein D, Matherne C, Hibner B. Anti-metastatic activity of BAY12-9566 in a human colon carcinoma HCT116 orthotopic model. Proc Am Ass Cancer Res 1998; 39: 301 (abstract).
    • (1998) Proc Am Ass Cancer Res , vol.39 , pp. 301
    • Flynn, C.1    Bull, C.2    Eberwein, D.3    Matherne, C.4    Hibner, B.5
  • 43
    • 0001419989 scopus 로고    scopus 로고
    • Activity of the biphenyl matrix metalloproteinase inhibitor BAY12-9566 in murine in vivo models
    • abstract
    • Bull C, Flynn C, Eberwein D, Casazza AM, Carter CA, Hibner B. Activity of the biphenyl matrix metalloproteinase inhibitor BAY12-9566 in murine in vivo models. Proc Am Ass Cancer Res 1998; 39: 302 (abstract).
    • (1998) Proc Am Ass Cancer Res , vol.39 , pp. 302
    • Bull, C.1    Flynn, C.2    Eberwein, D.3    Casazza, A.M.4    Carter, C.A.5    Hibner, B.6
  • 44
    • 0032710567 scopus 로고    scopus 로고
    • BAY-12-9566, a novel inhibitor of matrix metalloproteinases with antiangiogenic activity
    • in press
    • Gatto C, Rieppi M, Borsotti P, et al. BAY-12-9566, a novel inhibitor of matrix metalloproteinases with antiangiogenic activity. Clin Cancer Res 1999; (in press).
    • (1999) Clin Cancer Res
    • Gatto, C.1    Rieppi, M.2    Borsotti, P.3
  • 45
    • 0000976105 scopus 로고    scopus 로고
    • Phase I study of the matrix metalloprotease inhibitor (MMPi) BAY12-9566 in patients with advanced cancer
    • abstract
    • Hirte H, Goel R, Bennet K, Elias I, Shah A, Seymour L. Phase I study of the matrix metalloprotease inhibitor (MMPI) BAY12-9566 in patients with advanced cancer. Ann Oncol 1998; 9 (Suppl 2): 75 (abstract).
    • (1998) Ann Oncol , vol.9 , Issue.SUPPL. 2 , pp. 75
    • Hirte, H.1    Goel, R.2    Bennet, K.3    Elias, I.4    Shah, A.5    Seymour, L.6
  • 46
    • 0000993867 scopus 로고    scopus 로고
    • A phase I and pharmacokinetic study of the oral matrix metalloprotein-ase inhibitor Bay-129566 in combination with paclitaxel and carboplatin
    • abstract
    • Tolcher A, Rowinsky EK, Rizzo J, et al. A phase I and pharmacokinetic study of the oral matrix metalloprotein-ase inhibitor Bay-129566 in combination with paclitaxel and carboplatin. Proc ASCO 1999; 18: 160a (abstract).
    • (1999) Proc ASCO , vol.18
    • Tolcher, A.1    Rowinsky, E.K.2    Rizzo, J.3
  • 47
    • 0032837028 scopus 로고    scopus 로고
    • Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials
    • Shalinsky DR, Brekken J, Zou H, et al. Broad antitumor and antiangiogenic activities of AG3340, a potent and selective MMP inhibitor undergoing advanced oncology clinical trials. Ann NY Acad Sci 1999; 878: 236-70.
    • (1999) Ann NY Acad Sci , vol.878 , pp. 236-270
    • Shalinsky, D.R.1    Brekken, J.2    Zou, H.3
  • 48
    • 0032905581 scopus 로고    scopus 로고
    • Marked inhibition of tumor growth in a malignant glioma tumor model by a novel synthetic matrix metalloproteinase inhibitor AG3340
    • Price A, Shi Q, Morris D, et al. Marked inhibition of tumor growth in a malignant glioma tumor model by a novel synthetic matrix metalloproteinase inhibitor AG3340. Clin Cancer Res 1999; 5: 845-54.
