메뉴 건너뛰기




Volumn 186, Issue 10, 1997, Pages 1663-1676

Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; MONOCLONAL ANTIBODY; RECOMBINANT INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 0030724897     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.186.10.1663     Document Type: Article
Times cited : (314)

References (51)
  • 1
    • 0028603590 scopus 로고
    • Genetic and pathogenic basis of autoimmune diabetes in NOD mice
    • Serreze, D.V., and E.H. Leiter. 1994. Genetic and pathogenic basis of autoimmune diabetes in NOD mice. Curr. Opin. Immunol. 6:900-906.
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 900-906
    • Serreze, D.V.1    Leiter, E.H.2
  • 2
    • 0029954214 scopus 로고    scopus 로고
    • Insulin-dependent diabetes mellitus
    • Tisch, R., and H.O. McDevitt. 1996. Insulin-dependent diabetes mellitus. Cell. 85:291-297.
    • (1996) Cell , vol.85 , pp. 291-297
    • Tisch, R.1    McDevitt, H.O.2
  • 4
    • 0023905731 scopus 로고
    • + T cell subsets are required for the transfer of diabetes in non-obese diabetic mice
    • + T cell subsets are required for the transfer of diabetes in non-obese diabetic mice. J. Immunol. 140:52-58.
    • (1988) J. Immunol. , vol.140 , pp. 52-58
    • Miller, B.J.1    Appel, M.C.2    O'Neil, J.J.3    Wicker, L.S.4
  • 5
    • 0026715030 scopus 로고
    • Analysis of the roles of CD4+ and CD8+ T cells in autoimmune diabetes of NOD mice using transfer to NOD athymic nude mice
    • Yagi, H., M. Matsumoto, K. Kunimoto, J. Kawaguchi, S. Makino, and M. Harada. 1992. Analysis of the roles of CD4+ and CD8+ T cells in autoimmune diabetes of NOD mice using transfer to NOD athymic nude mice. Eur. J. Immunol. 22:2387-2393.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2387-2393
    • Yagi, H.1    Matsumoto, M.2    Kunimoto, K.3    Kawaguchi, J.4    Makino, S.5    Harada, M.6
  • 6
    • 0027468997 scopus 로고
    • Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-thy-1a donors
    • Christianson, S.W., L.D. Shultz, and E.H. Leiter. 1993. Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-thy-1a donors. Diabetes. 42:44-55.
    • (1993) Diabetes , vol.42 , pp. 44-55
    • Christianson, S.W.1    Shultz, L.D.2    Leiter, E.H.3
  • 7
    • 0024947844 scopus 로고
    • An explanation for the protective effect of the MHC class II I-E molecule in murine diabetes
    • Reich, E.P., R.S. Sherwin, O. Kanagawa, and C.A. Janeway, Jr. 1989. An explanation for the protective effect of the MHC class II I-E molecule in murine diabetes. Nature (Lond.). 341:326-328.
    • (1989) Nature (Lond.) , vol.341 , pp. 326-328
    • Reich, E.P.1    Sherwin, R.S.2    Kanagawa, O.3    Janeway Jr., C.A.4
  • 8
    • 0025009870 scopus 로고
    • Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone
    • Haskins, K., and M. McDuffie. 1990. Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone. Science (Wash. DC). 249:1433-1436.
    • (1990) Science (Wash. DC) , vol.249 , pp. 1433-1436
    • Haskins, K.1    McDuffie, M.2
  • 9
    • 0025731505 scopus 로고
    • T cell receptor V gene usage of islet beta cell-reactive T cells is not restricted in non-obese diabetic mice
    • Nakano, N., H. Kikutani, H. Nishimoto, and T. Kishimoto. 1991. T cell receptor V gene usage of islet beta cell-reactive T cells is not restricted in non-obese diabetic mice. J. Exp. Med. 173:1091-1097.
    • (1991) J. Exp. Med. , vol.173 , pp. 1091-1097
    • Nakano, N.1    Kikutani, H.2    Nishimoto, H.3    Kishimoto, T.4
  • 10
    • 0026539665 scopus 로고
    • CD8+ T cells are not required for islet destruction induced by a CD4+ islet-specific T-cell clone
    • Bradley, B.J., K. Haskins, F.G. LaRosa, and K. Lafferty. 1992. CD8+ T cells are not required for islet destruction induced by a CD4+ islet-specific T-cell clone. Diabetes. 41: 1603-1608.
