Polymorphism within a TCRAV family influences the repertoire through class I/II restriction

Journal of Immunology

Volumn 160, Issue 3, 1998, Pages 1204-1211

  Sim, Bee Cheng ^a   Wung, Jay L ^a   Gascoigne, Nicholas R J ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

AMINO ACID ANALYSIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPLEMENTARITY DETERMINING REGION; GENE SEQUENCE; GENETIC POLYMORPHISM; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPECTROSCOPY; T LYMPHOCYTE RECEPTOR GENE; T LYMPHOCYTE SUBPOPULATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; GENE REARRANGEMENT, ALPHA-CHAIN T-CELL ANTIGEN RECEPTOR; GENE REARRANGEMENT, BETA-CHAIN T-CELL ANTIGEN RECEPTOR; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; POLYMORPHISM, GENETIC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; TRANSGENES;

EID: 0031916706     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (55)

1. Robey, E., and B. J. Fowlkes. 1994. Selective events in T cell development. Annu. Rev. Immunol. 12:675.
2. Jameson, S. C., K. A. Hogquist, and M. J. Bevan. 1995. Positive selection of thymocytes. Annu. Rev. Immunol. 13:93.
3. Teh, H. S., P. Kisielow, B. Scott, H. Kishi, Y. Uematsu, H. Bluthmann, and H. von Boehmer. 1988. Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells. Nature 335:229.
4. Sha, W. C., C. A. Nelson, R. D. Newberry, D. M. Kranz, J. H. Russell, and D. Y. Loh. 1988. Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice. Nature 335:271.
5. Berg, L. J., A. M. Pullen, B. Fazekas de St. Groth, D. Mathis, C. Benoist, and M. M. Davis. 1989. Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand. Cell 58:1035.
6. + T cells in transgenic mice expressing a class II MHC-restricted antigen receptor. Nature 341:746.
7. Utsunomiya, Y., J. Bill, E. Palmer, K. Gollob, Y. Takagaki, and O. Kanagawa. 1989. Analysis of a monoclonal rat antibody directed to the α-chain variable region (Vα3) of the mouse T cell antigen receptor. J. Immunol. 143:2602.
8. + T cells by MHC class I molecules. Immunogenetics 35:291.
9. + T cells: evidence that Vα participates in shaping the peripheral T cell repertoire. J. Exp. Med. 174:639.
10. + cells. J. Immunol. 145:1324.
11. Jameson, S. C., P. B. Nakajima, J. L. Brooks, W. Heath, O. Kanagawa, and N. R. J. Gascoigne. 1991. The T cell receptor Vα11 gene family: analysis of allelic sequence polymorphism and demonstration of Jα-region dependent recognition by allele-specific antibodies. J. Immunol. 147:3185.
12. a haplotypes: determination with a Vα2-specific monoclonal antibody. Eur. J. Immunol. 22:399.
13. Saouaf, S. J., M. Katsumata, K. Yui, S. Thayu, N. R. J. Gascoigne, and M. I. Greene. 1994. Azobenzenearsonate hapten specific T cell receptor alpha chain transgenic mice. Transgenics 1:185.
14. Zerrahn, J., W. Held, and D. H. Raulet. 1997. The MHC reactivity of the T cell repertoire prior to positive and negative selection. Cell 88:627.
15. Merkenschlager, M., D. Graf, M. Lovatt, U. Bommhardt, R. Zamoyska, and A. G. Fisher. 1997. How many thymocytes audition for selection? J. Exp. Med. 186:1149.
16. Garcia, K. C., M. Degano, R. L. Stanfield, A. Brunmark, M. R. Jackson, P. A. Peterson, L. Teyton, and I. A. Wilson. 1996. An αβ T cell receptor structure at 2.5Å and its orientation in the TCR-MHC complex. Science 274:209.
