Structure of protein interaction networks and their implications on drug design

PLoS Computational Biology

Volumn 5, Issue 10, 2009, Pages

  Hase, Takeshi ^a   Tanaka, Hiroshi ^a   Suzuki, Yasuhiro ^b   Nakagawa, So ^c   Kitano, Hiroaki ^d,e,f  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF GENETICS   (Japan)

^d SONY COMPUTER SCIENCE LABORATORIES INC   (Japan)

^e The Systems Biology Institute   (Japan)

^f OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG INTERACTIONS; PROTEINS; TOPOLOGY;

BUDDING YEASTS; DRUG DESIGN; DRUG TARGETS; NETWORK PROPERTIES; PROTEIN INTERACTION NETWORKS; PROTEIN-PROTEIN INTERACTION NETWORKS; SOURCES OF INFORMATIONS; STATISTICAL PROPERTIES; TOPOLOGICAL PROPERTIES; YEAST PROTEINS;

GENES;

CELL PROTEIN; DASATINIB; FUNGAL PROTEIN; PROTEIN;

ARTICLE; BUDDING; DRUG DESIGN; DRUG TARGETING; GENE CONTROL; GENE REGULATORY NETWORK; NONHUMAN; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; YEAST; CHEMISTRY; CLUSTER ANALYSIS; DRUG DELIVERY SYSTEM; GENETICS; GENOMICS; HUMAN; METHODOLOGY; PHYSIOLOGY; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

SACCHAROMYCETALES;

CLUSTER ANALYSIS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; FUNGAL PROTEINS; GENOMICS; HUMANS; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEINS; SIGNAL TRANSDUCTION; YEASTS;

EID: 73549090972     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000550     Document Type: Article

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