    • (1992) Diabetes , vol.41 , pp. 1603-1608
    • Bradley, B.J.1    Haskins, K.2    Larosa, F.G.3    Lafferty, K.4
  • 11
    • 0028914351 scopus 로고
    • Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from the NOD mouse
    • Daniel, D., R.G. Gill, N. Schloot, and D. Wegmann. 1994. Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from the NOD mouse. Eur. J. Immunol. 25:1056-1062.
    • (1994) Eur. J. Immunol. , vol.25 , pp. 1056-1062
    • Daniel, D.1    Gill, R.G.2    Schloot, N.3    Wegmann, D.4
  • 12
    • 0029030964 scopus 로고
    • T helper cell subsets in insulin dependent diabetes
    • Katz, J.D., C. Benoist, and D. Mathis. 1995. T helper cell subsets in insulin dependent diabetes. Science (Wash. DC). 268:1185-1188.
    • (1995) Science (Wash. DC) , vol.268 , pp. 1185-1188
    • Katz, J.D.1    Benoist, C.2    Mathis, D.3
  • 13
    • 0030022742 scopus 로고    scopus 로고
    • Transfer of diabetes in the NOD-scid mouse by CD4 T cell clones. Differential requirements for CD8 T cells
    • Peterson, J.D., and K. Haskins. 1996. Transfer of diabetes in the NOD-scid mouse by CD4 T cell clones. Differential requirements for CD8 T cells. Diabetes. 45:328-336.
    • (1996) Diabetes , vol.45 , pp. 328-336
    • Peterson, J.D.1    Haskins, K.2
  • 14
    • 0024312829 scopus 로고
    • The natural history of lymphocyte subsets infiltrating the pancreas of NOD mice
    • Signore, A., P. Pozzilli, E.A.M. Gale, D. Andreani, and P.C.L. Beverley. 1989. The natural history of lymphocyte subsets infiltrating the pancreas of NOD mice. Diabetologia. 32: 282-289.
    • (1989) Diabetologia , vol.32 , pp. 282-289
    • Signore, A.1    Pozzilli, P.2    Gale, E.A.M.3    Andreani, D.4    Beverley, P.C.L.5
  • 15
    • 0025858677 scopus 로고
    • Exclusive expression of MHC class II proteins on CD45+ cells in pancreatic islets of NOD mice
    • McInerney, M.F., S. Rath, and C.A. Janeway, Jr. 1991. Exclusive expression of MHC class II proteins on CD45+ cells in pancreatic islets of NOD mice. Diabetes. 40:648-651.
    • (1991) Diabetes , vol.40 , pp. 648-651
    • McInerney, M.F.1    Rath, S.2    Janeway Jr., C.A.3
  • 16
    • 13344294394 scopus 로고    scopus 로고
    • CD8 T cell clones from young NOD islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 T cells
    • Wong, F.S., I. Visintin, L. Wen, R.A. Flavell, and C.A. Janeway, Jr. 1996. CD8 T cell clones from young NOD islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 T cells. J. Exp. Med. 183:67-76.
    • (1996) J. Exp. Med. , vol.183 , pp. 67-76
    • Wong, F.S.1    Visintin, I.2    Wen, L.3    Flavell, R.A.4    Janeway Jr., C.A.5
  • 17
    • 0027367830 scopus 로고
    • Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice
    • Katz, J., C. Benoist, and D. Mathis. 1993. Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice. Eur. J. Immunol. 23:3358-3360.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3358-3360
    • Katz, J.1    Benoist, C.2    Mathis, D.3
  • 20
    • 0029841157 scopus 로고    scopus 로고
    • The role of CD8+ T cells in initiation of insulin-dependent diabetes mellitus
    • Wang, B., A. Gonzalez, C. Benoist, and D. Mathis. 1996. The role of CD8+ T cells in initiation of insulin-dependent diabetes mellitus. Eur. J. Immunol. 26:1762-1769.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1762-1769
    • Wang, B.1    Gonzalez, A.2    Benoist, C.3    Mathis, D.4
  • 21
    • 0025833190 scopus 로고
    • Morphological analysis of selective destruction of pancreatic beta cells by cytotoxic T lymphocytes in NOD mice
    • Hayakawa, M., K. Yokono, M. Nagata, N. Hatamori, W. Ogawa, A. Miki, H. Mizoguti, and S. Baba. 1991. Morphological analysis of selective destruction of pancreatic beta cells by cytotoxic T lymphocytes in NOD mice. Diabetes. 40: 1210-1217.
