메뉴 건너뛰기




Volumn 4, Issue SPEC. ISSUE 1, 2010, Pages 3-9

The therapeutic potential of D-amino acid oxidase (DAAO) inhibitors

Author keywords

D serine. D amino acid oxidase; NMDA receptor; Schizophrenia

Indexed keywords

3 HYDROXYQUINOLIN 2(1H) ONE; 5 METHYL 3 PYRAZOLECARBOXYLIC ACID; ASO 57278; ATYPICAL ANTIPSYCHOTIC AGENT; BENZOIC ACID; CBIO; DEXTRO ALANINE; DEXTRO AMINO ACID OXIDASE; DEXTRO SERINE; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OXIDOREDUCTASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 78249248949     PISSN: None     EISSN: 18741045     Source Type: Journal    
DOI: 10.2174/1874104501004020003     Document Type: Article
Times cited : (78)

References (55)
  • 1
    • 0001062020 scopus 로고
    • Metabolism of amino-acids: Deamination of amino-acids
    • Krebs, H. A. Metabolism of amino-acids: deamination of amino-acids. Biochem. J., 1935, 29, 1620-1644.
    • (1935) Biochem. J , vol.29 , pp. 1620-1644
    • Krebs, H.A.1
  • 2
    • 0035019761 scopus 로고    scopus 로고
    • Assignment of D-amino-acid oxidase gene to a human and a mouse chromosome
    • Konno, R. Assignment of D-amino-acid oxidase gene to a human and a mouse chromosome. Amino Acids, 2001, 20, 401-408.
    • (2001) Amino Acids , vol.20 , pp. 401-408
    • Konno, R.1
  • 3
    • 14844283777 scopus 로고    scopus 로고
    • D-Amino acid oxidase: Structure, catalytic mechanism, and practical application
    • Tishkov, V. I.; Khoronenkova, S. V. D-Amino acid oxidase: structure, catalytic mechanism, and practical application. Biochemistry (Mosc), 2005, 70, 40-54.
    • (2005) Biochemistry (Mosc) , vol.70 , pp. 40-54
    • Tishkov, V.I.1    Khoronenkova, S.V.2
  • 4
    • 0033679728 scopus 로고    scopus 로고
    • D-Amino acid oxidase: New findings
    • Pilone, M. S. D-Amino acid oxidase: new findings. Cell Mol. Life Sci., 2000, 57, 1732-1747.
    • (2000) Cell Mol. Life Sci , vol.57 , pp. 1732-1747
    • Pilone, M.S.1
  • 5
    • 0037189929 scopus 로고    scopus 로고
    • Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach
    • Piubelli, L.; Caldinelli, L.; Molla, G.; Pilone, M. S.; Pollegioni, L. Conversion of the dimeric D-amino acid oxidase from Rhodotorula gracilis to a monomeric form. A rational mutagenesis approach. FEBS Lett., 2002, 526, 43-48.
    • (2002) FEBS Lett , vol.526 , pp. 43-48
    • Piubelli, L.1    Caldinelli, L.2    Molla, G.3    Pilone, M.S.4    Pollegioni, L.5
  • 7
    • 0023681465 scopus 로고
    • Molecular cloning and sequence analysis of cDNA encoding human kidney D-amino acid oxidase
    • Momoi, K.; Fukui, K.; Watanabe, F.; Miyake, Y. Molecular cloning and sequence analysis of cDNA encoding human kidney D-amino acid oxidase. FEBS Lett., 1988, 238, 180-184.
    • (1988) FEBS Lett , vol.238 , pp. 180-184
    • Momoi, K.1    Fukui, K.2    Watanabe, F.3    Miyake, Y.4
  • 8
    • 0025858956 scopus 로고
    • Immunochemical relationship of D-amino acid oxidases in various tissues and animals
    • Katagiri, M.; Tojo, H.; Horiike, K.; Yamano, T. Immunochemical relationship of D-amino acid oxidases in various tissues and animals. Comp. Biochem. Physiol. B, 1991, 99, 345-350.