    • (1999) Clin Cancer Res , vol.5 , pp. 845-854
    • Price, A.1    Shi, Q.2    Morris, D.3
  • 49
    • 0002815897 scopus 로고    scopus 로고
    • A phase I study of AG3340, a matrix metalloprotease (MMP) inhibitor, in patients having advanced cancer
    • abstract
    • Hande K, Wilding G, Ripple G, et al. A phase I study of AG3340, a matrix metalloprotease (MMP) inhibitor, in patients having advanced cancer. Ann Oncol 1998; 9 (Suppl 2): 74 (abstract).
    • (1998) Ann Oncol , vol.9 , Issue.SUPPL. 2 , pp. 74
    • Hande, K.1    Wilding, G.2    Ripple, G.3
  • 50
    • 0002593621 scopus 로고    scopus 로고
    • CGS 27023A, a potent and orally active matrix metalloprotease inhibitor with antitumor activity
    • abstract
    • Wood JM, Muller M, Schnell C, et al. CGS 27023A, a potent and orally active matrix metalloprotease inhibitor with antitumor activity. Proc Am Ass Cancer Res 1998; 39: 83 (abstract).
    • (1998) Proc Am Ass Cancer Res , vol.39 , pp. 83
    • Wood, J.M.1    Muller, M.2    Schnell, C.3
  • 51
    • 0000436339 scopus 로고    scopus 로고
    • A phase one pharmacokinetic study of CGS27023A, a matrix metallo-proteinase inhibitor
    • abstract
    • Levitt NC, Eskens F, Propper DJ, et al. A phase one pharmacokinetic study of CGS27023A, a matrix metallo-proteinase inhibitor. Proc ASCO 1998; 17: 213a (abstract).
    • (1998) Proc ASCO , vol.17
    • Levitt, N.C.1    Eskens, F.2    Propper, D.J.3
  • 53
    • 0032548966 scopus 로고    scopus 로고
    • Serum matrix metalloproteinase-2 and its density in men with prostate cancer as a new predictor of disease extension
    • Gohji K, Fujimoto N, Hara I, et al. Serum matrix metalloproteinase-2 and its density in men with prostate cancer as a new predictor of disease extension. Int J Cancer 1998; 79: 96-101.
    • (1998) Int J Cancer , vol.79 , pp. 96-101
    • Gohji, K.1    Fujimoto, N.2    Hara, I.3
  • 54
    • 0032578698 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 in blood does not indicate the progression of prostate cancer
    • Jung K, Laube C, Lein M, et al. Matrix metalloproteinase-2 in blood does not indicate the progression of prostate cancer. Int J Cancer 1998; 78: 392-3.
    • (1998) Int J Cancer , vol.78 , pp. 392-393
    • Jung, K.1    Laube, C.2    Lein, M.3
  • 55
    • 0027388922 scopus 로고
    • M(r) 92,000 type IV collagenase is increased in plasma of patients with colon cancer and breast cancer
    • Zucker S, Lysik RM, Zarrabi M H, Moll U. M(r) 92,000 type IV collagenase is increased in plasma of patients with colon cancer and breast cancer. Cancer Res 1993; 53: 140-6.
    • (1993) Cancer Res , vol.53 , pp. 140-146
    • Zucker, S.1    Lysik, R.M.2    Zarrabi, M.H.3    Moll, U.4
  • 56
    • 0032926187 scopus 로고    scopus 로고
    • Elevated levels of circulating plasma matrix metalloproteinase 9 in non-small cell lung cancer patients
    • Iizasa T, Fujisawa T, Suzuki M, et al. Elevated levels of circulating plasma matrix metalloproteinase 9 in non-small cell lung cancer patients. Clin Cancer Res 1999; 5: 149-53.
