Autoantigen recognition is required for recruitment of IGRP 206-214-autoreactive CD8+ T cells but is dispensable for tolerance

Journal of Immunology

Volumn 189, Issue 6, 2012, Pages 2975-2984

  Wang, Jinguo ^a   Tsai, Sue ^a   Han, Bingye ^a   Tailor, Pankaj ^a   Santamaria, Pere ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CD3 ANTIGEN; CD3 EPSILON ANTIGEN; ISLET SPECIFIC GLUCOSE 6 PHOSPHATASE CATALYTIC RELATED PROTEIN[206-214]; MAJOR HISTOCOMPATIBILITY ANTIGEN; NCK PROTEIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RECOGNITION; ARTICLE; CD8+ T LYMPHOCYTE; COMPLEMENTARITY DETERMINING REGION; DEVELOPMENTAL BIOLOGY; DIABETES MELLITUS; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PANCREAS; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; T LYMPHOCYTE ACTIVATION;

AGING; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; AUTOANTIGENS; CATALYTIC DOMAIN; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CELL MOVEMENT; GENE SILENCING; GLUCOSE-6-PHOSPHATASE; IMMUNE TOLERANCE; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PROTEINS;

EID: 84866182947     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201787     Document Type: Article

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