    • (1991) Comp. Biochem. Physiol. B , vol.99 , pp. 345-350
    • Katagiri, M.1    Tojo, H.2    Horiike, K.3    Yamano, T.4
  • 9
    • 0028176862 scopus 로고
    • D-amino-acid oxidase is confined to the lower brain stem and cerebellum in rat brain: Regional differentiation of astrocytes
    • Horiike, K.; Tojo, H.; Arai, R.; Nozaki, M.; Maeda, T. D-amino-acid oxidase is confined to the lower brain stem and cerebellum in rat brain: regional differentiation of astrocytes. Brain Res., 1994, 652, 297-303.
    • (1994) Brain Res , vol.652 , pp. 297-303
    • Horiike, K.1    Tojo, H.2    Arai, R.3    Nozaki, M.4    Maeda, T.5
  • 10
    • 34548689595 scopus 로고    scopus 로고
    • W. d-Amino acid oxidase and serine racemase in human brain: Normal distribution and altered expression in schizophrenia
    • Verrall, L.; Walker, M.; Rawlings, N.; Benzel, I.; Kew, J. N.; Harrison, P. J.; Burnet, P. W. d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia. Eur. J. Neurosci., 2007, 26, 1657-1669.
    • (2007) Eur. J. Neurosci , vol.26 , pp. 1657-1669
    • Verrall, L.1    Walker, M.2    Rawlings, N.3    Benzel, I.4    Kew, J.N.5    Harrison, P.J.6    Burnet, P.7
  • 12
    • 0032581422 scopus 로고    scopus 로고
    • D-aspartate uptake into cultured rat pinealocytes and the concomitant effect on L-aspartate levels and melatonin secretion
    • Takigawa, Y.; Homma, H.; Lee, J. A.; Fukushima, T.; Santa, T.; Iwatsubo, T.; Imai, K. D-aspartate uptake into cultured rat pinealocytes and the concomitant effect on L-aspartate levels and melatonin secretion. Biochem. Biophys. Res. Commun., 1998, 248, 641-647.
    • (1998) Biochem. Biophys. Res. Commun , vol.248 , pp. 641-647
    • Takigawa, Y.1    Homma, H.2    Lee, J.A.3    Fukushima, T.4    Santa, T.5    Iwatsubo, T.6    Imai, K.7
  • 13
    • 0033735457 scopus 로고    scopus 로고
    • The role of D-aspartic acid and N-methyl-D-aspartic acid in the regulation of prolactin release
    • D'Aniello, G.; Tolino, A.; D'Aniello, A.; Errico, F.; Fisher, G. H.; Di Fiore, M. M. The role of D-aspartic acid and N-methyl-D-aspartic acid in the regulation of prolactin release. Endocrinology, 2000, 141, 3862-70.
    • (2000) Endocrinology , vol.141 , pp. 3862-3870
    • D'aniello, G.1    Tolino, A.2    D'aniello, A.3    Errico, F.4    Fisher, G.H.5    Di Fiore, M.M.6
  • 14
    • 0031770236 scopus 로고    scopus 로고
    • A, D. A. Free D- and L-amino acids in ventricular cerebrospinal fluid from Alzheimer and normal subjects
    • Fisher, G.; Lorenzo, N.; Abe, H.; Fujita, E.; Frey, W. H.; Emory, C.; Di Fiore, M. M.; A, D. A. Free D- and L-amino acids in ventricular cerebrospinal fluid from Alzheimer and normal subjects. Amino Acids, 1998, 15, 263-269.
    • (1998) Amino Acids , vol.15 , pp. 263-269
    • Fisher, G.1    Lorenzo, N.2    Abe, H.3    Fujita, E.4    Frey, W.H.5    Emory, C.6    Di Fiore, M.M.7
  • 15
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurons
    • Johnson, J. W.; Ascher, P. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature, 1987, 325, 529-531.
    • (1987) Nature , vol.325 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 16
    • 0027469106 scopus 로고
    • The glycine site of the NMDA receptor- -five years on. Trends Pharmacol
    • Kemp, J. A.; Leeson, P. D. The glycine site of the NMDA receptor- -five years on. Trends Pharmacol. Sci., 1993, 14, 20-25.
