Control of NMDA receptor activation by a glycine transporter co- expressed in Xenopus oocytes

Journal of Neuroscience

Volumn 17, Issue 12, 1997, Pages 4580-4590

  Supplisson, Stephane ^a   Bergman, Claude ^a  

^a ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

Coagonist; D serine; Glutamate receptor; NMDA; Sarcosine; Synaptic cleft

Indexed keywords

CARRIER PROTEIN; COMPLEMENTARY DNA; GLUTAMIC ACID; GLYCINE; LITHIUM ION; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBUNIT; SODIUM ION;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; FEMALE; HYPERPOLARIZATION; MEMBRANE POTENTIAL; MEMBRANE TRANSPORT; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNAPTIC TRANSMISSION; VOLTAGE CLAMP; XENOPUS LAEVIS;

EID: 0030919910     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-12-04580.1997     Document Type: Article

References (17)

1. Adams RH, Sato K, Shimada S, Tohyama M, Püschel AW, Betz H (1995) Gene structure and glial expression of the glycine transporter GLYT1 in embryonic and adult rodents. J Neurosci 15:2524-2532.
2. Ascher P (1990) Measuring and controlling the extracellular glycine concentration at the NMDA receptor level. Exp Med Biol Adv 268:13-16.
3. Attwell D, Bouvier M (1992) Cloners quick on the uptake. Curr Biol 2:541-543.
4. Attwell D, Barbour B, Szatkowski M (1993) Nonvesicular release of neurotransmitter. Neuron 11:401-407.
5. Barbour B, Keller BU, Llano I, Marty A (1994) Prolonged presence of glutamate during excitatory synaptic transmission to cerebellar Purkinje cells. Neuron 12:1331-1343.
6. Barry PH, Diamond JM (1984) Effects of unstirred layers on membrane phenomena. Physiol Rev 64:763-872.
7. Benveniste M, Clements J, Vyklický LJ, Mayer ML (1990) A kinetic analysis of the modulation of N-methyl-D-aspartic acid receptors by glycine in mouse cultured hippocampal neurones. J Physiol (Lond) 428:333-357.
8. Brew H, Attwell D (1987) Electrogenic glutamate uptake is a major current carrier in the membrane of axolotl retinal glial cells. Nature 327:707-709.
9. Costa ACS, Patrick J, Dani JA (1994) Improved technique for studying ion channels expressed in Xenopits oocytes, including fast superfusion. Biophys J 67:395-401.
10. D'angelo E, Rossi P, Garthwaite J (1990) Dual-component NMDA receptor currents at a single central synapse. Nature 346:467-470.
11. 3H]glycine uptake in rat hippocampus: kinetic analysis and autoradiographic localization. Brain Res 572:154-163.
12. Guastclla J, Brecha N, Weigmann C, Lester HA, Davidson N (1992) Cloning, expression, and localization of a rat brain high-affinity glycine transporter. Proc Natl Acad Sci USA 89:7189-7193.
13. Johnson JW, Ascher P (1987) Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 325:529-531.
14. Kemp JA, Leeson PD (1993) The glycine site of the NMDA receptor - five years on. Trends Pharmacol Sci 14:20-25.
15. Supplisson S, Neyton J, Paoletti P, Bergman C, Ascher P, Teichberg V (1994) Modulation of NMDA-induced currents by a glycine transporter coexpressed with a NMDA receptor in Xenopus oocyte. Soc Neurosci Abstr 20:919.
16. Thiels E, Weisz DJ, Berger TW (1992) In vivo modulation of N-methyl-D-aspartate receptor-dependent long-term potentiation by the glycine modulatory site. Neuroscience 46:501-509.
17. Thomson AM (1990) Glycine is a coagonist at the NMDA receptor/channel complex. Prog Neurobiol 35:53-74.