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Volumn 22, Issue 6-7, 2008, Pages 367-384
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Utilizing high throughput screening data for predictive toxicology models: Protocols and application to MLSCN assays
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Author keywords
Animal toxicity; Cell proliferation; Domain applicability; HT Sassay; Jurkat cell line; QSAR
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Indexed keywords
ANIMALS;
CELL CULTURE;
CELL PROLIFERATION;
CLASSIFICATION (OF INFORMATION);
COMPUTATIONAL CHEMISTRY;
DECISION TREES;
LIBRARIES;
ANIMAL TOXICITY;
CELL LINES;
DOMAIN APPLICABILITY;
HT SASSAY;
JURKAT CELL;
JURKAT CELL LINE;
LIBRARY SCREENING;
MOLECULAR LIBRARIES;
QSAR;
SCREENING DATA;
TOXICITY;
ADENOSINE 5' (N ETHYLCARBOXAMIDE);
BREFELDIN A;
COLCHICINE;
DACTINOMYCIN;
DAUNORUBICIN;
DIGOXIN;
DOXORUBICIN;
EMETINE;
MALACHITE GREEN;
MEBENDAZOLE;
NEOSTIGMINE;
PANCURONIUM;
PARATHION;
PHENYLMERCURIC ACETATE;
PHYSOSTIGMINE;
PODOPHYLLOTOXIN;
PYRIDOSTIGMINE;
PYRITHIONE ZINC;
RESERPINE;
VINBLASTINE;
VINCRISTINE;
ACCURACY;
ANIMAL CELL;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTINEOPLASTIC ACTIVITY;
CARDIOTOXICITY;
CELL PROLIFERATION;
CELL VIABILITY;
CLASSIFICATION;
CONFERENCE PAPER;
CONTROLLED STUDY;
CYTOTOXICITY;
DATA BASE;
DIARRHEA;
DRUG STRUCTURE;
HIGH THROUGHPUT SCREENING;
HUMAN;
HUMAN CELL;
LIVER TOXICITY;
MATHEMATICAL ANALYSIS;
MATHEMATICAL MODEL;
METABOLIC DISORDER;
MOLECULAR LIBRARY;
MOUSE;
NEPHROTOXICITY;
NONHUMAN;
PREDICTION;
PRIORITY JOURNAL;
QUANTITATIVE STRUCTURE ACTIVITY RELATION;
RAT;
RELIABILITY;
STRUCTURE ANALYSIS;
TOXICITY TESTING;
TOXICOLOGY;
VOMITING;
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EID: 44249108095
PISSN: 0920654X
EISSN: 15734951
Source Type: Journal
DOI: 10.1007/s10822-008-9192-9 Document Type: Conference Paper |
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Times cited : (45)
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References (49)
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