    • (1993) Sci , vol.14 , pp. 20-25
    • Kemp, J.A.1    Leeson, P.D.2
  • 18
    • 0035805393 scopus 로고    scopus 로고
    • Effect of the glycine modulatory site of the N- methyl-D-aspartate receptor on synaptic responses in kitten visual cortex
    • Ito, K.; Hicks, T. P. Effect of the glycine modulatory site of the N- methyl-D-aspartate receptor on synaptic responses in kitten visual cortex. Neurosci. Lett., 2001, 303, 95-98.
    • (2001) Neurosci. Lett , vol.303 , pp. 95-98
    • Ito, K.1    Hicks, T.P.2
  • 19
    • 26844461474 scopus 로고    scopus 로고
    • D-serine is the dominant endogenous coagonist for NMDA receptor neurotoxicity in organotypic hippocampal slices
    • Shleper, M.; Kartvelishvily, E.; Wolosker, H. D-serine is the dominant endogenous coagonist for NMDA receptor neurotoxicity in organotypic hippocampal slices. J. Neurosci., 2005, 25, 9413-9417.
    • (2005) J. Neurosci , vol.25 , pp. 9413-9417
    • Shleper, M.1    Kartvelishvily, E.2    Wolosker, H.3
  • 22
    • 0023082787 scopus 로고
    • Negative schizophrenic symptomatology and the PCP (phencyclidine) model of schizophrenia
    • Javitt, D. C. Negative schizophrenic symptomatology and the PCP (phencyclidine) model of schizophrenia. Hillside J. Clin. Psychiatry, 1987, 9, 12-35.
    • (1987) Hillside J. Clin. Psychiatry , vol.9 , pp. 12-35
    • Javitt, D.C.1
  • 26
    • 21244502642 scopus 로고    scopus 로고
    • Reduced D-serine to Total Serine Ratio In the Cerebrospinal Fluid of Drug Naive Schizophrenic Patients
    • Hashimoto, K.; Engberg, G.; Shimizu, E.; Nordin, C.; Lindstrom, L. H.; Iyo, M. Reduced D-serine to total serine ratio in the cerebrospinal fluid of drug naive schizophrenic patients. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2005, 29, 767-769.
    • (2005) Prog. Neuropsychopharmacol. Biol , vol.29 , pp. 767-769
    • Hashimoto, K.1    Engberg, G.2    Shimizu, E.3    Nordin, C.4    Lindstrom, L.H.5    Iyo, M.6
  • 29
    • 0029658545 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled, crossover trial of glycine adjuvant therapy for treatment-resistant schizophrenia
    • Heresco-Levy, U.; Javitt, D. C.; Ermilov, M.; Mordel, C.; Horowitz, A.; Kelly, D. Double-blind, placebo-controlled, crossover trial of glycine adjuvant therapy for treatment-resistant schizophrenia. Br. J. Psychiatry, 1996, 169, 610-617.
    • (1996) Br. J. Psychiatry , vol.169 , pp. 610-617
    • Heresco-Levy, U.1    Javitt, D.C.2    Ermilov, M.3    Mordel, C.4    Horowitz, A.5    Kelly, D.6
  • 31
    • 0036184549 scopus 로고    scopus 로고
    • Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia
    • Heresco-Levy, U.; Ermilov, M.; Shimoni, J.; Shapira, B.; Silipo, G.; Javitt, D. C. Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia. Am. J. Psychiatry, 2002, 159, 480-482.
    • (2002) Am. J. Psychiatry , vol.159 , pp. 480-482
    • Heresco-Levy, U.1    Ermilov, M.2    Shimoni, J.3    Shapira, B.4    Silipo, G.5    Javitt, D.C.6
  • 32
    • 0032403626 scopus 로고    scopus 로고
    • D-serine added to antipsychotics for the treatment of schizophrenia
    • Tsai, G.; Yang, P.; Chung, L. C.; Lange, N.; Coyle, J. T. D-serine added to antipsychotics for the treatment of schizophrenia. Biol. Psychiatry, 1998, 44, 1081-1089.