    • (1991) Diabetes , vol.40 , pp. 1210-1217
    • Hayakawa, M.1    Yokono, K.2    Nagata, M.3    Hatamori, N.4    Ogawa, W.5    Miki, A.6    Mizoguti, H.7    Baba, S.8
  • 22
    • 0026692974 scopus 로고
    • Studies on autoimmunity for T-cell-mediated beta cell destruction
    • Nagata, M., and J.-W. Yoon. 1992. Studies on autoimmunity for T-cell-mediated beta cell destruction. Diabetes. 41:998-1008.
    • (1992) Diabetes , vol.41 , pp. 998-1008
    • Nagata, M.1    Yoon, J.-W.2
  • 23
    • 0027170778 scopus 로고
    • Presentation of beta cell antigens to CD4+ and CD8+ T cells of non-obese diabetic mice
    • Shimizu, J., O. Kanagawa, and E. Unanue. 1993. Presentation of beta cell antigens to CD4+ and CD8+ T cells of non-obese diabetic mice. J. Immunol. 151:1723-1730.
    • (1993) J. Immunol. , vol.151 , pp. 1723-1730
    • Shimizu, J.1    Kanagawa, O.2    Unanue, E.3
  • 24
    • 0028294143 scopus 로고
    • Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta cells in NOD mice
    • Nagata, M., P. Santamaria, T. Kawamura, T. Utsugi, and J.-W. Yoon. 1994. Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta cells in NOD mice. J. Immunol. 152:2042-2050.
    • (1994) J. Immunol. , vol.152 , pp. 2042-2050
    • Nagata, M.1    Santamaria, P.2    Kawamura, T.3    Utsugi, T.4    Yoon, J.-W.5
  • 25
    • 0028931879 scopus 로고
    • Beta cell-cytotoxic CD8+ T-cells from nonobese diabetic mice use highly homologous T-cell receptor α-chain CDR3 sequences
    • Santamaria, P., T. Utsugi, B.-J. Park, N. Averill, and J.-W. Yoon. 1995. Beta cell-cytotoxic CD8+ T-cells from nonobese diabetic mice use highly homologous T-cell receptor α-chain CDR3 sequences. J. Immunol. 154:2494-2503.
    • (1995) J. Immunol. , vol.154 , pp. 2494-2503
    • Santamaria, P.1    Utsugi, T.2    Park, B.-J.3    Averill, N.4    Yoon, J.-W.5
  • 26
    • 0030588572 scopus 로고    scopus 로고
    • Acceleration of spontaneous diabetes in TCRβ-transgenic nonobese diabetic mice by beta cell-cytotoxic CD8+ T-cells expressing identical endogenous TCR α chains
    • Verdaguer, J., J.-W. Yoon, B. Anderson, N. Averill, T. Utsugi, B.-J. Park, and P. Santamaria. 1996. Acceleration of spontaneous diabetes in TCRβ-transgenic nonobese diabetic mice by beta cell-cytotoxic CD8+ T-cells expressing identical endogenous TCR α chains. J. Immunol. 157:4726-4735.
    • (1996) J. Immunol. , vol.157 , pp. 4726-4735
    • Verdaguer, J.1    Yoon, J.-W.2    Anderson, B.3    Averill, N.4    Utsugi, T.5    Park, B.-J.6    Santamaria, P.7
  • 29
    • 0026099210 scopus 로고
    • CD8+ T cell homing to the pancreas in the nonobese diabetic mouse is CD4+ T cell-dependent
    • Thivolet, C., A. Bendelac, P. Bedossa, J.F. Bach, and C. Carnaud. 1991. CD8+ T cell homing to the pancreas in the nonobese diabetic mouse is CD4+ T cell-dependent. J. Immunol. 146:85-93.
    • (1991) J. Immunol. , vol.146 , pp. 85-93
    • Thivolet, C.1    Bendelac, A.2    Bedossa, P.3    Bach, J.F.4    Carnaud, C.5
  • 30
    • 0029558631 scopus 로고
    • Pancreatic expression of B7 co-stimulatory molecules in the non-obese diabetic mouse
    • Stephens, L.A, and T.W.H. Kay. 1995. Pancreatic expression of B7 co-stimulatory molecules in the non-obese diabetic mouse. Int. Immunol. 7:1885-1895.
    • (1995) Int. Immunol. , vol.7 , pp. 1885-1895
    • Stephens, L.A.1    Kay, T.W.H.2
  • 31
    • 0029982537 scopus 로고    scopus 로고
    • Genetic analysis of autoimmune disease
    • Vyse, T.J., and J.A. Todd. 1996. Genetic analysis of autoimmune disease. Cell. 85:311-318.