17. Garboczi, D. N., P. Ghosh, U. Utz, Q. R. Fan, W. E. Biddison, and D. C. Wiley. 1996. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature 384:134.
18. Sim, B.-C., L. Zerva, M. I. Greene, and N. R. J. Gascoigne. 1996. Control of MHC restriction by TCR Vα CDR1 and CDR2. Science 273:963.
19. Jouvin-Marche, E., I. Hue, P. N. Marche, C. Liebe-Gris, J.-P. Marolleau, B. Malissen, P.-A. Cazenave, and M. Malissen. 1990. Genomic organization of the mouse T cell receptor Vα family. EMBO J. 9:2141.
20. Chou, H. S., M. A. Behlke, S. A. Godambe, J. H. Russell, C. G. Brooks, and D. Y. Loh. 1986. T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments. EMBO J. 5:2149.
21. Wang, K., C.-L. Kuo, K.-C. Cheng, M.-K. Lee, B. Paeper, B. F. Koop, T.-J. Yoo, and L. Hood. 1994. Structural analysis of the mouse T-cell receptor Tcra V2 subfamily. Immunogenetics 40:116.
22. Gahéry-Ségard, H., E. Jouvin-Marche, A. Six, C. Gris-Liebe, M. Malissen, B. Malissen, P. A. Cazenave, and P. N. Marche. 1996. Germline genomic structure of the B10. A mouse Tcra-V2 gene subfamily. Immunogenetics 44:298.
23. Tan, K. N., K. Huang, K. V. Myrick, and G. Tanigawa. 1996. Diversity of the Tcra-V3 gene family in BALB/c mice. Immunogenetics 44:372.
24. Mombaerts, P., A. R. Clarke, M. A. Rudnicki, J. Iacomini, S. Itohara, J. Lafaille, L. Wang, Y. Ichikawa, R. Jaenisch, M. L. Hooper, and S. Tonegawa. 1992. Mutations in T cell receptor genes α and β block thymocyte development at different stages. Nature 360:225.
25. Tan, K.-N., B. M. Datlof, J. A. Gilmore, A. C. Kronman, J. H. Lee, A. M. Maxam, and A. Rao. 1988. The T cell receptor Vα3 gene segment is associated with reactivity to p-azobenzenearsonate. Cell 54:247.
26. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanale-phenol-chloroform extraction. Anal. Biochem. 162: 156.
27. Arden, B., S. P. Clark, D. Kabelitz, and T. W. Mak. 1995. Mouse T-cell receptor variable gene segment families. Immunogenetics 42:501.
28. Koop, B. F., L. Rowen, K. Wang, C. L. Kuo, D. Seto, J. A. Lenstra, S. Howard, W. Shan, P. Deshpande, and L. Hood. 1994. The human T-cell receptor TCRAC/ TCRDC (Cα/Cδ) region: organization, sequence, and evolution of 97.6 kb of DNA. Genomics 19:478.
29. Gorski, J., M. Yassai, X. Zhu, B. Kissela, C. Keever, and N. Flomenberg. 1994. Circulating T cell repertoire complexity in normal individuals and bone marrow recipients analyzed by CDR3 size spectratyping: correlation with immune status. J. Immunol. 152:5109.
30. Sambrook, J., E. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
31. Malissen, M., J. Trucy, E. Jouvin-Marche, P.-A. Cazenave, R. Scollay, and B. Malissen. 1992. Regulation of TCR α and β gene allelic exclusion during T-cell development. Immunol. Today 13:315.
32. Alam, S. M., I. N. Crispe, and N. R. J. Gascoigne. 1995. Allelic exclusion of mouse T cell receptor α chains occurs at the time of thymocyte TCR up-regulation. Immunity 3:449.
33. + T cells. Immunogenetics 36:230.
34. + thymocytes controlled by MHC class II gene products. Nature 336:471.
35. + T cells. Immunogenetics 35:9.
36. + T cells. Science 244:214.
37. + T cells. J. Exp. Med. 170:135.
