The NMDA receptor as a target for cognitive enhancement

Neuropharmacology

Volumn 64, Issue , 2013, Pages 13-26

  Collingridge, Graham L ^a,b   Volianskis, Arturas ^a   Bannister, Neil ^a   France, Grace ^a   Hanna, Lydia ^a   Mercier, Marion ^a   Tidball, Patrick ^a   Fang, Guangyu ^a   Irvine, Mark W ^a   Costa, Blaise M ^c   Monaghan, Daniel T ^c   Bortolotto, Zuner A ^a   Molnár, Elek ^a   Lodge, David ^a   Jane, David E ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b Seoul National University   (South Korea)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Cognitive enhancement; Hippocampus; LTP; NMDA receptor; Positive allosteric modulators; Synaptic plasticity; Synaptic transmission

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 3,5 DIHYDROXYNAPHTHALENE 2 CARBOXYLIC ACID; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID RECEPTOR; 6 BROMO 4 METHYLCOUMARIN 3 CARBOXYLIC ACID; 6 BROMOCOUMARIN 3 CARBOXYLIC ACID; [(3 CHLOROPHENYL)(6,7 DIMETHOXY 1)[(4 METHOXYPHENOXY)METHYL] 3,4 DIHYDROISOQUINOLIN 2(1H) YL]METHANONE; ADENOSINE TRIPHOSPHATE; AMPA RECEPTOR; ANIRACETAM; BITOPERTIN; CALPAIN; CHOLINERGIC RECEPTOR; COUMARIN DERIVATIVE; DEXTRO SERINE; ELTANOLONE; GLYCINE; HISTAMINE; ISOQUINOLINE DERIVATIVE; MEMANTINE; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NAPHTHALENE DERIVATIVE; NEUROSTEROID; PHENANTHRENE DERIVATIVE; POLYAMINE; PREGNENOLONE SULFATE; UBP 512; UBP 551; UBP 710; UBP 714; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALZHEIMER DISEASE; AMNESIA; COGNITION; DRUG MECHANISM; DRUG STRUCTURE; HUMAN; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; REVIEW; SCHIZOPHRENIA; SYNAPTIC TRANSMISSION; UBIQUITINATION;

ANIMALS; COGNITION; COGNITION DISORDERS; HIPPOCAMPUS; HUMANS; MOLECULAR TARGETED THERAPY; NERVE TISSUE PROTEINS; NEURONS; NOOTROPIC AGENTS; PERFORMANCE-ENHANCING SUBSTANCES; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTIC TRANSMISSION;

EID: 84866370557     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.06.051     Document Type: Review

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