    • (1999) Clin Cancer Res , vol.5 , pp. 149-153
    • Iizasa, T.1    Fujisawa, T.2    Suzuki, M.3
  • 58
    • 0032837901 scopus 로고    scopus 로고
    • MMP-9 activity in urine from patients with various tumors, as measured by a novel MMP activity assay using modified urokinase as a substrate
    • Hanemaaijer R, Sier CF, Visser H, et al. MMP-9 activity in urine from patients with various tumors, as measured by a novel MMP activity assay using modified urokinase as a substrate. Ann NY Acad Sci 1999; 878: 141-9.
    • (1999) Ann NY Acad Sci , vol.878 , pp. 141-149
    • Hanemaaijer, R.1    Sier, C.F.2    Visser, H.3
  • 59
    • 0027723123 scopus 로고
    • A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 2 (72-kDa gelatinase/type IV collagenase) using monoclonal antibodies
    • Fujimoto N, Mouri N, Iwata K, Ohuchi E, Okada Y, Hayakawa T. A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 2 (72-kDa gelatinase/type IV collagenase) using monoclonal antibodies. Clinica Chimica Acta 1993; 221: 91-103.
    • (1993) Clinica Chimica Acta , vol.221 , pp. 91-103
    • Fujimoto, N.1    Mouri, N.2    Iwata, K.3    Ohuchi, E.4    Okada, Y.5    Hayakawa, T.6
  • 60
    • 0026802371 scopus 로고
    • Correlation of serum metalloproteinase levels with lung cancer metastasis and response to therapy
    • Garbisa S, Scagliotti G, Masiero L, et al. Correlation of serum metalloproteinase levels with lung cancer metastasis and response to therapy. Cancer Res 1992; 52: 4548-9.
    • (1992) Cancer Res , vol.52 , pp. 4548-4549
    • Garbisa, S.1    Scagliotti, G.2    Masiero, L.3
  • 61
    • 0025001756 scopus 로고
    • Immunoassays for the detection of human collagenase, stromelysin, tissue inhibitor of metalloproteinases (TIMP) and enzyme-inhibitor complexes
    • Cooksley S, Hipkiss JB, Tickle SP, et al. Immunoassays for the detection of human collagenase, stromelysin, tissue inhibitor of metalloproteinases (TIMP) and enzyme-inhibitor complexes. Matrix 1990; 10: 285-91.
    • (1990) Matrix , vol.10 , pp. 285-291
    • Cooksley, S.1    Hipkiss, J.B.2    Tickle, S.P.3
  • 62
    • 0027050325 scopus 로고    scopus 로고
    • Monoclonal antibodies against human fibroblast collagenase and the design of an enzyme-linked immunosorbent assay to measure total collagenase
    • Clark IM, Powell LK, Wright JK, Cawston TE, Hazleman B. Monoclonal antibodies against human fibroblast collagenase and the design of an enzyme-linked immunosorbent assay to measure total collagenase. Matrix 1999; 12: 475-80.
    • (1999) Matrix , vol.12 , pp. 475-480
    • Clark, I.M.1    Powell, L.K.2    Wright, J.K.3    Cawston, T.E.4    Hazleman, B.5
  • 63
    • 0023746649 scopus 로고
    • Membrane and matrix localization of proteinases: A common theme in tumor cell invasion and angiogenesis
    • Moscatelli D, Rifkin DB. Membrane and matrix localization of proteinases: a common theme in tumor cell invasion and angiogenesis. Biochim Biophys Acta 1988; 948: 67-84.
    • (1988) Biochim Biophys Acta , vol.948 , pp. 67-84
    • Moscatelli, D.1    Rifkin, D.B.2
  • 64
    • 0032836427 scopus 로고    scopus 로고
    • Measurement of matrix metalloproteinases and tissue inhibitors of metalloproteinases in blood and tissues. Clinical and experimental applications
    • Zucker S, Hymowitz M, Conner C, et al. Measurement of matrix metalloproteinases and tissue inhibitors of metalloproteinases in blood and tissues. Clinical and experimental applications. Ann NY Acad Sci 1999; 878: 212-27.
    • (1999) Ann NY Acad Sci , vol.878 , pp. 212-227
    • Zucker, S.1    Hymowitz, M.2    Conner, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.