    • (1998) Biol. Psychiatry , vol.44 , pp. 1081-1089
    • Tsai, G.1    Yang, P.2    Chung, L.C.3    Lange, N.4    Coyle, J.T.5
  • 35
    • 0027159584 scopus 로고
    • Free D-serine, D-aspartate and D- alanine in central nervous system and serum in mutant mice lacking D-amino acid oxidase
    • Hashimoto, A.; Nishikawa, T.; Konno, R.; Niwa, A.; Yasumura, Y.; Oka, T.; Takahashi, K. Free D-serine, D-aspartate and D- alanine in central nervous system and serum in mutant mice lacking D-amino acid oxidase. Neurosci. Lett., 1993, 152, 33-36.
    • (1993) Neurosci. Lett , vol.152 , pp. 33-36
    • Hashimoto, A.1    Nishikawa, T.2    Konno, R.3    Niwa, A.4    Yasumura, Y.5    Oka, T.6    Takahashi, K.7
  • 36
    • 23044465220 scopus 로고    scopus 로고
    • Spatial learning and long-term potentiation of mutant mice lacking D-amino-acid oxidase
    • Maekawa, M.; Watanabe, M.; Yamaguchi, S.; Konno, R.; Hori, Y. Spatial learning and long-term potentiation of mutant mice lacking D-amino-acid oxidase. Neurosci. Res., 2005, 53, 34-38.
    • (2005) Neurosci. Res , vol.53 , pp. 34-38
    • Maekawa, M.1    Watanabe, M.2    Yamaguchi, S.3    Konno, R.4    Hori, Y.5
  • 37
    • 0035808617 scopus 로고    scopus 로고
    • Exaggerated responses to chronic nociceptive stimuli and enhancement of N-methyl-D-aspartate receptor- mediated synaptic transmission in mutant mice lacking D-amino- acid oxidase
    • Wake, K.; Yamazaki, H.; Hanzawa, S.; Konno, R.; Sakio, H.; Niwa, A.; Hori, Y. Exaggerated responses to chronic nociceptive stimuli and enhancement of N-methyl-D-aspartate receptor- mediated synaptic transmission in mutant mice lacking D-amino- acid oxidase. Neurosci. Lett., 2001, 297, 25-28.
    • (2001) Neurosci. Lett , vol.297 , pp. 25-28
    • Wake, K.1    Yamazaki, H.2    Hanzawa, S.3    Konno, R.4    Sakio, H.5    Niwa, A.6    Hori, Y.7
  • 44
    • 67349116852 scopus 로고    scopus 로고
    • Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine
    • Hashimoto, K.; Fujita, Y.; Horio, M.; Kunitachi, S.; Iyo, M.; Ferraris, D.; Tsukamoto, T. Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine. Biol. Psychiatry, 2009, 65, 1103-1106.
    • (2009) Biol. Psychiatry , vol.65 , pp. 1103-1106
    • Hashimoto, K.1    Fujita, Y.2    Horio, M.3    Kunitachi, S.4    Iyo, M.5    Ferraris, D.6    Tsukamoto, T.7
  • 45
    • 0025228762 scopus 로고
    • D-serine antagonized phencyclidine- and MK-801- induced stereotyped behavior and ataxia
    • Contreras, P. C. D-serine antagonized phencyclidine- and MK-801- induced stereotyped behavior and ataxia. Neuropharmacology, 1990, 29, 291-293.
    • (1990) Neuropharmacology , vol.29 , pp. 291-293
    • Contreras, P.C.1
  • 46
    • 17744372866 scopus 로고    scopus 로고
    • Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia
    • Lipina, T.; Labrie, V.; Weiner, I.; Roder, J. Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia. Psychopharmacology (Berl), 2005, 179, 54-67.
    • (2005) Psychopharmacology (Berl) , vol.179 , pp. 54-67
    • Lipina, T.1    Labrie, V.2    Weiner, I.3    Roder, J.4
  • 47
    • 42749085595 scopus 로고    scopus 로고
    • Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the glycine transporter-1 inhibitor NFPS and D-serine
    • Hashimoto, K.; Fujita, Y.; Ishima, T.; Chaki, S.; Iyo, M. Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the glycine transporter-1 inhibitor NFPS and D-serine. Eur. Neuropsychopharmacol., 2008, 18, 414-421.