    • (1996) Cell , vol.85 , pp. 311-318
    • Vyse, T.J.1    Todd, J.A.2
  • 32
    • 0029783716 scopus 로고    scopus 로고
    • Major histocompatibility complex class I-restricted infiltration and destruction of pancreatic islets by NOD mouse-derived β-cell cytotoxic CD8+ T-cell clones in vivo
    • Utsugi, T., J.-W. Yoon, B.-J. Park, M. Imamura, N. Averill, S. Kawazu, and P. Santamaria. 1996. Major histocompatibility complex class I-restricted infiltration and destruction of pancreatic islets by NOD mouse-derived β-cell cytotoxic CD8+ T-cell clones in vivo. Diabetes. 45: 1121-1131.
    • (1996) Diabetes , vol.45 , pp. 1121-1131
    • Utsugi, T.1    Yoon, J.-W.2    Park, B.-J.3    Imamura, M.4    Averill, N.5    Kawazu, S.6    Santamaria, P.7
  • 33
    • 0030779118 scopus 로고    scopus 로고
    • A mechanism for the MHC-linked resistance to autoimmunity
    • Schmidt, D., J. Verdaguer, N. Averill, and P. Santamaria. 1997. A mechanism for the MHC-linked resistance to autoimmunity. J. Exp. Med. 186:1059-1075.
    • (1997) J. Exp. Med. , vol.186 , pp. 1059-1075
    • Schmidt, D.1    Verdaguer, J.2    Averill, N.3    Santamaria, P.4
  • 35
    • 0022972464 scopus 로고
    • A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes
    • Spevik, T., and J. Niessen-Meyer. 1986. A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. J. Immunol. Methods. 95:99-106.
    • (1986) J. Immunol. Methods , vol.95 , pp. 99-106
    • Spevik, T.1    Niessen-Meyer, J.2
  • 36
    • 0011984986 scopus 로고
    • Granule enzyme exocytosis assay for cytotoxic T lymphocyte activation
    • J.E. Coligan, A.M. Krusbeek, D.H. Margulies, E.M. Shevach, and W. Strober, editors. John Wiley and Sons, New York
    • Taffs, R., and M. Sitkovsky. 1992. Granule enzyme exocytosis assay for cytotoxic T lymphocyte activation. In Current Protocols in Immunology. J.E. Coligan, A.M. Krusbeek, D.H. Margulies, E.M. Shevach, and W. Strober, editors. John Wiley and Sons, New York. 3.16.1-3.16.8.
    • (1992) Current Protocols in Immunology , pp. 3161-3168
    • Taffs, R.1    Sitkovsky, M.2
  • 37
    • 0028347458 scopus 로고
    • Intracerebral cytokine niRNA expression during fatal and non-fatal alpha-virus encephalitis suggests a predominant type 2 T cell response
    • Wesselingh, S.L., B. Levine, R.J. Fox, S. Choi, and D.E. Griffin. 1994. Intracerebral cytokine niRNA expression during fatal and non-fatal alpha-virus encephalitis suggests a predominant type 2 T cell response. J. Immunol. 152:1289-1297.
    • (1994) J. Immunol. , vol.152 , pp. 1289-1297
    • Wesselingh, S.L.1    Levine, B.2    Fox, R.J.3    Choi, S.4    Griffin, D.E.5
  • 38
    • 0023900635 scopus 로고
    • Tolerance in T cell receptor transgenic mice involves deletion of nonmature CD4+CD8+ thymocytes
    • Kisielow, P., H. Bluthmann, U.D. Staerz, M. Steinmetz, and H. von Boehmer. 1988. Tolerance in T cell receptor transgenic mice involves deletion of nonmature CD4+CD8+ thymocytes. Nature (Lond.). 333:742-746.
    • (1988) Nature (Lond.) , vol.333 , pp. 742-746
    • Kisielow, P.1    Bluthmann, H.2    Staerz, U.D.3    Steinmetz, M.4    Von Boehmer, H.5
  • 39
    • 0024356811 scopus 로고
    • Phenotypic differences between αβ vs β T-cell receptor transgenic mice undergoing negative selection
    • Berg, L.J., B. Fazekas de St. Groth, A.M. Pullen, and M.M. Davis. 1989. Phenotypic differences between αβ vs β T-cell receptor transgenic mice undergoing negative selection. Nature (Lond.). 340:559-562.
