Network-based characterization of drug-regulated genes, drug targets, and toxicity

Methods

Volumn 57, Issue 4, 2012, Pages 499-507

  Kotlyar, Max ^a   Fortney, Kristen ^b   Jurisica, Igor ^a,b,c,d  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HEALTH NETWORK   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Drug cytotoxicity; Drug development; Protein protein interactions; Transcription regulation

Indexed keywords

IMATINIB; METFORMIN; NELFINAVIR; SILDENAFIL;

DNA BINDING; DRUG TARGETING; GENE EXPRESSION; GENOME; HUMAN; INSULIN RESISTANCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REVIEW;

CLUSTER ANALYSIS; COMPUTER SIMULATION; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION REGULATION; HUMANS; MODELS, BIOLOGICAL; PROTEIN INTERACTION MAPPING; PROTEIN INTERACTION MAPS; STATISTICS, NONPARAMETRIC;

EID: 84866384551     PISSN: 10462023     EISSN: 10959130     Source Type: Journal    
DOI: 10.1016/j.ymeth.2012.06.003     Document Type: Review

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