38. Tomonari, K., O. A. Rosenwasser, and S. P. Fairchild. 1997. The T cell receptor Vβ-specific positive selection: importance of the CDR4. In Viral Superantigens. K. Tomonari, ed. CRC Press, Boca Raton, FL, p. 127.
39. Sim, B.-C, P. J. Travers, and N. R. J. Gascoigne. 1997. Vα3.2 selection in MHC class I mutant mice: evidence for an alternate orientation of TCR-MHC class I interaction. J. Immunol. 159:3322.
40. b) mice. J. Immunol. 138:3991.
41. Iwamoto, A., P. S. Ohashi, H. Pircher, C. L. Walker, E. E. Michalopoulos, F. Rupp, H. Hengartner, and T. W. Mak. 1987. T cell receptor variable gene usage in a specific cytotoxic T cell response: primary structure of the antigen-MHC receptor of four hapten-specific cytotoxic T cell clones. J. Exp. Med. 165: 591.
42. bm-12 molecules. Proc. Natl. Acad. Sci. USA 89:2940.
43. Rock, E. P., P. R. Sibbald, M. M. Davis, and Y. Chien. 1994. CDR3 length in antigen-specific immune receptors. J. Exp. Med. 179:323.
44. Torres-Nagel, N., T. Herrmann, G. Giegerich, K. Wonigeit, and T. Hünig. 1994. Preferential TCR V usage in positive repertoire selection and alloreactivity of rat T-lymphocytes. Int. Immunol. 6:1367.
45. Torres-Nagel, N., A. Deutschländer, T. Herrmann, B. Arden, and T. Hünig. 1997. Control of TCR Vα-mediated positive repertoire selection and alloreactivity by differential Jα usage and CDR3α composition. Int. Immunol. 9:1441.
46. + thymocytes to either CD4 or CD8 lineages. Proc. Natl. Acad. Sci. USA 90:8982.
47. Corbella, P., D. Moskophidis, E. Spanopoulou, C. Mamalaki, M. Tolaini, A. Itano, D. Lans, D. Baltimore, E. Robey, and D. Kioussis. 1994. Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity. Immunity 1:269.
48. Osman, G. E., M. Toda, O. Kanagawa, and L. E. Hood. 1993. Characterization of the T cell receptor repertoire causing collagen arthritis in mice. J. Exp. Med. 177:387.
49. Brodeur, P. H., and R. Riblet. 1984. The immunoglobulin heavy chain variable region (Igh-V) locus in the mouse. I. One hundred Igh-V genes comprise seven families of homologous genes. Eur. J. Immunol. 14:922.
50. Becker, D. M., P. Patten, Y. Chien, T. Yokota, Z. Eshhar, M. Giedlin, N. R. J. Gascoigne, C. Goodnow, R. Wolf, K. Arai, and M. M. Davis. 1985. Variability and repertoire size of T-cell receptor Vα gene segments. Nature 317: 430.
51. Singer, P. A., R. J. McEvilly, R. S. Balderas, F. J. Dixon, and A. N. Theofilopoulos. 1988. T-cell receptor α-chain variable-region haplotypes of normal and autoimmune laboratory mouse strains. Proc. Natl. Acad. Sci. USA 85:7729.
52. Klotz, J. L., R. K. Barth, G. L. Kiser, L. E. Hood, and M. Kronenberg. 1989. Restriction fragment length polymorphisms of the mouse T-cell receptor gene families. Immunogenetics 29:191.
53. Jouvin-Marche, E., M. Goncalves Morgado, N. Trede, P. N. Marche, D. Couez, I. Hue, C. Gris, M. Malissen, and P.-A. Cazenave. 1989. Complexity, polymorphism, and recombination of mouse T-cell receptor α gene families. Immunogenetics 30:99.
54. Gascoigne, N. R. J. 1995. Genomic organization of T cell receptor genes in the mouse. In T Cell Receptors. J. I. Bell, M. J. Owen, and E. Simpson, eds. Oxford University Press, Oxford, U.K., p. 288.
55. 2-terminal animo acid of the T cell receptor α chain on major histocompatibility complex (MHC) class II plus peptide recognition. J. Exp. Med. 185:1919.