    • (1989) Nature (Lond.) , vol.340 , pp. 559-562
    • Berg, L.J.1    De Fazekas St. Groth, B.2    Pullen, A.M.3    Davis, M.M.4
  • 40
    • 0024428184 scopus 로고
    • Antigen/MHC-specific T-cells are preferentially exported from the thymus in the presence of their MHC ligand
    • Berg, L.J., A.M. Pullen, B. Fazekas de St. Groth, D. Mathis, C. Benoist, and M.M. Davis. 1989. Antigen/MHC-specific T-cells are preferentially exported from the thymus in the presence of their MHC ligand. Cell. 58:1035-1046.
    • (1989) Cell , vol.58 , pp. 1035-1046
    • Berg, L.J.1    Pullen, A.M.2    De Fazekas St. Groth, B.3    Mathis, D.4    Benoist, C.5    Davis, M.M.6
  • 41
    • 0024307348 scopus 로고
    • Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen
    • Pircher, H., K. Burki, R. Lang, H. Hengartner, and R.M. Zinkernagel. 1989. Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature (Lond.). 342:559-561.
    • (1989) Nature (Lond.) , vol.342 , pp. 559-561
    • Pircher, H.1    Burki, K.2    Lang, R.3    Hengartner, H.4    Zinkernagel, R.M.5
  • 42
    • 0025184378 scopus 로고
    • Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities
    • Ohashi, P.S., H. Pircher, K. Bürki, R.M. Zinkernagel, and H. Hengartner. 1990. Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities. Nature (Lond.). 346:861-863.
    • (1990) Nature (Lond.) , vol.346 , pp. 861-863
    • Ohashi, P.S.1    Pircher, H.2    Bürki, K.3    Zinkernagel, R.M.4    Hengartner, H.5
  • 43
    • 0023724209 scopus 로고
    • Positive and negative selection of an antigen receptor on T-cells in transgenic mice
    • Sha, W., C. Nelson, R. Newberry, D. Kranz, J. Russell, and D. Loh. 1988. Positive and negative selection of an antigen receptor on T-cells in transgenic mice. Nature (Lond.). 336: 73-76.
    • (1988) Nature (Lond.) , vol.336 , pp. 73-76
    • Sha, W.1    Nelson, C.2    Newberry, R.3    Kranz, D.4    Russell, J.5    Loh, D.6
  • 44
    • 0026658962 scopus 로고
    • Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of non-obese diabetic (NOD) mice. The NOD MHC is dominant for insulitis and cyclophosphamide-induced diabetes
    • Wicker, L.S., M.C. Appel, F. Dotta, A. Pressey, B.J. Miller, N.H. DeLarato, P.A. Fischer, R.C. Boltz, Jr., and L.B. Peterson. 1992. Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of non-obese diabetic (NOD) mice. The NOD MHC is dominant for insulitis and cyclophosphamide-induced diabetes. J. Exp. Med. 176:67-77.
    • (1992) J. Exp. Med. , vol.176 , pp. 67-77
    • Wicker, L.S.1    Appel, M.C.2    Dotta, F.3    Pressey, A.4    Miller, B.J.5    DeLarato, N.H.6    Fischer, P.A.7    Boltz Jr., R.C.8    Peterson, L.B.9
  • 45
    • 0030890588 scopus 로고    scopus 로고
    • Cell death mediators in autoimmune diabetes: No shortage of suspects
    • Benoist, C., and D. Mathis. 1997. Cell death mediators in autoimmune diabetes: no shortage of suspects. Cell. 89:1-3.
    • (1997) Cell. , vol.89 , pp. 1-3
    • Benoist, C.1    Mathis, D.2
  • 48
    • 0029811733 scopus 로고    scopus 로고
    • Chemokine receptors and T cell chemotaxis
    • Mackay, C.R. 1996. Chemokine receptors and T cell chemotaxis. J. Exp. Med. 184:799-802.
    • (1996) J. Exp. Med. , vol.184 , pp. 799-802
    • Mackay, C.R.1
  • 49
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher, E.C., and L.J. Picker. 1996. Lymphocyte homing and homeostasis. Science (Wash. DC). 272:60-66.
    • (1996) Science (Wash. DC) , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, L.J.2
  • 50
    • 0028038426 scopus 로고
    • MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation
    • Germain, R. 1994. MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell. 76:287-299.
    • (1994) Cell , vol.76 , pp. 287-299
    • Germain, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.