    • (2008) Eur. Neuropsychopharmacol , vol.18 , pp. 414-421
    • Hashimoto, K.1    Fujita, Y.2    Ishima, T.3    Chaki, S.4    Iyo, M.5
  • 48
    • 36049021794 scopus 로고    scopus 로고
    • D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats
    • Karasawa, J.; Hashimoto, K.; Chaki, S. D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats. Behav. Brain Res., 2008, 186, 78-83.
    • (2008) Behav. Brain Res , vol.186 , pp. 78-83
    • Karasawa, J.1    Hashimoto, K.2    Chaki, S.3
  • 50
    • 34249073110 scopus 로고    scopus 로고
    • Activation of supraspinal NMDA receptors by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail-flick test of rats
    • Yoshikawa, M.; Ito, K.; Maeda, M.; Akahori, K.; Takahashi, S.; Jin, X. L.; Matsuda, M.; Suzuki, T.; Oka, T.; Kobayashi, H.; Hashimoto, A. Activation of supraspinal NMDA receptors by both D-serine alone or in combination with morphine leads to the potentiation of antinociception in tail-flick test of rats. Eur. J. Pharmacol., 2007, 565, 89-97.
    • (2007) Eur. J. Pharmacol , vol.565 , pp. 89-97
    • Yoshikawa, M.1    Ito, K.2    Maeda, M.3    Akahori, K.4    Takahashi, S.5    Jin, X.L.6    Matsuda, M.7    Suzuki, T.8    Oka, T.9    Kobayashi, H.10    Hashimoto, A.11
  • 52
    • 0028172044 scopus 로고
    • N-methyl-D-aspartate receptor-mediated changes in thermal nociception: Allosteric modulation at glycine and polyamine recognition sites
    • Kolhekar, R.; Meller, S. T.; Gebhart, G. F. N-methyl-D-aspartate receptor-mediated changes in thermal nociception: allosteric modulation at glycine and polyamine recognition sites. Neuroscience, 1994, 63, 925-936.
    • (1994) Neuroscience , vol.63 , pp. 925-936
    • Kolhekar, R.1    Meller, S.T.2    Gebhart, G.F.3
  • 53
    • 0035840856 scopus 로고    scopus 로고
    • NMDA receptors as targets for drug action in neuropathic pain
    • Parsons, C. G. NMDA receptors as targets for drug action in neuropathic pain. Eur. J. Pharmacol., 2001, 429, 71-78.
    • (2001) Eur. J. Pharmacol , vol.429 , pp. 71-78
    • Parsons, C.G.1
  • 54
    • 33644825886 scopus 로고    scopus 로고
    • Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect
    • Ren, W. H.; Guo, J. D.; Cao, H.; Wang, H.; Wang, P. F.; Sha, H.; Ji, R. R.; Zhao, Z. Q.; Zhang, Y. Q. Is endogenous D-serine in the rostral anterior cingulate cortex necessary for pain-related negative affect? J. Neurochem., 2006, 96, 1636-1647.
    • (2006) J. Neurochem , vol.96 , pp. 1636-1647
    • Ren, W.H.1    Guo, J.D.2    Cao, H.3    Wang, H.4    Wang, P.F.5    Sha, H.6    Ji, R.R.7    Zhao, Z.Q.8    Zhang, Y.Q.9
  • 55
    • 43049144983 scopus 로고    scopus 로고
    • Inhibition of D-amino-Acid oxidase activity induces pain relief in mice
    • Zhao, W.; Konno, R.; Zhou, X. J.; Yin, M.; Wang, Y. X. Inhibition of D-amino-Acid oxidase activity induces pain relief in mice. Cell Mol. Neurobiol., 2008, 28, 581-591.
    • (2008) Cell Mol. Neurobiol , vol.28 , pp. 581-591
    • Zhao, W.1    Konno, R.2    Zhou, X.J.3    Yin, M.4    Wang, Y.X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.